The efficacy of an allosteric modulator of the alpha 7 nicotinic acetylcholine receptor in a murine model of stroke by Katherine Hernandez, Nathan Jones, Sterling B. Ortega

“…Using a murine transient middle cerebral artery occlusion (tMCAO) model, we sought to evaluate the neurotherapeutic efficacy of a positive allosteric modulator of the alpha7 nicotinic acetylcholine receptor (α7-nAChR), PNU-120596 (PNU), specifically examining whether PNU would modulate stroke-induced neurological dysfunction and neuropathology, with modulation of neuroinflammation as a possible mechanism.MethodsYoung male C57BL/6J mice received a subcutaneous injection of 20mg/kg of vehicle (DMSO) or PNU-120596 immediately after reperfusion, and infarct area and Bederson score were analyzed 24 hours post-stroke. …”
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Synthesis of Specific ZnF Based Nanoparticles (ZnFe2O4): Antimicrobial Properties, Surface Characteristics, and Adsorption Activity for AB 29 Textile Dye by Ferda Gönen, Gökhan Tekinerdoğan

“…Langmuir and especially Freundlich linear isotherm models provided the highest R2 regression coefficients, successfully. The kinetic data was evaluated by pseudo-first-order and pseudo-second-order kinetic model approach. …”
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Analytical Review of Digital Accessibility Services on Official Sites of the World’s Best Universities by E. A. Kosova

“…It seems important to create similar web resources and corresponding structural subdivisions in universities of the Russian Federation, as well as to approve the intra-university local acts regulating the mandatory fulfillment of digital accessibility requirements in the development of educational content and the procurement of digital products and services. GOST R 52872-2019, based on WCAG 2.1, should be used as the basis for local legal regulations.…”
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Advancing forensic investigations based on TiO2/Bi2O3 electrochemical sensor for precise potassium estimation in vitreous humor by Zulfiqar Ali Buzdar, Hamza Ali, Maria Munir, Naveed A. Shad, Allah Rakha, Anam Munawar

“…Through rigorous analysis, we establish a robust linear correlation (R2 = 0.992) between the nanocomposite and potassium concentrations in postmortem vitreous samples. …”
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Predictive modelling of hexagonal boron nitride nanosheets yield through machine and deep learning: An ultrasonic exfoliation parametric evaluation by Jerrin Joy Varughese, Sreekanth M․S․

“…The DNN with the Adam optimizer achieved the highest accuracy (R² = 0.98423), demonstrating superior predictive capability compared to other ML and DL models. …”
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Three-Dimensional Reconstruction of Space Targets Utilizing Joint Optical-and-ISAR Co-Location Observation by Wanting Zhou, Lei Liu, Rongzhen Du, Ze Wang, Ronghua Shang, Feng Zhou

“…Experimental results verify the effectiveness and robustness of the OC-V3R-OI method.…”
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Validity and Reliability of Hospitalization Anxiety Scale Based on Parent Perception in Children Age 1-6 Years by Hermalinda Herman, Apiradee Pimsen, Lili Faria, Deswita, Okky Adelirandy, Rahmatika Amelda, Rahmi Ramadhan

“…The results showed that 15 items were valid and reliable (r > 0.339) and Cronbach's Alpha value = 0.885). …”
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Impact of Extracellular Matrix-Related Genes on the Tumor Microenvironment and Prognostic Indicators in Esophageal Cancer: A Comprehensive Analytical Study by Yinghong Wu, Wenjie Hu, Zhihong Jia, Qiying Zhu, Jinghui Xu, Liang Peng, Renjie Wang

“…Our study utilized next-generation sequencing and clinical data from esophageal cancer patients provided by The Cancer Genome Atlas, employing the R package in RStudio for computational analysis. …”
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Fast Determination of the Main Reduced Sulfur Species in Aquatic Systems by a Direct and Second-Derivative Spectrophotometric Method by Sébastien Dupraz, Bénédicte Ménez, François Guyot

“…The method displays low accuracy mean and low relative standard deviation (<4%) as well as a good linearity (R2 > 0.999). Accordingly, this method represents a very robust alternative in terms of cost and rapidity for the quantification of reduced sulfur species in different aquatic environments, from freshwaters to saline and polluted systems.…”
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Comparison of OnBaseU Tests with Biomechanical Motion Analysis in Youth Baseball Pitchers by Tessa Hulburt, Taylor Catalano, Kristen F. Nicholson

“…Further, OnBaseU and motion capture seated trunk rotation tests were not correlated (r = 0.003) and not found to be statistically associated (p = 0.83)…”
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Phylogeny of Flavobacteria Group Isolated from Freshwater Using Multilocus Sequencing Analysis by Seyoung Mun, Jungnam Lee, Siwon Lee, Kyudong Han, Tae-Young Ahn

“…Sequence analysis of the 16S rRNA gene has been widely used for the classification of microorganisms. …”
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Growth and Feeding Ecology of Dnieper chub Petroleuciscus borysthenicus (Kessler, 1859) in Şahinkaya Reservoir, an Artificial Water Body of an Island Ecosystem (Gökçeada, Turkey)... by Gülşah Saç, Sevan Ağdamar

“…LWR and K values were estimated for all specimens as W=0.017×SL3.114 (r=0.988) and 2.04 (±0.28), respectively. F:M sex ratio was calculated as 1:1.33 with no signifi-cant difference from the ratio of 1:1 (2=0.02; p&gt;0.05). …”
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Validation of an Individualized Measure of Quality of Life, Patient Generated Index, for Use with People with Parkinson’s Disease by Ayse Kuspinar, Kedar K. V. Mate, Anne-Louise Lafontaine, Nancy Mayo

“…The PGI was moderately correlated (r = −0.35) with the standardized disease-specific QOL measure Parkinson’s Disease Questionnaire (PDQ-8). …”
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Comparative chemical investigation and evaluation of antioxidant and tyrosinase inhibitory effects of Withania somnifera (L.) Dunal and Solanum nigrum (L.) berries by Hameed Abdul, Akhtar Naveed

“…Total flavonoids and total phenolics were quantified in WSEA (96.91 ± 1.56 μg QE mg-1 sample and 178.45 ± 2.78 μg GAE mg-1 s ample, r esp.) and S NEA (89.58 ± 0.98 μg QE mg-1 sample and 120.15 ± 2.33 μg GAE mg-1 sample, resp.). …”
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Efficacy and tolerance of second-generation antipsychotics in anorexia nervosa: A systematic scoping review. by Solène Thorey, Corinne Blanchet, Sélim Benjamin Guessoum, Marie Rose Moro, Maude Ludot, Emilie Carretier

“…This work complies with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis extension for scoping reviews (PRIMA-ScR) and was registered in the Open Science Framework (OSF) repository.…”
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Untargeted Metabolomics Reveals the Metabolic Characteristics and Biomarkers of Antioxidant Properties of Gardeniae Fructus from Different Geographical Origins in China by Wu Jiang, Lingling Jiang, Xiaoli Yin, Shuhui Zhang, Xiaojing Duan, Jiadong Chen, Yingying Liu, Hong Zheng, Zhengming Tao

“…In addition, adouetine Y, coagulin R 3-glucoside and epicatechin 3-glucoside were identified as potential biomarkers for the antioxidant activity of GF. …”
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Impact of COBIT5 Framework Application in the Efficiency and Effectiveness of Information Technology. “An Applied Analytical study of a sample of Iraqi Private Shareholding Banks”... by Abdul Ridha S. AL-Basri, Adnan Mohammmed

“…Checklist was used to collect research data and to perform statistical analysis, SPSS-19 was used to calculate (arithmetic mean, standard deviation, coefficient of difference, relative importance, T test, F test, R2 determination factor), The results confirmed the existence of a statistically significant correlation and impact of the framework (COBIT5) as an internal control tool in the Iraqi private shareholding banks, in addition to the application of the framework (COBIT5) as an internal control tool helped in the governance and management of banks as well as maximize the value and benefit through the use of technology Information. …”
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Wound repair in rabbits using autologous biomaterials combined with rosuvastatin by Yuri Ferreira Vicentini, Gisele Alborghetti Nai, Rosa Maria Barilli Nogueira, Cecília Laposy Santarém

“…A significant inverse correlation was observed between wound area and epithelial thickness with the use of aPRF (r = -0.5500). No significant difference was found in epithelial thickness between treatment groups (p > 0.05). …”
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Changes in Metabolic Regulation and the Microbiota Composition after Supplementation with Different Fatty Acids in db/db Mice by Beatriz Elina Martínez-Carrillo, Talia Mondragón-Velásquez, Ninfa Ramírez-Durán, José Félix Aguirre-Garrido, Roxana Valdés-Ramos, Ana Laura Guadarrama-López, Arturo Castillo-Cardiel

“…The lipid, hormonal profiles, and composition of the culture-dependent microbiota and the phylogenetic analysis based on the 16S rRNA gene sequencing were determined for identification of the intestinal microbiota. …”
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The genomic copy number determination of improved Cre in transgenic mice using standards derived from megaprimer PCR constructed tandem repeats by Ge Diao, Min Tian, Runbo Li, Jie Huang, Jian Han, Jianxin Guo

“…After the fragments of IL-2 (reference gene) were ligated into the same vectors, standards with copy number ratios (CNR) of 0.5, 1, 2, 4, 8, and 16 between iCre and IL-2 were completed. The R2 values of the standard curves exceeded 0.99. …”
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