-
9881
The gastric microbiome altered by A4GNT deficiency in mice
Published 2025-02-01“…The co-occurrence network appeared to be much more complex. Functional prediction demonstrated considerable decreases in the relative frequencies of functions associated with polysaccharide metabolism and transportation.ConclusionThe distinct profile in A4gnt−/− mice demonstrated a vital role of A4GNT in the establishment of the gastric microbiome. …”
Get full text
Article -
9882
Proteomic Profiling Towards a Better Understanding of Genetic Based Muscular Diseases: The Current Picture and a Look to the Future
Published 2025-01-01“…Proteomics accelerates diagnosis and research of muscular diseases by enabling the robust analysis of proteins relevant for the manifestation of neuromuscular diseases in the following aspects: (i) evaluation of the effect of genetic variants on the corresponding protein, (ii) prediction of the underlying genetic defect based on the proteomic signature of muscle biopsies, (iii) analysis of pathophysiologies underlying different entities of muscular diseases, key for the definition of new intervention concepts, and (iv) patient stratification according to biochemical fingerprints as well as (v) monitoring the success of therapeutic interventions. …”
Get full text
Article -
9883
Modeling the endocrine control of vitellogenin production in female rainbow trout
Published 2013-12-01“…We anticipate that these mathematical and computational models will play an important role in future regulatory toxicity assessments and in the prediction of ecological risk.…”
Get full text
Article -
9884
An Inflammatory Polymorphisms Risk Scoring System for the Differentiation of Ischemic Stroke Subtypes
Published 2015-01-01“…The genetic risk scoring system could be useful in the prediction and differentiation of ischemic stroke; however, it might be specific to particular ischemic stroke subtypes.…”
Get full text
Article -
9885
Integration of bulk and single-cell RNA-seq reveals prognostic gene signatures in patients with bladder cancer treated with immune checkpoint inhibitors
Published 2024-12-01“…This study aims to identify reliable biomarkers to enhance the prediction of treatment outcomes. Bulk RNA expression data from a BC cohort (GSE176307) receiving ICI and single-cell sequencing data from patients with BC (GSE135337) were collected. …”
Get full text
Article -
9886
Optimization of Extraction of Compound Flavonoids from Chinese Herbal Medicines Based on Quantification Theory and Evaluation of Their Antioxidant Activity
Published 2022-01-01“…The result was accurate and the established prediction equation was reliable (R = 0.95). The antioxidant activity of CFs was significantly positively correlated with the concentration from 0.05 to 0.4 mg/mL. …”
Get full text
Article -
9887
Interpretable machine learning modeling of temperature rise in a medium voltage switchgear using multiphysics CFD analysis
Published 2025-01-01“…SHAP analysis identified the most significant variables affecting temperature prediction as current, air velocity, duct area, and switchgear conditions, in that order.…”
Get full text
Article -
9888
Prevalence, Awareness, Treatment, and Control of Hypertension among Chinese First-Generation Migrants and Italians in Prato, Italy: The CHIP Study
Published 2017-01-01“…In Chinese participants, where the optimum cut-off point for body mass index was ≥23.9 kg/m2, the sensibility and specificity prediction for hypertension were 61.7% and 59.8%, respectively (area under the ROC curve = 0.629). …”
Get full text
Article -
9889
Cognitive and Emotional Resilience in Parents with Children with Autism Spectrum Disorder During COVID-19: The Role of Promoting Variables
Published 2025-01-01“…We hypothesised that higher scores in these promoting variables would predict greater resilience, with emotional intelligence potentially serving as an underlying framework. …”
Get full text
Article -
9890
Sodium butyrate regulates macrophage polarization by TGR5/β-arrestin2 in vitro
Published 2025-01-01“…Methods The targets of butyric acid were identified using SwissTargetPrediction database and surface plasmon resonance (SPR). …”
Get full text
Article -
9891
The Relationship Between First-Trimester Aneuploidy Markers and Birth Weight
Published 2021-12-01“… OBJECTIVE: We aimed to determine the relationship between the first-trimester aneuploidy screeningma and the predicted weight at birth: Small for gestational age and large for gestational age. …”
Get full text
Article -
9892
High-throughput screening of CO2 cycloaddition MOF catalyst with an explainable machine learning model
Published 2025-01-01“…Among them, MOF-76(Y) achieved the top performance experimentally among reported MOFs, in good agreement with the prediction.…”
Get full text
Article -
9893
Deciphering olfactory receptor binding mechanisms: a structural and dynamic perspective on olfactory receptors
Published 2025-01-01“…Furthermore, due to the rapid advancements in related fields such as computer simulations, the prediction and exploration of odor molecule binding to olfactory receptors have been progressively achieved through molecular dynamics simulations. …”
Get full text
Article -
9894
Numerical and Experimental Investigation of the Effect of Cavitation on Dual Clearance Squeeze Film Damper
Published 2021-01-01“…The film pressure distribution in the outer layer (including the positive and negative pressure zones) obtained from the experimental test agrees well with the numerical prediction, which verifies the validity of the proposed numerical model. …”
Get full text
Article -
9895
Above dendromass estimation of juvenile Paulownia sp.
Published 2016-10-01“…The regression models were fitted in log-transformed form to the logarithm of the stem biomass and MM correction factor for bias was applied to the back-transformed prediction data. Two allometric relationships were derived, which adequately assess stem dendromass of young Paulownia sp. from easily measurable tree characteristics. …”
Get full text
Article -
9896
A topology-guided high-quality solution learning framework for security-constraint unit commitment based on graph convolutional network
Published 2025-03-01“…Thirdly, a customized prediction-based NS is developed to restore the feasibility of the predicted commitment. …”
Get full text
Article -
9897
Effect of electrical stimulation with a cochlear implant on tinnitus impact: protocol of an individual patient data meta-analysis
Published 2022-06-01“…We will also apply prediction models to individual patient data (IPD) of clinical trials to find predictive factors of the effect of electrical stimulation on tinnitus impact.Method and analysis The IPD meta-analysis is a follow-up project of the systematic review on cochlear implantation in patients with tinnitus as a primary complaint. …”
Get full text
Article -
9898
Optimization of Reservoir Water Quality Parameters Retrieval and Treatment Using Remote Sensing and Artificial Neural Networks
Published 2024-06-01“…Using MLP-ANN modelling, the extracted spectral reflectance values from the selected sampling points in the reservoir were used as model inputs for the prediction of treated WQPs. A second MLP-ANN model was developed to predict the optimum coagulant dose required for raw water treatment. …”
Get full text
Article -
9899
Optimizing Stroke Detection Using Evidential Networks and Uncertainty-Based Refinement
Published 2025-01-01“…Using deep learning methods, particularly an evidential network, we distinguished impaired participants from healthy controls while generating measures of prediction uncertainty. By retraining the network with the least uncertain samples and refining the test set by excluding the top 10% most uncertain samples, we improved the sensitivity of detecting subtle impairments in minimally impaired stroke patients (those scoring normal on the CMSA) from 0.55 to 0.75. …”
Get full text
Article -
9900
Quantitative Structure–Activity Relationship (QSAR) Modeling of Chiral CCR2 Antagonists with a Multidimensional Space of Novel Chirality Descriptors
Published 2025-01-01“…The linear regression using the principal component scores (PCSs) resulted in a three-predictor prediction model with good statistics: R<sup>2</sup> = 0.823; Adj R<sup>2</sup> = 0.790. …”
Get full text
Article