BNT162b2 COVID-19 Vaccine Induced Immune Thrombocytopenic Purpura by A. K. Ghosh, S. Bhushan, L. D. R. Lopez, D. Sampat, Z. Salah, C. A. Hatoum

“…Herein, we present a patient who presented with severe ITP with a platelet count of 0 after receiving the second dose of the BNT162b2 mRNA COVID-19 vaccine (also known as the Pfizer BioNTech). …”
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New trends in the treatment of androgenetic alopecia by Szymon Leonik, Michał Smoczok, Beata Bergler-Czop

“…This publication reviews the use of minoxidil, 5a-reductase inhibitors (applied orally, topically and by injection), tretinoin, botulinum toxin, microRNA, and osteopontin as treatment options for androgenetic alopecia in men.…”
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2019–2020 Florida Citrus Production Guide: Exocortis, Cachexia, and Other Viroids by Ozgur Batuman, Amit Levy, Ronald H. Brlansky

“…Viroids are small, infectious circular-RNA molecules. Exocortis causes dwarfing and bark scaling on rootstocks such as trifoliate orange and many of its hybrids such as Carrizo citrange, Rangpur lime, and others. …”
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Theorem on the union of two topologically flat cells of codimension 1 in ℝn by A. V. Chernavsky

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Ribosomal Alteration-Derived Signals for Cytokine Induction in Mucosal and Systemic Inflammation: Noncanonical Pathways by Ribosomal Inactivation by Yuseok Moon

“…Ribosomal inactivation damages 28S ribosomal RNA by interfering with its functioning during gene translation, leading to stress responses linked to a variety of inflammatory disease processes. …”
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SHP2 is essential for the progesterone-promoted proliferation and migration in breast cancer cell lines by Hui-Chen Wang, Hui-Chen Wang, Wen-Sen Lee, Wen-Sen Lee, Wen-Sen Lee, Wen-Sen Lee

“…Immunoprecipitation assay and Western blot analysis were performed to evaluate protein-protein interaction and protein expression, respectively. Small interfering RNA (siRNA) technique was used to knock down protein expression.ResultsKnockdown of SHP2 expression abolished the P4-promoted cell proliferation and migration in T47D, MCF and BT-483 cell lines, suggesting that presence of SHP2 is essential for the P4-increased proliferation and migration of breast cancer cell lines. …”
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Efek Pemberian Suntikan Subkutan Vitamin C Terhadap Luka Insisi Dermal by Surya Darma, Menker Manjas, Deddy Saputra, Salmiah Agus, Erkadius Erkadius

“…Selain itu Vitaimin C juga berfungsi meregulasi dan menstabilkan trankripsi gen mRNA prokolagen pada proses pembentukan kolagen di dermis. …”
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Defects at the Posttranscriptional Level Account for the Low TCRζ Chain Expression Detected in Gastric Cancer Independently of Caspase-3 Activity by Ana Aguinaga-Barrilero, Patricia Castro-Sánchez, Ignacio Juárez, Alberto Gutiérrez-Calvo, Noelia Rodríguez-Pérez, Adela Lopez, Remedios Gómez, José M. Martin-Villa

“…Samples were subjected to cytofluorimetry, Western blot analysis, TCRζ cDNA sequencing experiments, measurement of TCRζ mRNA levels, and caspase-3 activity assays. Results. …”
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The promising role of nanopore sequencing in cancer diagnostics and treatment by Xinming Su, Qingyuan Lin, Bin Liu, Chuntao Zhou, Liuyi Lu, Zihao Lin, Jiahua Si, Yuemin Ding, Shiwei Duan

“…In the context of DNA analysis, nanopore sequencing excels in identifying structural variations (SVs), copy number variations (CNVs), gene fusions within SVs, and mutations in specific genes, including those involving DNA modifications and DNA adducts. In the field of RNA research, nanopore sequencing proves invaluable in discerning differentially expressed transcripts, uncovering novel elements linked to transcriptional regulation, and identifying alternative splicing events and RNA modifications at the single-molecule level. …”
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Comprehensive multi-omics analysis showed that CDC6 is a potential prognostic and immunotherapy biomarker for multiple cancer types including HCC by Chenxuan Li, En-di Zhang, Rui Yu, Bo Yuan, Yunxin Yang, Zhong Zeng, Hanfei Huang

“…Methods: Explored CDC6 mRNA and protein expression in normal human tissues and tumors using TCGA, GTEx, and HPA. …”
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The Class III PI3K/Beclin-1 Autophagic Pathway Participates in the mmLDL-Induced Upregulation of ETA Receptor in Mouse Mesenteric Arteries by Xi Xie, Chen Chen, Cang-Bao Xu, Jie Lin, Lei Cao, Gen Chen, Jie Li

“…In addition to upregulating the protein levels of Class III PI3K, Beclin-1, and LC3 II/I and downregulating that of p62, mmLDL significantly increased the mRNA expression and protein level of the ETA receptor and increased the protein level of p-NF-κB. …”
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Quzhou Aurantii Fructus Flavonoids Ameliorate Inflammatory Responses, Intestinal Barrier Dysfunction in DSS-Induced Colitis by Modulating PI3K/AKT Signaling Pathway and Gut Microbi... by Wang H, Huang W, Pan X, Tian M, Chen J, Liu X, Li Q, Qi J, Ye Y, Gao L

“…Additionally, the influence of QAFF on the gut microbiome was explored through 16S ribosomal RNA (rRNA) sequencing. The alterations in endogenous metabolites were detected by untargeted metabolomics, and their potential correlation with intestinal flora was then examined utilizing Spearman correlation analysis. …”
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Prolonged Helium Postconditioning Protocols during Early Reperfusion Do Not Induce Cardioprotection in the Rat Heart In Vivo: Role of Inflammatory Cytokines by Gezina Tanya Mei Ling Oei, Hamid Aslami, Raphaela Priscilla Kerindongo, Renske Johanna Steenstra, Charlotte Jacqueline Peter Beurskens, Anita Maria Tuip-de Boer, Nicole Petra Juffermans, Markus Werner Hollmann, Benedikt Preckel, Nina Claudia Weber

“…Effects of helium postconditioning protocols on infarct size and the ischemia/reperfusion-induced immune response were investigated by measurement of protein and mRNA levels of proinflammatory cytokines. Rats were anesthetized with S-ketamine (150 mg/kg) and diazepam (1.5 mg/kg). …”
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FTO attenuates TNF-α-induced damage of proximal tubular epithelial cells in acute pancreatitis-induced acute kidney injury via targeting AQP3 in an N6-methyladenosine-dependent man... by Xinghui Li, Qi Liang, Lu Liu, Shujun Chen, Yong Li, Yu Pu

“…The viability and apoptosis of PTECs under various conditions, and reactive oxygen species (ROS), superoxide dismutase (SOD), and malonaldehyde (MDA) levels within these cells were measured using commercial assay kits and flow cytometry. Methylated RNA immunoprecipitation and mRNA stability assays were performed to elucidate the mechanism of FTO-mediated N6-methyladenosine (m6A) modification. …”
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Hypoxia-induced circPLOD2a/b promotes the aggressiveness of glioblastoma by suppressing XIRP1 through binding to HuR by Aixin Yu, Yiqi Wang, Chao Duan, Jun Qin, Miaomiao Liao, Haiyan Zhu, Junrong Lei, Jun Liu, Zehao Yang, Li Yu, Hui Gui, Jinxin Xin, Weiwei Tao, Wendai Bao, Zhiqiang Dong

“…The protein partners and downstream molecules were investigated by RNA-pulldown, mass spectrometry and RNA-seq. Mechanistically, HIF1α induces the expression of circPLOD2a and b, which competitively bind to HuR, causing a degradation of XIRP1 in vitro and in vivo. …”
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RCE-IFE: recursive cluster elimination with intra-cluster feature elimination by Cihan Kuzudisli, Burcu Bakir-Gungor, Bahjat Qaqish, Malik Yousef

“…For a set of gene expression, microRNA (miRNA) expression, and methylation datasets, the performance of RCE-IFE is comparatively evaluated with RCE-IFE-SVM (the SVM-adapted version of RCE-IFE) and SVM-RCE. …”
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Feedback loop centered on MAF1 reduces blood–brain barrier damage in sepsis-associated encephalopathy by Xuebiao Wei, Wenqiang Jiang, Zhonghua Wang, Yichen Li, Yuanwen Jing, Yongli Han, Linqiang Huang, Shenglong Chen

“…Abstract Background A previous study found that MAF1 homolog, a negative regulator of RNA polymerase III (MAF1), protects the blood–brain barrier (BBB) in sepsis-associated encephalopathy (SAE); however, the related molecular mechanisms remain unclear. …”
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miR-1233-3p Inhibits Angiopoietin-1-Induced Endothelial Cell Survival, Migration, and Differentiation by Veronica Sanchez, Sharon Harel, Anas Khalid Sa’ub, Dominique Mayaki, Sabah N. A. Hussain

“…Our high-throughput screening of miRNAs regulated by Ang-1 exposure in human umbilical vein endothelial cells (HUVECs) has identified miR-1233-3p as a mature miRNA whose cellular levels are significantly downregulated in response to Ang-1 exposure. …”
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Exploration of the mechanism of 5-Methylcytosine promoting the progression of hepatocellular carcinoma by Qiyao Zhang, Zhen Cao, Yuting He, Ziwen Liu, Wenzhi Guo

“…5-Methylcytosine (m5C) is a ubiquitous RNA modification that is closely related to various cellular functions. …”
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The Role of Caspase-4 and NLRP1 in MCF7 Cell Pyroptosis Induced by hUCMSC-Secreted Factors by Yang Jiao, Linlin Wang, Lin Lu, Jianjun Liu, Xin Li, Hongbo Zhao, Zongliu Hou, Bingrong Zheng

“…Further, we investigated the role of CASP4 and NLRP1 in MCF7 cell pyroptosis induced by hUCMSC-secreted factors using shRNA-mediated transfection of CASP4 or NLRP1 in MCF7 cells. …”
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