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7601
Deciphering the role of flutamide, fluorouracil, and furomollugin based ionic liquids in potent anticancer agents: Quantum chemical, medicinal, molecular docking and MD simulation...
Published 2025-01-01“…Such as, toxicity evaluation based on the TOX21 pathway confirmed the non-toxic attributes of these ILs, bolstering their potential as antitumor drugs. The metabolic prediction for [FM1]+ was consistent with its expected behavior in the biological system with its likelihood ranging from 89 % to 83 %. …”
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7602
Film Recommender System Menggunakan Metode Neural Collaborative Filtering
Published 2023-07-01“…The recommendation system will help users find items based on their respective interests by providing predictions. The recommender system will help a user find an item based on their respective interests by providing predictions of several items based on user preferences derived from the user's assessment history of the item. …”
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7603
Pengembangan Auto-AI Model Generatif Analisis Kompleksitas Waktu Algoritma Untuk Data Multi-Sensor IoT Pada Node-RED Menggunakan Extreme Learning Machine
Published 2022-12-01“…Based on the tests that have been carried out, the difference in value between the actual data and the prediction results in the size of the MAPE average value of 11.90%, which shows a fairly small error value. …”
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7604
A new prognostic model based on serum apolipoprotein AI in patients with HBV-ACLF and acutely decompensated liver cirrhosis
Published 2025-02-01“…Conclusion In HBV-ACLF and AD patients, lower serum apoAI levels suggest greater disease severity and 90-day mortality risk. For predicting the short-term prognosis of these patients, the new Lip-ACLF score might serve as a potential model.…”
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7605
Targeting aldose reductase using natural African compounds as promising agents for managing diabetic complications
Published 2025-02-01“…The ADMET and protein-ligand interaction results revealed that these compounds interacted with key inhibiting residues through hydrogen and hydrophobic interactions and demonstrated favorable pharmacological and low toxicity profiles. Prediction of biological activity highlighted Zinc000095485961 and 1,6-di-o-p-hydroxybenzoyl-beta-d-glucopyranoside as having significant inhibitory activity against aldose reductase. …”
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7606
Proteomics unveil candidate biomarkers and pathogenesis of subacute thyroiditis
Published 2025-02-01“…Thus, these high-abundance proteins can potentially serve as biomarkers for SAT diagnosis and outcome prediction. Our findings provide valuable insights into SAT biomarkers and shed light on the potential pathogenesis and therapeutic targets of SAT.…”
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7607
Assessment of the influence of gap wall mobility factor at calculation of leakage in working section of a scroll compressor. Part 1
Published 2023-03-01“…In this case relevance consists in increase of accuracy of compressor losses calculation and prediction of refrigeration machine characteristics. …”
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7608
Identification of patient demographic, clinical, and SARS-CoV-2 genomic factors associated with severe COVID-19 using supervised machine learning: a retrospective multicenter study
Published 2025-01-01“…Conclusions Viral genomic features have limited utility in predicting hospitalization across SARS-CoV-2 diversity. …”
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7609
Identification of Staphylococcus aureus, Enterococcus faecium, Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii from Raman spectra by Artificial Intelligen...
Published 2025-02-01“…This finding confirms the clinical utility of the system while laying a solid foundation for the future development of antimicrobial resistance prediction models.…”
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7610
Serum advanced glycation end products as a putative biomarker in Type2 DKD patients’ prognosis
Published 2025-01-01“…This study introduced corrected lgAGEs [novel biomarker derived by adjusting logarithmically transformed AGEs (lgAGEs) levels based on serum albumin (ALB) levels] to enhance the prediction of adverse renal outcomes in patients with type 2 DKD (T2DKD).MethodsIn this prospective cohort study, 196 T2DKD patients were followed up longitudinally. …”
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7611
Application of copy number variation sequencing combined with whole exome sequencing in prenatal left–right asymmetry disorders
Published 2025-01-01“…Further bioinformatics scrutiny was conducted to assess the protein structure and function prediction of these variants, ultimately indicating their potential pathogenicity. …”
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7612
Efficacy and safety of PD-1/PD-L1 inhibitors in advanced or recurrent endometrial cancer: a meta-analysis with trial sequential analysis of randomized controlled trials
Published 2025-01-01“…To evaluate heterogeneity, we employed Cochran’s Q test, I2 statistics, and 95% prediction intervals (PIs). Trial sequential analysis (TSA) was conducted using R Version 4.3.1, STATA Version 12.0, and TSA Version 0.9.5.10 Beta software.ResultsOur analysis incorporated 6 studies, encompassing a total of 2,954 patients. …”
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7613
Machine learning helps reveal key factors affecting tire wear particulate matter emissions
Published 2025-01-01“…The random forest (RF) model was developed and displayed good prediction performance with an R2 of 0.84 and 0.78 for PM2.5 and PM2.5-10 on the test set, respectively. …”
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7614
BIJAKAWEB: Platform Berbasis Web Untuk Deteksi Hate Speech Pada Komentar Berita Bahasa Indonesia
Published 2024-08-01“…This research has produced several significant contributions, including the availability of a new dataset for relevant research, a fine-tuned IndoBERT model accessible to the public on HuggingFace, and the development of the BijakaWeb platform using the full-stack Django framework, capable of real-time scraping and hate speech prediction. It is hoped that this research can assist news portals in moderating online news comments to combat hate speech and provide a model that can be used and adapted by other online news platforms to prevent the spread of hate speech on the internet. …”
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7615
Predictors of Noncompliance to Antihypertensive Therapy among Hypertensive Patients Ghana: Application of Health Belief Model
Published 2018-01-01“…Overall, the five HBM constructs explained 31.7% of the variance in noncompliance to AHT with a prediction accuracy of 77.5%, after adjusting for age, gender, and duration of condition. …”
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7616
Evaluation of the Prognostic Value of Red Cell Distribution Width to Total Serum Calcium Ratio in Patients with Acute Pancreatitis
Published 2021-01-01“…The objective of the study was to evaluate whether RDW/TSC can be used to predict the prognosis of patients with AP at an early stage. …”
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7617
Differentiation between glioblastoma and solitary brain metastases using perfusion and amide proton transfer weighted MRI
Published 2025-02-01“…Combinations of nAPTwmax + ncCBVmax, nAPTwmean + ncCBVmean, nAPTwmax + nCBFmax, nAPTwmax + K2max and nAPTwmax + ncCBVmax + K2max in ET showed significant prediction in differentiating GBM and MET (AUC = 0.92, 0.82, 0.92, 0.85, and 0.92 respectively).ConclusionWhen assessed in Gd-enhanced tumor areas, nAPTw MRI signal intensity alone or combined with DSC-MRI parameters, was an excellent predictor for differentiating GBM and MET. …”
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7618
Integrating pharmacogenomics and cheminformatics with diverse disease phenotypes for cell type-guided drug discovery
Published 2025-01-01“…We validate the drugs predicted in our proofs-of-concept using real-time polymerase chain reaction (qPCR) experiments. …”
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7619
Knowledge Distillation in Object Detection for Resource-Constrained Edge Computing
Published 2025-01-01“…YOLOv4 is a widely used OD model with a backbone for image feature extraction and a prediction layer. Originally, YOLOv4 was designed to use CSPDarkNet53 as its backbone, which requires significant computational power. …”
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7620
Low-grade systemic inflammation, but not neuroinflammation, is associated with 12-month postoperative outcome after total hip arthroplasty in patients with painful osteoarthritis:...
Published 2024-12-01“…Aims: Better prediction of outcome after total hip arthroplasty (THA) is warranted. …”
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