The role of natural exosomes from SHED-MSC in immunoregulation of M0/M1 polarized macrophage cells by Ali Fallah, Abasalt Hosseinzadeh Colagar, Ayyoob Khosravi, Ayyoob Khosravi, Azadeh Mohammad-Hasani, Azadeh Mohammad-Hasani, Mohsen Saeidi, Mohsen Saeidi

“…In contrast, there was a reduction in pro-inflammatory and pro-oxidant markers, including CD80, CD81, IL-6R, IL-12, TNF-α, MDA, and NO, which act as immunostimulatory macromolecules (P < 0.05).DiscussionThe findings suggest that exosomes derived from SHED-MSC can skew M0/M1 macrophages to the M2 phenotype and inhibit M1 polarization. …”
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The Effectiveness of Rapamycin Combined with Eltrombopag in Murine Models of Immune-Mediated Bone Marrow Failure by Shaoxue Ding, Xiaowei Liang, Tian Zhang, Rong Fu

“…We did not observe the difference in the curative effect of the Rapa group and CsA group, but for IL-10/Tregs ratio, the Rapa group was superior to the CsA group. And the IFN-r secretion of CD8+T cells in AA mice decreased significantly after the combination therapy of Rapa and Elt than Rapa alone. …”
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پتانسیل سنجی شبکه‌های باور بیزین در برآورد و ارزیابی میزان فرسایش بادی (منطقه مورد مطالعه: دشت دهلران- ایلام)... by علی محمدیان بهبهانی, عبدالحسین بوعلی

“…ضریب تبیین بین خروجی معیار فرسایش بادی مدل  IMDPA و BBN نشان داد که نتایج حاصل از هر دو مدل دارای همبستگی معنی‌دار(R2> 0.60, p ˂ 0.05)  می‌باشد. این مطالعه نشان داد که ارائه مدل فرسایش بادی به شکل شبکه باور بیزین می‌تواند بررسی نتایج سناریوهای مختلف را تسهیل نموده و عدم قطعیت حاصل از ارتباطات متغیرها را نمایش دهد.…”
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Prediction model for unfavorable treatment outcome for complicated sever acute malnutrition (SAM) in under five children admitted in hospitals at Amhara Region by Almaw Genet Yeshiwas, Zelalem Alamrew Anteneh, Tilahun Degu Tsega, Ahmed Fentaw Ahmed, Chalachew Yenew

“…Data analysis was conducted using STATA 17 and R 4.4.1. A lasso-selected multivariable model developed a nomogram for clinical utility. …”
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Simultaneous Determination of Multiple Active Components from Bushen Pills and Application in a Pharmacokinetic Study in Rats by Houli Li, Benjie Wang, Guiyan Yuan, Xiaoyan Liu, Jing Huang, Lilong Xiong, Di Zhang, Weiyi Feng, Ruichen Guo

“…The linear ranges of PF and BBR were 5–500 ng/mL and 0.1–20 ng/mL with good linearity (r2 > 0.99). No obvious matrix effect was observed, and acceptable accuracy, precision, recovery, and stability were obtained. …”
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Photosynthetic Pigments with Potential for a Photosynthetic Antenna: A DFT Analysis by Jesús Francisco Monzón-Bensojo, Manuel A. Flores-Hidalgo, Diana Barraza-Jiménez

“…The evaluated electronic properties at the gas phase included (a) energies such as HOMO-LUMO band gap (H-L, ranging from 2.168 to 2.504 eV), adiabatic ionization potential (I, ranging from 5.964 to 7.207 eV), and adiabatic electronic affinity (A, ranging from 2.176 to 2.741 eV); (b) global chemical reactivity indexes such as electronegativity (χ, ranging from 4.121 to 4.974 eV), hardness (η, ranging from 1.812 to 2.233 eV), electrophilicity index (ω, ranging from 4.365 to 5.541 eV), and electroaccepting-electrodonating powers (ω+, ranging from 1.671 to 2.115 eV, and ω−, ranging from 4.375 to 5.273 eV); (c) electron-hole reorganization energies (λ, ranging from 0.225 to 0.519 eV and ranging from 0.168 to 0.425 eV, respectively) and electron-hole extraction potentials (EEP, ranging from 2.570 to 2.966 eV, and HEP, ranging from 5.538 to 7.012 eV, respectively); and (d) local chemical reactivity indexes like condensed Fukui functions (fk), condensed dual descriptor (f2r), and condensed local softness (sk). These electronic properties allowed the association between molecules and reactivity-selectivity criteria, under the context of charge transfer and electronic transitions. …”
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Impact of gate metals/high-K materials and lateral scaling on the performance of AlN/GaN/AlGaN-MOSHEMT on SiC wafer for future microwave power amplifiers in RADAR & communicati... by Gauri Deshpande, J. Ajayan, Sandip Bhattacharya, B. Mounika, Amit Krishna Dwivedi, D. Nirmal

“…The impact of high-K dielectric materials (HfO2: K = 25, ZrO2: K = 30 and TiO2: K = 80), oxide thickness (tox), gate metals (Al: ϕm=4.3 eV, Ti: ϕm=4.33 eV, Mo: ϕm=4.6 eV, Au: ϕm=5.1 eV, Ni: ϕm = 5.15 eV, Ir: ϕm = 5.27 eV & Pt: ϕm = 5.65 eV) and lateral scaling effects (LGS: Source (S) to Gate (G) distance & LGD: Drain (D) to Gate distance) on the DC & RF behaviour of LG = 100 nm (gate length) GaN-channel MOSHEMT featuring R-Gate, AlGaN-back barrier and AlN barrier is investigated at 300 K using TCAD tool. …”
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Necesidad de estimar el filtrado glomerular para valorar la función renal by José Antonio Chipi Cabrera, Miguel Almaguer López, Raúl Herrera Valdés, Julio Alexander Silveira Echavarría, Miriam de la Caridad Abreu Correa, Odeime Fariñas Martínez

“…El coeficiente de correlación entre los valores de creatinina plasmática y el filtrado glomerular para cada fórmula expresa una relación lineal con r [0,639 fórmula de C-G (p = 0,000)]; [0,672 MDRD-4 (p = 0,000)] y [0,939 fórmula CKD-Epi (p = 0,000)]. …”
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An Enhanced Three-Band Algorithm for Retrieving Phycocyanin Concentration from Satellite Data in Plateau Inland Lake by Dajun Yuan, Bo-Hui Tang, Dong Wang, Junyi Chen, Zhen Zhang, Zhitao Fu

“…Among all the phycocyanin (PC) algorithms considered in this study, the Enhanced Three Band Algorithm (ETBA) achieved the lowest mean relative error (12.76&#x0025;) and a goodness of fit of (<italic>R</italic>² &#x003D; 0.73), with the second lowest root mean square error of 0.37 &#x03BC;g/L. …”
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Phylogenetic and Comparative Genomics Study of <i>Cephalopina titillator</i> Based on Mitochondrial Genomes by Huaibing Yao, Wanpeng Ma, Zhanqiang Su, Yuanyuan Yan, Yang Li, Weidong Cui, Jie Yang, Faqiang Zhan, Min Hou

“…Herein, <i>C. titillator</i> was isolated from the Junggar Bactrian camel to assemble a complete circular mitogenome with a length of 16,552 bp encoding 13 protein-coding genes, 22 tRNA genes, and two rRNA genes. The mitogenome showed a high A + T content (73.31%), positive AT-skew (0.12), and negative GC-skew (−0.34) base composition patterns. …”
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Nephropathy in Hypertensive Animals Is Linked to M2 Macrophages and Increased Expression of the YM1/Chi3l3 Protein by Paula Andréa Malveira Cavalcante, Natalia Alenina, Alexandre Budu, Leandro Ceotto Freitas-Lima, Thaís Alves-Silva, Juan Sebastian Henao Agudelo, Fatimunnisa Qadri, Niels Olsen Saraiva Camara, Michael Bader, Ronaldo Carvalho Araújo

“…Bone marrow cells were isolated from the femurs and tibia of male FVB/N (control) and transgenic hypertensive animals that overexpressed the rat form of angiotensinogen (TGM(rAOGEN)123, TGM123-FVB/N). The cells were treated with murine M-CSF and subsequently with LPS+IFN-γ to promote their polarization into M1 macrophages and IL-4+IL-13 to trigger the M2 phenotype. …”
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Single-Cell RNA-Seq Uncovers Cellular Heterogeneity from Deep Fascia in Necrotizing Fasciitis Patients by Wang T, Zhang L, Chen W, Long Y, Zhang Y, Wang L, Hou Z

“…Tao Wang,1,&ast; Liping Zhang,2,&ast; Wei Chen,3 Yubin Long,3 Yingze Zhang,3– 6 Ling Wang,3 Zhiyong Hou3– 6 1Department of Lower Limb Trauma, Beijing Jishuitan Hospital, Guizhou Hospital, Guiyang, Guizhou, People’s Republic of China; 2Department of Physiology, Hebei Medical University, Shijiazhuang, Hebei, People’s Republic of China; 3Department of Orthopaedic Surgery, Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, People’s Republic of China; 4Engineering Research Center of Orthopedic Minimally Invasive Intelligent Equipment, Ministry of Education, Shanghai, People’s Republic of China; 5Key Laboratory of Biomechanics of Hebei Province, Shijiazhuang, Hebei, People’s Republic of China; 6NHC Key Laboratory of Intelligent Orthopaedic Equipment, Shijiazhuang, Hebei, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Zhiyong Hou, Department of Orthopaedic Surgery, Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, P.R. China. No. 139 Road Ziqiang, Shijiazhuang, Hebei, People’s Republic of China, Email drzyhou@gmail.comPurpose: Necrotizing fasciitis (NF) is a scarce but potentially life-threatening infection. …”
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Microbial keratitis in Southern Malawi: a microbiological pilot study by Timothy Neal, Dean Everett, Stephen B Kaye, Alistair Darby, Moira Gandiwa, Shaffi Mdala, Caroline E Corless, Rose Herbert, Nicholas A V Beare, Tobi F Somerville, Thokozani Zungu, Malcolm J Horsburgh, Petros C Kayange

“…Samples were processed using culture and PCR for Acanthamoeba, herpes simplex virus type 1 (HSV-1) and the bacterial 16S rRNA gene. Minimum inhibitory concentrations of isolates to eight antimicrobials were measured using susceptibility strips. …”
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Evaluation of Theileria equi vertical transmission rate and routes in a cohort of asymptomatic mares and their foals by Lisa-Marie Hermans, Claire Bonsergent, Anne Josson, Gloria Rocafort-Ferrer, Marine Le Guyader, Sophie Angelloz-Pessey, Agnès Leblond, Laurence Malandrin

“…One foal was born carrier but T. equi DNA had not been detected in the placenta. The 18S rRNA genotype E of T. equi was characterized in the four foals, foetal parts of the placenta and colostrum. …”
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Assessment of the sedimentation and trapping efficiency in dam reservoirs by applying the settling basin framework by Bérenger Koffi, Koffi Eugène Kouakou, Alexis Loukou Brou, Martin Sanchez, Ouédé Gla Blaise, Brice Wawogninlin Coulibaly, Franck Hervé Akaffou, Michal Habel, Amani Michel Kouassi, Dibi Brou, Kouakou Lazare Kouassi

“…New hydrological insights for the region: The analysis shows that the reservoir's trapping capacity is influenced by settling velocity, critical velocity, shape parameter 1/r, and the Peclet number (Pe). The study found strong synchronization between models for constant settling velocity (CV-NT, CV-CM, CV-Teeter (1986)) and variable settling velocity (VV-NT, VV-CM) with Teeter’s (1986) model. …”
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بررسی دامنه شبانه‌روزی دما در ایران با استفاده از مجموعه داده AgERA5 by سیده فاطمه اخلاقی حسینی, آذر زرین, عباسعلی داداشی رودباری

“…جهت درستی­سنجی مجموعه داده AgERA5 از داده­های 56 ایستگاه هواشناسی همدید و سنجه­های آماری RMSE و R2 و برای بررسی متوسط روند از آزمون Theil-Sen استفاده گردید. …”
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Dinámica morfométrica de las lagunas de los valles transversales de la provincia de La Pampa como respuesta a eventos extremos de inundación y sequía by Contreras Felix Ignacio, Valeria Soledad Duval

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Structural reversal of disc cupping measured in Bruch’s membrane opening-based OCT morphometry after PRESERFLO microshunt implantation for open-angle glaucoma by Jan Niklas Lüke, Constantin Popp, Caroline Gietzelt, Florian Steinberg, Vincent Lüke, Alexandra Lappa, Thomas Dietlein, Philip Enders

“…A decrease in IOP correlated significantly with a change in BMO-MRW (r = 0.453, p < 0.05) three months after surgery. …”
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CSGD-YOLO: A Corn Seed Germination Status Detection Model Based on YOLOv8n by Wenbin Sun, Meihan Xu, Kang Xu, Dongquan Chen, Jianhua Wang, Ranbing Yang, Quanquan Chen, Songmei Yang

“…The detection precision(<i>P</i>), recall(<i>R</i>), mAP_0.5, and mAP_0.50:0.95 achieved are 89.44%, 88.82%, 92.99%, and 80.38%. …”
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Biochemical Pattern of Methylmalonyl-CoA Epimerase Deficiency Identified in Newborn Screening: A Case Report by Evelina Maines, Roberto Franceschi, Francesca Rivieri, Giovanni Piccoli, Björn Schulte, Jessica Hoffmann, Andrea Bordugo, Giulia Rodella, Francesca Teofoli, Monica Vincenzi, Massimo Soffiati, Marta Camilot

“…The analysis of methylmalonic pathway genes by next-generation sequencing (NGS) allowed the identification of the known homozygous nonsense variation c.139C>T (p.R47X) in exon 2 of the MCE gene. Conclusions: Elevated concentrations of C3 with a slight increase in MCA and normal MMA and Hcy during NBS should prompt the consideration of MCEE deficiency in differential diagnosis. …”
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