Repeatability, reproducibility, and the effects of radiotherapy on radiomic features of lowfield MR-LINAC images of the prostate by Parker Anderson, Nesrin Dogan, John Chetley Ford, Kyle Padgett, Garrett Simpson, Radka Stoyanova, Matthew Charles Abramowitz, Alan Dal Pra, Rodrigo Delgadillo

“…Definitive radiotherapy (RT) has been shown to be a successful method of treating prostate cancer (PCa) patients. Through radiomics, a quantitative analysis of medical images, it is possible to adapt treatment early on, which may prevent or mitigate future adverse events. …”
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PZS‐Net: Incorporating of Frame Sequence and Multi‐Scale Priors for Prostate Zonal Segmentation in Transrectal Ultrasound by Jianguo Ju, Qian Zhang, Pengfei Xu, Tiange Liu, Cheng Li, Ziyu Guan

“…Accurate prostate zonal segmentation in TRUS videos is vital for diagnosing prostate cancer and guiding surgery. However, TRUS videos are manually recorded by urologists, resulting in no standardized coordinate system, which limits direct prostate zonal segmentation in these videos. …”
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Concurrent Viewing of H&E and Multiplex Immunohistochemistry in Clinical Specimens by Larry E. Morrison, Tania M. Larrinaga, Brian D. Kelly, Mark R. Lefever, Rachel C. Beck, Daniel R. Bauer

“…<b>Results:</b> Application is made to several clinically relevant specimens, including breast cancer (HER2, ER, and PR), prostate cancer (PSMA, P504S, basal cell, and CD8), Hodgkin’s lymphoma (CD15 and CD30), and melanoma (LAG3). …”
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Correlation between oxygen reserve index monitoring and blood gas oxygen values during anesthesia in robotic total prostatectomy surgery by Hilal Zengin

“…Materials and methods The study was carried out with adult male patients over the age of 18 who underwent RARP with the diagnosis of prostate cancer. An ORI pulse oximeter was additionally attached to their index fingers for ORI monitoring. …”
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The accuracy of ultrasensitive PSA in predicting disease progression after radical prostatectomy by Heikki Seikkula, Jaakko Hyysalo, Mikael Högerman, Peter J. Boström, Otto Ettala

“…Results In a cohort with a median age of 64, primarily featuring Gleason score 7 prostate cancer. uPSA nadir of 0.01 ng/ml (AUC = 0.80) at the first monitoring post‐surgery emerged as the optimal cut‐off for identifying subjects at low (80%) or high (20%) risk of BCR within the first 3 years. …”
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Diagnosis and clinical significance of prostate calcification using computed tomography by Seong Cheol Kim, Tae Young Lee, Woocheol Kang, Hoyoung Bae, Ji Hyung Yoon, Sungchan Park, Kyung Hyun Moon, Sang Hyeon Cheon, Taekmin Kwon

“…After applying exclusion criteria (prostate cancer, post-prostatectomy, indwelling urethral catheter, severe artifacts, and software errors), 4,805 patients were included in the final analysis. …”
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Imply on diagnosis and early prognosis of preoperative [68Ga]Ga-PSMA-11 PET/CT in patients with suspected brain tumours of glial origin by K. Pełka, K. Koczyk, L. Koperski, T. Dziedzic, A. Nowak, L. Królicki, P. Kunert, J. Kunikowska

“…Abstract PET/CT targeting prostate-specific membrane antigen (PSMA) is commonly used in patients with prostate cancer. PSMA has been found in other solid tumours, including primary brain tumours. …”
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Qualitative analysis of patients’ feedback from a PROMs survey of cancer patients in England by Richard Wagland, Jessica Corner, Adam Glaser, Sir Mike Richards

“…Objective This study examined how free-text comments from cancer survivors could complement formal patient-reported outcome measures (PROMs), as part of the England PROMs survey programme for cancer.Design A qualitative content analysis was conducted of responses to a single open-ended free-text question placed at the end of the cross-sectional population-based postal questionnaire.Setting Individuals were identified through three UK Cancer Registries and questionnaires were posted to their home addresses.Participants A random sample of individuals (n=4992) diagnosed with breast, colorectal, non-Hodgkins lymphoma or prostate cancer at 1, 2, 3 and 5 years earlier.Results 3300 participants completed the survey (68% response rate). …”
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ENDOPROSTHESIS OF THE SHOULDER JOINT IN METASTATIC LESIONS OF THE PROXIMAL HUMERUS DURING IMMUNOSUPPRESSIVE THERAPY by M. V. Ivanova, V. Yu. Karpenko, A. V. Bukharov, V. A. Derzhavin

“…Metastatic lesions of long bones occurs 2-4 times more common than primary tumors and often are diagnosed with breast cancer in 65–73%, of prostate cancer in 56–68% and lung cancer in 30–36% of patients. …”
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<i>shp-2</i> gene knockout upregulates CAR-driven cytotoxicity of YT NK cells by V. G. Subrakova, S. V. Kulemzin, T. N. Belovezhets, A. N. Chikaev, N. A. Chikaev, O. A. Koval, A. A. Gorchakov, A. V. Taranin

“…We demonstrate that the combination of shp-2 gene knockout and CAR expression increases the cytotoxicity of effector NK-like YT cells against human prostate cancer cell line Du-145 with ectopic expression of PSMA protein, which is specifically targeted by the CAR.…”
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Synthesis of bioactive quinazolin-4(3H)-one derivatives via microwave activation tailored by phase-transfer catalysis by El-Badry Yaser A., El-Hashash Mahr A., Al-Ali Khalil

“…The screened compounds exhibited a significant antitumor activity on some of the cancer cell lines, melanoma (SK-MEL-2), ovarian cancer (IGROV1), renal cancer (TK-10), prostate cancer (PC-3), breast cancer (MCF7) and colon cancer (HT29). …”
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Comparative analysis of lactaptin activity when produced in bacterial or eukaryotic expression systems by O. A. Koval, O. Y. Volkova, A. A. Gorchakov, S. V. Kulemzin, A. V. Tkachenko, A. A. Nushtaeva, E. V. Kuligina, V. A. Richter, A. V. Taranin

“…Next, we measured the cytotoxic effects of the media conditioned by pEL1-transfected HEK293T cells, as assayed against the panel of three human cancer cell lines: MDA-MB-231 (adenocarcinoma), PC3 (prostate cancer), and T98G (glioblastoma). We show that EL1-derived lactaptin is at least 100-fold more cytotoxic than RL2. …”
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Histopathologic Outcomes of Robotic Radical Prostatectomy by Vipul R. Patel, Sagar Shah, David Arend

“…Robotically assisted laparoscopic radical prostatectomy is a minimally invasive alternative for the treatment of prostate cancer. We report the histopathologic and shortterm PSA outcomes of 500 robotic radical prostatectomies. …”
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Association of a Common Variant at 10q26 and Benign Prostatic Hyperplasia Aggressiveness in Han Chinese Descent by Xin Gu, Tao Huang, Ding Xu, Liujian Duan, Yang Jiao, Jian Kang, S. Lilly Zheng, Jianfeng Xu, Jielin Sun, Jun Qi

“…Recent studies reported that rs2252004 at 10q26 was significantly associated with prostate cancer (PCa) risk in a Japanese population and was subsequently confirmed in a Chinese population. …”
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Radiochemistry and Preclinical PET Imaging of Ga-Desferrioxamine Radiotracers Targeting Prostate-Specific Membrane Antigen by Eleni Gourni PhD, Luigi Del Pozzo BSc, Mark Bartholomä PhD, Yvonne Kiefer BSc, Philipp T. Meyer MD, PhD, Helmut R. Maecke PhD, Jason P. Holland D.Phil

“…Radiotracers incorporating the urea-based Glu-NH-C(O)-NH-Lys group have gained prominence due to their role in targeting prostate-specific membrane antigen (PSMA)—a clinical biomarker of prostate cancer. Here, the synthesis, radiolabeling, and in vitro and in vivo characterization of two 68 Ga-radiolabeled Glu-NH-C(O)-NH-Lys radiotracers conjugated to the desferrioxamine B (DFO) chelate were evaluated. …”
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Targeted inhibition of ferroptosis in bone marrow mesenchymal stem cells by engineered exosomes alleviates bone loss in smoking-related osteoporosis by Yao Wang, Lin Sun, Zhenglin Dong, Tianyu Zhang, Leining Wang, Yihui Cao, Hui Xu, Chenglei Liu, Bo Chen

“…Using genetic engineering techniques, we introduced α-1,3-fucosyltransferase 6 (Fut6), a key protein involved in prostate cancer bone metastasis, and identified exosomes expressing Fut6 (F6-exo) with bone-targeting capabilities. …”
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Comparison of User-Directed and Automatic Mapping of the Planned Isocenter to Treatment Space for Prostate IGRT by Zijie Xu, Ronald Chen, Andrew Wang, Andrea Kress, Mark Foskey, An Qin, Timothy Cullip, Gregg Tracton, Sha Chang, Joel Tepper, Di Yan, Edward Chaney

“…The purpose of this study was to retrospectively compare a fully automatic approach, including a non-rigid step, against a user-directed rigid method implemented in a clinical IGRT protocol for prostate cancer. Isocenters resulting from automatic and clinical mappings were compared to reference isocenters carefully determined in each tCT. …”
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Influence of Melatonin on the Proliferative and Apoptotic Responses of the Prostate under Normal and Hyperglycemic Conditions by Marina G. Gobbo, Nishtman Dizeyi, Per-Anders Abrahamsson, Per-Anders Bertilsson, Viviane Sanches Masitéli, Eloisa Zanin Pytlowanciv, Sebastião R. Taboga, Rejane M. Góes

“…The antitumor properties of melatonin (MLT) are known for prostate cancer cells. This study investigated whether MLT affects prostate maturation and interferes with tissue injuries induced by diabetes. …”
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Radiocobalt-Labeling of a Polypyridylamine Chelate Conjugated to GE11 for EGFR-Targeted Theranostics by Lorraine Gaenaelle Gé, Mathias Bogetoft Danielsen, Aaraby Yoheswaran Nielsen, Mathias Lander Skavenborg, Niels Langkjær, Helge Thisgaard, Christine J. McKenzie

“…The overexpression of the epidermal growth factor receptor (EGFR) in certain types of prostate cancers and glioblastoma makes it a promising target for targeted radioligand therapy. …”
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PROTON RADIATION THERAPY: CLINICAL APPLICATION OPPORTUNITIES AND RESEARCH PROSPECTS by M. V. Zabelin, V. A. Klimanov, J. J. Galyautdinova, A. S. Samoilov, A. O. Lebedev, E. V. Shelyhina

“…The available results of the retrospective analysis of clinical data in the University medical center of Lome Linda, testify to advantages of proton therapy of the localized prostate cancer. The lack of a biochemical recurrence and a local tumoral progression within 5 years after radiation was shown. …”
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