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22901
Integrating rapamycin with novel PI3K/Akt/mTOR inhibitor microRNAs on NOTCH1-driven T-cell acute lymphoblastic leukemia (T-ALL)
Published 2024-07-01“…Results: Six miRNAs (miR-3143, miR-3182, miR-99a/100, miR-155, miR-576-5p, and miR-501- 3p) were predicted as inhibitors of PI3K/AKT/mTOR pathway. The expression analysis of both clinical samples and the Jurkat cell line revealed a simultaneous downregulation of miR-3143 and miR-3182. …”
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22902
Perbedaan Rasio Kolesterol Total/ HDL Kelompok Kontrol dan Kelompok Diet Tinggi Minyak Sawit pada Tikus Wistar
Published 2014-09-01“…<br />Kata kunci: diet tinggi minyak sawit, kolesterol, HDL, rasio kolesterol/ HDL</p><p>Abstract<br />The ratio of total cholesterol/ HDL is the lipoprotein variables best predict the risk of cardiovascular disease . The increased risk of cardiovascular disease can be caused by high levels of cholesterol exciting. …”
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22903
Preliminary study assessing the long-term surgical outcomes of TBX6-associated congenital scoliosis (TACS) patients using the propensity score matching method: exploring the clinic...
Published 2025-01-01“…Conclusions TACS patients had better surgical outcomes than NTACS patients, which means that genetic diagnosis of the TBX6 gene mutation in CS before surgery can help predict better surgical outcomes. The specific genetic mechanism is not yet clear and may be related to the relatively normal development of paravertebral tissues in TACS patients. …”
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22904
Prognostic value of body adipose tissue parameters in cancer patients treated with immune checkpoint inhibitors
Published 2025-02-01“…No significant relationship was found between TAT (HR: 0.81, 95% CI: 0.54–1.23, p = 0.332) and VSR (HR: 1.20, 95% CI: 0.95–1.51, p = 0.131) with PFS in ICI-treated patients.ConclusionThis study highlights the prognostic relevance of VAT and SAT in predicting treatment response and survival outcomes in cancer patients receiving ICIs. …”
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22905
China’s cultivated land threshold from the perspective of food security
Published 2024-12-01“…Furthermore, the minimum demand of China’s cultivated land in 2035 and 2050 was predicted based on the grain yield per unit cultivated area and population change. …”
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22906
The Impact of Nutritional Status and Tumor-Infiltrating Lymphocytes (CD4+ and CD8+) on Chemotherapy Response in Colorectal Cancer Patients
Published 2025-01-01“…These findings highlight the importance of supporting patients’ nutritional health during cancer treatment and suggest that monitoring immune cell activity could help predict treatment success. By tailoring care to these factors, healthcare providers may be able to improve outcomes for people with colorectal cancer.Keywords: chemotherapy response, colorectal cancer, prognostic, tumor infiltrating lymphocytes…”
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22907
Deep learning-based CT-free attenuation correction for cardiac SPECT: a new approach
Published 2025-02-01“…Methods We developed a feature alignment attenuation correction network (FA-ACNet) based on the 3D U-Net framework to generate predicted DL-based AC SPECT (Deep AC). The network was trained on 167 cardiac SPECT/CT studies using 5-fold cross validation and tested in an independent testing set (n = 35), with CTAC serving as the reference. …”
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22908
Application of dynamic systems modeling approach to rank optimal urban waste management strategies using SWOT method
Published 2024-06-01“…The reasons for using the dynamic systems approach for this research can also be enumerated as follows: 1) an appropriate approach in determining and predicting the effects of factors affecting waste production, 2) helping to understand the relationships between variables and examining the behaviour and structure of systems, incredibly complex systems (creating a conceptual model), 3) a flexible approach with the ability to analyze quantitatively and qualitatively, 4) the ability to review the system in the future under different scenarios and policies of decision makers and 5) dynamic system models are considered as simulation models; therefore, they have the advantages of using the simulation method over the analysis methods. …”
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22909
Enhancing Diagnostic Accuracy of Lung Nodules in Chest Computed Tomography Using Artificial Intelligence: Retrospective Analysis
Published 2025-01-01“…Evaluation metrics of this study include lung nodule detection rate, accuracy, false negative rate, false positive rate, and positive predictive value. The statistical analyses included descriptive statistics and chi-square, Cochran-Armitage, and Mann-Kendall tests. …”
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22910
ViTAU: Facial paralysis recognition and analysis based on vision transformer and facial action units
Published 2025-02-01“…By optimizing the mean squared error between the predicted and actual heatmaps, we can effectively identify the affected paralysis areas. …”
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22911
miR-149-3p Is a Potential Prognosis Biomarker and Correlated with Immune Infiltrates in Uterine Corpus Endometrial Carcinoma
Published 2022-01-01“…High miR-149-3p expression predicted poorer overall survival (OS) (HR: 2.56; 95% CI: 1.64–4.00; P<0.001), progression-free interval (PFI) (HR: 1.85; 95% CI: 1.29–2.65; P=0.001), and disease-specific survival (DSS) (HR: 2.33; 95% CI: 1.37–3.99; P=0.002). …”
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22912
Lokalisasi Mobile Robot berdasarkan Citra Kamera OMNI menggunakan Fitur Surf
Published 2020-10-01“…The number of closest features between the 360o image captured by the Omni camera and the reference image was the basis for determining location predictions. Image feature extraction uses the Speeded-Up Robust Features (SURF) method. …”
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22913
The Impact of the COVID-19 Pandemic on Oldest-Old Social Capital and Health and the Role of Digital Inequalities: Longitudinal Cohort Study
Published 2025-01-01“…ResultsCOVID-19 had a significant impact on social relationships (β=–4.35, 95% CI 6.38 to –2.32; P<.001), cultural activities (β=–.55, 95% CI –0.75 to –0.35; P<.001), cognitive functioning (β=–1.00, 95% CI –1.28 to –0.72; P<.001), depressive symptoms (β=.42, 95% CI 0.10-0.74; P=.009), physical health (β=.07, 95% CI 0.04-0.10; P<.001), and ICT use (β=–.11, 95% CI –0.18 to –0.03; P=.008). Internet use predicts reduced depressive symptoms (β=–.56, 95% CI –1.07 to –0.06; P=.03) over time. …”
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22914
The outcomes of residual ametropia correction by LASIK and PRK on pseudophakic eyes depending on IOL model
Published 2019-07-01“…<b>Background</b>: multiple studies discuss safety and predictability of laser refractive surgery to correct residual ametropia after IOL implantation. …”
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22915
The T4/T3 quotient as a risk factor for differentiated thyroid cancer: a case control study
Published 2017-04-01“…Few of these nodules harbour malignancy, thus further research is required to identify predictive markers of malignant thyroid disease. This study set out to understand the relationship between the levels of fT4 and fT3 and differentiated thyroid cancer. …”
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22916
Real-world study of phakic refractive lens for correction of high myopia
Published 2025-02-01“…Conclusions PRL implantation was a safe, efficient, predictable and stable method for correcting high myopia. …”
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22917
Exploring multi-level factors determining social participation of students with intellectual disabilities in inclusive physical education classes
Published 2025-01-01“…MLM was build up with SP (global value) as dependent variable and individual variables (L1) and class and teacher variables (L2) as predicting factors. Results SwID show a significant lower level of (SP) compared to their non-disabled PE classmates. …”
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22918
Prediksi Tipe Kepribadian MBTI Artis K-Pop Berdasarkan Caption Instagram Menggunakan Word2Vec dan Long-Short Term Memory (LSTM)
Published 2023-10-01“…The model is deployed in the Streamlit web application so that K-Pop fans can use it to predict the MBTI type by inputting Instagram captions. …”
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22919
Factors Influencing the Development of Metachronous Fractures in Patients with Osteoporotic Vertebral Fractures Treated with Conservative Management or Vertebroplasty
Published 2025-01-01“…We performed descriptive and contrastive bivariate analyses based on the presence of MFs and univariate and multivariate logistic regression analyses to obtain adjusted and crude odds ratios (aOR and cOR, respectively) for predicting MFs. Finally, we performed receiver-operating characteristic (ROC) curve analyses to determine the discriminative power of the models obtained. …”
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22920
miR-10a in Peripheral Blood Mononuclear Cells Is a Biomarker for Sepsis and Has Anti-Inflammatory Function
Published 2020-01-01“…Levels of miR-10a could distinguish between sepsis and infection and predict 28-day mortality. miR-10a plays an anti-inflammatory role in the pathogenesis of sepsis.…”
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