-
21901
Genetic and Plasma Proteomic Approaches to Identify Therapeutic Targets for Graves’ Disease and Graves’ Ophthalmopathy
Published 2025-02-01“…Then, downstream analyses were performed to detect protein interactions, gene function, cell type-specific expression and druggable information.Results: This study genetically predicted levels of 62 plasma proteins were associated with GD risk. …”
Get full text
Article -
21902
Investigating the characteristics and needs of frequently admitting hospital patients: a cross-sectional study in the UK
Published 2020-09-01“…Objectives This study forms the user requirements phase of the OPTIMAL project, which, through a predictive model and supportive intervention, aims to decrease early hospital readmissions. …”
Get full text
Article -
21903
Correlation between estimated glucose disposal rate, insulin resistance, and cardiovascular mortality among individuals with metabolic syndrome: a population-based analysis, eviden...
Published 2025-01-01“…Methods A total of 8215 subjects with MetS screened from the National Health and Nutrition Examination Survey (NHANES) during the period from 1999 to 2018 were evaluated for the predictive value of eGDR for CVD and all-cause mortality. …”
Get full text
Article -
21904
Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios Are Correlated with Complicated Diverticulitis and Hinchey Classification: A Simple Tool to Assess Disease Severity in th...
Published 2019-01-01“…The aim of our study was to determine the role of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in predicting severity of diverticulitis as assessed by Hinchey classification. …”
Get full text
Article -
21905
The accuracy of anthropometric indices in detecting hypertension in Sudanese adults: a cross-sectional study
Published 2025-01-01“…Conclusion BMI, WC, and WHtR showed moderate predictive power, suggesting that these indices have a limited role in diagnosing hypertension at the individual level and are more appropriate for population screening than for individual diagnosis. …”
Get full text
Article -
21906
The Loge GDR Was Strongly Associated with NAFLD as a Predictor in Normoalbuminuric Patients with Type 2 Diabetes
Published 2025-01-01“…In recent years, many surrogate markers of IS have emerged to predict NAFLD. A natural log transformation of the glucose disposal rate (loge GDR) has been proposed as a new model for IS in patients with T2D. …”
Get full text
Article -
21907
A longitudinal study of the association between the outcome of bariatric surgery and mental health indicators in Chinese patients: an examination of the interaction effect
Published 2025-02-01“…In multiple linear regression models, the TDQ-by-follow-up duration interaction was predictive of the %TWL, and both married status and the level of tertiary education were identified as negatively associated factors. …”
Get full text
Article -
21908
Enhancing cotton irrigation with distributional actor–critic reinforcement learning
Published 2025-02-01“…Accurate predictions of irrigation’s impact on crop yield are crucial for effective decision-making. …”
Get full text
Article -
21909
Assessing Soil Erosion by Agricultural and Forestry Production and Proposing Solutions to Mitigate: A Case Study in Son La Province, Vietnam
Published 2018-01-01“…Application of GIS technology and the Universal Soil Loss Equation (USLE) to predict soil erosion showed that the soil eroded at a very low level (0–1 ton·ha−1·year−1) accounted for the largest proportion with 56.49% of the area. …”
Get full text
Article -
21910
Association of dysautonomia and different risk factors in patients with Guillain-Barré syndrome in a tertiary hospital in the Philippines
Published 2025-01-01“…Although GBS patients with dysautonomia had longer hospital stay (12.33 days), it only predicts 5.5% of the variability. Discussions The prevalence of cardiovascular manifestations was postulated from cardiosympathetic hyperactivity between arterial baroreceptors, cardiac parasympathetic fibers, and preganglionic sympathetic vasomotor fibers. …”
Get full text
Article -
21911
RETRACTED ARTICLE: Effect of Oroxylum indicum on hepatocellular carcinoma via the P53 and VEGF pathways based on microfluidic chips
Published 2023-11-01“…According to the P53 and VEGF pathways predicted by network pharmacology, RT‒qPCR and immunofluorescence staining experiments were conducted. …”
Get full text
Article -
21912
Elevational ranges of pioneer marsh species are site specific and likely shaped by different abiotic and biotic factors
Published 2025-01-01“…Knowledge about species‐specific responses to their abiotic and biotic environment is an important prerequisite for modeling and predicting future ecosystem shifts in salt marshes under climate change.…”
Get full text
Article -
21913
Short-Term and Long-Term Effects of Bariatric Surgery on Diabetic Retinopathy: A Systematic Review
Published 2025-01-01“…Further studies should explore additional risk factors to better predict DR outcomes post-surgery. <i>Conclusions</i>: BS improves weight management, blood pressure, and diabetes control, potentially benefiting DR. …”
Get full text
Article -
21914
Editorial: The Artificial Intelligence in Translational Medicine and Biomedical Research, How Future Can be Shaped?!!
Published 2023-12-01“…The AI and ML are becoming so intelligent to an extent not to only diagnose the disease but also predict disease prognosis in future. The narrow AI (WatsonX) that was introduced by the IBM company can play a major role in assisting clinical decisions and image analysis. …”
Get full text
Article -
21915
Skin Microbiota: Mediator of Interactions Between Metabolic Disorders and Cutaneous Health and Disease
Published 2025-01-01“…Advances in metabolomics and microbiome sequencing have unveiled critical biomarkers, such as short-chain fatty acids and microbial signatures, predictive of therapeutic outcomes. For example, elevated butyrate levels in psoriasis have been associated with reduced Th17-mediated inflammation, while the presence of specific Lactobacillus strains has shown potential to modulate immune tolerance in atopic dermatitis. …”
Get full text
Article -
21916
Polymorphism of renin — angiotensin system genes in progression of liver fibrosis in patients with chronic hepatitis C
Published 2014-08-01“…Carriage of mutant alleles of angiotensinogen gene on any of loci (G-6A or M235T) is the factor predicting more rapid progression of disease. As chronic hepatitis C is multifactorial disease, it is rational to use testing of allelic variants of angiotensinogen gene in patient-specific approach at CHC management.…”
Get full text
Article -
21917
<i>Lin28b-let-7</i> Modulates mRNA Expression of <i>GnRH1</i> Through Multiple Signaling Pathways Related to Glycolysis in GT1-7 Cells
Published 2025-01-01“…In this study, the mRNA expression levels of <i>Lin28b</i> and <i>let-7</i> in the pubertal and juvenile goat hypothalamus and pituitary gland were detected, and <i>Lin28b</i> expression in the pubertal hypothalamus decreased significantly compared with that in juvenile tissues. It was predicted that <i>Lin28b</i> might inhibit <i>GnRH1</i> expression, which was verified in the GnRH-producing cell model GT1-7 cells. …”
Get full text
Article -
21918
MiR-595 and Cldnd1: Potential related factors for bone loss in postmenopausal women with hip osteoporotic fracture.
Published 2024-01-01“…Using miR-595 (highest |log2 FC|) as the subject of subsequent research. 3542 targeted mRNAs were predicted from TargetScan and 362 were from miRDB. 337 TGs were intersected, which were mainly enriched in nucleus. …”
Get full text
Article -
21919
Determinants of Microbial Contamination of Street-Vended Chicken Products Sold in Nairobi County, Kenya
Published 2020-01-01“…The vendor practices and environmental hygiene of the vending place would not significantly (p>0.05) predict contamination with Campylobacter and Staphylococcus. …”
Get full text
Article -
21920
Dextran sodium sulfate-induced colitis alters the proportion and composition of replicating gut bacteria
Published 2025-01-01“…Lastly, we show that colitis development is positively correlated with increases in the presence and abundance of bacteria in situ which are predicted to be fast replicators. This could suggest that taxa with the potential to replicate quickly may have an advantage during intestinal inflammation. …”
Get full text
Article