Clinical utility of tumour mutational burden on efficacy of immune checkpoint inhibitors in malignant solid tumours: protocol for a systematic review and meta-analysis by Xiaoguang Yang, Yunming Li, Xuemei Xiang, Wang Guo, Pengfei Zhou

“…We propose a systematic review to evaluate the predictive value of tumour mutation burden (TMB) on efficacy of ICIs.Methods and analysis A systematic literature search will be conducted in the PubMed, OVID, Web of Science, Embase and Cochrane Central Register of Controlled Trials Library databases up to 31 May 2022. …”
Get full text

Wastewater-based epidemiology for novel Coronavirus detection in wastewater by G. Saini, P. Deepak

“…This technique relies on collecting and testing samples from sewers and/or wastewater treatment plants for the presence of pathogens and then using that data to determine and predict the spread of the infection, thereby allowing the provision of appropriate containment and treatment steps. …”
Get full text

Leaflet: Operative Steps for Interventional Studies in Neuroscience by Maria Meringolo, Sergio Delle Monache, Giuseppina Martella, Antonella Peppe

“…Notably, neuroscience drug development encounters distinct challenges, including the complex nature of diseases, limitations imposed by the blood–brain barrier, the absence of reliable predictive preclinical models, and regulatory hurdles. …”
Get full text

Optimal Embryo Selection: The Irreplaceable Role of the Embryologist in an Age of Advancing Technology by Lauren Kendall Rauchfuss, Yulian Zhao, David Walker, Terri Galantis, Jolene Fredrickson, Kathrynne Barud, Chandra Shenoy

“…Results: Morphological and morphokinetic grading were both predictive of embryo competence on days 3 and 5. However, on day 3, morphologic grading was superior to morphokinetic grading with area under the curve (AUC) of 0.66 (P < 0.001) and 0.58 (P = 0.009), respectively. …”
Get full text

Ecological niche modeling of invasive alien plant species in a protected landscape by G.C.B. Paclibar, E.R. Tadiosa

“…Lastly, the MaxEnt model exemplifies that the most suitable predicted conditions for invasive alien plant species are at the edges of boundary and buffer zones. …”
Get full text

Health impact of work stressors and psychosocial perceptions among French hospital workers during the COVID-19 outbreak: a cross-sectional survey by Jean-Dominique Dewitte, Brice Loddé, Richard Pougnet, David Lucas, Sandrine Brient, Bisi Moriamo Eveillard, Annabelle Gressier, Tanguy LeGrand

“…Being an HCW was a predictive factor for stress (OR 1.47, 95% CI 1.04 to 2.08), poor global health (OR 1.71, 95% CI 1.14 to 2.55) and negative perception of work activity environment (OR 1.9, 95% CI 1.3 to 2.8).Conclusion We have shown that all HCWs suffered from some health impact shortly after the first peak of the COVID-19 outbreak. …”
Get full text

Metastatic melanoma: An integrated analysis to identify critical regulators associated with prognosis, pathogenesis and targeted therapies. by Zeinab Chaharlashkar, Yousof Saeedi Honar, Meghdad Abdollahpour-Alitappeh, Sepideh Parvizpour, Abolfazl Barzegar, Effat Alizadeh

“…The items recognized in the current study can be used as potential biomarkers for diagnostic, predictive, and might helpful to develop targeted combined therapies.…”
Get full text

Is There a Role for Daratumumab Retreatment in Patients with Relapsed/Refractory Multiple Myeloma? by Davor Galusic, Ivan Krecak, Viktor Blaslov, Andela Krstulovic Opara, Toni Valkovic, Sandra Basic Kinda

“…However, further research is needed to identify clinical and biological parameters that may predict favorable responses to daratumumab retreatment.…”
Get full text

Experimental and Computational Study of the Formation of Composite Granular Fuel by L. N. Ovchinnikov, N. L. Ovchinnikov, A. V. Mitrofanov, S. V. Vasilevich, S. V. Shpeynova

“….), but have low or poorly predicted physical and mechanical characteristics (strength, granulometric composition, etc.). …”
Get full text

Subsidence Control Design Method and Application to Backfill-Strip Mining Technology by Xiaojun Zhu, Feng Zha, Guangli Guo, Pengfei Zhang, Hua Cheng, Hui Liu, Xiaoyu Yang

“…Then, the surface movement and deformation are predicted based on the equivalent superposition probability integral method (PIM). …”
Get full text

A novel bladder cancer surveillance schedule using bladder Cx for patients on annual surveillance by Arjun Guduguntla, Thomas Whish‐Wilson, Lauren Chandler, Dennis Gyomber

“…Abstract Objectives Cx bladder monitor (CxM) is a urine test with a proven high sensitivity and negative predictive value in bladder cancer surveillance. The aim of this retrospective study was to report on the outcomes of our newly implemented bladder cancer surveillance program for patients eligible for yearly cystoscopy, as per the European Association of Urology (EAU) guidelines. …”
Get full text

Title not available

“…Using multiple logistic regression and GIS technology to predict landslide hazard in northeast Kansas, USA. …”
Get full text

Customized Toric Intraocular Lens Implantation in Eyes with Cataract and Corneal Astigmatism after Deep Anterior Lamellar Keratoplasty: A Prospective Study by Domenico Schiano Lomoriello, Giacomo Savini, Kristian Naeser, Rossella Maria Colabelli-Gisoldi, Valeria Bono, Augusto Pocobelli

“…Toric IOLs can effectively correct corneal astigmatism in eyes with previous DALK. The predictability of cylinder correction is partially lowered by the variability of the surgically induced changes of TCA. …”
Get full text

Clinical course and remodeling of left ventricle in patients with ST segment elevention acute myocardial infarction after primary coronary artery stenting by V.A. Skybchik, Yu.P. Melen

“…The aim – to establish the predictive effect of primary coronary artery stenting on the clinical course and features of left ventricular remodelling in patients with acute ST elevation MI (STEMI) and diastolic dysfunction (DD) in the hospital period. …”
Get full text

Optimization of Edible Coating Formulation Using Response Surface Methodology for Delaying the Ripening and Preserving Tomato (Solanum lycopersicum) Fruits by Franck Laurins Tchouala Tazo, Gabriel Kanmegne, Alain Ngotio Tchinda, Odelonne Justine Kenfack, Eugéne Tafré Phounzong

“…There was no significant difference between the experimental and predicted data.…”
Get full text

How eHealth use and cancer information-seeking influence older adults’ acceptance of genetic testing: Mediating roles of PIGI and cancer worry by Yinxia Zhu, Qian Erica Xiao, Man Chon Ao, Xinshu Zhao

“…Additionally, among demographic variables, educational level was the strongest predictor of genetic test behavior, while gender significantly predicted WCLB, with older female adults showing higher intentions to change their lifestyle based on genetic test results than males. …”
Get full text

Incidence and prognosis associated with troponin elevation after cardiac surgery: a prospective cohort study by Arthur Clement, Lee S Nguyen, Anousone Daulasim, Magali Souibri

“…We aimed to confirm the accuracy of troponin, analysed as time-dependent variable, to predict mortality independently from other biomarkers; and to assess the incidence and prognosis of a 10 times upper normal value threshold (troponin10N) used in the current fourth definition of myocardial infarction.Methods In a prospective cohort of patients who underwent cardiopulmonary bypass cardiac procedures, we assessed the association between serum levels of troponin, creatinine, bilirubin, serum glutamic-oxaloacetic transaminase (SGOT), serum glutamic pyruvic transaminase (SGPT), C-reactive protein (CRP), lactate and in-hospital mortality. …”
Get full text

Differentiating False Loss of Resistance from True Loss of Resistance While Performing the Epidural Block with the CompuFlo® Epidural Instrument by Pasquale Vaira, Michela Camorcia, Tiziana Palladino, Matteo Velardo, Giorgio Capogna

“…We evaluate the sensitivity, specificity, and positive and negative predictive values of the ability of CompuFlo® recordings to correctly identify the true LOR from the false LOR. …”
Get full text

Brief Psychiatric Screening Questionnaire in Parkinson’s Disease by Will Lee, David R. Williams, Andrew Evans

“…Moderate to strong correlation (r = 0.464 − 0.733, p<0.004) between predicted scores based on BPQ questions and actual scores of three validated questionnaires was demonstrated. …”
Get full text

About oxide dispersion particles chemical compatibility with areas coherent dissipation/sub-grains of bcc-alloys in Fe - (Cr, V, Mo, W) systems by Udovsky A., Fabrichnaya O.

“…Using this model it has been predicted that static displacements of Fe - atoms in alloy matrix increase with increasing the of CS number and result in reducing of the area of coherent dissipation (ACD) size with growth of the dimension factor (DF) in the Fe-(Cr, V, Mo, W) systems in agreement with the X-ray experiments. …”
Get full text