Large Multinodular Toxic Goiter: Is Surgery Always Necessary? by Roberto Negro, Gabriele Greco

“…This case demonstrates that 131I preceded by LAT represents a valid alternative strategy to surgery, even in the presence of two large coexistent hot nodules.…”
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Specificities of administrative dispute and constitutional complaint procedure by Manojlović Savo D.

“…The conclusion of the paper is that the administrative lawsuit, which historically precedes the constitutional complaint, shares significant "legal DNA" with it, making them distinct from other legal remedies and procedures. …”
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Acute phase responses in clinically healthy multiparous Holsteins with and without calcium dysregulation during the early postpartum period by J.A. Seminara, C.R. Seely, J.A.A. McArt

“…We hypothesized that dyscalcemic cows would experience more activated inflammation than eucalcemic cows and that inflammation would precede dyscalcemia diagnosis. Multiparous Holstein cows at 2 commercial dairy farms in central New York were enrolled from a parent study based on tCa at 4 DIM, at a 2:1 ratio of eucalcemic (tCa >2.3 mmol/L; n = 32) to dyscalcemic cows (tCa <2.2 mmol/L; n = 16). …”
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The Maddaloni/X-6 eruption stands out as one of the major events during the Late Pleistocene at Campi Flegrei by Giada Fernandez, Antonio Costa, Biagio Giaccio, Jacopo Natale, Danilo M. Palladino, Gianluca Sottili

“…However, the volcanic history preceding the VEI 7 Campanian Ignimbrite eruption (~40 ka) is still poorly constrained. …”
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Current End-of-Life Care Needs and Care Practices in Acute Care Hospitals by Amy J. Thurston, Donna M. Wilson, Jessica A. Hewitt

“…Only 13.8% had CPR performed at some point during this hospitalization and 8.8% had CPR immediately preceding death, with 87.5% having a DNR order and 30.8% providing an advance directive. …”
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Life cycle comparison of industrial-scale lithium-ion battery recycling and mining supply chains by Michael L. Machala, Xi Chen, Samantha P. Bunke, Gregory Forbes, Akarys Yegizbay, Jacques A. de Chalendar, Inês L. Azevedo, Sally Benson, William A. Tarpeh

“…Supply chain steps that precede refinement (material extraction and transport) contribute marginally to the environmental impacts of circular LIB supply chains (<4%), but are more significant in conventional supply chains (30%). …”
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Towards Transparent AI in Medicine: ECG-Based Arrhythmia Detection with Explainable Deep Learning by Oleksii Kovalchuk, Oleksandr Barmak, Pavlo Radiuk, Liliana Klymenko, Iurii Krak

“…This model processes a triad of cardio cycles—the preceding, current, and following cycles—to capture temporal dependencies and hidden features related to arrhythmias. …”
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Prophylactic use of recombinant ADAMTS-13 during pregnancy for congenital thrombotic thrombocytopenic purpura by Éloïse Colliou, Agnès Ribes, Clotilde Gaible, Mathilde Marlas, David Ribes, Isabelle Labadens, Paul Guerby, Stanislas Faguer

“…A full dose was given in the hours preceding the delivery and on day 3. No flare-up of cTTP occurred during the pregnancy, and rADAMTS-13 was tolerated well. …”
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The endocytic adaptor AP-2 maintains Purkinje cell function by balancing cerebellar parallel and climbing fiber synapses by Marianna Tolve, Janine Tutas, Ebru Özer-Yildiz, Ines Klein, Anne Petzold, Veronika J. Fritz, Melina Overhoff, Quinn Silverman, Ellie Koletsou, Filip Liebsch, Guenter Schwarz, Tatiana Korotkova, Silvana Valtcheva, Graziana Gatto, Natalia L. Kononenko

“…Synaptic dysfunction, marked by an overrepresentation of parallel fibers (PFs) over climbing fibers (CFs), precedes Purkinje cell loss. Mechanistically, AP-2 interacts with the PF-enriched protein GRID2IP, and its loss triggers GRID2IP degradation and glutamate δ2 receptor (GLURδ2) accumulation, leading to an excess of PFs while CFs are reduced. …”
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Stability evaluation of tunnels in steeply dipping layered rock mass using numerical models: a case study by Eleyas Assefa, Kidusyared Tilahun, Siraj Mulugeta Assefa, Nagessa Zerihun Jilo, Lysandros Pantelidis, Costas Sachpazis

“…Among widely used methods, the Convergence–Confinement Method (CCM), a prevalent two-dimensional (2D) approach, effectively captures the relaxation process preceding support installation. However, most studies focus on homogeneous or horizontally layered rock masses, often overlooking the influence of steeply dipping, and layered geological formations. …”
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A Rare Case of Paraneoplastic Syndrome Presented with Severe Gastroparesis due to Ganglional Loss by Konstantinos N. Argyriou, Martin Peters, Javaid Ishtiaq, Santosh Enaganti

“…Paraneoplastic syndromes are rare initial manifestations of a neoplastic disorder that may precede the actual detection of an overt cancer. These syndromes can generally involve any organic system of the human body with gastroparesis being the commonest manifestation of the paraneoplastic involvement of the neuronal bodies of the gastrointestinal tract in cancer patients. …”
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Principle of Virtual Work as Foundational Framework for Metamaterial Discovery and Rational Design by dell’Isola, Francesco, Misra, Anil

“…The needed novel research paradigm is one in which the formulation of theoretical concepts precede their experimental validation. In the absence of theoretical understanding, the design experiments and collection of experimental evidence will remain unavoidably circumscribed. …”
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Spatial Analysis and Socio-Environmental Determinants of Canine Visceral Leishmaniasis in an Urban Area in Northeastern Brazil by Natan Diego Alves de Freitas, Lucas José Macedo Freire, Suely Ruth Silva, Nilton Guedes do Nascimento, Pedro Cordeiro-Estrela

“…Dogs are considered the main urban reservoir of VL, whose infections precede cases in humans. In order to understand the socio-environmental determinants associated with canine visceral leishmaniasis (CVL), we conducted a spatial analysis of CVL cases in northeastern Brazil from 2013 to 2015, georeferencing 3288 domiciled dogs. …”
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Emergence of Exhausted B Cells in Asymptomatic HIV-1-Infected Patients Naïve for HAART is Related to Reduced Immune Surveillance by Manuela Fogli, Carlo Torti, Fabio Malacarne, Simona Fiorentini, Melania Albani, Ilaria Izzo, Cinzia Giagulli, Fabrizio Maggi, Giampiero Carosi, Arnaldo Caruso

“…These results provide new insights on B cell in HIV-1 infection and show that development of B cell abnormalities precedes CD4+ T cell decline.…”
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Anatomical Variations of the Circulus Arteriosus in Cadaveric Human Brains by S. A. Gunnal, M. S. Farooqui, R. N. Wabale

“…As it confirms high percentage of variations, all surgical interventions should be preceded by angiography. Awareness of these anatomical variations is important in neurovascular procedures.…”
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Rapidly Destructive Inflammatory Arthritis of the Hip by Jenny Shu, Ian Ross, Bret Wehrli, Richard W. McCalden, Lillian Barra

“…We report an original case of RDC as an initial presentation of seronegative rheumatoid arthritis (RA) in a 57-year-old Caucasian woman presenting with 6 months of progressive right groin pain and no preceding trauma or chronic steroid use. Over 5 months, she was unable to ambulate and plain films showed complete resorption of the right femoral head and erosion of the acetabulum. …”
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Mouse Reporter Strain for Noninvasive Bioluminescent Imaging of Cells that have Undergone Cre-Mediated Recombination by Michal Safran, William Y. Kim, Andrew L. Kung, James W. Horner, Ron A. DePinho, William G. Kaelin

“…Here we describe a mouse strain in which a luciferase (Luc) cDNA, preceded by a LoxP-stop-LoxP (L-S-L) cassette, was introduced into the ubiquitously expressed ROSA26 locus. …”
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Long-Term Follow-Up of the Telemonitoring Weight-Reduction Program “Active Body Control” by Gabriele Stumm, Alexandra Blaik, Siegfried Kropf, Sabine Westphal, Tanja Katrin Hantke, Claus Luley

“…The study presented here reports the results of a 1-year follow-up of 49 patients with the metabolic syndrome who had lost weight with the aid of the ABC program in the preceding year. The weight regain after the second year in patients not receiving any further care (“ABC discontinued” group; n=24) and the potential benefit of continuing with the ABC program with monthly counseling letters (“ABC continued” group; n=25) were investigated. …”
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Myristoylated Eepd1 Enhances Lipolysis and Thermogenesis through PKA Activation to Combat Obesity by Suzhen Chen, Yanping Wang, Qian Zhou, Qiqi Qian, Quanxin Jiang, Chuchu Liu, Yan Liu, Peihui Zhou, Jie Xiong, Yao Zhang, Ning Wang, Yang Emma Li, Limin Yin, Hongyuan Yang, Junli Liu

“…Abstract Middle-aged obesity, characterized by excessive fat accumulation and systemic energy imbalance, often precedes various health complications. Recent research has unveiled a surprising link between DNA damage response and energy metabolism. …”
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Mirative focalization: A case study of Mandarin lian-DP dou construction by Yue Xing

“…., the chunk formed by lian and the following nominal phrase, can represent two functional positions – in the clause-external Left Periphery (henceforth LP), and in the low IP area, because it occurs either preceding or following the alleged subject. In the present paper, however, I argue that a lian-DP, regardless of its linear position, undergoes successive-cyclic movement and, specifically, it first makes a stopover in SpecdouP for quantificational reasons before it takes a further step of mirative focus fronting targeting the LP. …”
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