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20761
Efficiency of Disease and Disease Activity Diagnosis Models of Systemic Lupus Erythematosus Based on Protein Array Analysis
Published 2022-01-01“…Additionally, the three protein biomarkers contained in the disease activity distinguish model provided additional benefit to conventional biomarkers in predicting active lupus. Conclusions. The disease diagnosis model and disease activity diagnosis model that we developed based on protein array chip results showed high efficiency in differentiating patients with SLE from healthy controls and recognizing SLE patients with high disease activity, and they have also been validated. …”
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20762
The adaptation and evaluation of psychometric properties of the Lithuanian versions of the Faux Pas Recognition and Strange Stories tests
Published 2020-03-01“…One of the main subdomains of social cognitive functions, Theory of Mind (ToM), involves the ability to understand other people’s thoughts, intentions, emotions, and predict their behaviour. ToM deficit is common in many neurological and mental disorders. …”
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20763
Construction of an lncRNA-mediated ceRNA network to investigate the inflammatory regulatory mechanisms of ischemic stroke.
Published 2025-01-01“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses revealed that differentially expressed mRNAs (DEmRNAs) were significantly enriched in stroke-related pathways. Our analysis predicted four key lncRNAs, four miRNAs, and eleven crucial mRNAs involved in post-transcriptional regulation through competing endogenous RNA (ceRNA) mechanisms. …”
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20764
A comprehensive analysis to reveal the underlying molecular mechanisms of natural killer cell in thyroid carcinoma based on single-cell RNA sequencing data
Published 2025-01-01“…The mRNA-miRNA-lncRNA and transcription factors (TF) networks were constructed and the drug was predicted. Results The infiltration level of NK cell in THCA tissues was higher than that in paracancerous tissues. …”
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20765
Exploring Anharmonicity-induced high thermoelectric performance in α-In2X3 (X=S, Se) monolayers
Published 2025-01-01“…At room temperature, significantly low κl values of 1.90 W m−1 K−1 and 0.56 W m−1 K−1 are predicted for α-In2S3 and α-In2Se3, respectively, highlighting their potential for thermoelectric applications. …”
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20766
Investigation into the PSD characteristics of internally unstable soils susceptible to suffosion
Published 2025-01-01“…While extensive research has focused on establishing geometric criteria to assess the internal instability of soils prone to suffusion, current criteria fail to predict the occurrence of suffosion. To address this gap, this paper presents a comprehensive analysis by collecting a large amount of experimental data from existing literature, as well as conducting a series of suffusion/suffosion tests. …”
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20767
Single-cell transcriptomic profiling of heart reveals ANGPTL4 linking fibroblasts and angiogenesis in heart failure with preserved ejection fraction
Published 2025-02-01“…Immunohistochemistry and immunofluorescence staining then revealed the downregulation of vascular density and upregulation of ANGPTL4 expression in HFpEF hearts. Finally, we predicted ANGPTL4as a potential druggable target using DrugnomeAI. …”
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20768
The socioeconomic impact of kidney disease on African families: a scoping review
Published 2025-01-01“…Abstract Kidney disease is a non-communicable disease and a major global health burden, with increasing morbidity and mortality trends. It is predicted to become the fifth leading cause of disease by 2040. …”
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20769
An Open‐Label Phase II Trial of Pembrolizumab, an Immune Checkpoint Inhibitor Alone or in Combination With Oral Azacitidine as Second‐Line Therapy for Advanced Head and Neck Squamo...
Published 2025-01-01“…To examine the hypotheses on the predictive biomarkers of response to pembrolizumab, and the mechanisms of resistance. …”
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20770
Why have tobacco control policies stalled? Using genetic moderation to examine policy impacts.
Published 2012-01-01“…<h4>Methods</h4>A moderated regression analysis framework was used to test interactive effects between genotype and tobacco policy in predicting tobacco use. Cross sectional data of US adults from the National Health and Nutrition Examination Survey (NHANES) linked with genotype and geocodes were used to identify tobacco use phenotypes, state-level taxation rates, and variation in the nicotinic acetylcholine receptor (CHRNA6) genotype. …”
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20771
Preoperative Attention/Memory Problem Affects the Quality of Life of Parkinson’s Disease Patients after Deep Brain Stimulation: A Cohort Study
Published 2024-01-01“…Moreover, the preoperative PDQ-8 SI (β = 0.869, P<0.001) and the preoperative attention/memory subscore (β = −0.154, P=0.026) were predictive of the postsurgery improvement in quality of life (QoL). …”
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20772
Analysis of whole transcriptome reveals the immune response to porcine reproductive and respiratory syndrome virus infection and tylvalosin tartrate treatment in the porcine alveol...
Published 2025-01-01“…Based on our attention mechanism-improved graph convolutional network, 41.07% and 28.59% lncRNAs were predicted to be located in the nucleus and cytoplasm, respectively. …”
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20773
Studying agronomic characters in new millet accessions from the VIR collection at Yekaterinino Experiment Station of VIR
Published 2021-12-01“…Studying new accessions makes it possible to predict long-term development of the collection.Materials and methods. …”
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20774
Numerical Study on the Relationship between the Dominant Frequency of Blasting Vibration and the Development of Plastic Zone in Cylindrical Charge
Published 2022-01-01“…Many factors affect its dominant frequency, which makes analyzing, evaluating, and predicting it difficult. This study explored the factors influencing the dominant frequency of blasting vibrations in the case of a spherical charge. …”
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20775
LCANet: a model for analysis of students real-time sentiment by integrating attention mechanism and joint loss function
Published 2024-11-01“…Additionally, we conducted experiments using the model in real classroom scenarios, detecting and accurately predicting students’ classroom emotions in real time, which provides an important reference for improving teaching in smart teaching scenarios.…”
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20776
Identifying plasma exosome antigens as a potential diagnostic biomarker for tuberculosis disease
Published 2025-01-01“…Conclusion Levels of MPT64, Ag85A and CFP-10 were significantly up-regulated in plasma exosomes from TB patients and latent patients, and the AUC values of all three antigens predicting TB were higher than 0.9. This finding suggests that the three Mtb antigens in plasma exosomes were reliable diagnostic markers for TB.…”
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20777
The role of prosocial tendencies in the relationships between gratitude, perceived social support, and psychological well-being among Chinese university students: a structural equa...
Published 2025-01-01“…Multi-group SEM analysis was conducted to examine gender invariance.ResultsGratitude and perceived social support significantly predicted PWB, both directly and indirectly through prosocial tendencies. …”
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20778
Effect of manila palm (Veitchia merrillii Becc.) on rumen fermentation and microbial population in beef heifers
Published 2024-02-01“…In a such a manner that predicted ruminal CH4 production was decreased (P < 0.01) as MP was increased in diet. …”
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20779
Global stellarator coil optimization with quadratic constraints and objectives
Published 2025-01-01“…We demonstrate QUADCOIL’s effectiveness in coil topology control, minimizing non-convex penalties, and predicting filament coil complexity with three numerical examples.…”
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20780
NEIL3 Mediates Lung Cancer Progression and Modulates PI3K/AKT/mTOR Signaling: A Potential Therapeutic Target
Published 2022-01-01“…Inhibition of NEIL3 suppressed cyclinD1 and p-AKT protein levels; however, it had no effects on AKT levels, indicating that NEIL3 can partially activate the PI3K/AKT/mTOR signaling pathway. The predicted result of TIDE indicated that immunotherapeutic nonresponders had elevated NEIL3 levels. …”
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