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Comprehensive analysis of the succinylome in Vero cells infected with peste des petits ruminants virus Nigeria 75/1 vaccine strain
Published 2025-01-01“…Results In this study, a global profile of the succinylome in Vero cells infected with PPRV Nigeria 75/1 vaccine strain (PPRVvac) was performed by dimethylation labeling-based quantitative proteomics analysis. A total of 2633 succinylation sites derived from 823 proteins were quantified. …”
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582
Addressing genome scale design tradeoffs in Pseudomonas putida for bioconversion of an aromatic carbon source
Published 2025-01-01“…In this study glutamine is then converted to indigoidine, an alternative sustainable pigment and a model heterologous product that is commonly used to colorimetrically quantify glutamine concentration. Through proteomics, promoter-variation, and growth characterization of a fully implemented gene deletion design, we provide evidence that aromatic catabolism in the completed design is rate-limited by fumarase hydratase (FUM) enzyme activity in the citrate cycle and requires careful optimization of another fumarate hydratase protein (PP_0897) expression to achieve growth and production. …”
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583
Regulation of interferon alpha production by the MAGUK-family protein CASK under H5N1 infection
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584
Nutrigenomics: A promising frontier in chronic disease prevention
Published 2024-12-01“…These include the integration of diverse and complex datasets from various sources -such as genomics, metabolomics, and proteomics- the development of robust bioinformatics tools for data analysis and interpretation, and careful consideration of ethical implications, including privacy concerns and the potential for genetic discrimination.Moving forward, the integration of multi-omics approaches -encompassing a comprehensive analysis of an individual's genetic, epigenetic, metabolic, and proteomic profiles- will be crucial for advancing the field of nutrigenomics. …”
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585
Characterizing the Contaminant-Adhesion of a Dibenzofuran Degrader <i>Rhodococcus</i> sp.
Published 2025-01-01“…Compared with sodium acetate as a carbon source, the percentages of glucose and proteins related to electron transfer, toxin–antitoxin, and stress responses were elevated, which were analyzed by polysaccharide composition and proteomics, and the contents of extracellular polysaccharides and proteins were increased. …”
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586
Prioritization of potato genes involved in the formation of agronomically valuable traits using the SOLANUM TUBEROSUM knowledge base
Published 2019-05-01“…The development of highly efficient technologies in genomics, transcriptomics, proteomics and metabolomics, as well as new technologies in agriculture has led to an “information explosion” in plant biology and crop production, including potato production. …”
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587
Encapsulated LyeTx III Peptide: Cytotoxic Agent Isolated from <i>Lycosa erythrognatha</i> Spider Venom
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588
Seed priming and abiotic stress tolerance in carrot: Unraveling the mechanisms of improved germination.
Published 2025-01-01“…., transcriptomics, proteomics, metabolomics) will provide deeper insights into the molecular mechanisms that regulate stress tolerance, to aid in the development of more resilient carrot varieties suitable for cultivation under adverse environmental conditions.…”
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589
Broad substrate scope C-C oxidation in cyclodipeptides catalysed by a flavin-dependent filament
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590
Triple-negative breast cancer modifies the systemic immune landscape and alters neutrophil functionality
Published 2025-01-01“…Chemotherapy-naïve mTNBC patients showed increased classical monocytes and neutrophils. Transcriptional, proteomic, and functional analyses revealed that neutrophils in mTNBC exhibited enhanced migratory capacity, elevated granule proteins, and higher ROS production. …”
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591
The effect of resveratrol on the cryopreservation of Mongolian horse semen
Published 2025-01-01“…The study also employed tandem mass tag (TMT) quantitative proteomics technology to explore differential proteins and their pathways. …”
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592
Total synthesis and target identification of marine cyclopiane diterpenes
Published 2024-12-01“…Herein, we report our synthetic and chemical proteomics studies of cyclopiane diterpenes which culminate in the asymmetric total synthesis of conidiogenones C, K and 12β-hydroxy conidiogenone C, and identification of Immunity-related GTPase family M protein 1 (IRGM1) as a cellular target. …”
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593
Salivary Protein Profile and Food Intake: A Dietary Pattern Analysis
Published 2021-01-01“…Our results support the association of salivary proteomics and different dietary patterns and highlight the need of considering food consumption habits in studies using saliva, since this is a factor associated with variations in the composition of this fluid.…”
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Immediate Respiratory Warm-Up Effect on Dynamic Inspiratory Muscle Strength in Cardiac Surgery Candidates
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597
Human milk and bronchopulmonary dysplasia have a dose-dependent effect: a cohort study
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598
Is the convergence insufficiency symptom survey applicable to elderly individuals?
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599
Mesenchymal stem cell‐derived exosomes mitigate amyloid β‐induced retinal toxicity: Insights from rat model and cellular studies
Published 2025-01-01“…Fluorescent labelling demonstrated increased migration of AT‐MSC‐Exosomes towards retinal cells under conditions of amyloid‐related toxicity. Proteomic analysis indicated a decrease in the retinal levels of heat‐shock proteins activated by pathogenic Aβ fibrils following AT‐MSC‐Exosome treatment. …”
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600
Spatial transcriptomic analysis drives PET imaging of tight junction protein expression in pancreatic cancer theranostics
Published 2024-12-01“…While cancer-associated fibroblasts and integrins have been proposed as targets for imaging of pancreatic ductal adenocarcinoma (PDAC), herein, spatial transcriptomics and proteomics of human surgical samples are applied to select PDAC targets. …”
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