Inflammatory burden index as a prognostic marker in patients with advanced gastric cancer treated with neoadjuvant chemotherapy and immunotherapy by Jiao-Bao Huang, Zhi-Yong Zhou, Jun Lu, Ji-Yun Zhu, Bin Lai, Sheng-Xun Mao, Jia-Qing Cao

“…This result still needs to be verified by large prospective studies.…”
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Perceptions of ethical decision-making climate among clinicians working in European and US ICUs: differences between religious and non-religious healthcare professionals by Hanne Irene Jensen, Hans-Henrik Bülow, Lucas Dierickx, Stijn Vansteelandt, Rosanna Vaschetto, Gábor Élö, Ruth Piers, Dominique D. Benoit

“…Methods The study was a cross-sectional analytical observation study as a part of the prospective observational DISPROPRICUS study. A total of 2,275 nurses and 717 physicians from 68 ICUs representing 12 countries in Europe and the US participated. …”
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Effectiveness of Continuous Glucose Monitoring on Short-Term, In-Hospital Mortality Among Frail and Critically Ill Patients With COVID-19: Randomized Controlled Trial by Jiawei Shang, Ziming Yuan, Zuoyan Zhang, Quanhong Zhou, Yan Zou, Wei Wang

“…MethodsThis was an exploratory, prospective, open-label, parallel, single-center, randomized controlled trial. …”
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Application of N-Acetyl-Glucosaminil-N-Acetyl-Muramyl Dipeptide during Triple Component Anti-Helicobacter Pylori Therapy in the Period of Coronavirus Infection COVID-19 by M. R. Konorev, E. N. Tyshevich, R. A. Pavlyukov

“…Aim: evaluation of the incidence of COVID-19 infection after three-component H. pylori eradication therapy while taking N-acetyl-glucosaminyl-N-acetyl-muramyl dipeptide (GMDP).Materials and methods. A prospective randomized comparative clinical study was carried out. …”
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The impact of age on comparative diagnostic accuracy of temporal artery thermometers and non-contact infrared thermometers for fever detection: a systematic review and meta-analysi... by Kwo-Chen Lee, Yun-Ping Lin, Ya-Ling Tzeng, Wen-Chun Liao, Chyi Lo, Pei-Yun Chen, Shu-Hua Lu

“…Methods A systematic review and meta-analysis were conducted, sourcing data from PubMed, MEDLINE, CINAHL, EMBASE, Cochrane Library, ProQuest, and Web of Science. Prospective studies comparing TATs and NCITs against body temperature measurement methods were included. …”
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The relationship between walking speed and changes in cardiovascular risk factors during a 12-day walking tour to Santiago de Compostela: a cohort study by Frank L J Visseren, Yolanda van der Graaf, Wilko Spiering, Remy H H Bemelmans, Paulus P Blommaert, Annemarie M J Wassink, Blai Coll

“…We report the relationship between walking speed and changes in cardiovascular risk factors in participants of a 12-day walking tour to Santiago de Compostela.Design Prospective cohort study.Setting Single-centre study with healthy middle-aged volunteers.Participants Healthy middle-aged men (n=15) and women (n=14). …”
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Efficacy and safety of NeoAdjuvant chemotherapy with or without tIslelizumab followed by debulking surgery for oVarian cancEr (NAIVE study) in China: study protocol of an open-labe... by Ying Zhu, Jianwei Zhou, Zhigang Zhang, Jiaojiao Zhang, Jing Fei, Xiaoqing Zhu

“…The NeoAdjuvant chemotherapy with or without tIslelizumab followed by debulking surgery for oVarian cancEr(NAIVE) study aims to assess the clinical efficacy and safety of NACT in combination with tislelizumab (a monoclonal antibody for programmed cell death protein 1) for advanced EOC.Methods and analysis The NAIVE study is an investigator-initiated, prospective, single-centre, open-label, randomised controlled trial for advanced EOC with the International Federation of Gynaecology and Obstetrics (FIGO) stage IIIc with a Suidan CT score of 3 or greater or a Fagotti laparoscopic score of 8 or greater; or FIGO stage IV. …”
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AI versus human-generated multiple-choice questions for medical education: a cohort study in a high-stakes examination by Alex KK Law, Jerome So, Chun Tat Lui, Yu Fai Choi, Koon Ho Cheung, Kevin Kei-ching Hung, Colin Alexander Graham

“…Objective This study aimed to evaluate the quality and psychometric properties of ChatGPT-4o-generated MCQs compared to human-created MCQs in a high-stakes medical licensing exam. Methods A prospective cohort study was conducted among medical doctors preparing for the Primary Examination on Emergency Medicine (PEEM) organised by the Hong Kong College of Emergency Medicine in August 2024. …”
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Use of Cesarean Birth among Robson Groups 2 and 4 at Mizan-Tepi University Hospital, Ethiopia by Margo S. Harrison, Tewodros Liyew, Ephrem Kirub, Biruk Teshome, Andrea Jimenez-Zambrano, Margaret Muldrow, Teklemariam Yarinbab

“…Methods. This study was a prospective hospital-based cross-sectional analysis of a convenience sample of 1,000 women who delivered at Mizan-Tepi University Teaching Hospital in the summer and fall of 2019. …”
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Genetic Biomarkers and Circulating White Blood Cells in Osteoarthritis: A Bioinformatics and Mendelian Randomization Analysis by Yimin Pan, Xiaoshun Sun, Jun Tan, Chao Deng, Changwu Wu, Georg Osterhoff, Nikolas Schopow

“…<i>CD4</i>, <i>CSF1R</i>, and <i>TYROBP</i> emerge as promising OA biomarkers, meriting further validation in prospective studies.…”
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Intra-operative nasal compression after lateral osteotomy to minimize post-operative Peri-orbital ecchymosis and edema by L. Sowerby, L. M. Kim, W. Chow, C. Moore

“…Objective To determine whether applying direct lateral nasal pressure intraoperatively immediately after performing lateral osteotomies reduces visible post-operative edema and ecchymosis. Methods A prospective, randomized blinded study on consecutive patients undergoing rhinoplasty with lateral osteotomies was conducted in a single academic tertiary care medical center. …”
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Effectiveness of B-actin promoter on driving target gene expression in common carp transgenesis by Andi Aliah Hidayani, Odang Carman, . Alimuddin

“…In fish transgenesis, researcher convinced that use all-fish gene construct is safety and prospective. This study was performed to compare effectiveness b-actin promoter, - the promoter which has ubiquitous, constitutive, housekeeping characteristics, from common carp (homologous) and from tilapia and medaka b-actin promoters (heterologous) in driving of green fluorescent protein (GFP) expression as a model of target gene on common carp transgenesis. …”
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Preterm preeclampsia screening and prevention: a comprehensive approach to implementation in a real-world setting by Stefania Ronzoni, Shamim Rashid, Aimee Santoro, Elad Mei-Dan, Jon Barrett, Nanette Okun, Tianhua Huang

“…This study assesses the feasibility of implementing preterm preeclampsia screening and prevention by leveraging information from our current aneuploidy screening program in a real-world setting with geographic separation clinical site and laboratory analysis site. Methods A prospective cohort study involved pregnant individuals undergoing nuchal translucency scans between 11 and 14 weeks. …”
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The Role of Omega-3 Polyunsaturated Fatty Acids in Patients with Metabolic Syndrome and Endothelial Dysfunction by Andrej Dzupina, Dominik Pella, Pavol Zenuch, Zuzana Zenuchova, Jaipaul Singh, Monika Jankajova, Jan Fedacko

“…<i>Conclusions:</i> The results of this prospective study showed a significant improvement in EF in subjects with MS treated with n-3 PUFAs in a dose of 2.4 g daily.…”
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Thrombotic vs. Bleeding Events of Interruption of Dual Antiplatelet Therapy within 12 Months among Patients with Stent-Driven High Ischemic Risk Definition following PCI by Hao-Yu Wang, Bo Xu, Chen-Xi Song, Chang-Dong Guan, Li-Hua Xie, Yan-Yan Zhao, Zhong-Xing Cai, Sheng Yuan, Ke-Fei Dou

“…This study used data from the Fuwai PCI registry, a large, prospective cohort of consecutive patients who underwent PCI. …”
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Use of flavor capsule cigarettes and their preliminary impact on smoking cessation in Mexico: an exploratory study by Rosibel Rodríguez-Bolaños, Paula Ramírez-Palacios, Katia Gallegos-Carrillo, Arlette Chávez-Iñiguez, Daimarelys Lara, Deborah J. Ossip, Ana Paula Cupertino, Francisco Cartujano-Barrera

“…However, biochemically verified abstinent at Month 3 was higher among participants who smoke FCCs compared to participants who smoke non-FCCs, although the difference was not statistically significant. Prospective and adequately powered comparisons must be made between individuals who smoke FCCs and non-FCCs to effectively assess differences in smoking abstinence, and the reasons for these differences.…”
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A Blueprint for the Problem Formulation Phase of EPA-Type Ecological Risk Assessments for 316(b) Determinations by Webster Van Winkle, William P. Dey, Steve M. Jinks, Mark S. Bevlhimer, Charles C. Coutant

“…Multiple lines of evidence from different levels of analysis, obtained using both prospective and retrospective techniques, provide a broader perspective on the magnitude of potential effects and associated uncertainties and risks. …”
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Serum Soluble Interleukin-2 Receptor Does Not Differentiate Complex Regional Pain Syndrome from Other Pain Conditions in a Tertiary Referral Setting by K. D. Bharwani, M. Dirckx, D. L. Stronks, W. A. Dik, F. J. P. M. Huygen

“…In order to further validate this marker in the diagnostic workup of CRPS, we conducted this prospective cohort study in which we determined sIL-2R levels in patients that were referred to our tertiary referral center with a suspicion of CRPS in a limb, and subsequently compared sIL-2R levels between the patients that were diagnosed with CRPS (CRPS group) and those who were not (no CRPS group). …”
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Factors Associated with Healthcare-Seeking Behavior among Health Profession Students in Selected Universities in Southwestern Uganda. by Wamaani, Hannington Gamukama, Olum, Ronald, Ajuna, Noble, Atwijukire, Humphrey, Kabami, Jane, Asiimwe, John Baptist

“…The link to the questionnaire was sent to prospective participants via WhatsApp platform or email between September and November 2021. …”
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Career Development Programs and Employee Performance in Kanungu District, South Western Uganda by Ainebyona, Alex, Moses, Agaba

“…The findings indicated a Pearson correlation of .0.961** which showed a positive but statistically significant relationship between career planning prospects and employee performance meaning that have personal career plan, providing career advisory services, having career development plan and internal and external programs that develop staff as well as self-assessment tools would result into better employee performance. …”
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