The evolution of personalized medicine: literature review by I. S. Dolgopolov, M. Yu. Rykov

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Unveiling the mechanism of micro-and-nano plastic phytotoxicity on terrestrial plants: A comprehensive review of omics approaches by Asad Jamil, Ambreen Ahmad, Muhammad Moeen-ud-din, Yihao Zhang, Yuxuan Zhao, Xiaochen Chen, Xiaoyu Cui, Yindong Tong, Xianhua Liu

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Proteomic Analysis of Lung Tissue in a Rat Acute Lung Injury Model: Identification of PRDX1 as a Promoter of Inflammation by Dongdong Liu, Pu Mao, Yongbo Huang, Yiting Liu, Xiaoqing Liu, Xiaoqing Pang, Yimin Li

“…To obtain global protein expression changes in acute lung injury (ALI) lung tissues, we employed a high-throughput proteomics method to identify key components which may be involved in the pathogenesis of ALI. …”
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Proteomic analysis of egg production peak and senescence in the ovaries of Taihe black-boned silky fowl (Gallus gallus domesticus Brisson) by Xuan Huang, Shibao Li, Yuting Tan, Chunhui Xu, Yunyan Huang, Zhaozheng Yin

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Proteomic Approach Using DIA-MS Identifies Morphogenesis-Associated Proteins during Cardiac Differentiation of Human iPS Cells by Takaya Urasawa, Nana Kawasaki

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Autophagy is involved in the toxicity of the biocontrol agent GC16 against Tetranychus pueraricola (Acari: Tetranychidae) based on transcriptomic and proteomic analyses by Yanyan He, Guangzu Du, Guang Wang, Huiming Guan, Shusheng Zhu, Bin Chen, Xiahong He, Youyong Zhu

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Whole transcriptomic and proteomic analyses of an isogenic M. tuberculosis clinical strain with a naturally occurring 15 Kb genomic deletion. by Carla Duncan, Frances B Jamieson, JoLynn Troudt, Linda Izzo, Helle Bielefeldt-Ohmann, Angelo Izzo, Carolina Mehaffy

“…Here we subjected these isogenic strains to transcriptomic (via RNA-seq) and proteomic analyses and identified several gene clusters with differential expression in the natural mutant, including the DosR regulon and the molybdenum cofactor biosynthesis genes, both of which were found in lower abundance in the natural mutant. …”
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Utilizing the subtractive proteomics approach to design ensemble vaccine against Candida lusitaniae for immune response stimulation; a bioinformatics study. by Habiba Naz, Rimsha Timotheous, Muhammad Farhan Sarwar, Tariq Nadeem, Mudassar Fareed Awan, Sajed Ali, Sophia Awais, Irfan Ahmed

“…Furthermore, the whole proteome (WP) vaccine was constructed accordingly. …”
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In vitro Effect of Low-level Lasers on Proteomic Concentration in Human Blood Plasma Using 375 nm and 650 nm Lasers by Ahmed Abdulkareem Al-Kaabi, Mustafa Al-Mosawi, Ali Abdullateef Abdulateef Al-Bayati

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Potential Functions and Causal Associations of GNLY in Primary Open-Angle Glaucoma: Integration of Blood-Derived Proteome, Transcriptome, and Experimental Verification by Wang D, Pu Y, Gao X, Zeng L, Li H

“…This study aimed to identify potential causative genes involved in the development of POAG.Methods: We utilized multi-dimensional high-throughput data, integrating proteome-wide association study(PWAS), transcriptome-wide association study (TWAS), and summary data-based Mendelian randomization (SMR) analysis. …”
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Dynamic Proteomic Analysis of Pancreatic Mesenchyme Reveals Novel Factors That Enhance Human Embryonic Stem Cell to Pancreatic Cell Differentiation by Holger A. Russ, Limor Landsman, Christopher L. Moss, Roger Higdon, Renee L. Greer, Kelly Kaihara, Randy Salamon, Eugene Kolker, Matthias Hebrok

“…Summarily, we provide evidence that proteomic analysis of supporting tissues such as the pancreatic mesenchyme allows for the identification of potentially important factors guiding hESC to pancreas differentiation.…”
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Proteomic Analysis of the Murine Liver Response to Oral Exposure to Aflatoxin B1 and Ochratoxin A: The Protective Role to Bioactive Compounds by Silvia Trombetti, Alessandra Cimbalo, Michela Grosso, Pilar Vila-Donat, Jordi Mañes, Lara Manyes

Subjects: “…proteomics…”
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Multi-tissue characterization of the constitutive heterochromatin proteome in Drosophila identifies a link between satellite DNA organization and transposon repression. by Ankita Chavan, Lena Skrutl, Federico Uliana, Melanie Pfister, Franziska Brändle, Laszlo Tirian, Delora Baptista, Dominik Handler, David Burke, Anna Sintsova, Pedro Beltrao, Julius Brennecke, Madhav Jagannathan

“…Here, we use 2 satellite DNA-binding proteins, D1 and Prod, as baits to characterize the chromocenter-associated proteome in Drosophila embryos, ovaries, and testes through quantitative mass spectrometry. …”
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Label-free proteomic analysis of Duchenne and Becker muscular dystrophy showed decreased sarcomere proteins and increased ubiquitination-related proteins by Juliana Cristina Tobar da Silva, Mariângela Rangel Alves Nogueira, Yara Martins da Silva, Fábio César Sousa Nogueira, Nathalie Henriques Silva Canedo, Katia Carneiro, Denise de Abreu Pereira

“…The human phenotypes most related to the proteomic signature were abnormal circulating metabolites, muscle physiology, and weakness. …”
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Proteomic profiling of Labeo rohita intestine infected with Edwardsiella tarda: Unveiling the mucosal defense mechanisms, cell adhesion, and cytoskeletal pathways by Nevil Pinto, Mehar Un Nissa, Gowhar Iqbal, Yashwanth BS, Darshan P, Sanjeeva S, Mukunda Goswami

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Metabolomic and proteomic profiling of a burn-hemorrhagic shock swine model reveals a metabolomic signature associated with fatal outcomes by Bin Wei, Jinguang Zheng, Jiake Chai, Jianxiang Huang, Hongjie Duan, Shaofang Han, Xiaolin Yang, Wenjia Zhang, Fangchao Hu, Yirui Qu, Xiangyu Liu, Tian Liu, Yushou Wu, Yunfei Chi

“…Serum samples collected at 0 h and 2 h post-injury were analyzed using metabolomic and proteomic measurements. The metabolomic and proteomic data were processed through partial least squares–discriminant analysis (PLS–DA) and the KEGG enrichment etc. …”
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A Proteomics Analysis to Evaluate Cytotoxicity in NRK-52E Cells Caused by Unmodified Nano-Fe3O4 by Yi-Reng Lin, Chao-Jen Kuo, Hugo You-Hsien Lin, Chin-Jen Wu, Shih-Shin Liang

“…We cultured NRK-52E cell lines (rat, kidney) and treated with Fe3O4 NPs to investigate and evaluate the cytotoxicity of NPs for NRK-52E cells. Through global proteomics analysis using dimethyl labeling techniques and liquid phase chromatography coupled with a tandem mass spectrometer (LC-MS/MS), we characterized 435 proteins including the programmed cell death related proteins, ras-related proteins, glutathione related proteins, and the chaperone proteins such as heat shock proteins, serpin H1, protein disulfide-isomerase A4, endoplasmin, and endoplasmic reticulum resident proteins. …”
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Enhanced proteomic profiling of human plasma‐derived extracellular vesicles through charge‐based fractionation to advance biomarker discovery potential by Xianyi Su, Getúlio Pereira de Oliveira Júnior, Anne‐Lise Marie, Michal Gregus, Amanda Figueroa‐Navedo, Ionita C. Ghiran, Alexander R. Ivanov

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Exploring the molecular mechanisms of tirzepatide in alleviating metabolic dysfunction-associated fatty liver in mice through integration of metabolomics, lipidomics, and proteomics by Jinliang Liang, Huanyi Liu, Guo Lv, Xiaotong Chen, Zhaoshou Yang, Kunhua Hu, Hongyan Sun

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Synovial Fluid Cell Proteomic Analysis Identifies Upregulation of Alpha-Taxilin Proteins in Rheumatoid Arthritis: A Potential Prognostic Marker by Ashish Sarkar, Shivani Sharma, Prachi Agnihotri, Tanmoy Sarkar, Pooja Kumari, Rajesh Malhotra, Barun Datta, Vijay Kumar, Sagarika Biswas

“…The present study was undertaken to identify the potential biomarkers from a less explored biological sample such as synovial fluid (SF) cells which is specific for RA and to analyze their functional aspects using proteomic approach. Two-dimensional gel electrophoresis (2-DE) was performed using synovial fluid cells of RA and osteoarthritis (OA) patients, and 7 differentially expressed proteins were identified using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS/MS). …”
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