The effect of local anaesthetic agents on opioid use and recovery in patients undergoing open heart surgery: a randomized controlled study by Hatice AZİZOĞLU, Mehmet AŞAM, Zeynep GÜRKAN, Yasemin BOZKURT, Canan DEMİR

“…Conclusions In this study, local anesthetic application to the sternotomy incision site and around the chest tubes after open heart surgery was found to reduce postoperative opioid consumption and positively affect recovery. Trial registration Current Controlled Trials NCT06642077 (Retrospectively registered).…”
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Impact on staff of providing non-invasive advanced respiratory support during the COVID-19 pandemic: a qualitative study in an acute hospital by David Wenzel, Christina Faull, Eleanor Wilson, Lucy Bleazard

“…These protective factors may provide modelling for future education and support services to help prevent moral injury or aide in its recovery.Trial registration number Registered on the Open Science Framework, DOI 10.17605/OSF.IO/TB5QJ…”
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Follow-up care needs and motivational factors for childhood cancer survivors and their parents in Germany by Aleshchenko Ekaterina, Langer Thorsten, Calaminus Gabriele, Glogner Juliane, Hellwig Kathrin, Trocchi Pietro, Swart Enno, Baust Katja

“…Additionally, providing emotional and psychosocial support resources for both survivors and their parents can help address their unique needs at different stages of recovery. Trial registration: Registered at German Clinical Trial Register (ID DRKS00025960 and DRKS00026092).…”
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Efficacy analysis of pancreatic duct stenting in treating severe acute pancreatitis: a retrospective study by Liangping Chen, Ning Wang, Weijie Yao, Chengsi Zhao, Jiahang Tao, Gubai Ma, Chengwang Ma, Zuozheng Wang

“…Pancreatic duct stenting can alleviate symptoms, shorten oral refeeding, and promote patient recovery. Trial registration: This study was recorded as a single-center, retrospective case–control study (ChiCTR1900025833).…”
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Mechanistic insights into PROS1 inhibition of bladder cancer progression and angiogenesis via the AKT/GSK3β/β-catenin pathway by Xin-peng Fan, Ji-rong Wang, Si-yu Chen, Xiao-ran Li, Jin-long Cao, Hua-bin Wang, Li-yun Ding, Tuan-jie Che, Li Yang

“…Next, various functional experiments were performed and the results revealed PROS1 overexpression inhibited the proliferation, cell cycle progression, migration, invasion, and angiogenesis of BLCA. In recovery trials, the AKT activator SC79 offered additional proof that PROS1 may influence BLCA cells via the AKT/GSK3β/β-catenin pathway. …”
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