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24921
Predictive value of dendritic cell-related genes for prognosis and immunotherapy response in lung adenocarcinoma
Published 2025-01-01“…Performance of the prognostic model, DCRGS, for the prognostic evaluation, was assessed using a multiple time-dependent receiver operating characteristic (ROC) curve, the R package, “timeROC”, and validated using GEO datasets. …”
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24922
Sorafenib enhanced the function of myeloid-derived suppressor cells in hepatocellular carcinoma by facilitating PPARα-mediated fatty acid oxidation
Published 2025-01-01“…Mechanistically, sorafenib significantly inhibited the differentiation of macrophages by upregulating PPARα expression and suppressing the PU.1-CSF1R pathway. Conclusion Overall, our study demonstrated that sorafenib enhanced the function of MDSCs by facilitating PPARα-mediated FAO and further augmenting sorafenib resistance, which sheds light on dietary management and improves the therapeutic response in HCC.…”
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24923
Development and validation of a LAMP-based method for rapid and reliable detection of Xanthomonas albilineans, the causal agent of sugarcane leaf scald
Published 2025-01-01“…Sugarcane samples from infected plants were subjected to heat lysis, followed by loop-mediated isothermal amplification (LAMP)-based fluorescence and colorimetric quantification within a single microcentrifuge tube.ResultsThe method exhibited exceptional detection sensitivity (detecting as low as 1 cell/μL), reproducibility [with a standard deviation (SD) of <5% for n = 3], and a broad linear dynamic range (10 pM to 1 aM or 107–100 copies/μL, r = 0.99). Quantification of Xalb was accurately correlated with sugarcane cultivar disease ratings. …”
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24924
Reduced Presence of SARS-CoV-2 microRNA-like Small RNA in the Serum of Patients with Post-Acute Sequelae SARS-CoV-2 Infection
Published 2025-01-01“…Initially, it was demonstrated that three previously identified SARS-CoV-2 miRNA-like small RNAs, specifically svRNA 1 and 2 and miR-07a, were significantly expressed in infected cells in vitro and released into the supernatant following infection by different SARS-CoV-2 variants. …”
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24925
Sex-biased prevalence in infections with heterosexual, direct, and vector-mediated transmission: a theoretical analysis
Published 2018-01-01“…It is also shown that the ratio of attack ratios depends solely on the ratio of gender-specific susceptibilities and on the basic reproductive number of the epidemic $ \mathcal{R}_0 $, and that the gender-specific final attack-ratio is biased in the same direction as the gender-specific susceptibilities. …”
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24926
Curing modes affects micro-tensile bond strength and durability of dual curing resin cements to dentin
Published 2025-01-01“…The 6 dual-cured resin cements were: DU (Duolink, Bisco), TC (TheraCem, Bisco), MS (Multilink Speed, Ivoclar), N3 (Nexus 3 Universal, Kerr), R2 (RelyX U200, 3M) and RU (RelyX Ultimate, 3M). …”
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24927
Unveiling the UNESCO Biosphere Reserve of the Berlengas Archipelago in Portugal as a Hotspot of Fish Species Using eDNA Metabarcoding and the Collaboration of Fishing Crews
Published 2025-01-01“…This study aims to evaluate the spatiotemporal diversity of fish using 12S rRNA gene eDNA metabarcoding sequencing in the Berlengas archipelago and compare two seawater eDNA sampling sources: samples collected by fishermen during their activities and those collected by our research team. …”
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24928
Theoretical study of the Sb-substitution effect on the optoelectronic properties of Cs2AgBiBr6 double perovskite
Published 2025-01-01“…Furthermore, we assessed multiple optical properties including reflectivity (R), absorption coefficient (α), refractive index (n*), dielectric function (ε), optical conductivity (σ), and loss function L(ω). …”
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24929
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24930
Chicken C4BPM facilitates replication of H5N1 and H9N2 Avian Influenza Viruses by inhibiting the production of type I interferons
Published 2025-03-01“…Replication of H5N1 and H9N2 AIVs were promoted in C4BPM-overexpressing DF-1 cells with inhibited expression of type I IFNs (IFN-α, IFN-β), protein kinase R (PKR), cholesterol 25-hydroxylase (CH25H), interferon regulatory factor (IRF) 3, and mitochondrial antiviral signaling protein (MAVS) compared to that of the DF-1 cells. …”
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24931
Land surface temperature changes caused by land cover/land use properties and their impact on rainfall characteristics
Published 2023-07-01“…For the relationship between the built-up index and land surface temperature, the results of the analysis show that both have a directly proportional relationship, with a significant coefficient of determination (R2>0.5). For the relationship between land surface temperature and rainfall characteristics, the results of the analysis show that land surface temperature has a directly proportional but weak relationship with rainfall intensity and an inversely proportional but weak relationship with the number of rainfall days. …”
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24932
Role of Aging in Ulcerative Colitis Pathogenesis: A Focus on ETS1 as a Promising Biomarker
Published 2025-02-01“…A series of machine learning algorithms was used to screen two feature genes (ETS1 and IL7R) to establish the diagnostic model, which exhibited satisfactory diagnostic efficiency. …”
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24933
Ultrasonic-assisted adsorption of methylene blue using shrimp shells as a low-cost adsorbent: Evaluation on the adsorption isotherm, kinetics, and thermodynamics
Published 2025-04-01“…The adsorption kinetics study revealed that the experimental data for all three adsorbents conformed well to the Pseudo-Second Order model, with R2 values ranging from 0.99998 to 1.0000. Finally, the thermodynamic assessment demonstrated that ultrasonic-assisted MB adsorption with the three adsorbents was spontaneous, with ΔG° values of -1,542, -10,669, and -10,680 kJ/mol, ΔS° values of 62.845, 150.900, and 162.260 kJ/mol.K, and ΔH° values of 17,347, 35,088, and 38,339 kJ/mol for A1, A2, and A3, respectively.…”
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24934
Exploring the Social Media Discussion of Breast Cancer Treatment Choices: Quantitative Natural Language Processing Study
Published 2025-01-01“…MethodsReddit posts and comments from the Reddit subreddit r/breastcancer and associated metadata were collected using pushshift.io. …”
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24935
An Automatic Decision-Level Fusion Rice Mapping Method of Optical and SAR Images Based on Cloud Coverage
Published 2025-01-01“…The results obtained by the Auto-OSDF method show an average R<sup>2</sup> of 0.926 compared to municipal-level statistical planting areas. …”
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24936
Acupuncture combined with multiple therapies for angina pectoris: a systematic review and network meta-analysis
Published 2025-01-01“…A random-effects Bayesian NMA was performed using R (version 4.3.1) and Stata (version 16.0).Results46 RCTs were enrolled, with 3976 patients with angina pectoris. …”
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24937
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24938
The correlations between demographic factors, self-efficacy, and quality of life among Indonesian patients with ischemic stroke: A cross-sectional study
Published 2025-01-01“…There was a significant positive correlation between self-efficacy and quality of life (r = 0.898, p <0.001). Conclusion: The results of this study provide valuable insights for nursing practice, emphasizing the importance of interventions to enhance patients’ self-efficacy. …”
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24939
Phylogeography and genetic diversity of Ulmus elongata (Ulmaceae), a Tertiary relict tree with extremely small populations (PSESP)
Published 2025-01-01“…The Mantel tests indicated a significant correlation between genetic differentiation and geographical distances (r = 0.3777, p < 0.05) in U. elongata populations. …”
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24940
Respuesta lacustre a la variabilidad climática en los valles transversales (La Pampa, Argentina)
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