Mechanism of <italic>Coptis chinensis</italic> in Treatment of Type 2 Diabetes Mellitus Based on Network Pharmacology and Molecular Docking by LIU Huiling, TAN Dingying, HUANG Min, CHEN Pingping, ZHANG Wang

“…In addition, molecular docking was conducted between the core targets and the active ingredients of <italic>Coptis chinensis</italic> to verify the binding ability between the active ingredients and the core targets.Results① A total of 14 active ingredients of <italic>Coptis chinensis</italic>, 189 targets for the treatment of type 2 diabetes mellitus were screened out, among which 136 potential targets were identified, including 20 core targets (degree≥12), 137 signaling pathways with significant significance. ② Gene Ontology (GO) functional enrichment analysis showed that, the biological processes (BP) involved in the predicted target of <italic>Coptis chinensis</italic> in the treatment of type 2 diabetes mellitus involved gland development, epithelial cell proliferation, regulation of DNA-binding transcription factor activity, oxidative stress and apoptosis response to lipopolysaccharide, etc. …”
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Recent Advances of Surfactant-Polymer (SP) Flooding Enhanced Oil Recovery Field Tests in China by Chen Sun, Hu Guo, Yiqiang Li, Kaoping Song

“…Although laboratory tests showed that SP flooding can attain IORF of more than 15%, the average predicted IORF for these 10 field tests was 12% OOIP. …”
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Effect of environmental enrichment on relapse rates in patients with severe alcohol use disorder: protocol for a randomised controlled trial by Lila Barillot, Claudia Chauvet, Marc Besnier, Nematollah Jaafari, Marcello Solinas, Armand Chatard

“…Relapse will be defined as drinking at least five drinks per occasion or drinking at least five times a week. It is predicted that the group receiving the EE intervention will have a lower relapse rate than the control group. …”
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La ‘sofisticación’ como dimensión de cambio en el desarrollo epistemológico / “Sophistication” as a Dimension of Change in Developing a Personal Epistemology by Constanza Ruiz-Danegger, Yolanda Fernández-Acevedo, José Eduardo Moreno

“…“strong” character of belief development, and c) their correspondence with predictions from the literature. For their study on quantitative data, the following was suggested: a) MANOVA; b) a device to locate the beliefs in their continuum of meaning, and analyze their evolution; and c) to detail the shape and meaning of trajectories defined by the data set. …”
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Lake pulses driven by glacier melting and climate variability by Songtao Ai, Shoukat Ali Shah, Yi Cai, Jiajun Ling, Xinde Chu, Shijin Wang, Yuande Yang, Runchuan Ouyang, Jiachun An, Wolfgang Rack

“…Understanding glacier-fed hydrological systems is essential for predicting water availability and formulating climate adaptation strategies. …”
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Influence of minor hydrocarbon seepage on sulfur cycling in marine subsurface sediments by E. Schnabel, A. Vuillemin, C. C. Laczny, B. J. Kunath, A. R. Soares, A. J. Probst, R. Di Primio, J. Kallmeyer

“…The analysis of 50 gravity cores revealed significant variability in the predicted sulfate depletion depth, ranging from 3 to 12 m below the seafloor. …”
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Effect of supplementing phytase on piglet performance, nutrient digestibility and bone mineralisation by C. De Cuyper, L. Nollet, M. Aluwé, J. De Boever, L. Douidah, E. Vanderbeke, N. Outchkourov, S. Petkov, S. Millet

“…The statistical model predicted a linear increase for daily feed intake (DFI), ADG and BW with increased phytase increments. …”
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Evaluation of Left Atrial Function in Patients with Paroxysmal Atrial Fibrillation Using Left Atrial Automatic Myocardial Functional Imaging Ultrasonography by Hailan Liu, Lili Chen, Yan Song, Yingying Xu, Chunquan Zhang

“…The ROC curve revealed that the S_R was better than LAEF in predicting prognosis of patients with AF (AUC = 0.914, P < 0.0001 vs. …”
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Associations of Serum Cystatin C, DNAm Cystatin C, Renal Function, and Mortality in U.S. Adults by Yu-Wei Fang, Wei-Chung Huang, Chikang Wang, Chien-Yu Lin

“…Serum cystatin C is a well-established marker of renal function and a valuable predictor of health risks and mortality. DNA methylation-predicted cystatin C (DNAmCystatinC), an advanced epigenetic biomarker, serves as a proxy for serum cystatin C levels. …”
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Risk Index Model of Property and Cargo Insurance Claims Based on Precipitation in Hunan by Peng Weiying, Li Yueyong, Tan Shiqi, Li Hao, Guan Jianwen, Liao Chunhua, Zhou Wei, Xie Ruiheng

“…Results show a commendable accuracy rate of 72.3%, particularly strong in predicting instances of mild claims risk levels. Importantly, the model proves effective even in scenarios where meteorological rainstorm standards are not met, showcasing its reliability in preemptively identifying potential insurance claim risks.Presently, the developed risk index model has been implemented in Hunan Insurance Meteorological Disaster Risk Control Service Platform Version 2.0. …”
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Extent, Distribution, and Causes of Soil Acidity under Subsistence Farming System and Lime Recommendation: The Case in Wolaita, Southern Ethiopia by Fanuel Laekemariam, Kibebew Kibret

“…This study (1) investigates the extent and spatial distribution of soil acidity, (2) identifies factors attributing to soil acidification, and (3) predicts the lime requirement for major crops. A total of 789 soil samples were collected from arable lands in the Wolaita area which is mainly characterized by poor soil fertility and soil degradation in southern Ethiopia. …”
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Disrupting of IGF2BP3-stabilized CLDN11 mRNA by TNF-α increases intestinal permeability in obesity-related severe acute pancreatitis by Lihui Lin, Yansong Lin, Xianwen Guo, Ruoyi Zhang, Xin Ling, Zewen Zhang, Rong Lin, Zhen Ding

“…The interaction between CLDN11 mRNA and insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) protein was predicted through bioinformatics analysis and validated by RNA immunoprecipitation and RNA pull-down assay. …”
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Capital formation and production of carbon emissions in low-carbon development by E.S. Siregar, S.U. Sentosa, A. Satrianto

“…Low carbon development is a new platform to maintain economic growth through reducing carbon emissions and reducing the use of natural resources, because it was predicted that reducing emissions will increase economic growth while preventing forest loss, improving air quality and living standards, and reducing mortality rates.METHODS: Utilizing a quantitative method, this study integrates a novel viewpoint by combining low-carbon development with related emission factors. …”
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Predictors of failure of DISE-directed adenotonsillectomy in children with sleep disordered breathing by Noura Alsufyani, Andre Isaac, Manisha Witmans, Paul Major, Hamdy El-Hakim

“…Several DISE findings can independently predict AT failure, including tonsil size, degree of chronic rhinitis, and the presence of a deviated nasal septum, and can be addressed at a second stage. …”
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Patient characteristics and predictors of mortality among children hospitalised with tuberculosis: A six-year case series study in Uganda. by Pauline Mary Amuge, Greta Lassance Becker, Rogers Nelson Ssebunya, Esther Nalumansi, Alex Adaku, Michael Juma, Jay Brooks Jackson, Adeodata Rukyarekere Kekitiinwa, Peter James Elyanu, Eric Wobudeya, Robert Blount

“…Hospitalisation in the urban hospital predicted a 0.48-day increase in natural log-transformed length of hospital stay (ln-length of stay) (95% CI 0.15-0.82, p = 0.005), but not age, sex, HIV, malnutrition, or TB meningitis.…”
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Incidence, trends and patterns of female breast, cervical, colorectal and prostate cancers in Antigua and Barbuda, 2017–2021: a retrospective study by Andre A. N. Bovell, Thendo Ramaliba, Sekeena O. Goodwin, Joycelyn C. Phillip, Jabulani Ncayiyana, Themba G. Ginindza

“…Female breast and prostate cancers were the dominant cancer types in terms of incidence, age-standardized incidence and predicted increasing incidence trends. Variableness in cancer-specific age-standardized rates across parishes and years of presentation were observed. …”
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Optimizing risk in action: Differences between fixated aim points and movement outcomes in throwing by Stephan Zahno, Damian Beck, Ralf Kredel, André Klostermann, Ernst-Joachim Hossner

“…Models of statistical decision theory (Trommershäuser et al., 2008) predict that the optimal aim point horizontally shifts away from the centre of the target circle as soon as the penalty is non-zero. …”
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Managing cardiovascular events, hyperglycemia, and obesity in type 2 diabetes through microRNA regulation linked to glucagon-like peptide-1 receptor agonists by Xiaolei Miao, Maryam Davoudi, Zahra Alitotonchi, Ensieh Sadat Ahmadi, Fatemeh Amraee, Ashraf Alemi, Reza Afrisham

“…Results GLP-1RAs modify the expression of miRNAs involved in endothelial function, sugar metabolism, and adipogenesis, including but not limited to miR-27b, miR-130a, and miR-210. Baseline miR-15a-5p predict weight loss, while higher miR-378-3p and miR-126-3p levels are related to better glycemic control and lower HbA1c and FPG at one year post-treatment. miR-375-5p was also reported as a predictor of HbA1c levels. …”
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Optimization Analysis of Mechanical Properties of Fly Ash-Based Multicontent Gasification Slag Paste Filling Material by Denghong Chen, Tianwei Cao, Ran Chen, Chao Li

“…The central combination design is used to predict that the mix proportion of X1 is 84%, X2 is 15%, X3 is 1 : 5, and X4 is 7%, the content of coal gangue is 10%, and the content of furnace bottom slag is 5% which is the best. …”
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Effects of respiratory sarcopenia on the postoperative course in elderly lung cancer patient: a retrospective study by Dong Jae Han, Kwon Joong Na, Taeyoung Yun, Ji Hyeon Park, Bubse Na, Samina Park, Hyun Joo Lee, In Kyu Park, Chang Hyun Kang, Young Tae Kim

“…These findings suggest that other factors, such as DLCO and male sex, may play a more prominent role in predicting respiratory complications.…”
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