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22421
Impact of Food Physical Properties on Oral Drug Absorption: A Comprehensive Review
Published 2025-01-01“…In addition, we introduced the practical application of physiologically based pharmacokinetic (PBPK) modeling in predicting oral drug absorption under the influence of food Properties.Plain language summary: In the development of new drugs, understanding how food affects drug absorption is crucial. …”
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22422
Potential of right ventricular function assessment with echocardiography in transcatheter aortic valve replacement:
Published 2024-12-01“…Intraoperative RVFWLS has the potential to predict postoperative new occurrence of BBB or CAVB.…”
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22423
Mapping Habitat Structures of Endangered Open Grassland Species (<i>E. aurinia</i>) Using a Biotope Classification Based on Very High-Resolution Imagery
Published 2025-01-01“…We generated habitat suitability models (HSM) to gain insights into the spatial factors influencing the occurrence of <i>E. aurinia</i> and to predict potential habitat suitability for the whole study site. …”
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22424
Solar Energy Forecasting Framework Using Prophet Based Machine Learning Model: An Opportunity to Explore Solar Energy Potential in Muscat Oman
Published 2025-01-01“…Nevertheless, with the advancement in the field of artificial intelligence (AI), one can predict the availability of solar and wind energy in the short, medium, and long term with fairly high accuracy. …”
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22425
Clinical Profile and Prescription Patterns in Culture-proven Enteric Fever in Children
Published 2024-03-01“…Most cases had normal leukocyte counts, eosinopenia, and elevated CRP. CRP does not predict fever defervescence. Fever typically resolved in 4–5 days, with paratyphoid fever resolving earlier. …”
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22426
Elexacaftor/tezacaftor/ivacaftor and inflammation in children and adolescents with cystic fibrosis: a retrospective dual-center cohort study
Published 2025-02-01“…Data on immunoglobulins (Ig) (A, G, and M), γ-globulin, leukocyte levels, percent predicted forced expiratory volume in the first second (ppFEV1), sweat chloride (SC) concentration, and sputum cultures were collected at baseline, 12, and 24 months of treatment. …”
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22427
Model-based fed-batch cultivation of Viola odorata plant cells exhibiting antimalarial and anticancer activity
Published 2025-01-01“…In addition, bioreactor-cultivated biomass extracts (aqueous/alcoholic) were tested for various bioactivities like hemolytic, cytotoxic, anti-inflammatory, and antiplasmodial.ResultsExperimental validation of the fed-batch model-predicted strategy resulted in a two-fold enhancement in biomass production (32.2 g DW L−1) at the bioreactor level. …”
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22428
Comprehensive characterization of high-risk coding and non-coding single nucleotide polymorphisms of human CXCR4 gene.
Published 2024-01-01“…In this investigation, the tools SIFT, PROVEAN, PolyPhen-2, PANTHER, SNAP 2.0, PhD-SNP, and SNPs&GO were used to predict potentially harmful and disease-causing nsSNPs in CXCR4. …”
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22429
Association between Axial Length to Corneal Curvature Radius Ratio and Myopia in Adult Patients
Published 2024-01-01“…The association between AL and AL/CR of the eye and SE was analyzed by multiple linear regression. Also, the predictive ability of AL/CR for high myopia was investigated by ROC curve. …”
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22430
A new risk assessment model of venous thromboembolism by considering fuzzy population
Published 2024-12-01“…Many studies using machine learning (ML) models to predict VTE risk overlook the impact of class-imbalance problem due to the low incidence rate of VTE, resulting in inferior and unstable model performance, which hinders their ability to replace the Padua model, a widely used linear weighted model in clinic. …”
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22431
Preparation, Purification, Identification and Anti-lipid Oxidation of Kidney Bean Skin Polyphenols
Published 2025-01-01“…Using a model, it was calculated that peanut oil mixed with polyphenols-vitamin C had a maximum shelf life of 193.4 d at 20 ℃, control group was 150.3 d, with a maximum relative error of 8.7% compared to measured values, accurately predicting the shelf life of the edible oil. In conclusion, kidney bean skin polyphenols had strong antioxidant properties and potential as a safe natural food antioxidant.…”
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22432
A leap forward: exploring the advantages of single-step genome evaluation in Italian Mediterranean buffalo
Published 2023-11-01“…These results showed that implementing ssGBLUP in the breeding program can generate more accurate predictions for important traits in dairy IMB than traditional BLUP. …”
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22433
Identification of SETD4 as an Onco‐Immunological Biomarker Encompassing the Tumor Microenvironment, Prognoses, and Therapeutic Responses in Various Human Cancers
Published 2025-01-01“…The upregulation of SETD4 may be a prognostic risk factor predicting poor overall survival and progression‐free survival. …”
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22434
Associations between health, productive performance and oral fluid biomarkers in commercial pig farms
Published 2024-12-01“…Conclusions Haptoglobin, procalcitonin, oxytocin, creatine kinase and alpha-amylase, measured in oral fluid, should be further studied as good candidates to assess pig herds and predict performance at a batch level, through a non-invasive approach. …”
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22435
Comprehensive bioinformatics analysis identifies hub genes associated with immune cell infiltration in early-onset schizophrenia
Published 2025-01-01“…Regulatory miRNAs for the hub genes were predicted using miRNet, and the correlation between mRNAs and miRNAs was analyzed and validated in clinical samples. …”
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22436
Identification and Analysis of Potential Immune-Related Biomarkers in Endometriosis
Published 2023-01-01“…Therefore, there is an urgent need to identify reliable biomarkers for early detection and accurate diagnosis to predict clinical outcomes and aid in the early intervention of endometriosis. …”
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22437
Homologous recombination deficiency test validation in patients with high-grade advanced ovarian cancer
Published 2025-02-01“…BackgroundAlong with BRCA mutation status, homologous recombination deficiency (HRD) testing is a prognostic and predictive biomarker for poly-ADP-ribose polymerase (PARP) inhibitor therapy indication in high-grade epithelial ovarian, fallopian tube, or peritoneal cancer. …”
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22438
The serum level of sclerostin decreases in radiographic axial spondyloarthritis patients with fatty lesions
Published 2025-01-01“…Serum sclerostin might be useful as a biomarker to predict the progression of the chronic inflammation in SIJs in r-axSpA.…”
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22439
Enablers of and barriers to ART adherence among female sex workers in mid-western Uganda: a qualitative study
Published 2025-01-01“…., food scarcity), and occupation-related factors (substance use, incarceration, busy and predictable schedules, and abrupt migrations) were the additional barriers to ART adherence. …”
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22440
A Potential Protective Effect of Alcohol Consumption in Male Genital Lichen Sclerosus: A Case-Control Study
Published 2023-01-01“…No significant differences in sociodemographic characteristics (age and BMI) were found between the two compared groups. Smoking cannot predict LSc as opposed to alcohol consumption, which we found to be a protective factor against the appearance of LSc (p=0.027). …”
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