Staphylococcus aureus carriage is associated with microbiome composition in the nares and oropharynx, not the hand, of monozygotic twins by Mark R. Dalman, W. Brian Simison, Danny Nielsen, Sabana Bhatta, Noor Ramahi, Clair Yee, Dipendra Thapaliya, Jhalka Kadariya, Shanice Cheatham, Hailee Olson, Tara C. Smith

“…With antibiotic-resistant strains causing 11,000 deaths yearly and ~2% of the population nasally colonized with methicillin-resistant S. aureus, a search for predictive markers and associative relationships between carriage have been long-sought goals. …”
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Machine learning assisted composition design of high-entropy Pb-free relaxors with giant energy-storage by Xingcheng Wang, Ji Zhang, Xingshuai Ma, Huajie Luo, Laijun Liu, Hui Liu, Jun Chen

“…A random forest regression model with key descriptors based on limited reported experimental data were developed to predict and screen the elements and chemical compositions of high-entropy systems. …”
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Computational assessment of measurable residual disease in acute myeloid leukemia using mixture models by Tim R. Mocking, Angèle Kelder, Tom Reuvekamp, Lok Lam Ngai, Philip Rutten, Patrycja Gradowska, Arjan A. van de Loosdrecht, Jacqueline Cloos, Costa Bachas

“…Using control samples (n = 18), we calculate a computational MRD percentage with high concordance to expert gating (Spearman’s rho = 0.823) and predict MRD status in a cohort of 35 AML follow-up measurements with high accuracy (97%). …”
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Genome-Wide Identification and Analysis of the Cytochrome B5 Protein Family in Chinese Cabbage (Brassica rapa L. ssp. Pekinensis) by Han Zheng, Xin Li, Lin Shi, Ying Jing, Qingqing Song, Yanan Chen, Lilong He, Fengde Wang, Jianwei Gao, Yuping Bi

“…Protein interaction analysis showed that 40 interaction patterns were predicted including two Sucrose Transporter 4 subfamily proteins (SUT 4) and Fatty Acid Hydroxylase 2 protein (FAH 2) can interact with most members of BrCB5s. …”
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Eating disorders in medical students: prevalence, risk factors, comparison with the general population by Raluca Motorga, Mihaela Ionescu, Florina Nechita, Daniela Micu, Iulia Băluțoiu, Maria Mădălina Dinu, Dan Nechita

“…ObjectivesThe main objectives were to investigate the prevalence of ED and associated risk factors among medical students in Romania, as well as to determine which variables may predict ED and to explore the differences between medical students and the general population.MethodsThe Eating Disorders Inventory questionnaire (EDI-3) was applied. …”
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Camel tick species distribution in Saudi Arabia and United Arab Emirates using MaxEnt modelling by Nighat Perveen, Sabir B. Muzaffar, Areej Jaradat, Olivier A. Sparagano, Arve L. Willingham, Ala Tabor

“…Several variables including land use/land cover (LULC) (53.1%), precipitation of coldest quarter (Bio19) (21.8%), elevation (20.6%), isothermality (Bio3) (1.9%), mean diurnal range [mean of monthly (max temp – min temp)] (Bio2) (1.8%), slope (0.5%), precipitation, seasonality (Bio15) (0.2%) influenced habitat suitability of ticks, predicting high tick density or abundance. Middle of the road scenario (ssp2-4.5) where CO2 levels remain similar to current levels, did not indicate a major change in the tick distributions. …”
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SIV infection induces alterations in gene expression and loss of interneurons in Rhesus Macaque frontal cortex during early systemic infection by Richard C. Crist, Samar N. Chehimi, Saurabh S. Divakaran, Michael J. Montague, Sébastien Tremblay, Noah Snyder-Mackler, Martin O. Bohlen, Kenneth L. Chiou, Trish M. Zintel, Cayo Biobank Research Unit, Michael L. Platt, Halvor Juul, Guido Silvestri, Matthew R. Hayes, Dennis L. Kolson, Benjamin C. Reiner

“…Differential expression identified alterations in cellular subtype gene expression that persisted over the 20-day time course and short-lived differences only detected at 10-days post-SIV infection. In silico predicted regulatory mechanisms and dysregulated neural signaling pathways are presented. …”
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Naringenin inhibits lipid accumulation by activating the AMPK pathway in vivo and vitro by Xiaoyu Cai, Songxue Wang, Huali Wang, Suwen Liu, Guishan Liu, Huibin Chen, Ji Kang, Hao Wang

“…The molecular mechanism of naringenin in the treatment of obesity were predicted by using network pharmacology. Real-time PCR analysis results showed that naringenin regulated the expression of lipid metabolism genes. …”
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Sensory alterations and immunological changes during the chronification of postsurgical pain: a study protocol for a prospective observational cohort study by Leo Koenderman, Niels Eijkelkamp, Frank J P M Huygen, Roel J H Custers, Marjelle E C van Driel, Nadine van Veenendaal, Lisette Margaretha Vernooij, L Timmerman, Diyar Delawi, M Rijsdijk

“…Cluster allocation, along with other preselected candidate predictors, will subsequently be used in a generalised mixed-effects model to predict CPSP with neuropathic features within 3 months after surgery as the primary outcome.Ethics and dissemination This study received approval from the Medical Ethics Committee NedMec (protocol NL77085.041.21), as well as from all participating centres. …”
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Predictors of HBsAg seroclearance in HBeAg-negative chronic hepatitis B patients treated with nucleotide analogs plus polyethylene glycol interferon by Yan Peng, Mingzhe Ma, Ting Liu, Wenmin He, Shutao Lin, Wa Zhong, Xiaohui Min

“…Through using univariate and multivariate analysis, we confirmed the predictive value of HBsAg, alanine aminotransferase (ALT) at week 24, and ALT change values from baseline to week 24. …”
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Effects of therapeutic alliance on patients with major depressive disorder: a literature review by Giovanni Videtta, Silvia Busilacchi, Giulia Bartoccioni, Luisa Cirella, Ylenia Barone, Giuseppe Delvecchio

“…Overall, the results suggest a bidirectional relationship between therapeutic alliance and symptom improvement, indicating that a stronger alliance often predicts better outcomes and symptom reduction can further enhance the alliance. …”
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Association Between Lung Parenchymal Attenuation in Computed Tomography and Airflow Limitation in Adults with Cystic Fibrosis by Lucía Esteban Baloira, Ester Zamarrón de Lucas, Carlos Carpio Segura, Macarena Lerín Baratas, María Fernández Velilla, María Isabel Torres Sánchez, Inmaculada Pinilla Fernández, Pablo Mariscal Aguilar, Rodolfo Álvarez-Sala Walther, Concepción Prados Sánchez

“…<b>Conclusions</b>: The measurements obtained from the automated quantification of lung parenchymal attenuation predicts airflow limitation in CF.…”
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Engagement in a web-based intervention for individuals who committed sexual offenses against children: observational study by Sonja Schröder, Safiye Tozdan, Peer Briken, Jürgen L. Müller, Peter Fromberger

“…The results of the present study indicate that (a) 81% of the participants logged into the web-based intervention within 8 weeks after login credentials were sent; (b) there was a trend toward lower treatment readiness and lower belief in their own technical prerequisites in individuals who did not login; (c) 15% of the participants completed all requested sessions within the first 5 weeks of participation, and the average participant logged in on 6 different days and completed two sessions; (d) the number of login days and completed sessions could be predicted by treatment readiness. We discuss these findings and their implications for the development and implementation of further web-based interventions in the forensic context. …”
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p53-loss induced prostatic epithelial cell plasticity and invasion is driven by a crosstalk with the tumor microenvironment by Darya Yanushko, Beatriz German Falcon, Rana El Bizri, Despoina Pervizou, Robin Dolgos, Céline Keime, Tao Ye, Christelle Thibault-Carpentier, Clementine Le Magnen, Sandrine Henri, Gilles Laverny, Daniel Metzger

“…The tumor suppressor genes PTEN and TP53 are frequently mutated in prostate cancer and are predictive of early metastatic dissemination and unfavorable patient outcomes. …”
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Harnessing the diversity of a lettuce wild relative to identify anthocyanin-related genes transcriptionally responsive to drought stress by Inés Medina-Lozano, Inés Medina-Lozano, Jérôme Grimplet, Jérôme Grimplet, Aurora Díaz, Aurora Díaz

“…Some wild variants had high or moderate predicted impacts on the respective protein function: a transcription factor that responds to abiotic stresses, a heat shock protein involved in stomatal closure, and a phospholipase participating in anthocyanin accumulation under abiotic stress. …”
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Future Extreme Climate Events Threaten Alpine and Subalpine Woody Plants in China by Yongru Wu, Jian Shen, David C. Deane, Haibin Yu, Fangyuan Yu, Xuerong Wang, Zheng Cao, Rong Yu, Fuan Xiao, Tiejun Wang, Zhifeng Wu

“…Here, we compared the predicted impacts of average climate with those including ECEs on 189 Rhododendron species in China for the historical period (1981–2010) and the future period (2071–2100) under two emissions scenarios (SSP2‐4.5 and SSP5‐8.5). …”
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Integrated analysis of dermatomyositis reveals heterogeneous immune infiltration and interstitial lung disease-associated endotype by Xinzhi Xu, Tianwen Qiu, Kexin Sun, Xue Han, Junxia Huang, Xiuyuan Wang, Jianchao Ge, Ji Yang

“…The identified biomarkers hold promise for determining an ILD-associated endotype and predicting clinical outcomes, thereby paving the way for timely management of DM and prevention of complications.…”
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Children’s Mental Health Visits to the Emergency Department: Factors Affecting Wait Times and Length of Stay by Amanda S. Newton, Sachin Rathee, Simran Grewal, Nadia Dow, Rhonda J. Rosychuk

“…ED type (pediatric ED: HR=1.71, 95% CI=1.18–2.46), triage level (CTAS 5: HR=2.00, 95% CI=1.15–3.48), number of consultations (HR=0.46, 95% CI=0.31–0.69), and number of laboratory investigations (HR=0.75, 95% CI=0.66–0.85) predicted LOS. Conclusions. Based on our results, quality improvement initiatives to reduce ED waits and LOS for pediatric mental health visits may consider monitoring triage processes and the availability, access, and/or time to receipt of specialty consultations.…”
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Valorization of Olive Pruning Residues through Bioconversion into Edible Mushroom Pleurotus ostreatus (Jacq. Ex Fr.) P. Kumm. (1871) of Improved Nutritional Value by Sami Abou Fayssal, Mohammed A. Alsanad, Zeina El Sebaaly, Ahmed I. H. Ismail, Youssef N. Sassine

“…Monounsaturated fatty acids increased in mushrooms of the substrates containing OLPR. A good predictive model of partial least square regression analysis showed different relationships of mushroom palmitic, oleic, linolenic, palmitoleic, and stearic acids with substrate composition. …”
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Baseline Triglyceride Level Affected the Efficacy of Vildagliptin in Treating Type 2 Diabetes: A Post Hoc Analysis of the VISION Study by Lingli Zhou, Xiaoling Cai, Yingying Luo, Fang Zhang, Linong Ji

“…Collectively, baseline TG was an independent predictive factor for the efficacy of a dipeptidyl peptidase-IV in treating type 2 diabetes during its initial use.…”
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