Comparative survival outcomes of neoadjuvant and adjuvant therapy in patients with T1c, node-negative, triple-negative breast cancer: A population-based analysis by Yi-Zi Zheng, Jia-Qi Ying, Ting-Ting Wu, Yong-Hui Su, Ou-Chen Wang

“…Logistic regression models were utilized to identify predictive factors for response to NAT. Results: A total of 1033 patient pairs passed the PSM process, resulting in a well-balanced distribution. …”
Get full text

Comparative Evaluation and Measure of Accuracy of ELISAs, CLIAs, and ECLIAs for the Detection of HIV Infection among Blood Donors in China by Le Chang, Junpeng Zhao, Fei Guo, Huimin Ji, Lu Zhang, Xinyi Jiang, Lunan Wang

“…CLIA and ECLIA assay had similar sensitivities with ELISAs but showed higher specificity (CLIA: 99.1%, 885/893; ECLIA: 99.0%, 884/893), concordance rate (CLIA: 99.2%, 1021/1029; ECLIA: 99.1%, 1020/1029), and positive predictive value (PPV) (CLIA: 94.4%, 136/144; ECLIA: 93.8%, 136/145) than most of ELISA kits (>5 ELISAs) (P<0.05). …”
Get full text

Monitoring changes of forest height in California by Samuel Favrichon, Jake Lee, Yan Yang, Yan Yang, Ricardo Dalagnol, Ricardo Dalagnol, Fabien Wagner, Le Bienfaiteur Sagang, Le Bienfaiteur Sagang, Sassan Saatchi, Sassan Saatchi, Sassan Saatchi

“…We train a deep neural network to predict forest height metrics at 10-m resolution from radar and optical satellite imagery. …”
Get full text

Identifying pesticide mixtures at country-wide scale by Cairo, Milena, Monnet, Anne-Christine, Robin, Stéphane, Porcher, Emmanuelle, Fontaine, Colin

“…The consequences of such exposure are still poorly understood, first because of potentially strong synergistic effects, making cocktails effects not predictable from the effects of single compounds, but also because little is known about the actual exposure of organisms to pesticide mixtures in nature. …”
Get full text

Therapeutic target genes and regulatory networks of gallic acid in cervical cancer by Zhixi You, Ye Lei, Yongkang Yang, Zhihui Zhou, Xu Chao, Keyi Ju, Songyi Wang, Yuanyuan Li, Yuanyuan Li

“…Furthermore, the upstream microRNA (miRNA), long noncoding RNA (lncRNA), and circular RNA (circRNA) of the candidate genes were predicted using the online tools of MirDIP, TarBase, and ENCORI. …”
Get full text

Non-Linear Biomechanical Evaluation and Comparison in the Assessment of Three Different Piece Dental Implant Systems for the Molar Region: A Finite Element Study by Jesus Alejandro Serrato-Pedrosa, Ignacio Villanueva-Fierro, Rodrigo Arturo Marquet-Rivera, Rosa Alicia Hernández-Vázquez, Salvador Cruz-Lopez, Verónica Loera-Castañeda

“…This biomechanical approach could provide a promising strategy for predicting micro-strains and micromotion in implant system pieces and geometries. …”
Get full text

Systematic underestimation of type-specific ecosystem process variability in the Community Land Model v5 over Europe by C. Poppe Terán, C. Poppe Terán, C. Poppe Terán, B. S. Naz, B. S. Naz, H. Vereecken, H. Vereecken, R. Baatz, R. A. Fisher, H.-J. Hendricks Franssen, H.-J. Hendricks Franssen

“…</p> <p>Here, we evaluated CLM5's predictions of water and energy fluxes using observations from eddy covariance stations from the Integrated Carbon Observation System (ICOS), remote sensing, and reanalysis data sets. …”
Get full text

Organizational readiness for change towards implementing a sepsis survivor hospital to home transition-in-care protocol by Elaine Sang, Elaine Sang, Ryan Quinn, Michael A. Stawnychy, Michael A. Stawnychy, Michael A. Stawnychy, Michael A. Stawnychy, Jiyoun Song, Jiyoun Song, Jiyoun Song, Karen B. Hirschman, Karen B. Hirschman, Karen B. Hirschman, Sang Bin You, Sang Bin You, Katherine S. Pitcher, Katherine S. Pitcher, Nancy A. Hodgson, Nancy A. Hodgson, Nancy A. Hodgson, Patrik Garren, Melissa O'Connor, Sungho Oh, Sungho Oh, Kathryn H. Bowles, Kathryn H. Bowles, Kathryn H. Bowles, Kathryn H. Bowles

“…Additional studies may assess the predictive validity of ORIC towards implementation success.…”
Get full text

Parameters Suggesting Spontaneous Passage of Stones from Common Bile Duct: A Retrospective Study by Tawfik Khoury, Mohamed Adileh, Ashraf Imam, Yosef Azraq, Avital Bilitzky-Kopit, Muhamad Massarwa, Ari Benson, Zaher Bahouth, Samir Abu-Gazaleh, Wisam Sbeit, Rifaat Safadi, Abed Khalaileh

“…Comparing groups A versus B, only gamma-glutamyl transferase predicted spontaneous passage of stones from CBD, as the level was significantly higher in group A (677±12.1) versus group B (362.4±216.2) (P=0.023). …”
Get full text

Patient-reported outcome measures following surgeries in implant dentistry and associated factors: a cross-sectional study by Xinyu Wu, Qi Yan, Bin Shi, Mengjie Ye, Jiahui Sun, Haibin Xia

“…Similarly, the factors associated with the duration of discomfort included alcohol consumption, pain perception during surgery and age (p&lt;0.05).Conclusions PROMs related to dental implant surgeries can be predicted using certain risk indicators. Alcohol consumption, pain during surgery and age were associated with discomfort following dental implant surgery.…”
Get full text

Screening for schistosomiasis in a non-endemic setting: Accuracy of a rapid antibody test using finger prick blood by Margherita Ortalli, Bianca Granozzi, Michele Bacchiega, Concettina Di Lillo, Greta Roncarati, Silvia Stefania Longoni, Cristina Mazzi, Elisa Vanino, Zeno Bisoffi, Stefania Varani

“…At the estimated prevalence level for the study sample, 32.6 % (25.5–40.0), the positive and negative predictive values were 78.2 % (66.4–89.4) and 93.2 % (87.7–97.6), respectively. …”
Get full text

Rapid identification and phenotyping of nonalcoholic fatty liver disease patients using a machine‐based approach in diverse healthcare systems by Anna O. Basile, Anurag Verma, Leigh Anne Tang, Marina Serper, Andrew Scanga, Ava Farrell, Brittney Destin, Rotonya M. Carr, Anuli Anyanwu‐Ofili, Gunaretnam Rajagopal, Abraham Krikhely, Marc Bessler, Muredach P. Reilly, Marylyn D. Ritchie, Nicholas P. Tatonetti, Julia Wattacheril

“…Clinical chart review identified a high positive predictive value (PPV) across all healthcare systems: 91% at CUIMC, 75% at UPHS, and 85% at VUMC, and a sensitivity of 79.6%. …”
Get full text

RNA m6A-mediated post-transcriptional repression of glucocorticoid receptor in LPS-activated Kupffer cells on broilers by Yulan Zhao, Yidan Jiang, Yue Feng, Ruqian Zhao

“…Subsequently, specific m6A sites on GR were predicted and verified. Mutation m6A sites and luciferase reporter assay was also applied to validate these findings. …”
Get full text

Dynamics and Insights into the Unique Ecological Guild of Fungi in Bacteria-Bioaugmented Anaerobic Digesters by Linda U. Obi, Ashira Roopnarain, Memory Tekere, Jun Zhou, Heng Li, Yuanpeng Wang, Yanlong Zhang, Rasheed A. Adeleke

“…The functional potential of the fungal community was predicted using ecological guild analysis. The dominant fungal phyla were (with relative abundance ≥1%) Ascomycota and Neocallimastigomycota. …”
Get full text

Structural performance of lightweight fibre-reinforced oil palm shell concrete subjected to impact loadings under varying boundary conditions by Idris Ahmed Ja'e, Zakaria Che Muda, Agusril Syamsir, Chiemela Victor Amaechi, Hamad Almujibah, Ali.E.A. Elshekh, Maaz Osman Bashir, Abdulrazak H. Almaliki

“…Regression models were developed to predict responses for specimens with up to 8 boundary conditions and 5 % PPF. …”
Get full text

Understanding the Broad-line Region of Active Galactic Nuclei with Photoionization. I. The Moderate-accretion Regime by Qiaoya Wu, Yue Shen, Hengxiao Guo, Scott F. Anderson, W. N. Brandt, Catherine J. Grier, Patrick B. Hall, Luis C. Ho, Yasaman Homayouni, Keith Horne, Jennifer I-Hsiu Li, Donald P. Schneider

“…We compare theoretical predictions with observations of a sample of 67 z  ≲ 0.5 reverberation-mapped AGNs with rest-frame optical and UV spectra in the moderate-accretion regime (Eddington ratio λ _Edd  ≡  L / L _Edd  < 0.5). …”
Get full text

Unraveling the depth-dependent causal dynamics of methanogenesis and methanotrophy in a high-latitude fen peatland by Shuai Yang, Jinyun Tang, Zhen Li, Kunxiaojia Yuan, Qiong Wu, Kuang-Yu Chang, Suzanne B Hodgkins, Rachel M Wilson, Qing Zhu, Robert F Grant, William J Riley, Scott R Saleska, Virginia I Rich, Ruth K Varner

“…Overall, this research provides important insights into the causal mechanisms modulating CH _4 cycling across different depths, which will improve carbon cycling predictions, and guide the future field measurement strategies.…”
Get full text

Development of an easy non‐destructive particle isolation protocol for quality control of red blood cell concentrates by Marine Ghodsi, Anne‐Sophie Cloos, Anaïs Lotens, Marine De Bueger, Patrick Van Der Smissen, Patrick Henriet, Nicolas Cellier, Christophe E. Pierreux, Tomé Najdovski, Donatienne Tyteca

“…It was reproducible, could predict the number of extracellular vesicles obtained with the 20,000 × g protocol and better discriminated between the three vesiculation cohorts than haemolysis at the legal expiry date of 6 weeks. …”
Get full text

Genome-wide identification of novel flagellar motility genes in Pseudomonas syringae pv. tomato DC3000 by Zichu Yang, Tyler Helmann, Maël Baudin, Maël Baudin, Maël Baudin, Karl J. Schreiber, Karl J. Schreiber, Zhongmeng Bao, Paul Stodghill, Paul Stodghill, Adam Deutschbauer, Adam Deutschbauer, Jennifer D. Lewis, Jennifer D. Lewis, Bryan Swingle, Bryan Swingle

“…Besides many of the known or predicted chemotaxis and motility genes, our method identified PSPTO_0406 (dipA), PSPTO_1042 (chrR) and PSPTO_4229 (hypothetical protein) as novel motility regulators. …”
Get full text

Augmenting neurocognitive remediation therapy to Preventive Cognitive Therapy for partially remitted depressed patients: protocol of a pragmatic multicentre randomised controlled t... by Huibert Burger, Claudi Bockting, Marlies Brouwer, Gert J Geurtsen, Amanda M Legemaat, Johanne G J van der Stappen, Maria Semkovska, Isidoor O Bergfeld, Nicoline Lous, Damiaan A J P Denys

“…Treatment might be more effective if cognitive functioning of patients is targeted as well since cognitive problems are the most persisting symptom in partial remission and predict poor treatment response and worse functioning. …”
Get full text