Safety, pharmacokinetics, biomarker response and efficacy of E6742: a dual antagonist of Toll-like receptors 7 and 8, in a first in patient, randomised, double-blind, phase I/II st... by Tomonori Ishii, Yoshiya Tanaka, Atsushi Kumanogoh, Tatsuya Atsumi, Shizuo Akira, Fumitoshi Tago, Mari Aoki, Shintaro Yamamuro

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Cotreatment with methotrexate in routine care patients with rheumatoid arthritis receiving biological treatment yields better outcomes over time by Niels W. Boone, Alexandre Sepriano, Paul-Hugo van der Kuy, Rob Janknegt, Ralph Peeters, Robert B. M. Landewé

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Correction: association between sinusitis and incident rheumatic diseases: a population-based study

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Persistence of power Doppler ultrasonography-detected synovitis over 1 year of follow-up predicts poor prognosis in rheumatoid arthritis in clinical remission: the SONORE prospecti... by Bernard Combe, Nicolas Molinari, Jacques Morel, Gael Mouterde, Cédric Lukas, Nathalie Filippi, Gregory Marin

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The metabolic score for insulin resistance predicts the risk of cardiovascular disease in patients with psoriatic arthritis: results from the 10-year prospective CARMA cohort by Jesús Tornero, Alba Erra, Santos Castañeda, Carolina Pérez-García, Raimon Sanmartí, Sara Marsal, Ingrid Moller, Esperanza Naredo, Miguel A González-Gay, Celia Erausquin, Olaia Fernández, Ivan Castellví, Javier Llorca, Alejandro Muñoz, María Galindo, Enrique Raya, Lydia Abasolo, Gema Bonilla, Alfonso Corrales, Inmaculada Ureña, Carlos Rodríguez-Lozano, Carlos González-Juanatey, Cristina Fernandez Carballido, Eduardo Collantes, José A Miranda-Filloy, Sagrario Bustabad, Indalecio Monteagudo, Jose A Piqueras, Tatiana Cobo, Joan Maymó, Carmen Barbadillo, Soledad Ojeda, Jaime Calvo Alen, Antonio Fernandez Nebro, Isabel Rodríguez, Pilar Font, Martina Steiner, Eugenio Chamizo Carmona, Beatriz González Álvarez, Santiago Munoz, Joan M Nolla, Fernando Sánchez-Alonso, Julio Sanchez, Raul Menor Almagro, Ana Pérez Gómez, Monica Ibañez, Trinidad Pérez Sandoval, Miren Uriarte-Ecenarro, Angela Pecondón, Hye Sang Park, Zulema Plaza, Carmen García Gómez, Ivan Ferraz-Amaro, José L FernándezSueiro, José A Pinto-Tasende, Ramón Huguet Codina, Beatriz Yoldi, Mercedes Ramentol, Gabriela Ávila, Cayetano Alegre, Fernando Gamero, José García Torón, Pilar Espiño, Inmaculada Ros, Horacio Berman, Oscar Fontseré Patón, Benjamín Fernández Gutiérrez, María D Fábregas, Montserrat Romera, María A Belmonte, María V Irigoyen, Olga Martínez González, Rebeca Belmonte Gómez, Pastora Granados Bautista, Azucena Hernández Sanz, José Santos Rey, Javier Bachiller, Antonio Zea, Francisco J Manero, Chesús Beltrán Audera, Marta Medrano, Jesús Babío Herráez, Javier del Pino, Ruth López González, María Enriqueta Peiró, José M Senabre, José C Rosas, Isabel Rotés, Estefanía Moreno, Javier Calvo, Amalia Rueda, Pilar Morales, Ana Nieto, Ana Ruibal Escribano, Carmen García Gómez, Sergio Ros Expósito, Ginés Sánchez Nievas, Enrique Júdez Navarro, Manuela Sianes Fernández, Silvia Martínez Pardo, Manel Pujol, Alberto Cantabrana, Esmeralda Delgado, Sergio Rodríguez Montero, Javier Rivera Redondo, Teresa González Hernández, José M Moreno, Emilio Giner Serret, Laura Cebrián Méndez, María Teresa Navío, Teresa Pedraz Penalva, Encarnación Pagán, Ana Cruz, Ana Turrión, Desireé Ruíz, Antonio López Meseguer, Manuel J Moreno, Luis F Linares, Mercedes Morcillo, José M Aramburu, Natalia A Rivera, Manel Riera, Yolanda María León, Miriam Amirall, Jordi Fiter, Julia Fernández Melón, Luis Espadaler, Joaquín Belzunegui, Inmaculada Bañegil, César Díaz, Ramón Valls, María Bonet, Eva Revuelta Evrard, Javier R Godo, Jose A Pinto Tasende, Eugenia González deRábago, María J GonzálezFernández, María P MorenoGil, Antonio J Mas, José M PinaSalvador, Jesús A GarcíaVadillo, Rosario García deVicuña, Carmen O SánchezGonzález, Francisco J LópezLongo, Francisco J González, Pablo Mesa delCastillo, María L GonzálezGómez, José Antonio GonzálezFernández

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Bridging the gap: facilitating the use of rheumatology research results in clinical practice with hybrid implementation effectiveness studies by Theodora P M Vliet Vlieland, Leti van Bodegom-Vos

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Humoral and cellular SARS-CoV-2 vaccine responses in patients with giant cell arteritis and polymyalgia rheumatica by Elisabeth Brouwer, Kornelis S M van der Geest, Maria Sandovici, Yannick van Sleen, Janneke H Terpstra, Marieke van der Heiden, Debbie van Baarle, Rosanne D Reitsema, Idil Esen, Elisabeth Raveling-Eelsing, Thomas Lieber, Annemarie M Buisman

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Efficacy and safety of upadacitinib in patients with rheumatoid arthritis and inadequate response or intolerance to biological treatments: results through 5 years from the SELECT-B... by Roy Fleischmann, Stephen Hall, Bernard Combe, Andrea Rubbert-Roth, Christina Charles-Schoeman, Nasser Khan, Heidi S Camp, Sebastian Meerwein, Kyle M Carter

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Long-term safety of bimekizumab in adult patients with axial spondyloarthritis or psoriatic arthritis: pooled results from integrated phase IIb/III clinical studies by Robert Landewé, Ana-Maria Orbai, Philip J Mease, Denis Poddubnyy, Lianne S Gensler, Vishvesh Shende, Richard B Warren, Luke Peterson, Alexander Marten, Ute Massow, Katy White, Barbara Ink, Rajan Bajracharya, Myriam Manente

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New blood biomarkers and imaging for disease stratification and monitoring of giant cell arteritis by Christian Dejaco, Alessandro Tomelleri

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Tapering csDMARD or TNFi first: is the risk of flares different for ACPA-positive or ACPA-negative rheumatoid arthritis? by Annette H M van der Helm-van Mil, Pascal H P de Jong, Elise van Mulligen, Agnes E M Looijen, Judith W Heutz

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Using ultrasound to define inflammatory and non-inflammatory phenotypes in difficult-to-treat psoriatic arthritis by Ennio Lubrano, Alen Zabotti, Ivan Giovannini, Luca Quartuccio, Fabio Massimo Perrotta, Andrea Di Matteo, Gabriele De Marco, Dennis McGonagle, Maria De Martino, Miriam Isola, Nicola Cabas, Cristina Di Nicola, Andrea Guiotto, Nicoletta Franzolini

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Holistic approaches in systemic lupus erythematosus: do physicians avoid addressing difficult-to-treat but highly relevant symptoms? by Vibeke Strand, Christopher Sjöwall, Chris Wincup, Ioannis Parodis, Zahi Touma, Jeanette Andersen

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Epidemiology and clinical characteristics of biopsy-confirmed adult-onset IgA vasculitis in southern Sweden by David Jayne, Mårten Segelmark, Aladdin J Mohammad, Karl Gisslander, Michaela Thalen, Jacob Sode

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Outcomes of patients with systemic lupus erythematosus treated with belimumab: a post hoc efficacy analysis of five phase III clinical trials by British Isles Lupus Assessment Grou... by Ronald F van Vollenhoven, Shereen Oon, Mandana Nikpour, Ioannis Parodis, Eric Morand, Adrian Levitsky, Julius Lindblom, Nurşen Çetrez, Leonardo Palazzo, Henri Ala

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Performance of the EULAR Systemic sclerosis Impact of Disease (ScleroID) questionnaire as a patient-reported outcome measure for patients with diffuse systemic sclerosis by Ulf Mueller-Ladner, Marco Matucci-Cerinic, Yannick Allanore, Oliver Distler, Cosimo Bruni, Otylia Kowal-Bielecka, Kim Fligelstone, Roger Hesselstrand, László Czirják, Carina Mihai, Gunnel Sandqvist, Rucsandra Dobrota, Patricia E Carreira, Ana Maria Gherghe, Tore Kvien, Turid Heiberg, Alexandru Garaiman, Mike Oliver Becker, Annelise Roennow, Ann Tyrrell Kennedy, Chris Denton

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Clinical trajectories of hand function impairment in systemic sclerosis: an unmet clinical need across disease subsets by Lorraine Green, Ariane L Herrick, Michelle Wilson, Francesco Del Galdo, Enrico De Lorenzis, Philip Helliwell, Benazir Saleem, Emma Derrett-Smith, Begonya Alcacer-Pitarch, Karen Douglas, Vishal Kakkar, Chris Denton, Theresa Barnes, Stefano Di Donato, Muhammad Nisar, Catherine Morley

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Influence of sacroiliac joint variation on clinical features of axial spondyloarthritis: a comparative analysis by Denis Poddubnyy, Torsten Diekhoff, Sevtap Tugce Ulas, Fabian Proft, Valeria Rios Rodriguez, Judith Rademacher, Juliane Greese, Katharina Ziegeler, Carolina Dominguez Aleixo, Maximilian Lindholz

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Serum biochemical marker of synovial tissue turnover, C1M, predicts radiological progression in early rheumatoid arthritis by Jérémie Sellam, florent Eymard, Patrick Garnero, Roland Chapurlat, Anne-C Bay-Jensen, Sofie Falkenløve Madsen

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Distinct clinical outcomes based on multiple serum cytokine and chemokine profiles rather than autoantibody profiles and ultrasound findings in rheumatoid arthritis: a prospective... by Yukitaka Ueki, Tom W J Huizinga, René E M Toes, Shoichi Fukui, Tomoki Origuchi, Takahiro Maeda, Atsushi Kawakami, Tomohiro Koga, Naoki Matsuoka, Toshihiko Hidaka, Naoki Iwamoto, Mami Tamai, Shin-ya Kawashiri, Akitomo Okada, Ayako Nishino, Tamami Yoshitama, Takahisa Suzuki, Toshimasa Shimizu, Shimpei Morimoto, Tomomi Tsuru, Karin A J van Schie, Masahiro Ayano, Remi Sumiyoshi, Yushiro Endo, Tohru Michitsuji, Kaori Furukawa, Masataka Umeda, Nobutaka Eiraku, Hiroaki Hamada

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