Lactobacillus crispatus S-layer proteins modulate innate immune response and inflammation in the lower female reproductive tract by Alexiane Decout, Ioannis Krasias, Lauren Roberts, Belen Gimeno Molina, Chloé Charenton, Daniel Brown Romero, Qiong Y. Tee, Julian R. Marchesi, Sherrianne Ng, Lynne Sykes, Phillip R. Bennett, David A. MacIntyre

“…Pathogen displacement of vaginal lactobacilli drives innate immune activation and mucosal barrier disruption, increasing the risks of STI acquisition and, in pregnancy, of preterm birth. We describe differential TLR mediated activation of the proinflammatory transcription factor NF-κB by vaginal pathogens and commensals. …”
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Case Report: Respiratory outcome in a preterm infant following previable rupture of membranes and persistent oligohydramnios by Akila Subramanian, Ong Kai Zhi, Arun Kumar Pugalenthi, Arun Kumar Pugalenthi, Arun Kumar Pugalenthi, Arun Kumar Pugalenthi, Victor Samuel Rajadurai, Victor Samuel Rajadurai, Victor Samuel Rajadurai, Victor Samuel Rajadurai, Lay Kok Tan, Suresh Chandran, Suresh Chandran, Suresh Chandran, Suresh Chandran

“…In addition, there is an increased risk of miscarriage, preterm birth, and chorioamnionitis, contributing to septic morbidity in the mother–baby dyad. …”
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Pregnancy and Childbirth Outcomes of Gestational Diabetes Mellitus: A Retrospective Cohort Study by Fatemeh Darsareh, Malihe Shirzadfard Jahromi, Amene Ranjbar, Mitra Shekari, Vahid Mehrnoush, Nasibeh Roozbeh

“…Materials and Methods: To this end, pregnancy and childbirth outcomes were investigated, including the incidence of the need for induction of labor, placenta abruption, preterm birth, intrauterine growth restriction (IUGR), intrauterine fetal death (IUFD), meconium fluid, fetal distress, methods of delivery, perineal lacerations, and postpartum hemorrhage. …”
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Assessment of the hypoglycemic effect of Cyanthillium cinereum (L.) H. Rob. and its dual impact on uterine contraction in gestational diabetic rats by Sasitorn Kerdsuknirund, Arreeya Kosinan, Panida Khunkaewla, Pakanit Kupittayanant, Pattama Tongdee, Porntip Nimkuntod, Susan Wray, Sajeera Kupittayanant

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Pre-IVF treatment with a GnRH antagonist in women with endometriosis (PREGNANT): study protocol for a prospective, double-blind, placebo-controlled trial by Hugh Taylor, Hao Huang, Lubna Pal, Heping Zhang, Howard J Li, Sandra Carson, Valerie Flores, Jared Robbins, Nanette F Santoro, James H Segars, David Seifer, Steven Young

“…Secondary outcomes include oocyte number, fertilisation rate, embryo morphology and implantation rates, as well as rates of known endometriosis-related obstetrical outcomes (pregnancy-induced hypertension, antepartum haemorrhage, caesarean delivery and preterm birth).Ethics and dissemination The PREGnant trial was approved by the Institutional Review Board at Johns Hopkins University. …”
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Associations between use of expressed human milk at 2 weeks postpartum and human milk feeding practices to 6 months: a prospective cohort study with vulnerable women in Toronto, Ca... by Cindy-Lee Dennis, Jane Francis, Alex Kiss, Deborah L O'Connor, Erica Di Ruggiero, Alison Mildon, Stacia Stewart, Bronwyn Underhill, Yi Man Ng, Christina Rousseau, Daniel W Sellen

“…Exclusions: pregnancy loss or participation in prior related study; Study B: preterm birth (<34 weeks); plan to move outside Toronto; not intending to feed human milk; hospitalisation of mother or baby at 2 weeks postpartum.Primary and secondary outcome measures Main exposure variable: any use of expressed human milk at 2 weeks postpartum. …”
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Use of cannabis during pregnancy and birth outcomes in an Aboriginal birth cohort: a cross-sectional, population-based study by Deirdre Gartland, Stephanie J Brown, Karen Glover, Fiona K Mensah, Cathy Leane, Jane Yelland, Jackie Ah Kit, Deanna Stuart-Butler, Donna Weetra, Jonathan Newbury

“…Objectives Indigenous women continue to experience rates of stillbirth, preterm birth and low birth weight, two to three times higher than other women in high-income countries. …”
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Impact of pandemic service changes on ethnic inequalities in maternal and perinatal outcomes in England: a population-based study by Andrew Judge, Erik Lenguerrand, Tim Draycott, Stamatina Iliodromiti, Asma Khalil, Buthaina Ibrahim, Jennifer Elizabeth Jardine

“…Self-reported ethnicity was grouped into White, South-Asian, Black, Mixed and Other.Main outcome measures Composite and component measures of maternal (emergency caesarean section, obstetric anal sphincter injury, hysterectomy, sepsis, anaesthetic complications and prolonged hospital stay) and perinatal (stillbirth, neonatal death, preterm birth, brain injury, small for gestational age and prolonged hospital stay). …”
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Structured lactation support for mothers of very low birthweight preterm infants and establishment of human donor milk banks in German NICUs (Neo-MILK): protocol for a hybrid type... by Angela Kribs, Nicole Ernstmann, Nadine Scholten, Martin Hellmich, Antje Hammer, Eva Mildenberger, Andreas Müller, Dirk Horenkamp-Sonntag, Juliane Köberlein-Neu, Tim Ohnhäuser, Katja Matthias, Jens Ulrich Rüffer, Nicola Gabriela Dymek, Julia Jaschke, Anna Katharina Stirner, Isabella Schwab, Daniel Wiesen, Till Dresbach, Friederike Eyssel, Katharina Lugani, Anne Sunder-Plaßmann, Melanie Klein, Christoph Rupprecht

“…As the production of MOM may be impeded due to preterm birth, it is important to provide lactation support and establish human donor milk (HDM) banks to provide HDM when MOM is fully or initially absent. …”
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Unintended pregnancy among women living with HIV and its predictors in East Africa, 2024. A systematic review and meta-analysis. by Eyob Shitie Lake, Mulat Ayele, Abebaw Alamrew, Befikad Derese Tilahun, Besfat Berihun Erega, Alemu Birara Zemariam, Getinet Kumie, Gizachew Yilak

“…In pregnant women living with HIV and on antiretroviral therapy, preterm birth and low birth weight have been reported. …”
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Maternal and Perinatal Outcome in Women with Systemic Lupus Erythematosus: A Retrospective Bicenter Cohort Study by Sylvia J. Kroese, Carolien N. H. Abheiden, Birgit S. Blomjous, Jacob M. van Laar, Ronald W. H. M. Derksen, Irene E. M. Bultink, Alexandre E. Voskuyl, A. Titia Lely, Marjon A. de Boer, Johanna I. P. de Vries, Ruth D. E. Fritsch-Stork

“…Severe hypertensive disorder of pregnancy, intrauterine fetal death, preterm birth, and small-for-gestational age infants occurred in 18.1%, 4.1%, 32.7%, and 14.8%, respectively. …”
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Scrub typhus in pregnancy: A 10-year multicenter study in resource-limited settings in China. by Peilin Zhao, Tieyong Dong, Hongbin Lu, Rui Zhu, Shanshan Zhao, Wuqian Tao, Li Li, Chunmei Liu, Shuwei Pu, Ling Mo, Huanhuan Wang

“…Over 1/3 (n = 90) had a poor fetal outcome, including 40.0% (n = 36) miscarriage, 23.3% (n = 21) fetal death/stillbirth and 36.7% (n = 33) preterm birth. The use of macrolides reduced the risk of a poor fetal outcome, while lower gestational age (GA) at the time of infection, pneumonia, leucopoenia, thrombocytopenia, and use of chloramphenicol were associated with a poor fetal outcome in univariate logistic-regression analysis, but only lower GA at the time of infection and pneumonia were independent risk factors for a poor fetal outcome on multivariate logistic-regression analysis with an odds ratio of 6.6 (95% CI 2.4-17.8, p < 0.001) and 3.1 (95% CI 1.3-7.6, p = 0.011).…”
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The association between periodontal disease and adverse pregnancy outcomes: a bibliometric analysis from 2000 to 2023 by Miaomiao Zhao, Miaomiao Zhao, Haoxiang Chang, Haoxiang Chang, Yuxu Yue, Yuxu Yue, Xinyue Zeng, Xinyue Zeng, Shaobang Wu, Shaobang Wu, Xiuyun Ren, Xiuyun Ren

“…Adverse pregnancy outcomes (APOs), including preterm birth, small for gestational age infants, gestational diabetes and preeclampsia, are linked to pregnancy complications. …”
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Single, double, and triple-hit strategies to establish a long-term premature rabbit model of bronchopulmonary dysplasia by Chiara Catozzi, Francesca Stretti, Enrica Scalera, Matteo Storti, Angelo Modena, Giorgio Aquila, Gino Villetti, Erica Ferrini, Andrea Grandi, Franco Fabio Stellari, Francesca Ravanetti, Luisa Ragionieri, Roberta Ciccimarra, Matteo Zoboli, Christina Brandenberger, Henri Schulte, Xabier Murgia, Maurizio Civelli, Francesca Ricci

“…Conclusion Several strategies are feasible to extend the preterm rabbit model of BPD to PND14. Preterm birth at the saccular phase itself, even in the absence of other postnatal BPD hits, was associated with lung function deficits, delayed lung development, and cardiovascular abnormalities compared with age-matched term rabbit pups. …”
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Pharmacogenomic screening identifies and repurposes leucovorin and dyclonine as pro-oligodendrogenic compounds in brain repair by Jean-Baptiste Huré, Louis Foucault, Litsa Maria Ghayad, Corentine Marie, Nicolas Vachoud, Lucas Baudouin, Rihab Azmani, Natalija Ivljanin, Alvaro Arevalo-Nuevo, Morgane Pigache, Lamia Bouslama-Oueghlani, Julie-Anne Chemelle, Marie-Aimée Dronne, Raphaël Terreux, Bassem Hassan, François Gueyffier, Olivier Raineteau, Carlos Parras

“…Abstract Oligodendrocytes are critical for CNS myelin formation and are involved in preterm-birth brain injury (PBI) and multiple sclerosis (MS), both of which lack effective treatments. …”
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Anemia during pregnancy and adverse pregnancy outcomes: a systematic review and meta-analysis of cohort studies by Rui Wang, Shan Xu, Xiaoyu Hao, Xingyi Jin, Da Pan, Hui Xia, Wang Liao, Ligang Yang, Shaokang Wang, Shaokang Wang

“…This study aims to explore the relationship between anemia and adverse pregnancy outcomes such as preterm birth, low birth weight, and maternal mortality.MethodsWe conducted both a systematic review and a meta-analysis on the associations between anemia during pregnancy and adverse pregnancy outcomes. …”
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Identification of serum metabolite biomarkers in premature infants with bronchopulmonary dysplasia: protocol for a multicentre prospective observational cohort study by Ping Zhou, Jun Chen, Ying Liu, Cheng Chen, Xin Guo, Zhangbin Yu, Jiebo Liu, Yanping Guo, Dan Dan Rao, Shengnan He, Xudong Yan, Wanxiang He, Songzhou Xu, Ruolin Zhang

“…Introduction Bronchopulmonary dysplasia (BPD) is one of the most common and significant complications of preterm birth. It ultimately leads to a decrease in the quality of life for preterm infants and impacts their long-term health. …”
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Impact of endometrial thickness and its combined effect with maternal age on singleton adverse neonatal outcomes in frozen–thawed embryo transfer cycles by Jie Wang, Jie Wang, Lina Gao, Lina Gao, Qiaoyun Huang, Qiaoyun Huang, Weihua Jiang, Weihua Jiang, Linjun Chen, Linjun Chen, Shanshan Wang, Shanshan Wang

“…The primary outcome was preterm birth (PTB), and the secondary outcome included early PTB (EPTB), small/large for gestational age (SGA/LGA), and low birth weight (LBW).ResultsBaseline characteristics were unevenly distributed across EMT groups. …”
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Diagnostic properties of differing BP thresholds for adverse pregnancy outcomes in standard-risk nulliparous women: A secondary analysis of SCOPE cohort data. by Laura Slade, Maya Blackman, Hiten D Mistry, Jeffrey N Bone, Milly Wilson, Nuhaat Syeda, Lucilla Poston, Peter von Dadelszen, Laura A Magee, SCOPE Consortium

“…Primary outcomes were preterm birth (PTB), low birthweight, postpartum hemorrhage, and neonatal care admission. …”
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Preimplantation genetic testing for aneuploidy in severe male factor infertility: protocol for a multicenter randomised controlled trial by Li Wang, Li Jin, Yao Lu, Chen Zhang, He-Feng Huang, Yun Sun, Xian-hua Lin, Meng-xi Guo, Dan-dan Wu, Jian-lin Zhang, Cheng-liang Zhou, Chen-ming Xu, Song-chang Chen, Song-ying Zhang, Xiao-xi Sun, Yan-ting Wu

“…Secondary outcomes will be embryo implantation rate, biochemical pregnancy rate, clinical pregnancy rate, spontaneous abortion rate, ongoing pregnancy rate, preterm birth rate, fetal chromosomal abnormality rate, birth defect rate and treatment complications. …”
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