DICER1: The Argonaute Endonuclease Family Member and Its Role in Pediatric and Youth Pathology by Consolato M. Sergi, Fabrizio Minervini

“…It is a gene, which has been positioned on chromosome 14q32.13. It contains 27 exons, which are linking the two enzyme domains. …”
Get full text

Circulating CTRP1 Levels Are Increased and Associated with the STOD in Essential Hypertension in Chinese Patients by Zhengjia Su, Shuya Tian, Wei Liang

“…This study aimed to investigate the correlation between complement C1q tumor necrosis factor-related protein 1 (CTRP1) and subclinical target organ damage (STOD) in essential hypertension (EH). 720 patients were enrolled in this study, including 360 healthy subjects and 360 patients with EH. …”
Get full text

The Relationship between Statin and Risk of Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis by Ezatollah Memarzadeh, Saeid Heidari-Soureshjani

“…Subgroup analyses and sensitivity analyses were also conducted. Cochran’s Q test and the I2 statistic were used to evaluate the heterogeneity. …”
Get full text

Time Domain Equalization and Digital Back-Propagation Method-Based Receiver for Fiber Optic Communication Systems by Fazal Muhammad, Farman Ali, Usman Habib, Muhammad Usman, Imran Khan, Sunghwan Kim

“…The simulations are performed considering Dual Polarization- (DP-) QPSK modulation format to achieve two-fold data rate to achieve spectral efficiency of 3.28 bits/s/Hz by making use of the polarization diversity and system performance is investigated in terms of bit error rate (BER), constellation diagrams, and quality factor (Q-factor) for different values of optical signal-to-noise ratio (OSNR), launch power (PL), and fiber length.…”
Get full text

lncRNA RUNDC3A-AS1 Regulates Proliferation and Apoptosis of Thyroid Cancer Cells via the miR-151b/SNRPB Axis by Yan Deng, Jie Wu, Xin Li

“…Relative expression levels of RUNDC3A-AS1, microRNA (miR)-151b, and small nuclear ribonucleoprotein polypeptides B and B1 (SNRPB) were examined by reverse transcription quantitative polymerase chain reaction (RT-qPCR) in THCA cells. The localization of RUNDC3A-AS1 in THCA cells was detected by subcellular fractionation assay. …”
Get full text

Quantitative Determination of 7 Saikosaponins in Xiaochaihu Granules Using High-Performance Liquid Chromatography with Charged Aerosol Detection by Aoxue Liu, Tongtong Xu, Wenning Yang, Dandan Zhou, Yiwei Sha

“…In this manuscript, the simultaneous determination of 7 saikosaponins (saikosaponins C, I, H, A, B2, G, and B1) in XG by HPLC with charged aerosol detection (CAD) and confirmation by LC-Q-Orbitrap HRMS were described. The saikosaponins were purified on an SPE cartridge and determined on a Waters CORTECTS C18 column (4.6 mm × 150 mm, 2.7 μm) by gradient elution using 0.01% acetic acid aqueous solution and acetonitrile. …”
Get full text

Multifeature Extraction of Three-Dimensional Topography of Carbon Steel Specimen during Fatigue Process by Tao Liu, Jingxiong Wu, Jingfa Lei, Xue Wang, Bingqi Zhang, Shu Zhang

“…In order to investigate the variation of three-dimensional metal surface topography during fatigue process, a three-dimensional (3D) topography acquisition platform was built with an in situ tensile tester and a three-dimensional profilometer. Q235 steel specimens were chosen as research objects, and the three-dimensional surface topography information at various stages of fatigue damage was obtained. …”
Get full text

In Vivo Hypoglycaemic Effect and Inhibitory Mechanism of the Branch Bark Extract of the Mulberry on STZ-Induced Diabetic Mice by Hua-Yu Liu, Meng Fang, Yu-Qing Zhang

“…To understand this therapeutic effect and the regulatory mechanisms of BBE in diabetic mice, a qRT-PCR experiment was performed, indicating that the mulberry BBE can regulate the mRNA expression of glycometabolism genes in diabetic mice, including glucose-6-phosphatase (G6Pase), glucokinase (GCK), and phosphoenolpyruvate carboxykinase (PEPCK), thereby regulating sugar metabolism and reducing the blood glucose level in diabetic mice. …”
Get full text

Pax6 regulates neuronal migration and cell proliferation via interacting with Wnt3a during cortical development by Bichao Zhang, Meihua Hou, Jiayan Huang, Yunfei Liu, Ciqing Yang, Juntang Lin

“…JASPAR analysis together with the results of qPCR, Western blot, CUT&Tag, and rescue experiments revealed that Pax6 regulates neuronal migration and cell proliferation by indirectly mediating Wnt3a expression. …”
Get full text

Percepción de estudiantes a distancia sobre la influencia de las TIC en su formación académica by Ingrid del Carmen Blanco-Hernández, Dayana Carolina Arias Pertuz, Martha Lucia Franco-Fajardo, Nelsy Maria Miranda-Pájaro

“…A partir de los resultados obtenidos, se concluye que la percepción que tienen los estudiantes sobre la influencia de las TIC en su formación académica es altamente significativa, además consideran que la institución en cuestión debe mejorar su infraestructura tecnológica.CLASIFICACIÓN JEL123, O32, O33, M15, Q55, 123…”
Get full text

Prolapsus Rektum Pada Domba Dorper (Case Report: Rectal Prolapses in Dorper Sheep) by Artina Prastiwi, Dhirgo Adji, Rr. Devita Anggraeni, Agus Purnomo, Mungky Emma Ramadhani

“…Terapi post operatif diberikan injeksi antibiotik broad spectrum Amoxicillin dengan sediaan 150 mg/ml (1 ml/10kg BB) dan injeksi antiinflamasi (NSAIDs) Flunixin Meglumine 50 mg/ml (0,02-0,04 ml/kg BB; q12h). Domba Dorper jantan dipotong karena mengalami prolaps rektum berulang dan lemah.…”
Get full text

Gut microbiota in patients with sarcopenia: a systematic review and meta-analysis by Guangning Wang, Yujie Li, Huisong Liu, Xinjuan Yu

“…Overall effect was measured using Hedges’s g and determined using Z-statistics. Cochran’s Q test and I2 were used to investigate heterogeneity. …”
Get full text

Altered Expressions of miR-1238-3p, miR-494, miR-6069, and miR-139-3p in the Formation of Chronic Brucellosis by Ferah Budak, Salih Haldun Bal, Gulcin Tezcan, Halis Akalın, Guher Goral, Haluk Barbaros Oral

“…Here, more than 2000 miRNAs were screened in peripheral blood mononuclear cells (PBMCs) of patients with acute or chronic brucellosis and healthy controls by using miRNA array, and the results of the miRNA array were validated through qRT-PCR. Findings were evaluated using GeneSpring GX (Agilent) 13.0 software and KEGG pathway analysis. …”
Get full text

GABA promotes peroxisome proliferation in Triticum monococcum leaves by Yunus Şahin, Taras Nazarov, Ercan Selçuk Ünlü, Andrei Smertenko, Nusret Zencrici

“…We tested the outcome of RNA‐seq analysis by qRT‐PCR in developing Triticum monococcum ssp. monococcum (Einkorn) seedlings. …”
Get full text

CRIP1 inhibits cutaneous melanoma progression through TFAM-mediated mitochondrial biogenesis by Jianqiang Wu, Lixia Chen, Peijun Wen

“…Real-time quantitative polymerase chain reaction (RT-qPCR) and Western blots (WB) were used to detect stable overexpression and knockdown of CRIP1 in melanoma cells. …”
Get full text

YgaE Regulates Out Membrane Proteins in Salmonella enterica Serovar Typhi under Hyperosmotic Stress by Min Wang, Ping Feng, Xun Chen, Haifang Zhang, Bin Ni, Xiaofang Xie, Hong Du

“…In this study, we constructed ΔygaE mutant and a microarray was performed to investigate the role of ygaE in regulation of gene expression changes in response to hyperosmotic stress in S. Typhi. qRT-PCR was performed to validate the microarray results. …”
Get full text

Identification of Suitable Natural Inhibitor against Influenza A (H1N1) Neuraminidase Protein by Molecular Docking by Maheswata Sahoo, Lingaraja Jena, Surya Narayan Rath, Satish Kumar

“…We employed amino acid sequence of H1N1 NA to predict the tertiary structure using Phyre2 server and validated using ProCheck, ProSA, ProQ, and ERRAT server. Further, the modelled structure was docked with thirteen natural compounds of plant origin using AutoDock4.2. …”
Get full text

Cuproptosis-related lncRNAs and genes: Potential markers for glioblastoma prognosis and treatment. by Yajia Chen, Jingxian Zhang, Weiqian Zheng, Hongwu Xu

“…Two high-risk CRLs (AC091182.2, AC005229.4) and their co-expression CRGs (LIPT2, GLS) were identified and verified to constitute an independent prognostic indicator of GBM. RT-qPCR analysis confirmed that the high-risk CRLs and CRGs were highly expressed in GBM cells compared to normal astrocytes. …”
Get full text

METAPHORICAL TERMINOLOGY IN ANCIENT TEXTS OF TRADITIONAL CHINESE MEDICINE: PROBLEMS OF UNDERSTANDING AND TRANSLATION by Qiuhua Sun, Irina S. Karabulatova, Jinna Zou, Chen Kuo

Get full text

Development and Validation of a Stability-Indicating HPLC Method for the Simultaneous Determination of trans-Resveratrol and cis-Resveratrol in an Injectable Solution by Esmeralda Mota-Lugo, Mariana Dolores-Hernández, Elvia A. Morales-Hipólito, Iris A. Blanco-Alcántara, Hugo Cuatecontzi-Flores, Raquel López-Arellano

“…The validation met the ICH Q2 criteria of specificity, method linearity (2.8–4.2 μg/ml), precision and accuracy, robustness, quantification limit (0.176 μg/ml), and detection (0.058 μg/ml). …”
Get full text