Efficacy and safety of an Albuvirtide-based regimen for preventing mother-to-child transmission of multidrug-resistant HIV: a case report by Na Li, Shifei Wen, Fangfang Zhu, Guirong Liu, Daqing Zhu

“…By the prenatal period (40 weeks), HIV RNA became undetectable, and CD4 cells had risen to 348 cells/µL. …”
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Molecular Identification, Histopathology and Antibiotic Susceptibility Profiling of Aeromonas veronii Isolated from Oreochromis niloticus in Bangladesh by Sayed Mashequl Bari, Mohammad Muttakinul Islam, Aktia Amina, Marufa Khatun, A. M. Shahabuddin

“…Moreover, molecular analysis of the bacterial conserved region 16S rRNA also confirmed these isolates as A. veronii. …”
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Transplantation of Neural Stem Cells Cotreated with Thyroid Hormone and GDNF Gene Induces Neuroprotection in Rats of Chronic Experimental Allergic Encephalomyelitis by Xiaoqing Gao, Guangqiang Hu, Li Deng, Guangbi Fan, Chaoxian Yang, Jie Du

“…Furthermore, T3/NSCs and GDNF-T3/NSCs grafting increased the expression of mRNA for PDGFαR, GalC, and MBP in lesion areas of brain compared with NSCs grafting, and the expression of mRNA for GalC and MBP in GDNF-T3/NSCs group was higher than that in T3/NSCs group. …”
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Chloroplast Genome Sequencing and Comparative Analysis of Six Medicinal Plants of Polygonatum by Jinchen Yao, Zhaohuan Zheng, Tao Xu, Duomei Wang, Jingzhe Pu, Yazhong Zhang, Liangping Zha

“…Among the 127–131 genes contained in the genomes, 84–85 are protein‐coding genes, 37–38 are transfer RNA genes, and 6–8 are ribosomal RNA genes. The genomes contained 64–76 simple sequence repeats (SSRs) and 36–62 long repetitive sequences. …”
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Gastric Microbiota in Patients with Dyspepsia: Metatranscriptomic Analysis by Е. А. Kupriyanova, М. I. Markelova, Е. А. Ziyatdinova, D. D. Safina, A. G. Safin, I. М. Alieva, R. К. Zalyalov, R. А. Abdulkhakov, Т. V. Grigoryeva, S. R. Abdulkhakov

“…The presence of H. pylori infection was confirmed by PCR; RNA was isolated and then libraries were prepared for metatranscriptomic analysis of the 16S rRNA gene. …”
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Metformin Regulating miR-34a Pathway to Inhibit Egr1 in Rat Mesangial Cells Cultured with High Glucose by Can Wu, Ningning Qin, Huiwen Ren, Min Yang, Shuang Liu, Qiuyue Wang

“…And MCs were transfected with small interfering RNA for silencing Egr1 and SIRT1. Quantitative real-time PCR was used to assay the transcription levels of Egr1 mRNA and miR-34a. …”
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Comparative organelle genomics in Daphniphyllaceae reveal phylogenetic position and organelle structure evolution by Rongxiang Zhang, Ying Liu, Shuwen Liu, Yuemei Zhao, Niyan Xiang, Xiaoman Gao, Tao Yuan

“…We also conducted comparative analyses of organelles in Daphniphyllaceae species in terms of genome structure, phylogenetic relationships, divergence times, RNA editing events, and evolutionary rates, etc. …”
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Epac1 Restores Normal Insulin Signaling through a Reduction in Inflammatory Cytokines by Elizabeth Curtiss, Youde Jiang, Li Liu, Claire Hawthorne, Jessica Zhang, Jena J. Steinle

“…Primary human REC were cultured in normal and high glucose followed by Epac1 agonist treatment or transfection with IL-1β or TNFα siRNA for protein analyses of insulin signaling proteins. …”
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The Effects of BMP-2, miR-31, miR-106a, and miR-148a on Osteogenic Differentiation of MSCs Derived from Amnion in Comparison with MSCs Derived from the Bone Marrow by Sirikul Manochantr, Kulisara Marupanthorn, Chairat Tantrawatpan, Pakpoom Kheolamai, Duangrat Tantikanlayaporn, Prakasit Sanguanjit

“…The osteogenic differentiation capacity after miRNA treatment was assessed by ALP expression, ALP activity, and osteogenic marker gene expression. …”
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Tumor-Derived Exosomal miR-29b Reduces Angiogenesis in Pancreatic Cancer by Silencing ROBO1 and SRGAP2 by Lihua Wang, Lei Yang, Tingting Zhuang, Xiuqing Shi

“…Luciferase reporter assays were performed to verify the predicted interaction of miR-29b with ROBO1 and SRGAP2 mRNA. Results. Exosomal miRNA-29b was differentially expressed in the conditioned medium of PC cells. …”
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IONPs-induced neurotoxicity via cascade of neuro-oxidative stress, parthanatos-mediated cell death, neuro-inflammation and neurodegenerative changes: Ameliorating effect of rosemar... by Arwa A. Elsheikh, Noha Ali Abd-Almotaleb, Mona Mostafa Ahmed, Eman El-Sayed Khayal

“…IONPs induced neurotoxicity via triggering a cascade of neuro-oxidative stress, neuro-inflammation, and parthanatos-mediated neuronal cell death by increasing MDA, NO, TNF-α levels, PARP-1, AIF, and NF-κB mRNA expression alongside reducing GSH levels. These incidents contributed to neurodegenerative changes, reflected in increased mRNA expression of α-S, β-APP, and TDP-43. …”
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Induction of Interleukin-8 from Nasal Epithelial Cells during Bacterial Infection: The Role of IL-8 for Neutrophil Recruitment in Chronic Rhinosinusitis by Bit-Na Yoon, Nan-Geum Choi, Hyun-Sun Lee, Kyu-Sup Cho, Hwan-Jung Roh

“…IL-8 concentration and IL-8 mRNA expression continued to increase from 3 hours after incubation in SP number-dependent manner. …”
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Detection of chimeric alpha-defensin transcripts and peptides in mouse Paneth cells by Steven Timmermans, Steven Timmermans, Charlotte Wallaeys, Charlotte Wallaeys, Somara De Beul, Somara De Beul, Natalia Garcia-Gonzales, Natalia Garcia-Gonzales, Claude Libert, Claude Libert

“…IntroductionIn mammals, Paneth cells, located in the crypts of the small intestine, produceantimicrobial peptides that serve to keep the intestinal microbiome under control. a-Defensins are the primary antimicrobial peptides produced by these cells.MethodsWe used 148 publicly available bulk RNA-seq samples on purified PCs, proteomics on enriched purified PC proteins and Defa peptide activity assays to detect all Defa transcrips, including potential chimeric transcrips.ResultsWe identified 28 expressed Defa genes in mice, with up to 85% of Paneth cell RNA reads mapping to these genes. …”
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Effects of Ethyl Pyruvate on Bile Duct Ligation-Induced Liver Fibrosis by Regulating Nrf2 Pathway and Proinflammatory Cytokines in Rats by Yonghua Zong, Mingxiao Zhang, Shuai Li, Wenqian Qi, Juan Li, Tonghua Liu, Huijun Yang, Chen Lu, Xiaosong Hu

“…Furthermore, EP significantly suppressed the mRNA expression levels of HMGB1, IL-1β, TNF-α, and HSP27. …”
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Effects of White Quinoa Polysaccharide on Regulation of Glucolipid Metabolism in Type 2 Diabetic Mice by Yanqing ZANG, Yingying CHUANG, Changyuan WANG, Yang CAO

“…The intestinal contents of the mice were analyzed by 16S rRNA sequencing technology. Results showed that compared with diabetic mice, WQP intake could significantly inhibit the increase of body weight and FBG, improve OGTT, and alleviate insulin resistance in diabetic mice. …”
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PGC1α −1 Nucleosome Position and Splice Variant Expression and Cardiovascular Disease Risk in Overweight and Obese Individuals by Tara M. Henagan, Laura K. Stewart, Laura A. Forney, Lauren M. Sparks, Neil Johannsen, Timothy S. Church

“…PGC1α undergoes splicing to produce several mRNA variants, with the NTPGC1α variant having a similar biological function to the full length PGC1α (FLPGC1α). …”
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Transgenic plants as genetic models for studying functions of plant genes by A. V. Kochetov, V. K. Shumny

“…Genetic constructs for protein synthesis or antisense RNA/self-complementary double-stranded RNA transcription are described. …”
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Effect of Bariatric Weight Loss on the Adipose Lipolytic Transcriptome in Obese Humans by Shakun Karki, Melissa G. Farb, Samantha Myers, Caroline Apovian, Donald T. Hess, Noyan Gokce

“…We performed adipose tissue mRNA expression of proteins involved in triglyceride hydrolysis and correlated their weight loss induced alterations with systemic parameters associated with cardiovascular disease risk. mRNA transcripts of adipose triglyceride lipase (ATGL), hormone-sensitive lipase (HSL), and lipid droplet proteins comparative gene identification 58 (CGI-58) and perilipin increased significantly after weight loss (p<0.05 for all). …”
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Dynamics of REL, RELA and IRF1 transcription factor expression in U937 macrophages after dioxin exposure by E. V. Kashina, D. Y. Oshchepkov, E. V. Antontseva, M. Y. Shamanina, D. P. Furman, V. A. Mordvinov

“…Nuclear extract and total RNA were isolated from U937 macrophages treated with 10 nM TCDD (or 0.1 % DMSO as a control) for 1, 3 and 6 hours. …”
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Endocrine Aspects of 4H Leukodystrophy: A Case Report and Review of the Literature by Emma Billington, Geneviève Bernard, William Gibson, Bernard Corenblum

“…Introduction. 4H leukodystrophy is an autosomal recessive RNA polymerase III-related leukodystrophy, characterized by hypomyelination, with or without hypodontia (or other dental abnormalities) and hypogonadotropic hypogonadism. …”
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