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Identification of therapeutic target genes for age-related hearing loss through systematic genome-wide mendelian randomization of druggable genes
Published 2025-02-01“…Background: Age-related hearing loss (ARHL) is a common sensory disorder with significant public health implications. However, few effective treatment options are available. …”
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11563
Detections of antimicrobial resistance phenotypes and extended-spectrum beta-lactamase (ESBL)- producing Salmonella spps and Escherichia coli O157:H7 in raw vegetables and fruits f...
Published 2025-02-01“…In addition, this study provided data on the hygiene and handling practices of vendors, which can help as impute to improve food safety and safeguard public health. A total of 242 salad samples were collected from three different kebeles and examined for the presence of Salmonella spp. and E. coli O157:H7 in the microbiology laboratory of Jimma University by using conventional microbiological techniques. …”
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11564
Highly Sensitive In Vivo Imaging of Bacterial Infections with a Hydrophilicity‐Switching, Self‐Immobilizing, Near‐Infrared Fluorogenic β‐Lactamase Probe Enriched within Bacteria...
Published 2025-02-01“…Abstract The emergence of antibiotic resistance, particularly bacterial resistance to β‐lactam antibiotics, the most widely prescribed therapeutic agents for infectious diseases, poses a significant threat to public health worldwide. The discovery of effective therapies against antibiotic‐resistant pathogens has become an urgent need, necessitating innovative approaches to accelerate the identification and development of novel antibacterial agents. …”
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11565
Trends and future predictions of chronic kidney disease due to diabetes mellitus type 2 attributable to dietary risks: insights based on GBD 2021 data
Published 2025-01-01“…Socio-demographic index (SDI) is negatively correlated with the CKD-T2DM burden attributable to dietary risk factors.ConclusionPublic health interventions that target dietary changes can significantly reduce the global burden of CKD-T2DM.…”
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2-Aminothiophene Derivatives—New Drug Candidates Against Leishmaniasis: Drug Design, Synthesis, Pharmacomodulation, and Antileishmanial Activity
Published 2025-01-01“…<b>Background/Objectives</b>: Leishmaniasis is one of the 20 Neglected Tropical Diseases according to the WHO, affecting approximately 12 million people in four continents, generating serious public health problems. The lack of therapeutic options, associated with toxicity and the emergence of resistance to the few available drugs, makes it urgent to develop new drug options. …”
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Determinants of Physicochemical Composition of Palm Oil Mill Effluent - Implications on Environment and Bio-digester Treatment Design
Published 2024-12-01“…From a randomly sampled small-scaled mill in each community, and for the lone medium and large-scaled mills, four homogenous samples of POME were collected from sampled small, medium and large-scaled mills for laboratory analysis of potential of hydrogen (pH), dissolved oxygen (DO), biochemical oxygen demand (BOD), chemical oxygen demand (COD), total carbon (TC), total solid (TS), total suspended solid (TSS), total organic carbon (TOC), total nitrogen (TN), total kjeldahl nitrogen (TKN), ammonia nitrogen (NH3-N), Manganese (Mn), Nickel (Ni), Iron (Fe), Copper (Cu), Chromium (Cr), Cadmium (Cd), Potassium (K), total phosphorus (TP), Calcium (Ca), and Magnesium (Mg) using standard methods for wastewater analysis as described in American Public Health Association. Data was analysed using multivariate analysis of variance, and showed that the physicochemical composition of POME was significantly different (p<0.01) across milling-scales, types of FFBs and seasons. …”
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Self-Management Strategies for Low Back Pain Among Horticulture Workers: Protocol for a Type II Hybrid Effectiveness-Implementation Study
Published 2025-01-01“…If self-management is effective, mitigating pain positively impacts quality of life, productivity, and retention, while increasing the use of nonpharmacological alternatives to opioids addresses an important public health issue. Implementation aims will help inform reasons for results, barriers and facilitators, and potential for similar interventions in these and similar industries with physically challenging outdoor work. …”
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Overexpression of multiple cytochrome P450 genes with and without knockdown resistance mutations confers high resistance to deltamethrin in Culex quinquefasciatus
Published 2025-01-01“…This study supports sustainable public health initiatives in Thailand to address the evolving challenges of insecticide resistance.…”
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Snacking Behaviour and Its Determinants among College-Going Students in Coastal South India
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Machine and deep learning algorithms for sentiment analysis during COVID-19: A vision to create fake news resistant society.
Published 2024-01-01“…The spread of fake news during the COVID-19 pandemic has created significant challenges for public health and safety because misinformation about the virus, its transmission, and treatments has led to confusion and distrust among the public. …”
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Children and providers’ perspectives on once-weekly rifapentine and isoniazid TB preventive therapy
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