Multiplex immunohistochemistry to explore the tumor immune microenvironment in HCC patients with different GPC3 expression by Mingzhen Zhou, Ziyan Zhou, Lina Hu, Sidong Chen, Fanyan Meng, Jun Chen, Jie Shen

“…Different levels of GPC3 expression levels can predict the effectiveness of targeted combination immunotherapy in HCC patients. …”
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Human hair biochar to remove malachite green dye and bisphenol-A contamination by M. Kamaraj, P. Kamali, R. Kaviya, K. Abishek, B. Navinkumar, T.G. Nithya, L.S. Wong, J. Aravind

“…Through analysis of variance and numerical expectation, the optimal potential of hydrogen, duration, and Human hair biochar dose was predicted as 3, 150 minutes, and 0.5 grams per liter, which resulted in a maximum removal of 96 percent for malachite green and 83 percent for bisphenol-A.CONCLUSION: This study demonstrated the facile heat-assisted development of biochar from human hair waste as a potential candidate for environmental remediation. …”
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Tax Exemptions and R;D Expenditures in Iran Saeed Dorokhshi Moghaddam by Saeed Dorokhshi Moghaddam, Bahram Sahabi, Hassan Heydari, Sajad Barkhordari

“…In particular, the usual use of linear models is not a very accurate and correct method because it does not guarantee that the values predicted by these estimates are in the range of 0 and 1. …”
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Research Reports on Assessment of Handwriting Ability in Children Aged 6-12 Years by Using Smart Handwriting Analysis Recognition Platform by HAN Ping, YANG Wenyi, XIE Yiyang, XIE Qiurong, WANG Jiawei, YANG Caihong, ZHAN Shiqi, YAN Zhaoshan, ZHANG Yu

“…Writing outcome accuracy explained only 39.1% of the variation in overall writing performance, and writing outcome accuracy, time-on-paper ratio, writing control, and writing integration together explained 71.8% of the variation in overall writing performance.ConclusionAt the primary level, girls generally outperform boys in writing ability, but sex and dominant hand still do not predict overall performance in writing. As the grades increase, students' writing abilities tend to mature. …”
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Unveiling neurogenic biomarkers for the differentiation between sepsis patients with or without encephalopathy: an updated meta-analysis by Jiyun Hu, Wenchao Li, Shucai Xie, Ya Liao, Tao Chen, Xinrun Wang, Weiping Xia, Fang Huang, Zhaoxin Qian, Lina Zhang

“…Conclusion The increased serum neurogenic biomarkers may be predictive of SAE and mortality for septic patients, which are expected to be applied as a reliable blood-based diagnostic tool for detection and longitudinal monitoring in SAE patients. …”
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BRAF inhibitor monotherapy in BRAFV600E-mutated pediatric low-grade glioma: a single center’s experience by S. S. McThenia, S. S. McThenia, S. S. McThenia, K. M. Reddy, K. M. Reddy, E. Damaraju, E. Castellino, Z. He, R. Beer, F. Chien, F. Chien, F. Chien, R. C. Castellino, R. C. Castellino, R. C. Castellino, A. E. Goldman-Yassen, A. E. Goldman-Yassen, J. R. Fangusaro, J. R. Fangusaro, J. R. Fangusaro, T. MacDonald, T. MacDonald, T. MacDonald

“…MRI brain imaging data at baseline and best response was evaluated to identify patterns that may predict response to BRAF inhibition monotherapy.ResultsFifteen patients diagnosed with BRAFV600E mutated pLGG, treated with monotherapy BRAF inhibition, were identified. …”
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Functionally important respiratory symptoms and continued cigarette use versus e-cigarette switching: population assessment of tobacco and health study waves 2-6Research in context by James D. Sargent, Kristin Lauten, Kathryn C. Edwards, Susanne E. Tanski, Todd A. MacKenzie, Laura M. Paulin, Mary F. Brunette, Maciej L. Goniewicz, Amanda Malasky, Debra Stark, Fernando B. de Moura, Holly Griffin, Kimberly H. Nguyen, Eric Backlund, Heather L. Kimmel, John H. Kingsbury, Jenny E. Ozga, K Michael Cummings, Andrew Hyland

“…Multivariable models assessed how changes in cigarette use predicted worsening/improvement of symptoms. Findings: Among those with an index score <2, 3.5% switched to e-cigarettes, and 11.1% quit all tobacco. …”
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Type III procollagen peptide level can indicate liver dysfunction associated with volume overload in acute heart failure by Akihiro Shirakabe, Hirotake Okazaki, Masato Matsushita, Yusaku Shibata, Shota Shigihara, Suguru Nishigoori, Tomofumi Sawatani, Nozomi Sasamoto, Kazutaka Kiuchi, Masanori Atsukawa, Norio Itokawa, Taeang Arai, Nobuaki Kobayashi, Kuniya Asai

“…A high P3P level at admission may be able to predict adverse outcomes in AHF patients.…”
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Interaction of human gut microbiota and local immune system in progression of colorectal adenoma (MIMICA-1): a protocol for a prospective, observational cohort study by Jurate Valciukiene, Egle Lastauskiene, Aida Laurinaviciene, Aida Laurinaviciene, Matas Jakubauskas, Marius Kryzauskas, Ruta Barbora Valkiuniene, Ruta Barbora Valkiuniene, Renaldas Augulis, Renaldas Augulis, Ausra Garnelyte, Justinas Kavoliunas, Ugne Silinskaite, Tomas Poskus

“…The newly colon-site adapted AI-based analysis of immune infiltrates is able to predict long-term outcomes of colon carcinoma. Though it could also facilitate the pathologic evaluation of precancerous lesion’s potential to progress. …”
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Standardised packaging, minimum excise tax, and RYO focussed tax rise implications for UK tobacco pricing. by Rosemary Hiscock, Nicole H Augustin, J Robert Branston, Anna B Gilmore

“…<h4>Conclusions</h4>There was no long-term lowering of tobacco prices after the implementation of standardised packaging as predicted by the industry. The introduction of the MET was successful in increasing the price of the cheapest FM cigarettes and narrowing the price gap between FM brands. …”
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Comparing spirometry, impulse oscillometry with computed tomography for assessing small airway dysfunction in subjects with and without chronic obstructive pulmonary disease by Suyin Huang, Fan Wu, Zhishan Deng, Jieqi Peng, Cuiqiong Dai, Lifei Lu, Kunning Zhou, Xiaohui Wu, Qi Wan, Gaoying Tang, Shengtang Chen, Changli Yang, Yongqing Huang, Shuqing Yu, Pixin Ran, Yumin Zhou

“…Spirometry-defined SAD was defined as at least two of maximal mid-expiratory flow (MMEF), forced expiratory flow 50% (FEF50), and forced expiratory flow 75% (FEF75) less than 65% of predicted. IOS-defined SAD was defined as peripheral airway resistance R5 − R20 > 0.07 kPa/L/s. …”
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Effect of modified Morita therapy combined with motor imagery training on pulmonary rehabilitation of elderly patients with chronic obstructive pulmonary disease (改良森田疗法结合运动想象在老年慢性... by ZHOU Chunxiang (周春香), SUN Renjuan (孙仁娟), ZHOU Ru (周茹), TANG Jinghua (唐静华), DING Yexia (丁叶霞), ZHANG Xiaofeng (张晓枫), ZHANG Jianxia (张剑霞)

“…Results After intervention, the value of forced expiratory volume in 1 s (FEV1), forced expiratory volume in one second/predicted value ratio(FEV1%pred), forced vital capacity (FVC), FEV1/FVC of the observation group were higher than those of the control group (P＜0. 05). …”
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Intervention effect and mechanism of Dracocephalum moldavica L. extract on bleomycin-induced pulmonary fibrosis in rats by Xiaoyu SUN, Li CHEN, Ruifang GAO, Hui YU, Min JIN

“…A protein-protein interaction (PPI) was constructed using the Search Tool for the Retrieval of Interacting Genes (STRING) database and Cytoscape software. The predicted potential targets were analyzed by the Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses through the Database for Annotation, Visualization and Integrated Discovery (DAVID) and validated by molecular docking. …”
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Biosynthesis inhibition of miR-142-5p in a N 6-methyladenosine-dependent manner induces neuropathic pain through CDK5/TRPV1 signaling by Jinshi Li, Yang Guo, Chen Zhu, Dongxu Wang, Yuan Li, Xiaotong Hao, Linyan Cao, Yiting Fan, Bo Fang

“…According to database predictions, miR-142-5p, identified as a shared upstream molecule of TRPV1 and CDK5, exhibited downregulation following induction by NP. …”
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Association of the blood urea nitrogen to serum albumin ratio and all-cause mortality in critical ill acute ischemic stroke patients: a retrospective cohort study of MIMIC-IV datab... by Yongwei Huang, Zongping Li, Jianjun Wang, Jianjun Wang, Decai Wang, Decai Wang, Xiaoshuang Yin

“…In the subgroup analysis of 365-day ACM, subgroups of HTN, CRRT, and malignancy tumor had an interaction effect (all Pfor interaction &lt; 0.05).ConclusionIn this retrospective cohort study, our findings reveal that a confluence of deteriorated nutritional and renal function is significantly linked to heightened risks of ACM, and BAR may operate as an effective predictive indicator for AIS patients in ICUs. These findings have substantial importance for public health policy and practice. …”
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Modern theoretical-methodological and economic-legal problems of implementing the concept of sustainable development of tourism and recreation in Ukraine by Ion Dubovich, Alla Anishchenko, Nadia Yurkiv, Yuliia Volkovska, Rostyslav Matsko, Oleh Rozhkovych, Mariana-Nadiia Dubovich, Oksana Pylypiak

“…According to the UN World Tourism Organization, this industry accounts for 10% of global GDP and provides approximately 11% of jobs. Scientists predict a steady increase in the importance of tourism and recreation for the global economy in the coming years. …”
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COVID-19 – if the cure is worse than the disease. The Italian chaos by Giuseppe FERRARI

“…Incubation period is uncertain, it is not possible to predict the time needed to a patient to recover completely and test negative to the virus and the possibility to get re-infected is real. …”

Screening of Genes Related to Resistance to Bacterial Leaf Blight in Oryza officinalis by using RNA-seq Technology by Yayun YANG, Feifei ZHANG, Famei ZHANG, Xinxiang A, Chao DONG, Cuifeng TANG, Chunyun YANG, Luyuan DAI

“…And genes related to resistance to bacterial leaf blight in O. officinalis wild rice were predicted.【Results】The 38 O. officinalis wild rice materials from 6 populations showed different disease resistance to 2 strains (CX28-3 and PXO99), and the overall resistance rate was medium or above, among which the highest resistance rate was 93.50% in Ⅴ population and the lowest rate was 62.50% in Ⅲ population. …”
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The prognosis and metabolite changes of NSCLC patients receiving first‐line immunotherapy combined chemotherapy in different M1c categories according to 9th edition of TNM classifi... by Liang Zheng, Fang Hu, Wei Nie, Jun Lu, Bo Zhang, Jianlin Xu, Shuyuan Wang, Ying Li, Xiaoxuan Zheng, Wei Zhang, Yinchen Shen, Runbo Zhong, Tianqing Chu, Baohui Han, Hua Zhong, Xueyan Zhang

“…Nevertheless, a dearth of evidence exists regarding potential survival disparities between NSCLC patients with M1c1 and M1c2 undergoing first‐line immune‐chemotherapy, and reliable biomarkers for predicting treatment outcomes are elusive. Serum metabolic profiles may elucidate distinct prognostic mechanisms, necessitating the identification of divergent metabolites in M1c1 and M1c2 undergoing combination therapy. …”
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Research Status and Prospects of Key Technologies for Rice Smart Unmanned Farms by YU Fenghua, XU Tongyu, GUO Zhonghui, BAI Juchi, XIANG Shuang, GUO Sien, JIN Zhongyu, LI Shilong, WANG Shikuan, LIU Meihan, HUI Yinxuan

“…Rice yield estimation technology is mainly used to predict yield by combining multi-source data and algorithms, but there are still problems such as the difficulty of integrating multi-source data, which requires further research. …”
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