Employing the Oncolytic Vesicular Stomatitis Virus in Cancer Virotherapy: Resistance and Clinical Considerations by Alaa A. Abdelmageed, Stephen Dewhurst, Maureen C. Ferran

“…Personalized treatments tailored to tumor molecular profiles, along with identifying biomarkers predictive of resistance to VSV oncolysis, will enhance patient selection and enable more effective, individualized VSV-based therapies.…”
Get full text

Connectivity and community structure of online and register-based social networks by Márton Menyhért, Eszter Bokányi, Rense Corten, Eelke M. Heemskerk, Yuliia Kazmina, Frank W. Takes

“…First and foremost, we find that node metrics and the connectivity of the two population-scale networks are similar, with more long-distance ties captured by the OSN, and with the OSN ties proving to be predictive of RSN ties. These results hold when correcting for population size and geographical distance, notwithstanding that these two factors appear to be the main drivers of connectivity. …”
Get full text

Host RNA-Binding Proteins as Regulators of HIV-1 Replication by Sebastian Giraldo-Ocampo, Fernando Valiente-Echeverría, Ricardo Soto-Rifo

“…Strikingly, several of the RBPs found through interactome capture are not canonical RBPs, meaning that they do not have conventional RNA-binding domains and are therefore not readily predicted as being RBPs. Further studies on the different cellular targets of HIV-1, such as subtypes of T cells or myeloid cells, or on the context (active replication versus reactivation from latency) are needed to fully elucidate the host RBPome bound to the viral RNA, which will allow researchers and clinicians to discover new therapeutic targets during active replication and provirus reactivation from latency.…”
Get full text

Wearable Quarter-Wave Folded Microstrip Antenna for Passive UHF RFID Applications by Thomas Kaufmann, Damith C. Ranasinghe, Ming Zhou, Christophe Fumeaux

“…Measurements on a prototype demonstrate a reflection coefficient (S11) of −30 dB at resonance and a −10 dB bandwidth from 920 MHz to 926 MHz. Simulation results predict a maximum gain of 2.8 dBi. This is confirmed by tag measurements where a 4-meter read range is achieved using a transmit power of 30 dBm, for the case where the passive wearable tag antenna is mounted on a body in a practical setting. …”
Get full text

Experimental Research of Continuous Concrete Beams with GFRP Reinforcement by Nikola Baša, Mladen Ulićević, Radomir Zejak

“…The test results have also been compared to current code provisions, and they have shown that the American Concrete Institute (ACI) 440.1R-15 well predicted the failure load for continuous beams with GFRP reinforcement. …”
Get full text

Performance Analyses and Improvements for IEEE 802.15.4 CSMA/CA Scheme in Wireless Multihop Sensor Networks Based on HTC Algorithm by Jianping Zhu, Chunfeng Lv, Zhengsu Tao

“…Along with these two strategies, the accurate statistical performance metrics of throughput and delay of unsaturated, unacknowledged IEEE 802.15.4 beacon-enabled networks for 1-hop and 2-hop scenarios are then predicted based on the models which contains n modified semi-Markov chains and one macro-Markov chain, in which nodes are assumed to locate randomly over a circle plane according to Poisson distribution. …”
Get full text

Unlocking biological complexity: the role of machine learning in integrative multi-omics by Ravindra Kumar, Rajrani Ruhel, Andre J. van Wijnen

“…Machine learning and ensemble methods allow researchers to model nonlinear relationships and manage high-dimensional data, improving the precision of predictions. This approach paves the way for personalized medicine by identifying unique molecular signatures for individual patients, which can provide valuable insights into treatment planning and support more effective treatment. …”
Get full text

Teaching a neural network modeling socio-economic development of the region by S. V. Romanchukov, O. G. Berestneva, L. A. Petrova

“…Under these conditions, the expansion of the mathematical apparatus and the more active introduction of information technologies (including in the area of Big Data analysis and the construction of predictive models based on artificial neural networks) can be viable. …”
Get full text

An intelligent spam detection framework using fusion of spammer behavior and linguistic. by Amna Iqbal, Muhammad Younas, Muhammad Kashif Hanif, Muhammad Murad, Rabia Saleem, Muhammad Aater Javed

“…Fusion enables the proposed model to automatically learn the interactions between the features during the training process, allowing it to capture complex relationships and make predictions based on both types of features. SD-FSL-CLSTM framework apparently shows the promising result by obtaining a minimum accuracy 97%.…”
Get full text

miR-21 promotes cervical cancer by regulating NTF3 by Yishan Chen, Caiwu Su, Yuke Cai, Lina Ke, Yaxiong Huang

“…We employed bioinformatics tools, including DIANA, Targetscan, miRDB, and miRDIP, to predict the target genes of miR-21. Immunohistochemistry, RT-qPCR, and Western blotting were performed to quantify the expression levels of miR-21-5p and NTF3 in cervical cancer cells. …”
Get full text

Effective energy consumption parameters in residential buildings using Building Information Modeling by N. Amani, A.A. Reza Soroush

“…Building information modeling can help in predicting the energy efficiency in future based on dynamic patterns obtained by visualization of data. …”
Get full text

Mindfulness and decision-making for teachers—the mediating role of self-esteem and the moderating role of experience by Afaf S. Almohammadi

“…However, mindfulness was not predicted by decision-making through negative self-esteem. …”
Get full text

The Employment of ATR-FTIR Spectroscopy and Chemometrics for Authentication of Bawal (Colossoma macromopum) Fish Oil from Palm Oil by Firhani Anggriani, Abdul Rohman, Ronny Martien

“…Multivariate calibration with PLSR using the first derivative spectrum provided the best model for the relationship between actual and predicted FTIR values. At this conditions, the R2 values for the calibration and validation models obtained were 0.9966 and 0.9969, with RMSEC and RMSEP values of 0.0249 and 0.0248, respectively. …”
Get full text

Mathematical Modelling of Host-Pest Interaction in the Presence of Insecticides and Resistance: A Case of Fall Armyworm by Moreen Brenda Gatwiri, Marilyn Ronoh, Cyrus Gitonga Ngari, Dominic Makaa Kitavi

“…Models with resistance would help predict the dynamics of the FAW population, thus mitigating losses. …”
Get full text

Enhancing insights in sexually transmitted infection mapping: Syphilis in Forsyth County, North Carolina, a case study. by Lani Fox, William C Miller, Dionne Gesink, Irene Doherty, Marc Serre

“…We show combining a moving window and a UMBME analysis with geomasked data effectively predicted the true or latent syphilis rate 5% to 26% more accurate than the traditional, geopolitical boundary method. …”
Get full text

Frequency of mortality in patients with high AIMS65 score presenting with upper GI bleed by Javeria Zahid Khan, Saima Ambreen, Sidra Jahangir, Aimen Malik, Bushra Khaar, Muhammad Umar

“… Introduction: Upper gastrointestinal bleeding is a common reason for hospitalisation across the world, with a UK frequency of 10% and a death rate of 8-14 percent. [1] Several risk assessment scores have been created to predict clinically relevant outcomes like death, the requirement for hospital-based care, rebleeding, and hospital stay length Objective: To determine frequency of mortality in patients with high AIMS65 score presenting with upper gastrointestinal bleeding. …”
Get full text

The Impact of Policy Quantification on Rural Spatial Development in Suburbs: A Case Study of Dalian’s Main Urban Area by Jiaxiang Wang, Zehao Cao, Tian Chen, Chunguang Hu

“…Granger causality analysis confirmed the strong influence of policy interventions, with the first-order lag VAR model offering reliable predictions of short- and long-term policy effects. …”
Get full text

Molecular docking and quantitative structure-activity relationships for a series of Trypanosoma cruzi dihydroorotate dehydrogenase inhibitors by Gabriela Ciffeli de Jesus, Tatiana Santana Ribeiro, Adriano D. Andricopulo, Leonardo Luiz Gomes Ferreira

“…The results indicate a highly predictive 2D Hologram QSAR (HQSAR) model (q 2 = 0.65, r 2 = 0.88, and r 2 pred = 0.82) that identified key molecular fragments that correlate with DHODH inhibition. …”
Get full text

Understandings on the Performance of Concrete-Filled Steel Tube with Different Kinds of Concrete Infill by K. B. Manikandan, C. Umarani

“…The analytical investigations were carried out by using Eurocode-4 to predict the load-bearing capacity of CFST columns under axial compression. …”
Get full text

Sleep Spindles Characteristics in Insomnia Sufferers and Their Relationship with Sleep Misperception by Marie-Pier Normand, Patrick St-Hilaire, Célyne H. Bastien

“…A standard multiple regression model revealed that neither sleep spindles characteristics nor objective sleep measures were predictive of sleep misperception. A longer duration of spindles could reflect a higher gating process but this hypothesis still needs to be confirmed in replication studies.…”
Get full text