TNG908 is a brain-penetrant, MTA-cooperative PRMT5 inhibitor developed for the treatment of MTAP-deleted cancers by Kimberly J. Briggs, Kevin M. Cottrell, Matthew R. Tonini, Alice Tsai, Minjie Zhang, Douglas A. Whittington, Wenhai Zhang, Steven A. Lombardo, Satoshi Yoda, Erik W. Wilker, Samuel R. Meier, Yi Yu, Teng Teng, Alan Huang, John P. Maxwell

Subjects: “…PRMT5…”
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Inhibitory Effect of PRMT5/MTA Inhibitor on MTAP‐Deficient Glioma May Be Influenced by Surrounding Normal Cells by Yunjie Wang, Xiaohui Sun, Runchen Ma, Xiaofan Zhang, Shengmin Ji, Zhaofeng Liu, Gangqiang Yang, Hongbo Wang, Peng Zhang, Jianzhao Zhang, Jingwei Tian

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Prmt5 is essential for intestinal stem cell maintenance and homeostasis by Li Yang, Xuewen Li, Chenyi Shi, Bing Zhao

Subjects: “…Prmt5…”
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PRMT5 promotes ovarian cancer growth through enhancing Warburg effect by methylating ENO1 by Fei Xie, Han Zhang, Kongkai Zhu, Cheng‐Shi Jiang, Xiaoya Zhang, Hongkai Chang, Yaya Qiao, Mingming Sun, Jiyan Wang, Mukuo Wang, Junzhen Tan, Tao Wang, Lianmei Zhao, Yuan Zhang, Jianping Lin, Chunze Zhang, Shuangping Liu, Jianguo Zhao, Cheng Luo, Shuai Zhang, Changliang Shan

Subjects: “…protein arginine methyltransferase 5 (PRMT5)…”
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