PET Study of Sphingosine-1-phosphate Receptor 1 Expression in Response to S. aureus Infection by Hao Jiang, Jiwei Gu, Haiyang Zhao, Sumit Joshi, Joel S. Perlmutter, Robert J. Gropler, Robyn S. Klein, Tammie L. S. Benzinger, Zhude Tu

“…The uptake of [18F]TZ4877 is tightly correlated with the S1R1 expression in response to S. aureus infection. …”
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Effects of Dietary Nano-Composite of Copper and Carbon on Antioxidant Capacity, Immunity, and Cecal Microbiota of Weaned Ira White Rabbits by Ying-Huan Zhou, Xiao-Ping Liu, Xiao-Ming Gu, Hai-Xuan Lv, Yun Yang, Zai-Xing Cai, Bin Di, Chang-Kang Wang, Yu-Yun Gao, Ling Jin

“…In addition, the metagenomic analysis of 16 S rRNA showed significant differences in the cecal microbial structure of weaned Ira white rabbits in the NCCC III group compared with the CON, NCCC I, and NCCC II groups (<i>p</i> < 0.05). …”
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Amniotic fluid microbiota and metabolism with non-syndromic congenital heart defects: a multi-omics analysis by Wenli Xu, Lu Li, Hong Kang, Meixian Wang, Yanqun Liu, Guicun Wang, Ping Yu, Juan Liang, Zhen Liu

“…Methods and results A case-control study was conducted with 17 cases diagnosed with non-syndromic CHDs (CHDs group) and 34 controls without congenital anomalies (control group) at a ratio of 1:2. The 16 S rDNA gene sequencing and metabolomics methods were employed to assess 51 amniotic fluid samples. …”
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Predictive value of MMP-2, MMP-9, TIMP-1 in surgical treatment of localized renal cell cancer by A. I. Tarasenko, A. N. Rossolovskiy, O. L. Berezinets, D. A. Durnov, E. B. Popyhova, V. M. Popkov

“…The study prospectively included medical data of 60 patients with kidney cancer with T1-3N0 M0 who received surgical treatment at the Urology Clinic of the S.R.Mirotvortsev Design Bureau of the SSMU from 2016 to 2019. …”
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Clinical comparison and genetic analysis in pheochromocytoma with primary aldosteronism by Xurong Mai, Mitsuhiro Kometani, Toshiaki Kato, Ko Aiga, Shigehiro Karashima, Daisuke Aono, Seigo Konishi, Koshiro Nishimoto, Kazuyoshi Hosomichi, Atsushi Watanabe, Yuko Noda, Yoshiyu Takeda, Takashi Yoneda

“…In genetic analysis, among the three patients with pheochromocytoma and primary aldosteronism, two had a KCNJ5 (G151R) mutation in the pheochromocytoma tumor tissues. …”
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Organizational readiness and implementation of colorectal cancer screening evidence-based interventions in federally qualified health centers: A cross-sectional study by Emanuelle M. Dias, Timothy J. Walker, Bijal A. Balasubramanian, Paula M. Cuccaro, Lauren Workman, Abraham Wandersman, Maria E. Fernandez

“…Methods: We used data from an ongoing parent study to develop an organizational readiness measure using the R = MC2 heuristic. We conducted descriptive and cross-sectional analyses using FQHC clinic (n = 57) data across three states. …”
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The SPES3 Experimental Facility Design for the IRIS Reactor Simulation by Mario Carelli, Lawrence Conway, Milorad Dzodzo, Andrea Maioli, Luca Oriani, Gary Storrick, Bojan Petrovic, Andrea Achilli, Gustavo Cattadori, Cinzia Congiu, Roberta Ferri, Marco Ricotti, Davide Papini, Fosco Bianchi, Paride Meloni, Stefano Monti, Fabio Berra, Davor Grgic, Graydon Yoder, Alessandro Alemberti

“…Within the framework of an Italian R&D program on Nuclear Fission, managed by ENEA and supported by the Ministry of Economic Development, the SPES3 facility is under design and will be built and operated at SIET laboratories. …”
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Integrated Microbiome and Metabolome Analysis Reveals Correlations Between Gut Microbiota Components and Metabolic Profiles in Mice With Mitoxantrone-Induced Cardiotoxicity by Zhang Q, Liang D, Zhang C, Ye L, Sun P, Zhu H, Zhao Y, Li Y, Guan Y, Zhang H

“…Plasma CK-MB and LDH levels were determined, and the heart tissue histopathology was assessed, followed by utilizing an integrated liquid chromatography-mass spectrometry (LC-MS)-based heart metabolomics study alongside the 16S ribosomal RNA (rRNA) sequencing method to assess MTX impact on GM and CM profiles in mice, establishing associations between GM and CM profiles through the Pearson correlation coefficient calculation.Results: MTX caused CK-MB and LDH level elevations and cardiotoxicity in our mouse model. …”
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A bibliometric analysis of publications in 3D printing in surgery from the web of science database by Bitesh Kumar, Anjan Kumar Dhua, Mohit Garg, Vishesh Jain, Devendra Kumar Yadav, Prabudh Goel, Sachit Anand, Divya Jain

“…A total of 3,230 documents were identified and analyzed using VOSviewer and the Bibliometrix R-package. Inclusion criteria encompassed English-language documents related to 3D printing in surgery, while documents published after December 2022 were excluded. …”
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Spatial and temporal variation of Antarctic microbial interactions: a study around the west Antarctic Peninsula by Swan L. S. Sow, Willem H. van de Poll, Rachel Eveleth, Jeremy J. Rich, Hugh W. Ducklow, Patrick D. Rozema, Catherine M. Luria, Henk Bolhuis, Michael P. Meredith, Linda A. Amaral-Zettler, Julia C. Engelmann

“…Results We report on the seasonal diversity, taxonomic overview, as well as predicted inter-and intra-domain causal effects (interactions) of the bacterial and microbial eukaryotic communities close to the Palmer station and at the Rothera time-series site between July 2013 and April 2014. Our 16S- and 18S-rRNA gene amplicon sequencing data showed that across all seasons, both bacteria and microbial eukaryotic communities were considerably different between the two sites which could be attributed to seawater temperature, and sea ice coverage in combination with sea ice type differences. …”
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Chemical cross‐linking facilitates antigen uptake and presentation and provides improved protection from Mpox with a dual‐antigen subunit vaccine by Long Chen, Chao Shang, Zihao Wang, Mengzhu Zheng, Cuiling Zhang, Dapeng Li, Zhanqun Yang, Yuchao Dong, Yuru Xu, Yunsheng Yuan, Shiyong Fan, Wu Zhong, Jian Lin, Xiao Li

“…We applied this strategy to monkeypox virus antigens A29L and A35R to construct dual‐antigen subunit vaccines. Our results revealed that chemical cross‐linking was robust enough to improve both proteins' APC uptake and lymph node accumulation, with each protein being chemically cross‐linked and administered separately. …”
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Ginkgo biloba Extract Improves Insulin Signaling and Attenuates Inflammation in Retroperitoneal Adipose Tissue Depot of Obese Rats by Bruna Kelly Sousa Hirata, Renata Mancini Banin, Ana Paula Segantine Dornellas, Iracema Senna de Andrade, Juliane Costa Silva Zemdegs, Luciana Chagas Caperuto, Lila Missae Oyama, Eliane Beraldi Ribeiro, Monica Marques Telles

“…In addition, a significant increase of both Adipo R1 and IL-10 gene expressions and IR and Akt phosphorylation was also observed, while NF-κB p65 phosphorylation and TNF-α levels were significantly reduced. …”
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Incidence of Malignancies and the Association with Biological Disease-Modifying Antirheumatic Drugs in Japanese Patients with Rheumatoid Arthritis: A Time-Dependent Analysis from t... by Masayoshi Harigai, Eiichi Tanaka, Eisuke Inoue, Ryoko Sakai, Naohiro Sugitani, Shigeyuki Toyoizumi, Naonobu Sugiyama, Hisashi Yamanaka

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Divergent response to radio-immunotherapy is defined by intrinsic features of the tumor microenvironment by Christian Klein, Maria Amann, Jacob Gadwa, Laurel B Darragh, Miles Piper, Diemmy Nguyen, Sana D Karam, Michael W Knitz, Justin Yu, Nicholas Olimpo, Sophia Corbo, Jessica I Beynor, Brooke Neupert, Alexander T Nguyen, Chloe Hodgson, Khalid NM Abdelazeem, Anthony Saviola, Laurene Pousse, Ali Bransi, Mudita Pincha

“…However, to date there are few preclinical models that accurately represent these disparate disease scenarios.Methods Using combinatorial radio-immunotherapy consisting of PD-1 blockade, IL2Rβγ biased signaling, and OX40 agonism we were able to generate preclinical tumor models with conflicting responses, where head and neck squamous cell carcinoma (HNSCC) models respond and pancreatic ductal adenocarcinoma (PDAC) progresses.Results By modeling these disparate states, we find that regulatory T cells (Tregs) are expanded in PDAC tumors undergoing treatment, constraining tumor reactive CD8 T cell activity. …”
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Expanded screening for Fabry disease in patients with chronic kidney disease not on dialysis: a multicenter Italian experience by Yuri Battaglia, Federica Baciga, Meilad Shakkour, Savio Russo, Giulia Carnicella, Michela Erlati, Gemma Sartori, Giulia Tronconi, Renzo Mignani, Federico Pieruzzi, Paolo Colomba, Laura Scichilone, Michele Andreucci, Concetto Sessa, Giovanni Duro

“…One patient with three family members carrying a novel mutation (c.320 A > G, p.Q107R); one patient with three family members carrying a silent mutation (c.48 T > G, p.L16L) and two patients with a missense mutation (c.376A > G, p.S126G), were identified. …”
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Toxic Effects of Hydroxyl- and Amine-functionalized Silica Nanoparticles (SiO2 and NH2-SiO2 NPs) on Caenorhabditis elegans by Danielle E. Que, Wen-Che Hou, Micah Belle Marie Yap Ang, Chih-Chung Lin

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Facial Anthropometry and Self-expressed Behaviours: A Systematic Review by Ankit Srivastava, Vilas Chimurkar, Nisha Mani Pandey, Anand Bihari

“…The overall coefficient across all studies was r=0.37, 95% Confidence Interval (CI) (0.27, 0.47), p <0.01, indicating a moderate positive correlation. …”
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Comparing Optimal Portfolio Performance Based on Skew-Normal Distribution and Skew-Laplace-Normal Distribution: A Mean-Absolute Deviation-Entropy Approach by Hila Rezaei, Gholamhossien Golarzi, Omid Karimi

“…After fitting density functions for Skew-Normal and Skew-Laplace-Normal distributions to the returns, maximum likelihood estimates were obtained using the Stats package and the optim Function in R software. The reliability of these estimates was then checked using bootstrap sampling with 1,000 repetitions. …”
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Efecto de programa de ejercicios físicos para la fuerza de extremidades inferiores en adultos mayores by Jorge Luis Abreus Mora, Vivian Bárbara González Curbelo, Fernando Jesús del Sol Santiago, Ovel Mena Pérez, Jorge Andrés Abreus Vázquez, Ernesto Julio Bernal Valladares.

“…Estadísticamente, se realizó un análisis descriptivo de datos y comparación, según la distribución de frecuencias y porcentajes de indicadores de fuerza; se determinó correlación e independencia entre variables: fuerza, sexo, edad y padecimientos, mediante los estadísticos de correlación Chi-cuadrado de Pearson, R de Pearson y Correlación de Spearman. Se aplicó Chi-cuadrado de Pearson, Gamma y Tau-b de Kendall, con normalidad en la distribución de los datos y confianza p=0,05, por medio del programa estadístico IBM SPSS para Windows versión 21.0.…”
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Farm factors associated with increased free fatty acids in bulk tank milk by Hannah M. Woodhouse, Stephen J. LeBlanc, Trevor J. DeVries, Karen J. Hand, David F. Kelton

“…The final model adjusted R2 of 29% indicates that more factors associated with bulk tank milk FFA still need to be identified, which may include seasonal, milk composition, and individual cow factors.…”
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