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25581
A low-protein soybean-free diet improves carcass traits and meat quality and modulates the colonic microbiota in Daweizi pigs
Published 2025-02-01“…Moreover, the purine content in the meat substantially decreased with the LPNS diet. The 16S rDNA analysis revealed that the LPNS diet greatly modified the composition of the colonic microbiota community, with a decrease in the Firmicutes/Bacteroidetes ratio and an increase in the abundance of Lactobacillus spp.DiscussionThe use of functional herbs along with a low-protein diet helped to regulate fat and purine metabolism in fatty-type pigs. …”
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25582
Neoadjuvant chemotherapy combined with antiangiogenic therapy and immune checkpoint inhibitors for the treatment of locally advanced gastric cancer: a real - world retrospective co...
Published 2025-02-01“…All participants underwent surgery, resulting in a notable R0 resection rate of 97.4%. The rates of major pathological response (MPR) and pathological complete response (pCR) were 47.4% and 23.7%, respectively. …”
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25583
The effects of ultra-selective beta1-antagonism on the metabolic and cytokine profile in septic shock patients receiving noradrenaline: a sub-investigation from the STRESS-L Random...
Published 2025-01-01“…Metabolite fingerprinting was carried out by flow infusion electrospray ionisation high-resolution mass spectrometry and metabolomic data were analysed using the R-based platform MetaboAnalyst. The metabolites were identified using DIMEdb (dimedb.ibers.aber.ac.uk) from their mass/charge ratios. …”
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25584
Uridine-cytidine kinase 2 is correlated with immune, DNA damage repair and promotion of cancer stemness in pan-cancer
Published 2025-01-01“…This study aims to shed light on the role and possible mechanism of UCK2 in pan-cancer.MethodsWe used the R programming language for pan-cancer bulk sequencing data analysis, which were obtained from the University of California, Santa Cruz (UCSC) datasets. …”
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25585
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25586
Childhood-Onset Takayasu Arteritis: Clinical Features of Disease and Relapse Risk Factors
Published 2025-01-01“…Clinical, laboratory, and instrumental data were collected and analyzed using R v4.2 and Python v3.10. <b>Results:</b> The median time to relapse was 18 [IQR: 13; -] months according to the Kaplan–Meier curve. …”
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25587
Airway microbiota dysbiosis and metabolic disorder in ozone and PM2.5 co-exposure induced lung inflammatory injury in mice
Published 2025-01-01“…After last exposure, bronchoalveolar lavage fluids (BALF) were collected for inflammatory biomarker measurement, 16S rRNA sequencing and metabolite profiling. Lung tissues were processed for histological examination. …”
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25588
Assessing and Enhancing Nutrition and Physical Activity Environments in Early Childhood Education and Care Centers: Scoping Review of eHealth Tools
Published 2025-01-01“…MethodsThis scoping review adhered to the Joanna Briggs Institute methodology, in accordance with the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews) checklist. …”
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25589
The role of Nazi organizations in German repatriation from the Baltic states (1939-1941)
Published 2006-12-01“…The leaders of Kulturverband, R. Kosmann, K. Cerpinski, O. Reichard, von der Ropp, and E. …”
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25590
Prevalence of dengue and leptospirosis coinfection and associated mortality rates: a systematic review and meta-analysis
Published 2025-01-01“…Statistical analyses, including prevalence and mortality estimation, sensitivity analysis were conducted using R, with heterogeneity evaluated by the I² statistic. …”
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25591
Influence of particle size on NIR spectroscopic characterization of sorghum biomass for the biofuel industry
Published 2025-01-01“…With only 9 selected bands and 4 latent variables (LVs), the best PLSR model was obtained for moisture with particle size of 600–850 µm with the square root of the coefficient of determination (R) of 0.85, the ratio of prediction to deviation (RPD) of 2.2, and the root mean square error (RMSE) of 0.46 % in external validation. …”
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25592
Metasilicate-based alkaline mineral water improves the growth performance of weaned piglets by maintaining gut-liver axis homeostasis through microbiota-mediated secondary bile aci...
Published 2025-03-01“…To analyze the composition of the gut microbiota, 16S rRNA PacBio SMRT Gene Full-Length Sequencing was performed. …”
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25593
Deciphering the therapeutic effects of Xiyanping injection: insights into pulmonary and gut microbiome modulation, SerpinB2/PAI-2 targeting, and alleviation of influenza a virus-in...
Published 2025-01-01“…In this study, we established an IAV infection mice model, and utilized 16 S rRNA sequencing, RNA sequencing, protein chips, and molecular docking, to investigate the mechanisms of XYP injection on altering pulmonary and gut microbiota, and identifying its target sites. …”
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25594
PhantomAR: gamified mixed reality system for alleviating phantom limb pain in upper limb amputees—design, implementation, and clinical usability evaluation
Published 2025-02-01“…Skin temperature in the residual limb increased significantly post-intervention (p < .01) but did not correlate with PLP (r = − 0.08, p = 0.83). Tentacle overlay yielded mixed ownership but high agency ratings. …”
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25595
Ligilactobacillus salivarius LZZAY01 accelerated autophagy and apoptosis in colon cancer cells and improved gut microbiota in CAC mice
Published 2025-02-01“…High-throughput sequencing of gut 16S rRNA was performed to analyze the abundance and diversity of the gut microbiome. …”
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25596
Inhibition of microRNA-139-5p Improves Fibroblasts Viability and Enhances Wound Repair in Diabetic Rats Through AP-1 (c-Fos/c-Jun)
Published 2025-01-01“…Our study further verified that microRNA-139-5p regulated the migration of human skin fibroblasts by modulating c-Fos.Conclusion: Inhibiting microRNA-139-5p improves fibroblasts viability and promotes diabetic wound healing, suggesting that this may be a therapeutic strategy for diabetic foot ulcer. Keywords: miR-139-5p, diabetes, wound healing, AP-1, fibroblasts…”
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25597
TEKNIK MENENTUKAN WAKTU HILANGNYA SYAFAQ (CAHAYA MERAH) MENGGUNAKAN SQY QUALITY METER (SQM) DENGAN METODE TITIK POTONG (CUTOFF)
Published 2021-08-01“…Pengukuran dilakukan dengan menggunakan fotometer portabel, ringan, dan relative murah dengan koneksi USB yaitu Unihedron Sky Quality Meter (SQM). …”
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25598
Lateralized differences in power spectra across different frequency bands during NREM sleep in patients with primary insomnia
Published 2025-01-01“…The Beta1 power was positively correlated the number of awakenings (r = 0.3291, p = 0.02) in primary insomnias on the right side.ConclusionThis study marked the first specialized comparison of power spectral analysis during non-rapid eye movement sleep in different areas and across different frequency bands. …”
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25599
Effects of biologic therapy on novel indices of lung inhomogeneity in patients with severe type-2 high asthma
Published 2025-02-01“…Here, we assessed changes in lung inhomogeneity in patients with type-2 high asthma treated with biological therapy and explored the relationship between inhomogeneity measures and conventional asthma disease markers.Methods This was an observational study of 91 severe type-2 high asthma patients recruited from a tertiary asthma clinic, of whom 67 subsequently started anti-IL5 or anti-IL5R biologics. Patients were evaluated at baseline and, 54 of those commencing biologics, at their fourth injection with either mepolizumab or benralizumab. …”
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25600
New insights into the immunomodulatory potential of sialic acid on monocyte-derived dendritic cells
Published 2024-11-01“…Notably, the lipid-presenting molecules CD1a, CD1b and CD1c remained unaffected by sialidase treatment in MoDCs, a finding also further supported by experiments performed on C1R cells. Inhibition of endogenous sialidases Neu1 and Neu3 during MoDC differentiation did not affect surface MHC-I expression and cytokine secretion. …”
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