Plasma Concentrations of Benzylpenicillin and Cloxacillin in Infective Endocarditis—With Special Reference to Delayed Hypersensitivity Reactions by Malin Hägglund, Ulrika Snygg-Martin, Lars Olaison, Michael Stofkoper, Bert Ove Larsson, Magnus Brink

“…TDM might be useful in situations where concentrations are hard to predict, such as severe obesity or kidney failure. …”
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Argonaute2 modulates megakaryocyte development and sex-specific control of platelet protein expression and reactivity by Sophia Lazar, Jeremy G.T. Wurtzel, Shayan Askari, Matthew Cooper, Xuefei Zhao, Peisong Ma, Lawrence E. Goldfinger

“…We generated megakaryocyte/platelet-specific Ago2-deleted (Ago2 KO) mice and assessed proteomic and functional effects. We predicted platelet hyperreactivity with Ago2 deletion due to large-scale upregulated protein expression. …”
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Soil moisture controls over carbon sequestration and greenhouse gas emissions: a review by Yuefeng Hao, Jiafu Mao, Charles M. Bachmann, Forrest M. Hoffman, Gerbrand Koren, Haishan Chen, Hanqin Tian, Jiangong Liu, Jing Tao, Jinyun Tang, Lingcheng Li, Laibao Liu, Martha Apple, Mingjie Shi, Mingzhou Jin, Qing Zhu, Steve Kannenberg, Xiaoying Shi, Xi Zhang, Yaoping Wang, Yilin Fang, Yongjiu Dai

“…The interactive model-experiment framework emerges as a promising approach for linking experimental data with model refinement, enabling continuous improvement of CS-GHG predictions. From a policy perspective, shifting focus from short-term agricultural productivity to long-term carbon sequestration is crucial. …”
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Discovery of conserved peptide-MHC epitopes for directly alloreactive CD8+ T cells by Alexandra E. Hill, Eric T. Son, Moumita Paul-Heng, Chuanmin Wang, Shivanjali Ratnaseelan, Martina Denkova, Pouya Faridi, Asolina Braun, Anthony W. Purcell, Nicole A. Mifsud, Alexandra F. Sharland

“…Peptide abundance across skin, spleen and liver samples (estimated as the product of the spectral intensity obtained for these samples) was the principal factor influencing recognition of peptide-Kd epitopes. Predicted binding affinity (BA score) and overall peptide hydrophobicity were also independently correlated with immunogenicity, while there was no significant correlation between the IEDB immunogenicity score and the proportion of T cells recognising a given epitope. …”
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Primary Fallopian Tube Carcinoma: Results of a Single-Institutional Retrospective Analysis of 17 Patients with Evaluation of Staging and Prognostic Factors by Neserine Tounsi, Hanen Bouazize, Ikram Margheli, Nadia Boujelbene, Hechiche Monia, Maher Slimane, Khaled Rahel

“…In our study, only the residual tumor was a significant prognostic factor predicting survival. CONCLUSION: Complete optimal surgery with no residual tumor was the main goal of the surgeon to improved survival in primary fallopian tube carcinoma. …”
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Determinants of Deescalation Failure in Critically Ill Patients with Sepsis: A Prospective Cohort Study by Nawal Salahuddin, Lama Amer, Mini Joseph, Alya El Hazmi, Hassan Hawa, Khalid Maghrabi

“…On multivariate regression analysis, failure to deescalate was significantly predicted by hematologic malignancy OR 3.3 (95% CI 1.4–7.4) p<0.004, fungal sepsis OR 2.7 (95% CI 1.2–5.8) p=0.011, multidrug resistance OR 2.9 (95% CI 1.4–6.0) p=0.003, baseline serum procalcitonin OR 1.01 (95% CI 1.003–1.016) p=0.002, and SAPS II scores OR 1.01 (95% CI 1.004–1.02) p=0.006. …”
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The associations between diet-induced inflammation and the improvement or worsening of hepatic steatosis and fibrosis: a longitudinal analysis of RaNCD cohort study by Mohammad Sedighi, Amir Saber, Amir Bagheri, Saba Hazratian, Yahya Pasdar, Farid Najafi, Mehdi Moradinazar, Davood Soleimani

“…The AST to platelet ratio index (APRI) and Fibrosis-4 (FIB-4) were used as confirmed predictive indicators for hepatic fibrosis and the hepatic steatosis index (HSI) was used for hepatic steatosis. …”
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Impact of gender on the prognosis of carotid body tumor after surgical resection by Huanrui Hu, Yuwei Xiang, Bin Huang, Ding Yuan, Yi Yang, Jichun Zhao

“…Tumor size and Shamblin classification cannot predict the overall survival rate of patients with excised CBTs. …”
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ThermalGS: Dynamic 3D Thermal Reconstruction with Gaussian Splatting by Yuxiang Liu, Xi Chen, Shen Yan, Zeyu Cui, Huaxin Xiao, Yu Liu, Maojun Zhang

“…Experimental results demonstrate that the proposed method achieves state-of-the-art performance on the TSDN dataset, with an average absolute temperature error of 1 °C and the ability to predict surface temperature variations over time.…”
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Allelic and epigenetic DNA variation in relation to F1 heterosis manifestation in F1 hybrids of Capsicum annuum L. by M. N. Shapturenko, S. V. Vakula, L. A. Tarutina, T. V. Nikitinskaya, T. V. Pechkovskaya, L. A. Mishin, L. V. Khotyleva

“…According to our data, the total number of polymorphic SSR loci and the ratio of polymorphic and nonpolymorphic loci demonstrate a significant predictive value and can serve as additional prognostic criteria for the selection of promising cross-combinations. …”
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Factors Associated with Mortality in Severe Acute Cholangitis in a Moroccan Intensive Care Unit: A Retrospective Analysis of 140 Cases by Soumaya Touzani, Abderrahim El Bouazzaoui, Fatima Bouyarmane, Kaoutar Faraj, Nawfal Houari, Brahim Boukatta, Nabil Kanjaa

“…Moreover, as multiple organ failure is often associated with mortality in severe acute cholangitis, predictive risk factors of organ failure should be more investigated.…”
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Membrane-bound model of the ternary complex between factor VIIa/tissue factor and factor X by Melanie P. Muller, Alex Mortenson, Josepha C. Sedzro, Po-Chao Wen, James H. Morrissey, Emad Tajkhorshid

“…Rigid-body docking generated 1 000 000 protein-only structures that predict the binding of key EC domains. Residue-residue contact information was then used in nonequilibrium simulations to drive the formation of the EC on a phosphatidylserine/phosphatidylcholine membrane surface, providing, to our knowledge, the first membrane-bound model for the EC. …”
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Furanocoumarin compounds isolated from Dorstenia foetida potentiate irinotecan anticancer activity against colorectal cancer cells by Pengnam Supusson, Jitkaroon Watcharapa, Srisuphan Roongtiwa, Wongprayoon Pawaris, Rayanil Kanok-On, Charoensuksai Purin

“…The simulation revealed that, at the molar ratio of Iri:2 of 1:40, the concentration predicted to achieve a 90 % inhibitory effect when used in the combination would be ~28- and ~4-fold lower than the concentration of compound 2 and Iri, resp., when used individually. …”
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Temporal Changes on the Risks and Complications of Posttransplantion Diabetes Mellitus Following Cardiac Transplantation by Nadia Iannino, Amine Nasri, Agnès Räkel, Anique Ducharme, Kim Lachance, Normand Racine, Simon de Denus, Maxime Tremblay-Gravel, Annik Fortier, Michel White

“…Independent risk factors predicting PTDM at one year were recipient’s age, duration of cold ischemic time, treatment with furosemide, and tacrolimus. …”
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Preoperative neck ultrasound combined with pathological data can significantly impact the outcome of medullary thyroid carcinoma by Maurilio Deandrea, Tommaso Piticchio, Alberto Mormile, Francesca Retta, Giovanni Canale, Alessandra Caracciolo, Lorenzo Daniele, Pierpaolo Trimboli

“…Preoperative neck US can significantly help to predict MTC outcome.…”
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Modern advancements of energy storage systems integrated with hybrid renewable energy sources for water pumping application by Marwa M. Ahmed, Haneen M. Bawayan, Mohamed A. Enany, Mahmoud M. Elymany, Ahmed A. Shaier

“…The manuscript also highlights the integration of artificial intelligence (AI) to optimize energy management, predict irrigation demands, and improve operational efficiency. …”
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Transforming 5G Mega-Constellation Communications: A Self-Organized Network Architecture Perspective by Marius Corici, Marius Caus, Xavier Artiga, Alessandro Guidotti, Benjamin Barth, Tomaso de Cola, Justin Tallon, Hemant Zope, Daniele Tarchi, Fanny Parzysz, David Naseh, Swapnil Sadashiv Shinde

“…These constellations are already equipped with inter-satellite links and adaptable payloads capable of supporting Radio Access Network (RAN) and core network functionalities, forming complex space-based networks characterized by overlapping layers of multi-orbit, grid-like topologies that undergo continuous, yet predictable, changes&#x2014;peculiarities not currently addressed within the 5G standards framework. …”
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Multimessenger Probes of Supermassive Black Hole Spin Evolution by Angelo Ricarte, Priyamvada Natarajan, Ramesh Narayan, Daniel C. M. Palumbo

“…The data also clearly prefer models with coherent accretion over models in which accretion disks rapidly switch from prograde to retrograde. We further predict spin distributions accessible via spatially resolved event horizons by the next-generation Event Horizon Telescope and Black Hole Explorer, as well as gravitational waves by the Laser Interferometer Space Antenna (LISA), each of which offers unique and distinct windows into the population of spinning BHs. …”
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Projection of glacier changes over the Laohugou Glacier No. 12, Northeast Tibetan Plateau, China from 2020 to 2100 by Mengyuan Liu, Baojuan Huai, Lei Wang, Yuzhe Wang, Hongmin An, Jizu Chen, Wentao Du, Xiang Qin, Weijun Sun

“…Based on the Coupled Model Intercomparison Project (CMIP6) models, the degree-day and glacier retreat models were used to predict the glacier changes under three scenarios for 2020–2100. …”
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In Vivo Evaluation of the Combined Anticancer Effects of Cisplatin and SAHA in Nonsmall Cell Lung Carcinoma Using [18F]FAHA and [18F]FDG PET/CT Imaging by Skye Hsin-Hsien Yeh, Ming Hsien Lin, I. I. Leo Garcia Flores, Uday Mukhopadhyay, Danial Young, Kazuma Ogawa, Jeong-Hwan Jeong, William Tong, Juri G. Gelovani, Nobuyoshi Fukumitsu

“…Detection of changes in HDAC activity/expression may provide important prognostic and predictive information and influence treatment decision-making. …”
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