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17021
Evolutionary constrained genes associated with autism spectrum disorder across 2,054 nonhuman primate genomes
Published 2025-01-01“…Among macaques, many key ASD-implicated genes were observed to harbour predicted damaging mutations. A small number of key ASD-implicated genes that are highly intolerant to mutation in humans, however, showed no evidence of similar intolerance in macaques (CACNA1D, MBD5, AUTS2 and NRXN1). …”
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17022
Clinical and angiographic profile of left main coronary artery disease in patients with chronic coronary syndrome: a retrospective study
Published 2025-02-01“…We recommend integrating clinical characteristics, and noninvasive investigations as a predictive model of LMD.…”
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17023
Global, regional, and national trends in colorectal cancer burden from 1990 to 2021 and projections to 2040
Published 2025-01-01“…Decomposition and frontier analyses were conducted, and finally, the Bayesian age-period-cohort (BAPC) model was used to predict changes in ASRs up to 2040.ResultsThe GBD 2021 estimates indicate a significant increase in the global incident cases, deaths, and DALYs of CRC from 1990 to 2021. …”
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17024
Integrating microplastic research in sustainable agriculture: Challenges and future directions for food production
Published 2025-06-01“…Furthermore, machine learning algorithms can be employed to analyze complex datasets, enhancing our ability to predict the impacts of MPs on plant health and crop performance under different environmental conditions. …”
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17025
Screening attendance of breast or cervical cancers and its associated factors among 30-49 year old women in Gedeo zone, South Ethiopia: Cross-sectional study.
Published 2025-01-01“…<h4>Objective</h4>To assess the magnitude of screening attendance for breast or cervical cancer, as well as the factors that predict it, among women aged 30-49 years old in Gedeo Zone, South Ethiopia, in 2023.…”
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17026
PAK5 Induces EMT and Promotes Cell Migration and Invasion by Activating the PI3K/AKT Pathway in Ovarian Cancer
Published 2018-01-01“…Higher expression of PAK5 predicted poor survival fates in patients with ovarian cancer (p=0.008). …”
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17027
Clinical Effect and Rotational Stability of TICL in the Treatment of Myopic Astigmatism
Published 2020-01-01“…The results of our study support that TICL implantation is safe, effective, and predictable in the treatment of moderate to high myopic astigmatism, with relatively good postoperative rotational stability.…”
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17028
Association between pan-immune-inflammation value and coronary heart disease in elderly population: a cross-sectional study
Published 2025-02-01“…The receiver operator characteristic (ROC) curve was used to explore the predictive value of PIV combined with COUNT score for CHD.Results41,713 individuals qualified for analysis. …”
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17029
Relation of Wnt Signaling Pathway Inhibitors (Sclerostin and Dickkopf-1) to Left Ventricular Mass Index in Maintenance Hemodialysis Patients
Published 2021-01-01“…Left ventricular hypertrophy (LVH) is common in hemodialysis (HD) patients. It predicts poor prognosis. Several inhibitors regulate Wnt canonical pathways like Dickkopf-related protein-1 (Dkk-1) and sclerostin. …”
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17030
The iGains4Gains model guides irrigation water conservation and allocation to enhance nexus gains across water, food, carbon emissions, and nature
Published 2025-01-01“…Recognising nexus gains are not always linear, positive and predictable, the model reveals that achieving all four gains simultaneously is difficult, likely leading to trade-offs such as water consumption rebounds or increased carbon emissions. …”
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17031
Constructing stellar solutions with spherical symmetry through quadratic anisotropy in f(Q) gravity
Published 2025-01-01“…The $$I-M$$ I - M curve shows greater sensitivity to the stiffness of the equation of state than the $$M-R$$ M - R curve, reinforcing our conclusion about the $$I-M$$ I - M framework’s responsiveness. Finally, we predicted the corresponding radii and moments of inertia for various values of $$\alpha $$ α based on the $$M-R$$ M - R and $$M-I$$ M - I curves.…”
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17032
A Study on Dust Storm Pollution and Source Identification in Northwestern China
Published 2025-01-01“…These findings are significant for understanding and predicting the causes, characteristics, and environmental impacts of dust storms in Lanzhou and the Northwestern region.…”
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17033
Rethinking Conservation and Restoration Strategies of Endangered and Key Medicinal Clavicarpa Plants in Yunnan‐Kweichow Plateau's Karst Areas Under Climate Change
Published 2025-01-01“…To mitigate these threats, the Maxent algorithm was employed to analyze current and future distribution patterns, with a particular focus on the influence of climate variables in predicting potential distribution shifts and assessing extinction risks under the optimistic SSP1‐2.6 and the pessimistic SSP5‐8.5 socioeconomic scenarios. …”
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17034
ChatGPT-4 Performance on German Continuing Medical Education—Friend or Foe (Trick or Treat)? Protocol for a Randomized Controlled Trial
Published 2025-02-01“…Upon analysis of our acquired data, we predict our findings to be ready for publication as soon as early 2025. …”
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17035
Depressive symptoms and quality of life among women experiencing infertility: The moderating effect of perceived social support
Published 2025-01-01“…In this group, depressive symptoms negatively predicted fertility QoL (ß = −.92, p < .05), and a significant interaction effect between depressive symptom severity and social support on fertility QoL was observed (ß = −1.24, p < .05). …”
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17036
Fluid volume status detection model for patients with heart failure based on machine learning methods
Published 2025-01-01“…Four machine learning classification models were used to predict patients' fluid volume status, and their effectiveness was measured using the receiver operating characteristic (ROC) area under the curve (AUC), calibration curve, accuracy, precision, recall, F1 score, specificity, and sensitivity. …”
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17037
Metatranscriptomes-based sequence similarity networks uncover genetic signatures within parasitic freshwater microbial eukaryotes
Published 2025-02-01“…However, the vast amount of data produced by -omics approaches require data-driven methodologies to make predictions about these microorganisms’ role within ecosystems. …”
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17038
EZH2 Mediates miR-146a-5p/HIF-1α to Alleviate Inflammation and Glycolysis after Acute Spinal Cord Injury
Published 2021-01-01“…ChIP verified the enrichment of H3K27me3 in the miR-146a-5p promoter region. Bioinformatics predicted the binding sites of HIF-1α and miR-146a-5p, and dual-luciferase reporter assay verified the binding of HIF-1α and miR-146a-5p. …”
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17039
Association of Plasma Levels of Nitric Oxide Oxidative Metabolites with Acute Stroke in Patients Presenting to the Emergency Department of a Low-Middle Income Country
Published 2019-01-01“…Our objectives were to investigate plasma NOx in patients with acute stroke presenting to the Emergency Department (ED) and to determine if it could (i) differentiate between ischemic and hemorrhagic stroke; (ii) predict clinical outcomes. Methods. A cross-sectional study was conducted in the ED of Aga Khan University Hospital, from January 1 to December 31, 2016. …”
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17040
Automated Essay Scoring Menggunakan Semantic Textual Similarity Berbasis Transformer Untuk Penilaian Ujian Esai
Published 2023-12-01“…Then the similarity value is converted to the desired range of values as the predicted value of each essay. Based on the evaluation results, it was found that the fine-tuned IndoBERT model was the best model, with MAE and RMSE values of 0.1285 and 0.2001. …”
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