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3201
Ticam2 ablation facilitates monocyte exhaustion recovery after sepsis
Published 2025-01-01“…Bearing human translational relevance, a case study of time course blood samples collected from a sepsis patient presenting with SIRS and a positive qSOFA revealed a similar effect in human monocytes, which steadily transition into an exhausted memory characterized by a CD38high; CX3CR1low; HLA-DRlow state within four days of hospital admittance. …”
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3202
Influence of fused deposition modelling printing parameters on tablet disintegration times: a design of experiments study
Published 2023-09-01“…A statistical model with accurate fit (R2 = 0.928) and predictability (Q2 = 0.847) was created. In addition, only the infill pattern and layer height influenced both the uniformity of mass and uniformity of the disintegration time, which demonstrates the robustness of the printing process.…”
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3203
A Predictive Model of Mining Collapse Extent and Its Application
Published 2019-01-01“…The slipping line angle increases along with uniform force Q and is inversely proportional to the bending stiffness. …”
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3204
Increased miRNA-375 causes oxidative damage but promotes apoptosis resistance and cell migration in the clam Ruditapes philippinarum
Published 2025-02-01“…Then, a combined approach of qRT-PCR, enzyme assay, and ultrastructure observation was applied to investigate its regulatory effects on the related genes, cellular parameters, and histological structures, respectively. …”
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3205
Health literacy levels and self-rated health in the state of Delaware: a cross-sectional study
Published 2025-01-01“…In total, 1095 participants responded to a survey questionnaire which included a validated short version of the European Health Literacy Questionnaire (HLS-EU-Q16). The data was analyzed using descriptive statistics, reliability techniques, chi-square test of independence, and ordinal logistic regression. …”
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3206
Strong reciprocal dependencies as exceptions when correlations are weak
Published 2024-06-01“…Thomas’s methodology (SV = 0.78 and SV’ = 0.72 at r = 0.15); “16PF-Q3: Low self-control – High self-control” and “16PF-L: Trusting – Suspicious” of R.B. …”
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3207
Oxytocin attenuates demand for cocaine in female rats
Published 2025-06-01“…Using a within-session threshold behavioral economics (BE) procedure, we quantified demand elasticity (a, inverse motivation) and free consumption (Q0) in male and female rats to investigate the effect of OXT on cocaine demand. …”
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3208
High-Throughput Sequencing Reveals Diverse Sets of Conserved, Nonconserved, and Species-Specific miRNAs in Jute
Published 2015-01-01“…The presence of microRNAs identified in jute was validated by stem-loop RT-PCR followed by end point PCR and qPCR for randomly selected 20 known and novel microRNAs. …”
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3209
La Norma ISO 14.063 de comunicación ambiental en la gestión de crisis organizacional
Published 2024-12-01“…Para ello se utilizó el método descriptivo, analizando las fuentes primarias (entrevistas) y secundarias (bibliografía) de información, a través del método descriptivo y la “Metodología Q” en la selección e interpretación de datos. Como resultado de la investigación se observó que en la mayoría de los casos la comunicación ambiental es poco utilizada en la planificación como medida proactiva. …”
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3210
The genomic copy number determination of improved Cre in transgenic mice using standards derived from megaprimer PCR constructed tandem repeats
Published 2024-12-01“…We demonstrate a real-time quantitative polymerase chain reaction (RT-qPCR) based method for genomic copy number determination of improved Cre (iCre), which was tested in a transgenic mouse model of CYP19A1-iCre. …”
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3211
Elevated levels of neutrophils with a pro-inflammatory profile in Turner syndrome across karyotypes
Published 2025-02-01“…All TS individuals lacked the X chromosome p-arm, and XIST expression from the q-arm did not affect the autosomal transcriptome or methylome, highlighting the critical role of the missing p-arm with its pseudoautosomal region 1. …”
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3212
Finite element-based nonlinear dynamic optimization of nanomechanical resonators
Published 2025-01-01“…The resulting methodology is used to optimize the support design of high-stress nanomechanical Si3N4 string resonators, in the presence of conflicting objectives such as simultaneous enhancement of Q-factor and nonlinear Duffing constant. To that end, we generate Pareto frontiers that highlight the trade-offs between optimization objectives and validate the results both numerically and experimentally. …”
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3213
Photochemical oxidation of short-chain polychlorinated n-alkane mixtures using H2O2/UV and the photo-Fenton reaction
Published 2004-01-01“…The photochemical oxidation of a series of short-chain polychlorinated n-alkane (PCA) mixtures was investigated using H2O2/UV and modified photo-Fenton conditions (Fe3+/H2O2/UV) in both Milli-Q and lake water. All PCA mixtures, including chlorinated (Cl5 to Cl8) decanes, undecanes, dodecanes and tridecanes degraded in 0.02 M H2O2/UV at pH 2.8 in pure water, with 80±4% disappearance after 3 h of irradiation using a 300 nm light source. …”
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3214
Syringaldehyde Alleviates Cardiac Hypertrophy Induced by Hyperglycemia in H9c2 Cells Through GLP-1 Receptor Signals
Published 2025-01-01“…Cells were treated with varying SA concentrations, and hypertrophic biomarkers were analyzed using ELISA, qPCR, and Western blot. <b>Results:</b> SA reduced cell size and hypertrophic biomarkers in a dose-dependent manner while increasing GLP-1 receptor expression and cAMP levels. …”
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3215
Glycogen Storage Disease Type IX due to a Novel Mutation in PHKA2 Gene
Published 2020-01-01“…The chromosomal microarray revealed the patient to have 1q21 duplication syndrome and 16p11.2 deletion syndrome. …”
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3216
Berberine decorated zinc oxide loaded chitosan nanoparticles a potent anti cancer agent against breast cancer
Published 2025-01-01“…Furthermore, the mRNA levels of Bax and Bcl-2 genes were quantified using qPCR. Additionally, cell migration was evaluated using a scratch assay. …”
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3217
Unveiling the Mechanisms for Decreased Glutathione in Individuals with HIV Infection
Published 2012-01-01“…We observed decreased expression of the genes coding for enzymes responsible for de novo synthesis of GSH in macrophages derived from HIV+ subjects using quantitative PCR (qPCR). Our results indicate that overproduction of proinflammatory cytokines in HIV+ individuals lead to increased production of free radicals. …”
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3218
LncRNA FAM225B Regulates PDIA4-Mediated Ovarian Cancer Cell Invasion and Migration via Modulating Transcription Factor DDX17
Published 2023-01-01“…This study aimed to explore the roles and mechanisms of lncRNA FAM225B and PDIA4 in ovarian cancer. Methods. RT-qPCR and Western blot assays were performed to detect the expression levels of the lncRNAs FAM225B, DDX17, and PDIA4 in the serum of patients with ovarian cancer and cell lines. …”
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3219
Etoricoxib–NLC Mitigates Radiation-Induced Ovarian Damage in Rats: Insights into Pro-Inflammatory Cytokines, Antioxidant Activity, and Hormonal Responses
Published 2024-12-01“…Serum levels of estrogen, FSH, and LH were measured, and gene expression analysis for <i>TGF-β</i> and <i>Nrf2</i> was performed using qRT-PCR. The findings indicate that ETO-NLC has the potential to ameliorate the harmful effects of ovarian damage induced by γ-radiation. …”
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3220
End of the world brane dynamics in holographic 4d N $$ \mathcal{N} $$ = 4 SU(N) with 3d N $$ \mathcal{N} $$ = 2 boundary conditions
Published 2025-01-01“…The 5-brane configurations turn into non-trivial (p, q) webs and lead to non-trivial brane and gauge theory phenomena, including a 5d Z 2 global gauge anomaly cancelled by a novel 6d global anomaly inflow, and the appearance of localized 3d N $$ \mathcal{N} $$ = 2 Chern-Simons couplings and the 3d parity anomaly at the boundary of the 4d theory. …”
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