Novel digital droplet inverse PCR assay shows that natural clearance of hepatitis B infection is associated with fewer viral integrations by Dong Li, Vikki Ho, Chiao-Fang Teng, Hung-Wen Tsai, Yuanyuan Liu, Sarah Bae, Harout Ajoyan, Jochen M. Wettengel, Ulrike Protzer, Brian S. Gloss, Rebecca J. Rockett, Rafid Al Asady, Jane Li, Simon So, Jacob George, Mark W. Douglas, Thomas Tu

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Hyperglycemia and Correlated High Levels of Inflammation Have a Positive Relationship with the Severity of Coronavirus Disease 2019 by Wen Zhang, Chuanwei Li, Yu Xu, Binfeng He, Mingdong Hu, Guoqiang Cao, Li Li, Shuang Wu, Xia Wang, Chun Zhang, Jianping Zhao, Jungang Xie, Zihui Xu, Qi Li, Guansong Wang

“…Coronavirus disease 2019 (COVID-19) is a considerable global public health threat. This study sought to investigate whether blood glucose (BG) levels or comorbid diabetes are associated with inflammatory status and disease severity in patients with COVID-19. …”
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Impact of infection in patients with non-ST elevation acute coronary syndrome undergoing percutaneous coronary intervention: insight from a multicentre observational cohort from Ch... by Jun Li, Lei Jiang, Wei Chen, Ning Tan, Wei Guo, Ji-yan Chen, Yuan-hui Liu, Peng-cheng He, Peng-Yuan Chen, Chong-Yang Duan, Xue-Biao Wei, Yin-Lin Zhou, Zhu-Jun Chen, Jian-Fang Luo, Dan-Qing Yu, Qing-Shan Geng, Chun-Ying Lin, Zhi-Qiang Guo, Yan-Song Guo, Yi-Yue Chen, Wen-Sheng Li

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Assessing Mental Illness Referral Request Acceptance: A Nationwide E-Referral Data From Saudi Arabia by Alharbi AA, Aljerian NA, Alghamdi HA, Binhotan MS, Alsultan AK, Arafat MS, Aldhabib A, Aloqayli AI, Alwahbi EB, Horner RD

“…Abdullah A Alharbi,1 Nawfal A Aljerian,2– 4 Hani A Alghamdi,5 Meshary S Binhotan,4,6 Ali K Alsultan,2 Mohammed S Arafat,2 Abdulrahman Aldhabib,2 Ahmed I Aloqayli,2 Eid B Alwahbi,2 Ronnie D Horner7 1Family and Community Medicine Department, Faculty of Medicine, Jazan University, Jazan City, Kingdom of Saudi Arabia; 2Medical Referrals Centre, Ministry of Health, Riyadh, Kingdom of Saudi Arabia; 3Emergency Medical Services Department, College of Applied Medical Sciences, King Saud Bin Abdulaziz University for Health Science, Riyadh, Kingdom of Saudi Arabia; 4King Abdullah International Medical Research Centre, Riyadh, Kingdom of Saudi Arabia; 5Department of Family and Community Medicine, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia; 6Emergency Medical Services Department, College of Applied Medical Sciences, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Kingdom of Saudi Arabia; 7Health Services Research and Administration Department, College of Public Health, University of Nebraska Medical Center, Omaha, NE, USACorrespondence: Meshary S Binhotan, Emergency Medical Services Department, College of Applied Medical Sciences, King Saud bin Abdulaziz University for Health Sciences, Riyadh, 22490, Kingdom of Saudi Arabia, Email hotanm@ksau-hs.edu.saBackground and Objective: Mental disorders significantly impact quality of life and life expectancy, representing a leading cause of global disease burden. …”
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Association between alkali and alkaline earth elements in chorionic villus and risk for spontaneous abortion by Meng Lin, Yutong Wang, Xiaoye Wang, Lailai Yan, Linlin Wang, Chan Tian

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Review and Prospect of Research on Urban Walking Safety and Environmental Influencing Factors Thereof by Lin LI, Yu YE, Yong CHEN

“…ObjectiveWalking space is an important part of urban public space, and its spatial quality is a basis for the construction of walkable cities, which directly affects residents’ travel willingness and walking experience.MethodsThis research takes relevant literature on walking safety screened from Web of Science and CNKI databases spanning the period from 1975 to 2022 as research object, and analyzes the distribution characteristics of literature related to the current research on walking safety and environmental influencing factors thereof, as well as such contents as research context and research hotspots.ResultsFirstly, from the perspective of literature distribution, a large number of works of scholars in such fields as traffic engineering, public health and sociology have been cited in literature on walking safety, reflecting that pedestrians’ activity safety, traffic safety and security needs are important directions to promote the research on walking safety. …”
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On the issue of creating an algorithm for assessing safety culture in modern healthcare institutions by O.P. Yavorovsky, I.V. Serheta, R.P. Brukhno, Yu.M. Skaletskyi, V.D. Chopchyk, D.V. Varyvonchyk, V.I. Zenkina

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Exploring the role of district clinical specialist teams in maternal health outcomes in a South African district: A mixed method study from 2012 to 2020 by J Basu, A Stewart, D Basu, J Wing, U Feucht

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Exploring the Relationship Between Sleep Apnea, Myocardial Infarct Size, and Coronary Collaterals in Acute Myocardial Infarction: A Multidisciplinary Study by Kundel V, Devarakonda K, Khan S, Suarez-Farinas M, Cohen O, Santos-Gallego C, Menegus MA, Kini A, Vengrenyuk Y, Okamoto N, Ueda H, Gidwani U, Kizer JR, Redline S, Kaplan R, Shah N

“…Vaishnavi Kundel,1 Kavya Devarakonda,1 Samira Khan,1 Mayte Suarez-Farinas,1 Oren Cohen,1 Carlos Santos-Gallego,1 Mark A Menegus,2 Annapoorna Kini,1 Yuliya Vengrenyuk,1 Naotaka Okamoto,1 Hiroshi Ueda,1 Umesh Gidwani,1 Jorge R Kizer,3 Susan Redline,4 Robert Kaplan,2,5 Neomi Shah1 1Icahn School of Medicine at Mount Sinai, New York, NY, USA; 2Albert Einstein College of Medicine, Bronx, NY, USA; 3Cardiology Section, San Francisco Veterans Affairs Health Care System and Departments of Medicine, Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, USA; 4Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA; 5Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USACorrespondence: Vaishnavi Kundel, Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, Icahn School of Medicine at Mount Sinai, One Gustave L Levy Place, Box 1232, New York, NY, 10029, USA, Tel +1-212-241-1967, Email Vaishnavi.kundel@mssm.eduPurpose: We designed a study investigating the cardioprotective role of sleep apnea (SA) in patients with acute myocardial infarction (AMI), focusing on its association with infarct size and coronary collateral circulation.Methods: We recruited adults with AMI, who underwent Level-III SA testing during hospitalization. …”
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Successful Management of Peri-Implantitis around Short and Ultrashort Single-Crown Implants: A Case Series with a 3-Year Follow-Up by Giorgio Lombardo, Mauro Marincola, Andrea Cicconetti, Miguel Angel Simancas-Pallares, Jacopo Pighi, Jeffrey Lehrberg, Annarita Signoriello, Giovanni Corrocher, Xiomara Serpa-Romero, Luis Armando Vila Sierra, Luisa Arevalo-Tovar, Pier Francesco Nocini

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Relationship between internet gaming disorder, interpersonal needs, loneliness, and depression among adolescents using a chain mediation model by GAO-QU Yige, MUZAI Baier, DONG Jingwen, ZHAO Yuxi, ZHU Pengyu, GU Xicheng, LIU Shangbin, CAI Yong, YUAN Dong, WANG Ying

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Association Between SHBG Levels and Hypertensive Disorders of Pregnancy: A Systematic Review and Meta‐Analysis by Ajay Malvi, Muhammed Shabil, Mahalaqua Nazli Khatib, Roopashree R, Mandeep Kaur, Manish Srivastava, Amit Barwal, G. V. Siva Prasad, Pranchal Rajput, Rukshar Syed, Kamal Kundra, Vinamra Mittal, Amit Kumar, Pancham Cajla, Ganesh Bushi, Rachana Mehta, Zaid Khan, Prakasini Satapathy, Shilpa Gaidhane, Renu Sah

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Trial protocol of an open-label pilot study of oral naltrexone–bupropion combination pharmacotherapy for the treatment of methamphetamine use disorder (the NABU trial) by Jonathan Brett, Paul S Haber, Nicholas Lintzeris, Didier Jutras-Aswad, Nadine Ezard, Brendan Clifford, Krista J Siefried, Adrian John Dunlop, Liam Acheson, Carl Moller, Michael Christmass, Kirsten Morley, Steven Shoptaw, Madhukar H Trivedi

“…Introduction Methamphetamine use disorder is a global public health concern with no approved pharmacotherapies for its treatment. …”
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Therapeutic potential of the neutralizing monoclonal antibody 45G3 against encephalomyocarditis virus by Yanfang Zhang, Zhiying Wang, Yaohui Fang, Qiong Zhu, Jie Fu, Sijing Hu, Jiayin Jin, Min Zhou, Xijia Liu, Danna Zhang, Shouwei Huang, Yali Deng, Lingling Xie, Shu Shen, Jing Ye, Fei Deng, Shengbo Cao

“…Abstract Encephalomyocarditis virus (EMCV), a potential zoonotic pathogen, poses significant socioeconomic and public health challenges across various host species. …”
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DepRescribing inapprOpriate Proton Pump InhibiTors (DROPIT): study protocol of a cluster-randomised controlled trial in Swiss primary care by Stefan Neuner-Jehle, Katharina Tabea Jungo, Sven Streit, Sven Trelle, Nicolas Rodondi, Carole Elodie Aubert, Kristie Rebecca Weir, Enriqueta Vallejo-Yagüe, Samantha Chan, Marie Roumet, Pascal Juillerat, Sofia Carolina Zambrano Ramos, Jennifer Inauen, Angela Edith Schulthess-Lisibach, Renata Vidonscky Lüthold, Clémentine Tombez, Martina Zangger, Flurina Jenal, Yvonne Mattmann, Christof Bieri, Michaela Barbier

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Clinical integration of germline findings from a tumor testing precision medicine program by Maria Carolina Sanabria-Salas, Nina C. Anggala, Brittany Gillies, Kirsten M. Farncombe, Renee Hofstedter, Larissa Peck, Helia Purnaghshband, Laura Redondo, Emily Thain, Wei Xu, Peter Sabatini, Philippe L. Bedard, Raymond H. Kim

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CD94-driven in vitro expansion of highly functional adaptive NKG2C+ NKG2A- CD57+ NK cells from CMV+ healthy donors by Chiara Giordano, Simona Carlomagno, Simona Carlomagno, Michela Falco, Claudia Cantoni, Claudia Cantoni, Massimo Vitale, Ignazio Caruana, Johannes Dirks, Alberto Serio, Letizia Muccio, Giulia Bartalucci, Alessandra Bo, Franco Locatelli, Franco Locatelli, Cristina Bottino, Cristina Bottino, Simona Sivori, Simona Sivori, Mariella Della Chiesa, Mariella Della Chiesa

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Neutrophil elastase inhibitor (Sivelestat) in the treatment of acute respiratory distress syndrome induced by COVID-19: a multicenter retrospective cohort study by Yuting Li, Jianjun Zhao, Jiahui Wei, Yanhong Zhang, Haitao Zhang, Ying Li, Ting Liao, Yang Hu, Bo Yuan, Xinmei Zhang, Wanyan Liu, Changgang Liu, Qingsong Cui, Shunzi Wu, Hongmei Jiang, Wenge Liu, Weiheng Liu, Hongguang Xu, Gang Li, Yuyan Cai, Liting Chen, Bingwei Chen, Dong Zhang

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PET/CT-derived coronary calcium score may predict cardiac complications in anthracycline-treated patients with lymphoma by Genevieve Douglas, Zoe Loh, Evonne S.Y. Shum, Sze-Ting Lee, Niamh Waters, Garry Hamilton, Geoffrey Chong, Alexandra C. Murphy, Eliza A. Hawkes

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Key prognostic risk factors linked to poor functional outcomes in cerebral venous sinus thrombosis: a systematic review and meta-analysis by Lili Lin, Senfeng Liu, Wei Wang, Xiao-kuo He, Muhammad Hibatullah Romli, Ruthpackiavathy Rajen Durai

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