Insights from Dysregulated mRNA Expression Profile of β-Cells in Response to Proinflammatory Cytokines by Zhen Wang, Kunlin Huang, Jing Xu, Jia Liu, Ying Zheng

“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) biological pathway analyses were performed to predict the functions of dysregulated genes. The networks of circRNA-mRNA were constructed between differentially mRNAs and dysregulated expressed circRNAs in our previous study. …”
Get full text

Serum stromal cell-derived factor 1α as a prognostic indicator in elderly patients with acute myeloid leukemia receiving CAG-based chemotherapy by Zhenzhen Wang, Jing Yuan, Nan Zhou, Jianfeng Zhang

“…ROC analysis further highlighted the predictive capability of serum SDF-1α for chemotherapy responsiveness. …”
Get full text

Validation of a paediatric sepsis screening tool to identify children with sepsis in the emergency department: a statewide prospective cohort study in Queensland, Australia by Paula Lister, Kristen Gibbons, Luregn J Schlapbach, Adam Irwin, Michael Rice, Sainath Raman, Amanda Harley, Patricia Gilholm

“…We assessed the performance of the paediatric sepsis screening tool using stepwise multiple logistic regression analyses with 10-fold cross-validation and evaluated the final model at defined risk thresholds.Setting Twelve emergency departments (EDs) in Queensland, Australia.Participants 3473 children screened for sepsis, of which 523 (15.1%) were diagnosed with sepsis.Interventions A 32-item paediatric sepsis screening tool including rapidly available information from triage, risk factors and targeted physical examination.Primary outcome measure Senior medical officer-diagnosed sepsis combined with the administration of intravenous antibiotics in the ED.Results The 32-item paediatric sepsis screening tool had good predictive performance (area under the receiver operating characteristic curve (AUC) 0.80, 95% CI 0.78 to 0.82). …”
Get full text

RNA sequence analysis landscape: A comprehensive review of task types, databases, datasets, word embedding methods, and language models by Muhammad Nabeel Asim, Muhammad Ali Ibrahim, Tayyaba Asif, Andreas Dengel

“…It streamlines the development of new predictors by providing a comprehensive survey of 58 word embeddings and 70 language models based predictive pipelines performance values as well as top performing traditional sequence encoding based predictors and their performances across 47 RNA sequence analysis tasks.…”
Get full text

Identification of tacrolimus-related genes in familial combined hyperlipidemia and development of a diagnostic model using bioinformatics analysis by Yuan Xu, Hongfei He, Haiyang Li

“…To this end, we investigated the potential genes associated with tacrolimus metabolism in familial combined hyperlipidemia (FCHL) to identify relevant biomarkers of FCHL, develop predictive diagnostic models for hyperlipidemia, and reveal potential therapeutic targets for FCHL. …”
Get full text

Prevalence and associated factors of healthy aging among community-dwelling older adults in Lishui city, China: a cross-sectional study by Jian-Hua Chen, Norhasmah Mohd Zain, Azlina Yusuf, Bi-He Ying

“…Both individual-environment interaction factors as better HSM ability as well as SPHA might help predict older adults’ healthy aging in mountainous areas in China. …”
Get full text

THEORY AND PRACTICE OF ACADEMIC STUDENT EXCHANGES AND CO-OPERATION BETWEEN CHINESE AND RUSSIAN UNIVERSITIES by Li Wenze

“…This paper analyses the current situation and predicts future directions of educational exchange through various prisms, including the experience of academic student exchange between universities in the two countries. …”
Get full text

Constructing age-structured matrix population models for all fishes by Masami Fujiwara

“…By integrating extensive databases and predictive tools, this study offers a scalable approach for developing matrix population models across diverse fish species. …”
Get full text

Survival outcomes of marijuana users in p16 positive oropharynx cancer patients by Han Zhang, Michael Xie, Marc Levin, Stuart D. Archibald, B. Stanley Jackson, J. E. M. Young, Michael K. Gupta

“…Univariate logistic regression analysis showed that age, gender, and cT-Stage were predictive of disease recurrence within both groups (p < 0.05). …”
Get full text

In Vitro Antibacterial and Antioxidant Activities, Pharmacokinetics, and In Silico Molecular Docking Study of Phytochemicals from the Roots of Ziziphus spina-christi by Hadush Gebrehiwot, Urgessa Ensermu, Aman Dekebo, Milkyas Endale, Tariku Nefo Duke

“…Furthermore, the organ toxicity predictions showed that all the compounds exhibit no hepatotoxicity and cytotoxicity effects and stigmasterol (5) affords drug-likeness protocols. …”
Get full text

The importance of trunk motion in wearable based infant spontaneous movement analysis by María Marín-Palma, Ignacia Rojas-Sepulveda, Jessica Becerra-Caroca, José Carrasco-Plaza, Ramiro Zepeda, Pablo Ignacio Burgos

“…While the Prechtl method is effective in predicting motor risks, its reliance on the evaluator’s expertise limits its scalability, particularly in low-income areas. …”
Get full text

Climate Change Impact on Cereal Production in Northern Africa: A Comprehensive Modeling and Control Approach by Sabrina De Nardi, Claudio Carnevale, Sara Raccagni, Lucia Sangiorgi

“…Once validated, the models are integrated into a decision support system based on model predictive control aimed to balance global and regional climate objectives with economic considerations. …”
Get full text

Factors accounting for limited sexual reproduction in a long-lived unisexual plant species by Irene Bisang, Flavien Collart, Flavien Collart, Alain Vanderpoorten, Lars Hedenäs

“…Successful sexual reproduction, in terms of sporophyte occurrence, was confined to central Sweden. It was predicted by intermediate to increasing precipitation seasonality and intermediate temperature values.DiscussionDespite a high level of sex-expression, and no significant differences of niche preference between males and females, sporophyte occurrences were rare. …”
Get full text

A Systematic Review of the Prevalence and Diagnostic Workup of PIK3CA Mutations in HR+/HER2– Metastatic Breast Cancer by Elizabeth J. Anderson, Lea E. Mollon, Joni L. Dean, Terri L. Warholak, Ayal Aizer, Emma A. Platt, Derek H. Tang, Lisa E. Davis

“…., pairwise concordance, sensitivity, specificity, or predictive value) of respective mutation findings. A comprehensive search of PubMed/MEDLINE, EMBASE, Cochrane Central, and select conference abstracts (i.e., AACR, ASCO, SABCS, ECCO, and ESMO conferences between 2014 and 2017) identified 39 studies of patients with HR+, HER2– mBC. …”
Get full text

Studying attention to IPCC climate change maps with mobile eye-tracking. by Doga Gulhan, Bahador Bahrami, Ophelia Deroy

“…This study examines trends in visual attention to climate change predictions in world maps using mobile eye-tracking while participants engage with the visualisations. …”
Get full text

Regional modeling of surface solar radiation, aerosol, and cloud cover spatial variability and projections over northern France and Benelux by G. Chesnoiu, I. Chiapello, N. Ferlay, P. Nabat, M. Mallet, V. Riffault

“…Additional ALADIN climate simulations for 2050 and 2100 under Coupled Model Intercomparison Project phase 6 (CMIP6) Shared Socioeconomic Pathway (SSP) 1-1.9 predict a significant reduction in aerosol loads compared to 2005–2014, especially over Benelux, associated with future increases in clear-sky SSR but geographically limited all-sky SSR evolution. …”
Get full text

Using the diffusion of innovations theory to understand factors associated with COVID-19 vaccination among tobacco users. by Gail Carmen D'Souza, Jessica M Yingst, Nicolle M Krebs, Candace Bordner, Sophia I Allen, William A Calo, Andrea L Hobkirk, Jonathan Foulds

“…Additionally, the only reason for receiving the vaccine that significantly predicted early vaccine uptake (being an innovator or early adopter) was "to loosen restrictions on mask mandates and social/physical distancing" (p = 0.0180). …”
Get full text

Depression Detection and Diagnosis Based on Electroencephalogram (EEG) Analysis: A Systematic Review by Kholoud Elnaggar, Mostafa M. El-Gayar, Mohammed Elmogy

“…Finally, the review emphasizes improving the reliability and predictability of computational intelligence-based models to advance depression diagnosis. …”
Get full text

Automated skin lesion detection and prevalence estimation in Tamanend's bottlenose dolphins by Colin J. Murphy, Melissa A. Collier, Ann-Marie Jacoby, Eric M. Patterson, Megan M. Wallen, Janet Mann, Shweta Bansal

“…On the other hand, we find that individual-level analyses from the model predictions may be more sensitive to data quality, and thus, some individual scale questions may not be feasible to address if data quality is inconsistent. …”
Get full text

Insulin secretion, sensitivity, and clearance in normoglycemic Black and White adults with parental type 2 diabetes: association with incident dysglycemia by Samuel Dagogo-Jack, Jim Wan, Chimaroke Edeoga, Peace Asuzu

“…In Cox proportional hazards models, insulin secretion (HR 0.997 (95% CI 0.996 to 0.999), p=0.005), insulin sensitivity (HR 0.948 (95% CI 0.913 to 0.984), p=0.005), DI (HR 0.945 (95% CI 0.909 to 0.983), p=0.005) and basal insulin clearance (HR 1.030 (95% CI 1.005 to 1.056), p=0.018) significantly predicted incident dysglycemia.Conclusions Insulin sensitivity, secretion, and clearance differ significantly in normoglycemic African American versus European American offspring of parents with type 2 diabetes and are associated with the risk of incident dysglycemia.…”
Get full text