GPX3 as a Novel and Potential Therapeutic Target in the Shared Molecular Mechanisms of Traumatic Brain Injury and Parkinson’s Disease by Wang Y, Fang J, Yuan Q, Yu J, Hu J

“…Further analyses, including GO and KEGG pathway enrichment, protein-protein interaction (PPI) network construction, hub gene identification, as well as miRNA and transcription factor prediction and drug candidate screening, were conducted. …”
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Protective effects of seed oil from Nicotiana tabacum L. On D-galactose induced liver and brain damages of mice by regulating PI3K/Akt/Nrf2 signaling pathway by Ji Gu, Yongchao Wang, Shanshan Xiao, Yunye Zheng, Zhengxuan Wang, Yaping Liu, Limeng Zhang, Guiguang Cheng

“…Combined with GC/MS component analysis and network pharmacology prediction, the aging related PI3K/Akt/Nrf2 pathway was found for further verification. …”
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Chromosome-level genome assembly and annotation of largemouth bronze gudgeon (Coreius guichenoti) by Xuemei Li, Xingbing Wu, Yongjiu Zhu, Xiaoli Li, Zihao Meng, Nian Wei, Miao Xiang, Deguo Yang, Tingbing Zhu

“…Moreover, a total of 22,506 protein-coding genes were predicted with average intron length of 2293 bp. Evolutionary analysis and divergence time prediction revealed that C. guichenoti was closely related to C. heterodon and they phylogenetically diverged from common ancestor ~20.7 million years ago (Mya), following the separation of Cyprinidae at 28.3 Mya. …”
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A novel regional forecastable multiscalar standardized drought index (RFMSDI) for regional drought monitoring and assessment by Aamina Batool, Veysi Kartal, Zulfiqar Ali, Miklas Scholz, Farman Ali

“…FCA reduce dimension by focus on components that are inherently more predictable. It ensures that reduced data has a built-in ability to predict future trends by selecting the maximized forecastable components. …”
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Taming of trinitromethyl-oxadiazole to access high density and high oxygen balance via a dual modulation strategy by Jinya Zhang, Teng Fei, Jingwei Meng, Jinxiong Cai, Lei Zhang, Siping Pang, Chunlin He

“…Notably, practical crystal morphology prediction was creatively introduced to guide the experimental crystallization conditions of 3, increasing the impact sensitivity and friction sensitivity from 1 J to 80 N (3-a) to 10 J and 240 N (3-b), respectively. …”
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Integrative analysis of ferroptosis in the hypoxic microenvironment of gastric cancer unveils the immune landscape and personalized therapeutic strategies by Xiao Xu, Liangling Fa, Xiaoxiao Sun, Fangfang Yang, Yongrui Liu, Jifu Song, Yongli Zhao, Jigang Dong, Jigang Dong

“…The FHRS can independently predict prognosis in gastric cancer. Assessing the molecular status of ferroptosis-hypoxia in individual patients will help in selecting more suitable immunotherapy regimens by providing a better understanding of TME characteristics and predicting immunotherapeutic outcomes.…”
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Clinical validation of a biopsy‐based six‐gene signature prognostic for aggressive prostate cancer by Agnieszka Krzyzanowska, Debra F. Higgins, Stephen Barron, Tony Loughman, Amanda O'Neill, Katherine M. Sheehan, Chan‐Ju Angel Wang, Bozena Fender, Leah McGuire, Joanna Fay, Anthony O'Grady, Des O'Leary, R. William Watson, Anders Bjartell, William M. Gallagher

“…Abstract Objectives This study aimed to clinically validate the six‐gene prognostic molecular clinical risk score (MCRS) for the prediction of aggressive prostate cancer in diagnostic biopsy tissue. …”
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Risk Factors for Postoperative Nausea and Vomiting After TACE: A Prospective Cohort Study by Yuzhu Wang, Xin Zhou, Guoping Li, Qianzhou Lv, Xiaoyu Li, Zhiping Yan

“…Chronic gastritis, pain, epirubicin, and the dosage of lipiodol were independent risk factors for PONV. The risk prediction model that was constructed according to the aforementioned factors demonstrated good discriminatory capacity for predicting the risk of post-TACE PONV, which can improve the recognition of medical providers, and has a good ability to prevent and treat nausea and vomiting.…”
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Scrutinizing the evidence of anthracene toxicity on adrenergic receptor beta-2 and its bioremediation by fungal manganese peroxidase via in silico approaches by Muhammad Naveed, Khadija Khatoon, Tariq Aziz, Rida Naveed, Muhammad Nouman Majeed, Maida Salah Ud Din, Tayyab Javed, Ayaz Ali Khan, Abdullah F. Alasmari

“…This study aims to alleviate the adverse environmental effects of anthracene through fungal degradation, focusing on bioremediation approaches using bioinformatics. Toxicity prediction using Pro-Tox 3.0 identified anthracene as a compound of toxicity class 4 with a LD50 of 316 mg/kg. …”
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Constraints of S–Pb–Sr Isotope Compositions and Rb–Sr Isotopic Age on the Origin of the Laoyingqing Noncarbonate-Hosted Pb–Zn Deposit in the Kunyang Group, SW China by Hongsheng Gong, Runsheng Han, Peng Wu, Gang Chen, Lingjie Li

“…This study is aimed at investigating whether the Laoyingqing deposit has the same ore-forming age and type as other Pb–Zn deposits related to the Pb–Zn metallogenic system and prospecting prediction of the deep and peripheral areas of the deposits in the SYGT. …”
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The Bony Density of the Pedicle Plays a More Significant Role in the Screw Anchorage Ability Than Other Regions of the Screw Trajectory by Zan Chen, Yue Chen, Jiajun Zhou, Yanwei He, Jingchi Li

“…Specifically, the AUC of screw loosening prediction was notably higher when using HU values of the pedicle compared to other methods (AUC in the pedicle > 0.9 and in the screw insertion position > 0.7). …”
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Weakly supervised deep learning-based classification for histopathology of gliomas: a single center experience by Mingrong Zuo, Xiang Xing, Linmao Zheng, Hao Wang, Yunbo Yuan, Siliang Chen, Tianping Yu, ShuXin Zhang, Yuan Yang, Qing Mao, Yongbin Yu, Ni Chen, Yanhui Liu

“…Heatmap visualizations showed the prediction mechanism of the model. The results were promising, with high AUC values for differentiating grades of astrocytomas, oligodendrogliomas, all gliomas, and glioma types in the TCGA dataset (0.9419, 0.8659, 0.9904, and 0.9298, respectively), and in the WCH cohort (0.9048, 0.7423, 0.9510, and 0.7098, respectively). …”
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The relationship between anthropometric indices and non-alcoholic fatty liver disease in adults: a cross-sectional study by Mina Radmehr, Reza Homayounfar, Reza Homayounfar, Abolghasem Djazayery

“…ABSI demonstrated poor predictive power (men: AUC = 0.530, women: AUC = 0.505) and is not recommended for NAFLD prediction.ConclusionBased on the findings, BMI and WHtR emerge as the most practical and accessible indicators for early screening of NAFLD in both men and women, while ABSI shows minor effectiveness in identifying the disease.…”
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Blepharoplasty: historical aspects, terminology, and modern ideas by A.D. Kazantsev, E.P. Kazantseva, I.B. Alekseev

“…Modern, highly effective diagnostic tools and professional medical equipment allow for an accurate prediction of surgical outcome, thereby emphasizing the importance of the conception "desired changes — realistic expectations". …”
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The prognostic value of the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in colorectal cancer and colorectal anastomotic leakage patients: a retrospe... by Nuo Xu, Jian-Xin Zhang, Jia-Jie Zhang, Zhuo Huang, Lian-Chun Mao, Zhi-Yong Zhang, Wei-Dong Jin

“…Nomogram and calibration curve analysis will further improve the accuracy of OS and DFS prediction.…”
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Clinical significance of hyperuricaemia in biopsy-proven diabetic kidney disease ━ a single-centre retrospective study by Jin Yu, Jin Yu, Xiao Tu, Xiao Tu, Kunyue Xu, Xuanli Tang, Xuanli Tang, Yufan Wu, Xue Jiang, Xue Jiang

“…In the testing and training sets, the AUCs at 1, 3, and 5 years were 0.888, 0.939, and 0.886 and 0.947, 0.867, and 0.905, respectively.ConclusionThe clinicopathologic manifestation of DKD patients with hyperuricaemia was much more severe, and hyperuricaemia predicted a worse renal prognosis. A new renal prognosis prediction model including SUA was constructed for DKD with higher accuracy.…”
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The incidence of and risk factors for axillary web syndrome with limited shoulder movement after surgery for breast cancer, and the effect of early physical therapy intervention by Ya-Hui Chou, Su-Fen Liao, Dar-Ren Chen, Shou-Tung Chen, Wei-Te Wang

“…Conclusions In conclusion, we demonstrated a prediction model for AWS with shoulder movement limitation using 3 risk factors: younger age, a higher number of removed lymph nodes, and receiving NAC. …”
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Role of B7H4 and Fas in regulation of trophoblast cells and development of pre-eclampsia: a cross-sectional study by Xiujuan Dong, Cuicui Nie, Yanli Yin, Haixia Xu, Yanxia Zhang, Lihua Han, Congcong Xu

“…The upstream regulators of B7H4 in trophoblasts were predicted and estimated using a luciferase reporter assay. …”
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Attention-Driven Hybrid Ensemble Approach With Bayesian Optimization for Accurate Energy Forecasting in Jeju Island’s Renewable Energy System by Muhammad Ali Iqbal, Joon-Min Gil, Soo Kyun Kim

“…For daily supply predictions, it demonstrated a 76% reduction in MAE and a 77% reduction in RMSE, while for daily demand predictions, the reductions were 70% in MAE and 69% in RMSE. …”
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Association of preoperative ultrasonographic parameters of the contralateral kidney with long-term serum creatinine in cats treated for unilateral ureteral obstruction by Diego Pulido Vega, Jérémie Ficheroulle, Jérémie Ficheroulle, Mathieu Manassero, Jeremy Mortier, Christelle Maurey

“…IntroductionPrediction of renal recovery after surgical management of feline unilateral ureteral obstruction (UO) is crucial to guide therapeutic decisions, but predictors of this outcome are still lacking. …”
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