Study insights in the role of PGC-1α in neurological diseases: mechanisms and therapeutic potential by Mi-bo Tang, Yi-xuan Liu, Zheng-wei Hu, Hai-yang Luo, Shuo Zhang, Chang-he Shi, Yu-ming Xu, Yu-ming Xu, Yu-ming Xu

“…Furthermore, we present the role of PGC-1α in the pathogenesis of various neurological diseases, such as intracerebral hemorrhage, ischemic stroke, Alzheimer’s disease, Parkinson’s disease, Amyotrophic lateral sclerosis, Huntington’s disease, and other PolyQ diseases. Importantly, we discuss some compounds or drug-targeting strategies that have been studied to ameliorate the pathology of these neurological diseases and introduce the possible mechanistic pathways. …”
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Localization of rust resistance genes in old local Russian flaxes by methods of classical genetics by S. N. Kutuzova, E. A. Porokhovinova, N. B. Brutch, A. V. Pavlov

“…Nine monogenic lines with the original R genes  were crossed to tester  varieties for six loci: K, L, M, N, P, and Q. F2 hybrids in the phase  of cotyledon leaves were inoculated with monopustule clones  of the  fungus,  not  virulent  to any of evaluated genes.  …”
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Genome-wide identification and expression analysis of ZF-HD family in sunflower (Helianthus annuus L.) under drought and salt stresses by Kangping Zhang, Ruqian Yan, Xiaoqing Feng, Jingjing Zhang, Yuanyuan Jiang, Lin Li, Jianzhong Guo, Xianping Zhang

“…Additionally, RNA-seq and RT-qPCR analysis revealed HaZF3 responded positively in the initial stage of drought stress, whereas a prompt and significant decrease of relative expression value in response to salt stress was showed in HaZF6 and HaZF9. …”
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Determine the Inflow Performance Relationship of Water Producing Gas Well Using Multiobjective Optimization Method by Xiao-Hua Tan, Jian-Yi Liu, Jia-Hui Zhao, Xiao-Ping Li, Guang-Dong Zhang, Chuan Tang, Li Li

“…In addition, the influence of different production gas water ratios (GWR) and gas-soluble water coefficients on absolute open flow rate (qAOF) is discussed. This method remedied the limitation of well testing on site and was considered to be a new way to analyze the production behaviors in water producing gas well.…”
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Polymorphism of the LCT gene regulatory region in Turkicspeaking populations of the Altay-Sayan region (southern Siberia) by I. V. Pilipenko, M. S. Pristyazhnyuk, V. F. Kobzev, M. I. Voevoda, A. S. Pilipenko

“…At a molecular-genetic level, lactase persistence is determined by the presence of specific alleles of polymorphic sites in cis-regulatory elements of the LCT gene located on chromosome 2q21. Ascertainment of the molecular-genetic causes of lactase persistence has made this trait one of the most convenient for studying mechanisms of human population adaptation to environmental conditions. …”
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Bibliometric and Altmetric Analysis of the 100 Most Cited Articles on Piriformis Syndrome by Burak Tayyip Dede, Muhammed Oguz, Fatih Bagcier, Ebru Aytekin

“…In the bibliometric analysis, the title, number of authors, author names (first authors and corresponding authors), year and country of publication, number of citations, citation index, genre, subject, Q classification, h-index, impact factor, and publication area were recorded. …”
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Influence of Mesalazine on Ferroptosis-Related Gene Expression in In Vitro Colorectal Cancer Culture by Joanna Słoka, Barbara Strzałka-Mrozik, Sebastian Kubica, Ilona Nowak, Celina Kruszniewska-Rajs

“…Cytotoxicity was assessed using the MTT assay, while ferroptosis-related gene expression analysis was performed using oligonucleotide microarrays, with RT-qPCR used for validation. <b>Results:</b> MES effectively reduces the viability of DLD-1 cells while minimally affecting normal intestinal cells. …”
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High Doses of Halotolerant Gut-Indigenous Lactobacillus plantarum Reduce Cultivable Lactobacilli in Newborn Calves without Increasing Its Species Abundance by Alexander Rodriguez-Palacios, Henry R. Staempfli, J. Scott Weese

“…In a double-blind placebo-randomized trial twelve colostrum-fed calves, consecutively born at a farm, were fed L. plantarum within 12 hours from birth at low (107-8 CFU/day) or high concentrations (1010-11) or placebo (q24 h, 5 d; 10 d follow-up). We developed a 2.5% NaCl-selective culture strategy to facilitate the enumeration of L. plantarum-strain-B80, and tested 384 samples (>1,152 cultures). …”
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Causal association among smoking, bitter beverage consumption, and risk of osteoporosis: a two-sample mendelian randomization-based study by Yanqian Wu, Jianqian Chao, Min Bao, Na Zhang, Leixia Wang

“…The stability and reliability of the results were verified by the Cochran’s Q test, the Egger-intercept test, and the leave-one-out analysis. …”
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Cell-Specific Regulation of Inflammatory Cytokines and Acute-Phase Proteins by the Glucocorticoid Receptor by Rebecca Winkler, Hong Lu

“…Primary human hepatocytes (PHH) were treated with combinations of tumor necrosis factor alpha (TNFα), lipopolysaccharide (LPS), and dexamethasone (DEX) for 24 h, following which chemokine mRNA and protein expression were analyzed using qPCR and enzyme-linked immunosorbent assay assays. …”
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Novel PITX2 Mutations including a Mutation Causing an Unusual Ophthalmic Phenotype of Axenfeld-Rieger Syndrome by Liqin Huang, Yong Meng, Xiangming Guo

“…Sequence analysis of the PITX2 gene revealed four mutations, including c.475_476delCT (P.L159VfsX39), c.64C > T (P.Q22X), c.296delG (P.R99PfsX56), and c.206G > A (P.R69H). …”
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circHUWE1 Exerts an Oncogenic Role in Inducing DDP-Resistant NSCLC Progression Depending on the Regulation of miR-34a-5p/TNFAIP8 by Xueliang Yang, Quan Sun, Yongming Song, Wenli Li

“…The quantitative real-time polymerase chain reaction (RT-qPCR) and western blot analyses were used for examining circHUWE1, microRNA-34a-5p (miR-34a-5p), and tumor necrosis factor alpha-induced protein 8 (TNFAIP8). …”
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A meta-analysis and systematic review of the clinical efficacy and safety of platelet-rich plasma combined with hyaluronic acid (PRP + HA) versus PRP monotherapy for knee osteoarth... by Dan Du, Yuan Liang

“…We assessed heterogeneity using Cochrane Q and I2statistics and the appropriate p-value. …”
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Jiaweishaoyao Decoction Alleviates DSS-Induced Ulcerative Colitis via Inhibiting Inflammation by Huixia Qiao, Yahui Huang, Xiaoyan Chen, Long Yang, Yue Wang, Rongrong Xu

“…The levels of TNF-α, IL-1β, and IL-6 were analyzed by ELISA and qRT-PCR. The levels of NLRP3 inflammasome- and NF-κB pathway-associated proteins were measured by western blot. …”
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منهجية الرسول صلى الله عليه وسلم في توظيف الطاقات by محمد سرحان علي قاسم

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Arabidopsis Calcium Dependent Protein Kinase 3, and Its Orthologues OsCPK1, OsCPK15, and AcCPK16, Are Involved in Biotic and Abiotic Stresses by Gardette R. Valmonte-Cortes, Colleen M. Higgins, Robin M. MacDiarmid

“…Reverse-transcriptase quantitative PCR (RT-qPCR) analysis revealed that <i>OsCPK1</i> and <i>AcCPK16</i> exhibit similar responses to stressors to <i>AtCPK3</i>. …”
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A Cocktail Method for Promoting Cardiomyocyte Differentiation from Bone Marrow-Derived Mesenchymal Stem Cells by Qing Gao, Maojuan Guo, Xijuan Jiang, Xiantong Hu, Yijing Wang, Yingchang Fan

“…Immunofluorescence results showed that cTnT expression in the 5-aza+salB+CLM group was stronger than other groups. Real-time qPCR and Western blotting analyses showed that cTnT, alpha-cardiac actin, mef-2c, Cx43, and GSK-3beta expression increased while beta-catenin expression decreased. …”
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Ensemble machine learning models for lung cancer incidence risk prediction in the elderly: a retrospective longitudinal study by Songjing Chen, Sizhu Wu

“…For each subgroup, random forest, extreme gradient boosting, deep neural networks, support vector machine, multiple logistic regression and deep Q network (DQN) models were developed and validated. …”
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Non-invasive electroencephalogram-based anesthesiological monitoring in geriatric patients in the ent-surgery by Medhat H. Altoufaili, Tatiana V. Klypa, Irina A. Mandel, Maria S. Orekhova

“…The optimization of the dosage of opioids with controlling the anesthesia depth index (the Nociception Index, qNOX) positively affects the postoperative cognitive status of the patients.…”
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Environmental DNA and Hydroacoustic Surveys for Monitoring the Spread of the Invasive European Catfish (<i>Silurus glanis</i> Linnaeus, 1758) in the Guadalquivir River Basin, Spain by Ruth Coya, Amadora Rodríguez-Ruiz, Álvaro Fueyo, Carlos Orduna, Laura Miralles, Ilaria de Meo, Trinidad Pérez, Juan Ramón Cid, Carlos Fernández-Delgado, Lourdes Encina, Yaisel J. Borrell, Carlos Granado-Lorencio

“…The hydroacoustic profiles and the species-specific detections by real-time PCR (qPCR) and droplet digital PCR (ddPCR) showed that these non-invasive methods allow the detection and quantification of catfish and provide valuable information on the species’ presence. …”
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