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2821
Investigating the preventive effects of pulsed electromagnetic fields on glucocorticoid-induced osteoporosis in rats
Published 2025-01-01“…At 1, 2, 4, and 8 weeks after the last MPSL (or saline) injection, bone mineral density (BMD), bone mineral content (BMC), and the expression levels of bone morphogenetic protein-2 (BMP-2) mRNA and protein in the proximal femur were measured. …”
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2822
Diagnostic Value of Glycosylated Extracellular Vesicle microRNAs in Gastric Cancer
Published 2025-01-01“…The markers also showed excellent performance in indicating perineural invasion status and lymph node metastasis in the testing cohort.Discussion: The model demonstrated high sensitivity and specificity in diagnosing patients with GC, especially in differentiating early-stage GC from benign patients. The five miRNA pairs could also aid in making treatment decisions. …”
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2823
First whole genome report of Mangrovibacter phragmitis PSU-3885–11 isolated from a patient in Thailand
Published 2025-01-01“…The genome contains 4,651 coding sequences, along with 72 tRNA genes and 1 tmRNA. Moreover, comparative genomic analysis showed 99.32 % average nucleotide identity (ANI) similar to M. phragmitis MP23, and several antibiotic resistance genes (ARGs) and mobile genetic elements (MGEs) were identified in the PSU-3885–11 genome which may contribute to its ability to survive in diverse environments, including human hosts. …”
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2824
Systemic delivery of AAV5, AAV8, and AAV9 packaging a C5-12-microdystrophin-FLAG expression cassette in non-human primates
Published 2025-03-01“…AAV8 led to higher levels of microdystrophin-FLAG mRNA and protein in the cardiac ventricles and skeletal muscles when compared to AAV5 or AAV9. …”
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2825
Validation of a Real Time PCR for Classical Swine Fever Diagnosis
Published 2014-01-01“…Furthermore, RNA from CSF virus was not detected in samples of swine originated from the Brazilian CSF-free zone. …”
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2826
Sevoflurane Exacerbates Cognitive Impairment Induced by Aβ1–40 in Rats through Initiating Neurotoxicity, Neuroinflammation, and Neuronal Apoptosis in Rat Hippocampus
Published 2018-01-01“…Interleukin- (IL-) 1β, nuclear factor-κB (NF-κB), and inducible nitric oxide synthase (iNOS) mRNA expression increased after the rats inhaled sevoflurane in the Aβ-treated group (both P<0.01). …”
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2827
Screening of probiotics bacteria from coral reef using co-culture method for controlling vibriosis in tiger shrimp (Penaeus monodon) larvae
Published 2015-04-01“…Partial sequencing of 16S-rRNA showed that 13G1 isolate was similar to V. alginolyticus. …”
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2828
Targeting HVEM-GPT2 axis: a novel approach to T cell activation and metabolic reprogramming in non-small cell lung cancer therapy
Published 2025-02-01“…Lung cancer cells co-cultured with Jurkat T cells were xenografted into nude mice to evaluate tumor growth and metastatic potential. Next, RNA-seq, COIP, Dual-luciferase reporter experiment, and CHIP-seq were used to explore the potential underlying mechanism. …”
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2829
Lactobacillus fermentum B153 from human colostrum modulates intestinal immunity and gut microbiota in obese mice model
Published 2025-02-01“…Intestinal inflammation induced by the high-fat diet was alleviated by L. fermentum B153, as evidenced by the upregulation of E-cadherin and IL-6 mRNA expression, alongside the downregulation of TNF-α mRNA expression. …”
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2830
EPIGENETICS TODAY AND TOMORROW
Published 2015-01-01“…The most known epigenetic mechanisms (signals) are enzymatic DNA methylation, the histone code (various enzymatic histone modifications including acetylation, methylation, phosphorylation, ubiquitination and others), and gene silencing mediated by small RNAs (miRNA, siRNA). Very often all these processes are interconnected or even partially interchangeable. …”
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2831
Halophilic bacteria of salt lakes and saline soils of the Peri-Caspian lowland (Republic of Daghestan) and their biotechnological potential
Published 2021-04-01“…Denitrifying halophilic bacteria of the genus Halomonas and Virgibacillus were identified using microbiological methods and 16S rRNA gene analysis. A new species Halomonas sp. G2 (MW386470) with a similarity of the nucleotide sequences of the 16S rRNA genes is 95 %. …”
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2832
Efficient Differentiation of Mouse Induced Pluripotent Stem Cells into Alveolar Epithelium Type II with a BRD4 Inhibitor
Published 2019-01-01“…As a result, on day 40, the mRNA expression level of Sftpc in the three-dimensional culture was maintained at the same level as on day 26 and shown to be further increased by the addition of JQ1, with 39% of the cells found to express proSPC, showing that differentiation efficiency could be further increased. …”
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2833
No rumen fermentation profiles and associated microbial diversities difference were found between Hu sheep and Karakul sheep fed a cottonseed hull diet
Published 2025-01-01“…To analyze the dynamics of rumen fermentation, 16S rRNA sequencing and metabolomics methods were employed, alongside measurements of rumen fermentation parameters and cellulase activity. …”
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2834
The TB27 Transcriptomic Model for Predicting Mycobacterium tuberculosis Culture Conversion
Published 2025-01-01“… Rationale: Treatment monitoring of tuberculosis patients is complicated by a slow growth rate of Mycobacterium tuberculosis. Recently, host RNA signatures have been used to monitor the response to tuberculosis treatment. …”
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2835
Optimized genotyping method for identification of bacterial contaminants in pharmaceutical industry
Published 2016-06-01“…Molecular identification of bacterial contaminants based on DNA sequencing of the hypervariable 16SrRNA gene has been introduced recently. The aim of this study is to investigate the suitability of gene sequencing using our selection of PCR primers and conditions for rapid and accurate bacterial identification in pharmaceutical industry quality control.…”
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2836
Advances in personalized gastroenterology and hepatology 2016
Published 2016-08-01“…On the other hand, using high throughput array and other technologies, it is possible to simultaneously analyze thousands of genes (DNA) or gene products (RNA and proteins), resulting in an individual gene or gene expression profile (‘signature’) or to characterize the individual microbiome and its pathogenetic potential. …”
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2837
DNA Polymerase e - More Than a Polymerase
Published 2003-01-01“…During this process, DNA polymerase a lays down RNA-DNA primers that are utilized by DNA polymerases d and e for the bulk DNA synthesis. …”
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2838
The Clinical and Cellular Impact of RBMS2 on the Progression and Prognosis of Kidney Renal Clear Cell Carcinoma
Published 2023-01-01“…This research delves into the implications of the RNA binding motif, single stranded interacting protein 2 (RBMS2)—a gene associated with tumor-suppressing functions—in the context of kidney renal clear cell carcinoma (ccRCC). …”
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2839
Primary extranodal NK/T cell lymphoma of stomach: A case report and review of literature
Published 2023-07-01“…Partial gastrectomy done and histopathology showed transmural infiltration by intermediate size atypical lymphoid cells which are immunopositive for CD3, CD56, TIA, EBV-encoded RNA (EBER) and negative for CD4, CD8, CD20. A diagnosis of extranodal NK/T cell lymphoma nasal type was made.…”
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2840
Nongenomic Mechanisms of PTEN Regulation
Published 2012-01-01“…Here we discuss PTEN ubiquitination, PTEN complex formation with components of the adherens junction, PTEN nuclear localization, and microRNA regulation of PTEN as essential regulatory mechanisms that determine PTEN function independent of gene mutations and epigenetic events.…”
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