Hepatic Cerebroside Sulfotransferase Is Induced by PPARα Activation in Mice by Takefumi Kimura, Takero Nakajima, Yuji Kamijo, Naoki Tanaka, Lixuan Wang, Atsushi Hara, Eiko Sugiyama, Eiji Tanaka, Frank J. Gonzalez, Toshifumi Aoyama

“…Furthermore, increases in CST mRNA levels were correlated with mRNA elevations of several known PPARα target genes, and such changes were not observed for other sulfatide-metabolism enzymes in the liver. …”
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Toll-like receptor upregulation in liver and peripheral blood mononuclear cells of patients with amoebic liver abscess by Sandhya Khunger, Abhishek Mewara, Upninder Kaur, Ajay Duseja, Pallab Ray, Naveen Kalra, Navneet Sharma, Rakesh Sehgal

“…Blood samples from 100 ALA and 41 healthy individuals were collected. mRNA expression of TLR 1 to 9 genes was measured using reverse transcriptase polymerase chain reaction (RT-PCR). …”
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Polysaccharide extract from Rosa laevigata fruit attenuates inflammatory obesity by targeting redox balance and gut interface in high-fat diet-fed rats by Xuejiao Zhang, Chenzhong Jin, Han Liu, Yihong Hu, Yunyun Zhou, Weiguo Wu, Si Qin

“…Moreover, 16S rRNA sequencing coupled with metagenome sequencing showed that RLPs had significantly reduced the ratio of Firmicutes/Bacteroidetes from 8.01 to 2.37, and significantly increased the relative abundances of Alistipes, Prevotella, and Akkermansia from 0.36 %, 1.10 % and 2.61 % to 0.65 %, 2.37 % and 4.42 %, respectively. …”
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Molecular Identification of Mycobacterium Species of Public Health and Veterinary Importance from Cattle in the South State of México by Adrian Zaragoza Bastida, Nallely Rivero Pérez, Benjamín Valladares Carranza, Keila Isaac-Olivé, Pablo Moreno Pérez, Horacio Sandoval Trujillo, Ninfa Ramírez Durán

“…The objective of this study was to isolate and identify nontuberculous mycobacteria species from cattle of local herds in the south region of the State of Mexico through the identification and detection of the 100 bp molecular marker in the 23S rRNA gene with subsequent sequencing of the 16S rRNA gene. …”
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Dendrobium chrysotoxum Lindl. Alleviates Diabetic Retinopathy by Preventing Retinal Inflammation and Tight Junction Protein Decrease by Zengyang Yu, Chenyuan Gong, Bin Lu, Li Yang, Yuchen Sheng, Lili Ji, Zhengtao Wang

“…DC reduced the increased retinal mRNA expressions of intercellular adhesion molecule-1 (ICAM-1), tumor necrosis factor α (TNFα), interleukin- (IL-) 6, and IL-1β in diabetic rats. …”
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Erbin Regulates Tissue Factors Through Ras/Raf Pathway in Coagulation Disorders in Sepsis by Yang C, Lei C, Jing G, Xia Y, Zhou H, Wu D, Zuo J, Gong H, Wang X, Dong Y, Aidebaike D, Wu X, Song X

“…At the animal level, the cecal ligation and perforation (CLP) model was constructed in mice, and the inflammatory response and coagulation disorder of mice were observed by hematoxylin-eosin (HE) staining, immunohistochemistry, ELISA, and automatic hemagglutination analyzer. The protein and mRNA expression level were detected by Western blot and qPCR. …”
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Prospect of Induced Pluripotent Stem Cell Genetic Repair to Cure Genetic Diseases by Jeanne Adiwinata Pawitan

“…This review discusses the various technologies to repair the genetic aberration in patient-derived iPSC, or to prevent the genetic aberration to cause further damage in the iPSC-derived cells, such as Zn finger and TALE nuclease genetic editing, RNA interference technology, exon skipping, and gene transfer method. …”
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Rapid Diagnosis of Bacterial Infections Using Technologies Based on Nucleic Acid Detection by François J Picard, Michel G Bergeron

“…Novel diagnostic tests based on the detection of nucleic acids (DNA or RNA) offer a great potential for the rapid (approximately 1 h) diagnosis of bacterial infections. …”
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Attractor for a Reaction-Diffusion System Modeling Cancer Network by Xueyong Chen, Jianwei Shen, Hongxian Zhou

“…A reaction-diffusion cancer network regulated by microRNA is considered in this paper. We study the asymptotic behavior of solution and show the existence of global uniformly bounded solution to the system in a bounded domain Ω⊂Rn. …”
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Perspectives of International Human Epigenome Consortium by Jae-Bum Bae

“…Epigenome data will cover from whole genome bisulfite sequencing, histone modification, and chromatin access information to miRNA-seq. The final goal of IHEC is the production of reference maps of human epigenomes for key cellular status relevant to health and disease.…”
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Innovative Approaches to Suppressing Pseudomonas aeruginosa Growth and Virulence: Current Status and Future Directions by Sandip Patil, Xiaowen Chen, Feiqiu Wen

“…Additionally, novel approaches, including RNA interference, CRISPR-Cas systems, and nanotechnology, show promise in preclinical studies. …”
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TRANSLATIONAL ENHANCERS FOR PLANT GENE ENGINEERING by A. V. Kochetov, E. A. Filipenko, O. G. Smirnova, V. K. Shumny

“…In particular, 5′-UTR is an important element, as it influences mRNA translation efficiency and the protein synthesis rate. …”
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Pyrosequencing Assay to Rapidly Detect Clarithromycin Resistance Mutations in Canadian Helicobacter pylori Isolates by R Slinger, L Yan, F Chan, K Forward, G Cooper-Lesins, L Best, D Haldane, S Veldhuyzen van Zanten

“…BACKGROUND: Mutations at positions 2142 or 2143 in the two-copy 23S ribosomal RNA gene of Helicobacter pylori are highly predictive of in vitro clarithromycin resistance and failure of clarithromycin-containing treatment regimens.…”
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PHYLOGENETIC RELATIONSHIPS AMONG SEVERAL NORTH-ASIAN SPECIES OF THE GENUS AQUILEGIA ACCORDING TO VARIOUS MOLECULAR MARKERS by A. S. Erst, O. V. Vaulin

“…Molecular study of the nucleotide sequence of the rpl32-trnL spacer and the ITS1-ITS2 fragment of rRNA genes in eight species of the genus Aquilegia sampled in Northern Asia has shown that populations of A. borodinii and A. jucunda from various localities are genetically diverse. …”
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Gene Expression of ERβ Isoforms in Laser Microdissected Human Breast Cancers: Implications for Gene Expression Analyses by Michele Cummings, James Iremonger, Caroline A. Green, Abeer M. Shaaban, Valerie Speirs

“…This is largely due to discordant data between mRNA and protein studies as well as failure to take into account the biologically distinct ERβ isoforms and their heterogeneous expression profile.…”
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The Effects of Addition of Mononucleotides on Sma nuc Endonuclease Activity by Julia Romanova, Maria Filimonova

“…Examination of the effects of mononucleotides on Sma nuc endonuclease originated from Gram negative bacterium Serratia marcescens displayed that any mononucleotide produced by Sma nuc during hydrolysis of DNA or RNA may regulate the enzyme activity affecting the RNase activity without pronounced influence on the activity towards DNA. …”
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Idiopathic Multicentric Castleman Disease following SARS-CoV-2 Vaccination by Chien-Yu Ker, Hung-Wei Liu, Yu-Chieh Su, Pang-Yu Lai*

“…The increased IL-6 signaling in iMCD, increase in IL-6 after mRNA vaccines, and hyperactivation of IL-6 as a critical mediator in COVID-19 infection demonstrate a shared mechanism underlying inflammatory cytokine dysregulation. …”
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Therapeutic landscape for inherited ocular diseases: current and emerging therapies by Hwei Wuen Chan, Jaslyn Oh, Bart Leroy

“…Recent success in adeno-associated virus-based gene therapy, voretigene neparvovec (Luxturna®) for RPE65-related IRDs, has heralded rapid evolution in gene therapy platform technologies and strategies, from gene augmentation to RNA editing, as well as gene agnostic approaches such as optogenetics. …”
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Preeclampsia, Natural History, Genes, and miRNAs Associated with the Syndrome by Laura Parada-Niño, Luisa Fernanda Castillo-León, Adrien Morel

“…The causes of the pathology are unclear; nevertheless, numerous approaches, including next-generation sequencing, association, and case control and miRNA studies, have shed light on the genetic/molecular basis of PE. …”
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Widespread Arterial Thrombosis after ChAdOx1 nCov-19 Vaccination by Giorgio Berlot, Ariella Tomasini, Cristina La Fata, Stefania Pintacuda, Sara Rigutti, Anna Falanga

“…Vaccine-induced thrombotic thrombocytopenia is an uncommon complication of COVID-19 vaccines using adenovirus mRNA carriers and has been associated with thrombosis of the cerebral venous sinuses and portal system. …”
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