Development of a zoonotic influenza distribution assessment and ranking system (ZIDAR): Technical application in Nepal to support cross-sectoral risk-based surveillance by Adam Charette-Castonguay, Dipendra Gautam, Binay Shrestha, Hemant Chandra Ojha, Barun Kumar Sharma, Mukul Upadhayaya, Sujan Rana, Roshika Shrestha, Lok Bandu Chaudhary, Bhawana Kandel, Rudra Prasad Marasini, Sharmila Chapagain, Tulsi Ram Gompo, Surendra Karki, Apsara Poudel, Saugat Shrestha, Avinash Sunny Kayastha, Arun Kumar Govindakarnavar, Reuben Samuel, Allison Gocotano, Pushpa Ranjan Wijesinghe, Nilesh Buddha, Edwin Ceniza Salvador, Manish Kakkar, Ricardo J. Soares Magalhães

“…The ZIDAR Nepal model's predictive accuracy, determined by the area under the receiver operating characteristic curve, demonstrated strong performance: 0.87 and 0.85 for the wildlife and animal components, respectively. …”
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Bis(7)-harmine derivatives as potential multi-target anti-Alzheimer agents by Hongtao Du, Hongtao Du, Hongtao Du, Fang Ma, Fang Ma, Yuanyuan Cao, Miaoyan Bai, Xinyi Gao, Ziyi Yang, Yang Xu, Yan Yan, Yan Yan

“…Importantly, the multitarget compounds 6d, 8c, and 8d exhibited remarkable efficacy in simultaneously mitigating Aβ-induced toxicity in SH−SY5Y cells while demonstrating minimal cytotoxicity. Furthermore, predicted ADMET results suggested that 6d, 8c, and 8d possessed favorable pharmacokinetic properties and demonstrated low toxicity levels. …”
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Exploring fatigue in Marfan and hypermobile Ehlers-Danlos syndromes: an analytical cross-sectional study in two Italian healthcare centres by Rosario Caruso, Alessandro Pini, Gianluca Conte, Arianna Magon, Irene Baroni, Edward Callus, Nathasha Udugampolage, Jacopo Taurino, Alessandra Bassotti, Giada De Angeli, Giulia Paglione, Giuliana Trifirò

“…In the overall sample, hEDS significantly predicted fatigue (B=0.430, p=0.022), with depression and insomnia as strong influencers (PHQ-9: B=0.12, p<0.001; ISI: B=0.092, p<0.001). …”
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Adolescents with Persistent Symptoms Following Acute SARS-CoV-2 Infection (Long-COVID): Symptom Profile, Clustering and Follow-Up Symptom Evaluation by Marco Floridia, Danilo Buonsenso, Laura Macculi, Liliana Elena Weimer, Marina Giuliano, Flavia Pricci, Leila Bianchi, Domenico Maurizio Toraldo, Graziano Onder, The ISS Long-COVID Study Group

“…Polisymptomaticity may predict long-term persistence.…”
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Spatio-temporal evolution and simulation of soil salinization in typical oasis water-saving irrigation area based on long series data by Wenhao Li, Shuanglong Gao, Dongjie Pei, Yue Wen, Xiaoguo Mu, Mengjie Liu, Zhenhua Wang

“…A geographically weighted regression (GWR) model was employed to predict the distribution of soil salinization at the irrigation scale. …”
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Extracellular acyl-CoA-binding protein as an independent biomarker of COVID-19 disease severity by Stephane Isnard, Stephane Isnard, Tsoarello Mabanga, Tsoarello Mabanga, Léna Royston, Léna Royston, Léna Royston, Carolina A. Berini, Carolina A. Berini, Simeng Bu, Simeng Bu, Orthy Aiyana, Orthy Aiyana, Hansen Feng, Hansen Feng, Bertrand Lebouché, Bertrand Lebouché, Bertrand Lebouché, Bertrand Lebouché, Cecilia T. Costiniuk, Cecilia T. Costiniuk, Joseph Cox, Joseph Cox, Guido Kroemer, Guido Kroemer, Guido Kroemer, Madeleine Durand, Jean-Pierre Routy, Jean-Pierre Routy, Jean-Pierre Routy, the Biobanque Québécoise de la COVID-19 (BQC-19)

“…BackgroundFactors leading to severe COVID-19 remain partially known. New biomarkers predicting COVID-19 severity that are also causally involved in disease pathogenesis could improve patient management and contribute to the development of innovative therapies. …”
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Affective valence predictors from real-world based short sprint interval training by Stefano Benítez-Flores, Flávio A. de S. Castro, Eduardo Caldas Costa, Daniel Boullosa, Todd A. Astorino

“…These findings suggest that HR-based measures, particularly those related to in-task stress (time ≥ 90% HRpeak) and acute recovery (ΔHRRend-120s end, and RMSSDend), may predict affective valence during real-world sSIT.…”
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Loss of MTAP expression is strongly linked to homozygous 9p21 deletion, unfavorable tumor phenotype, and noninflamed microenvironment in urothelial bladder cancer by Natalia Gorbokon, Niklas Wößner, Viktoria Ahlburg, Henning Plage, Sebastian Hofbauer, Kira Furlano, Sarah Weinberger, Paul Giacomo Bruch, Simon Schallenberg, Florian Roßner, Sefer Elezkurtaj, Maximilian Lennartz, Niclas C Blessin, Andreas H Marx, Henrik Samtleben, Margit Fisch, Michael Rink, Marcin Slojewski, Krystian Kaczmarek, Thorsten Ecke, Tobias Klatte, Stefan Koch, Nico Adamini, Sarah Minner, Ronald Simon, Guido Sauter, Henrik Zecha, David Horst, Thorsten Schlomm, Lukas Bubendorf, Martina Kluth

“…MTAP deficiency has been proposed as a marker for predicting targeted treatment response. A tissue microarray including 2,710 urothelial bladder carcinomas were analyzed for 9p21 deletion by fluorescence in situ hybridization and MTAP expression by IHC. …”
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School-to-work and school-to-university transition and health inequalities among young adults: a scoping review by Matthias Richter, Nico Dragano, Benjamin Wachtler, Stephanie Hoffmann, Max Herke, Katharina Diehl, Marvin Reuter, Paula Mayara Matos Fialho, Maria-Inti Metzendorf, Wiebke Schüttig, Christian Deindl, Sarah Schleberger, Claudia R Pischke

“…Disadvantaged family SEP negatively impacted on mental health and predicted an adverse weight development. There was limited evidence for the outcomes physical/somatic symptoms and self-rated health. …”
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The impact of margins and re‐resection in pediatric synovial sarcoma by Andres F. Espinoza, Priya B. Shetty, Jillian C. Jacobson, Hannah Todd, Kelley Harrell, Alfred F. Trappey, John Doski, Eumenia C. Castro, Nicole I. Montgomery, M. Fatih Okcu, Rajkumar Venkatramani, Dai H. Chung, Sanjeev A. Vasudevan

“…We sought to evaluate the adequate resection margin and the role of re‐resection in predicting outcomes in children with synovial sarcomas. …”
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Ferula communis leaf extract: antioxidant capacity, UHPLC–MS/MS analysis, and in vivo and in silico toxicity investigations by Imad Ed-Dahmani, Mohamed El Fadili, Ghizlane Nouioura, Fahd Kandsi, Yassine El Atki, Hatem A. Abuelizz, Raffaele Conte, Fatima Zahra Lafdil, Abdeslam Taleb, Abdelfattah Abdellaoui, Mustapha Taleb

“…UHPLC–tandem mass spectrometry (MS/MS) analysis of the extract highlights the presence of 11 compounds, the most abundant of which is p-hydroxybenzoic acid, representing 53.65%. The predicted pharmacokinetic characteristics of absorption, distribution, metabolism, excretion, and toxicity (ADMET) attest to the well-absorbed nature of the isolated compounds, with human intestinal absorption (HIA) varying from 42% for arbutin (M3) to 100% for ursolic acid (M4).ConclusionIn conclusion, the leaves of Ferula communis are a good source of natural antioxidants and phenolic compounds. …”
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Genome-Wide Association Study of Bone Mineral Density in Korean Men by Ye Seul Bae, Sun-Wha Im, Mi So Kang, Jin Hee Kim, Soon Hang Lee, Be Long Cho, Jin Ho Park, You-Seon Nam, Ho-Young Son, San Deok Yang, Joohon Sung, Kwang Ho Oh, Jae Moon Yun, Jong Il Kim

“…Bone mineral density (BMD), a highly heritable trait, has been proven a useful diagnostic factor in predicting fracture. Because medical information is lacking about male osteoporotic genetics, we conducted a genome-wide association study of BMD in Korean men. …”
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Association between Admission Hyperglycemia and Culprit Lesion Characteristics in Nondiabetic Patients with Acute Myocardial Infarction: An Intravascular Optical Coherence Tomograp... by Jinying Zhou, Zhaoxue Sheng, Chen Liu, Peng Zhou, Jiannan Li, Runzhen Chen, Li Song, Hanjun Zhao, Hongbing Yan

“…A/C>1.22 but not ABG>140 mg/dl predicted a high prevalence of plaque rupture, lipid-rich plaque, and TCFA in non-DM patients. …”
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Analysis of the diagnostic efficacy of ultrasound, MRI, and combined examination in benign and malignant breast tumors by Dianpei Ma, Dianpei Ma, Changliang Wang, Jie Li, Jie Li, Xiaohan Hao, Yun Zhu, Zhizhen Gao, Zhizhen Gao, Chun Liu, Changfan Luo, Yu Huang

“…The diagnostic accuracy of US, MRI, and their combined use in differentiating benign and malignant tumors was evaluated.ResultsThe combined examination demonstrated the highest area under the curve (AUC), sensitivity, and negative predictive value (NPV) (0.904, 90%, 90.4%), outperforming US (0.830, 73.3%, 78.6%) and MRI (0.897, 89.7%, 88.8%). …”
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Postoperative Tongqi Formula ameliorates postoperative ileus via p38 MAPK signaling pathway and metabolic disorder by Mengmeng Yang, Yuxuan Lu, Shufan Jin, Wanqiu Liu, Miaoshi Yao, Zhiwei Jiang, Yachun Shu

“…The identified compounds subsequently employed network pharmacology to predict the signaling pathways associated with the inflammatory phase of POI. …”
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The process of nitrogen-adaptation root endophytic bacterial rather than phosphorus-adaptation fungal subcommunities construction unveiled the tomato yield improvement under long-t... by Xiaoxia Li, Xiaoxia Li, Xiaoxia Li, Muhammad Awais, Muhammad Awais, Muhammad Awais, Shuang Wang, Shuang Wang, Shuang Wang, Shuang Wang, Zhu Zhang, Zhu Zhang, Zhu Zhang, Shuning Zhao, Shuning Zhao, Shuning Zhao, Yufeng Liu, Yufeng Liu, Yufeng Liu, Zhouping Sun, Zhouping Sun, Zhouping Sun, Hongdan Fu, Hongdan Fu, Hongdan Fu, Tianlai Li, Tianlai Li, Tianlai Li

“…Nitrogen-adapting abundant and rare bacterial subcommunities provided a stronger predictive correlation for tomato yield than phosphorus-adapting fungal subcommunities. …”
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Genome-wide identification of MGT gene family in soybean (Glycine max) and their expression analyses under magnesium stress conditions by Ammar Anwar, Junaid Akhtar, Saba Aleem, Maida Aleem, Muhammad Khuram Razzaq, Saud Alamri, Qasim Raza, Iram Sharif, Arooj Iftikhar, Shehreen Naseer, Zaheer Ahmed, Iqrar Ahmed Rana, Waheed Arshad, Muhammad Imran Khan, Javaid Akhter Bhat, Muqadas Aleem, Abdel-Rhman Z. Gaafar, Mohamed S. Hodhod

“…The expansion of the GmMGT members in NIPA and MRS2/MGT was predicted, while CorA was identified as the most conserved group in G. max. …”
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Rosiglitazone, a Ligand to PPARγ, Improves Blood Pressure and Vascular Function through Renin-Angiotensin System Regulation by María Sánchez-Aguilar, Luz Ibarra-Lara, Leonardo Del Valle-Mondragón, María Esther Rubio-Ruiz, Alicia G. Aguilar-Navarro, Absalom Zamorano-Carrillo, Margarita del Carmen Ramírez-Ortega, Gustavo Pastelín-Hernández, Alicia Sánchez-Mendoza

“…The in silico analysis is a valuable tool to predict the interaction between PPARγ and RAS.…”
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Influence of ESBL colonization status on gut microbiota composition during allogenic hematopoietic stem cell transplantation by Silvia Corcione, Ilario Ferrocino, Tommaso Lupia, Alessandro Busca, Gabriele Bianco, Chiara Dellacasa, Luisa Giaccone, Lucia Brunello, Sara Butera, Cristina Costa, Benedetto Bruno, Francesco Giuseppe De Rosa

“…From a clinical perspective, the evolution of this prospective pilot study will be to investigate markers of gut barrier functions, SCFA productions and to correlate the predictivity of these parameters with risk of invasive infections and clinical outcomes in allo-HSCT population.…”
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Analysis of ecological network evolution in an ecological restoration area with the MSPA-MCR model: A case study from Ningwu County, China by Ziyan Guo, Chuxin Zhu, Xiang Fan, Muye Li, Nuo Xu, Yuan Yuan, Yanjun Guan, Chunjuan Lyu, Zhongke Bai

“…Ecological network construction has been conducted in various areas worldwide at different spatial scales, to guide regional ecological conservation and restoration, or predict future ecological networks under different land use scenarios. …”
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