Genetic variability and performance of Asian swamp eel Monopterus albus (Zuiew, 1793) from West Java cultured in saline water medium by Dinar Tri Soelistyowati, Ahmad Fahrul Syarif, Ridwan Affandi, Dendi Hidayatullah

“…ABSTRACT   Asian swamp eel Monopterus albus (Zuiew, 1793) is freshwater fish species which is prospective for domestic and export markets. The production is limited depend on the catches of natural population. …”
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Phase II trial of nab-paclitaxel plus ramucirumab in combination with nivolumab for unresectable advanced or recurrent gastric cancer after progression on first-line treatment incl... by Hidekazu Hirano, Naoki Takahashi, Yusuke Amanuma, Nobumi Suzuki, Daisuke Takahari, Takeshi Kawakami, Chie Kudo-Saito, Kengo Nagashima, Narikazu Boku, Ken Kato, Hirokazu Shoji

“…Methods The PADDLE trial, which is sponsored by Ono Pharmaceutical, is an investigator-initiated, multicenter, open-label, single-arm, prospective phase II trial conducted at six institutions in Japan. …”
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Evaluating the Benefit of Home Support Provider Services for Positive Airway Pressure Therapy in Patients With Obstructive Sleep Apnea: Protocol for an Ambispective International R... by Sarah Alami, Manuella Schaller, Sylvie Blais, Henry Taupin, Marta Hernández González, Frédéric Gagnadoux, Paula Pinto, Irene Cano-Pumarega, Lieven Bedert, Ben Braithwaite, Hervé Servy, Stéphane Ouary, Céline Fabre, Fabienne Bazin, Joëlle Texereau

“…Retrospective data, collected during routine patient follow-up by home support providers, include the level of service and device data, notably PAP use. Prospective data collected using an electronic patient-reported outcome tool include health status, OSA-related factors, patient-reported outcomes including quality of life and symptoms, OSA and PAP literacy, patient-reported experience, and satisfaction with PAP therapy and service. …”
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Analisis dan Perancangan Aplikasi Chatbot Menggunakan Framework Rasa dan Sistem Informasi Pemeliharaan Aplikasi (Studi Kasus: Chatbot Penerimaan Mahasiswa Baru Politeknik Astra) by Laksmi Anindyati

“…Chatbot can be an interactive provider of information to prospective students of Polytechnic Astra who are looking information about the registration process or information related to Polytechnic Astra in general. …”
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Production performance of eel Anguilla bicolor bicolor with the addition of calsium carbonat by Ardyen Saputra, Tatag Budiardi, Eddy Supriyono

“…ABSTRACT   Eel have high enough prospects to cultivated. The sustainability of eel culture and overcome slowly growth arising in this cultivation was needed enough information on their biology at growth. …”
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Clinical Outcomes in Diabetic Females Presenting with STEMI: A Cohort Study by Anjana Ajith Beena, Priya Shanmukhan, Veena Felix, Alummoottil George Koshy, Kunjukrishnapilla Sivaprasad

“…Materials and Methods: This was a prospective single-centre cohort study conducted between November 2017 and October 2018 on 204 patients with STEMI and followed-up for three months. …”
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Adherence to a digital therapeutic mediates the relationship between momentary self-regulation and health risk behaviors by Enzo G. Plaitano, Enzo G. Plaitano, Daniel McNeish, Sophia M. Bartels, Sophia M. Bartels, Kathleen Bell, Jesse Dallery, Michael Grabinski, Michaela Kiernan, Hannah A. Lavoie, Hannah A. Lavoie, Shea M. Lemley, Michael R. Lowe, David P. MacKinnon, Stephen A. Metcalf, Stephen A. Metcalf, Lisa Onken, Judith J. Prochaska, Cady Lauren Sand, Cady Lauren Sand, Emily A. Scherer, Luke E. Stoeckel, Haiyi Xie, Lisa A. Marsch

“…Using a novel momentary self-regulation scale, this study examined how targeting self-regulation through a digital therapeutic impacts adherence to the therapeutic and two different health risk behavioral outcomes.MethodsThis prospective interventional study included momentary data for 28 days from 50 participants with obesity and binge eating disorder and 50 participants who smoked regularly. …”
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Evaluation of circulating tumor DNA as a prognostic and predictive biomarker in BRAF V600E mutated colorectal cancer—results from the FIRE‐4.5 study by Susanne Klein‐Scory, Alexander Baraniskin, Wolff Schmiegel, Thomas Mika, Roland Schroers, Swantje Held, Kathrin Heinrich, David Tougeron, Dominik P. Modest, Ingo Schwaner, Jan Eucker, Rudolf Pihusch, Martina Stauch, Florian Kaiser, Christoph Kahl, Meinolf Karthaus, Christian Müller, Christof Burkart, Sebastian Stintzing, Volker Heinemann

“…This study was accompanied by a prospective translational project analyzing cell‐free circulating tumor DNA (ctDNA) in plasma to test whether ctDNA analysis may help to guide clinical treatment decision making. …”
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Redefining outcomes of ventricular arrhythmia for SGLT2 inhibitor medication in heart failure patients: a meta-analysis of randomized controlled trials by Miao Lin, Shiyu Zhang, Lu Zhang, Chengying Yang, Yang Luo, Yajin Peng, Xiaoqiu Tan, Qiang Wen, Xinrong Fan, Xianhong Ou

“…Conclusion SGLT2 inhibitors have beneficial effects on lowering risks of VAs and SCD in patients with type 2 diabetes, cardiovascular diseases, heart failure with reduced ejection fraction (HFrEF), heart failure with preserved ejection fraction (HFpEF), and heart failure with mildly reduced ejection fraction (HFmrEF), with longer follow-up duration reinforcing these findings. However, future prospective trials are needed to verify the effects of SGLT2 inhibitors on VAs and SCD. …”
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Neoadjuvant atezolizumab plus bevacizumab prior liver transplantation for hepatocellular carcinoma by Parissa Tabrizian, Rebecca Marino, Sherrie Bhoori, Marcus Zeitlhoefler, Neil Mehta, Vanessa Banz, Salvatore Gruttadauria, Massimo Iavarone, Chiara Mazzarelli, Nicolò Simonotti, Francis Yao, Vincenzo Mazzaferro, Josep M. Llovet

“…Methods: Herein, we performed a prospective assessment of 17 patients with HCC treated with neoadjuvant preoperative atezolizumab and bevacizumab prior to LT for HCC, obtained from December 2020 and December 2023 at seven Western transplant centers. …”
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The impact of preliminary patient hydration on physiological [18F]PSMA-1007 uptake in the urinary bladder on PET/CT by T. L. Antonevskaya, A. I. Khalimon, O. V. Mukhortova, M. M. Khodzhibekova, A. I. Nikiforuk, D. D. Zubkov, G. F. Khamadeeva, D. Yu. Khodakova, T. N. Lazutina, I. V. Pylova, A. V. Leontyev, I. P. Aslanidi

“…The purpose of this study was to assess the impact of preliminary hydration of patients on [18F]PSMA‑1007 uptake in the urinary bladder.Materials and methods. Prospective, multicenter, randomized controlled study included 180 patients with PCa who underwent [18F]PSMA‑1007 PET/CT. …”
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Utilization of patient-reported outcomes to assess adherence to relugolix when combined with stereotactic body radiation therapy for intermediate to high-risk prostate cancer by Kelly Gaudian, Min Jung Koh, Min Ji Koh, Ryan R. Collins, Shaine Eden, Zoya Zwart, Malika Danner, Alan Zwart, Mark Fallick, Deepak Kumar, Paul Leger, Nancy A. Dawson, Simeng Suy, Sean P. Collins

“…Non-adherence to oral medications due to poor social support or bothersome side effects may increase the risk of cancer recurrence. This prospective study sought to evaluate early testosterone suppression and relugolix drug adherence when combined with prostate stereotactic body radiation therapy (SBRT). …”
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Differences in the Cardiovascular Risk Assessment in Cardiology Outpatients in Mali: Comparison between Framingham Body Mass Index-Based Tool and Low-Information World Health Organ... by Bâ Hamidou Oumar, Sangaré Ibrahima, Camara Youssouf, Sidibé Noumou, Coulibaly Souleymane, Cissoko Yacouba, Sidibé Samba, Konaté Massama, Maiga Asmaou Kéita, Doumbia Coumba Thiam, Touré Mamadou, Diakité Mamadou, Menta Ichaka, Diall Ilo Bella

“…These must be confirmed in further studies and compared to data from prospective studies…”
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Influence of spine biomechanics and sagittal balance on the outcome of lumbar discectomy by José Poblete Carrizo, José Poblete Carrizo, Jesús Martínez, Julio González, Alejandra Mosteiro, Ramon Torné, Ramon Torné, Alberto Di Somma, Alberto Di Somma, José Ríos, Joaquim Enseñat, Joaquim Enseñat, Salvador Fuster, Salvador Fuster

“…The present study explores them as prognostic factors in patients undergoing lumbar microdiscectomy, which could help identify those at higher risk of surgical failure.MethodsProspective analysis of patients treated with lumbar microdiscectomy (n = 52) and healthy control subjects (n = 45) in a single tertiary centre. …”
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Liver Elastography for Liver Fibrosis Stratification: A Comparison of Three Techniques in a Biopsy-Controlled MASLD Cohort by Antonio Liguori, Giorgio Esposto, Maria Elena Ainora, Irene Mignini, Raffaele Borriello, Linda Galasso, Mattia Paratore, Maria Cristina Giustiniani, Laura Riccardi, Matteo Garcovich, Antonio Gasbarrini, Luca Miele, Maria Assunta Zocco

“…<b>Methods:</b> This prospective study included 75 consecutive patients with MASLD who underwent liver biopsy for suspected MASH. …”
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PD-L1/TLR7 dual-targeting nanobody-drug conjugate mediates potent tumor regression via elevating tumor immunogenicity in a host-expressed PD-L1 bias-dependent way by Wei Huang, Ji Zhou, Jia Li, Yakun Wan, Chao Hu, Meng Liu, Pan Xu, Feng Tang, Jianhua Sun, Xiaolu Yu, Yiru Long, Binfan Chen, Yongliang Tong, Mengwen Shan, Xiaomin Jia, Henglei Lu, Runqiu Chen, Jin Ren, Guangyi Jin, Likun Gong

“…Moreover, the efficacy of NDCs is biased toward dependence on host expression of PD-L1.Conclusions The novel PD-L1/TLR7 dual-targeting NDC exhibited potent efficacy against heterogeneous tumors through orchestrating innate and adaptive immunity, which could act as a promising strategy to improve ICB therapy and shows prospects for clinical development.…”
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Efficacy of an avocado-based Mediterranean diet on serum lipids for secondary prevention after ischemic stroke: a randomized phase 2 controlled pilot trial by Verónica V. Olavarría, Paola R. Campodónico, Valeska Vollrath, Paula von Geldern, Carolina Velásquez, Patricia Pavez, Barbara Valente, Pamela Donoso, Alexandra Ginesta, Gabriel Cavada, Enrico Mazzon, Víctor Navia, Matías Guzmán, Pablo Brinck, Andrés Gallardo, Pablo Gonzalez, Pablo M. Lavados

“…Methods The Avocado-Based Mediterranean Diet on Serum Lipids for Secondary Prevention after Ischemic Stroke (ADD-SPISE) was a prospective, randomized, open-label, blinded outcome assessment, phase 2, clinical trial. …”
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Whole lung radiomic features are associated with overall survival in patients with locally advanced non-small cell lung cancer treated with definitive radiotherapy by Meng Yan, Zhen Zhang, Jia Tian, Jiaqi Yu, Andre Dekker, Dirk de Ruysscher, Leonard Wee, Lujun Zhao

“…Methods A total of 661 patients with LA-NSCLC treated with definitive radiotherapy in combination with chemotherapy were enrolled in this study, with 292 patients in the training set, 57 patients from the same hospital from January to December 2017 as an independent test set (test-set-1), 83 patients from a multi-institutional prospective clinical trial data set (RTOG0617) as test-set-2, and 229 patients from a Dutch radiotherapy center as test-set-3. …”
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Virological Aspects of COVID-19 in Patients with Hematological Malignancies: Duration of Viral Shedding and Genetic Analysis by Asma Themlaoui, Massimo Ancora, Kais Ghedira, Yosra Mhalla, Manel Hamdoun, Maroua Bahri, Lamia Aissaoui, Raihane Ben Lakhal, Adriano Di Pasquale, Cesare Camma, Olfa Bahri

“…Coronavirus disease 2019 (COVID-19) has been associated with a significant fatality rate and persistent evolution in immunocompromised patients. In this prospective study, we aimed to determine the duration of excretion of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in 37 Tunisian patients with hematological malignancies (40.5% with lymphoma and 37.8% with leukemia). …”
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Central venous oxygen saturation changes as a reliable predictor of the change of CI in septic shock: To explore potential influencing factors by Ran An, Xi-Xi Wan, Yan Chen, Run Dong, Chun-Yao Wang, Wei Jiang, Li Weng, Bin Du

“…This study aimed to determine the ability of the change in ScvO2 (ΔScvO2) to detect fluid responsiveness in ventilated septic shock patients and potential influencing factors. Methods: In this prospective, single-center study, all patients conducted from February 2023 to January 2024 received fluid challenge. …”
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