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Synthesis and in vitro evaluation of spirobenzovesamicols as potential 11C-PET tracer alternatives to [18F]FEOBV for vesicular acetylcholine transporter (VAChT) imaging
Published 2025-02-01“…Abstract Background Through its central role in neurotransmission, the vesicular acetylcholine transporter (VAChT) is an increasingly valuable target for positron emission tomography (PET). VAChT ligands have been mostly derived from the vesamicol structure, but with limitations in available labelling methods and selectivity for VAChT against σ receptors being a common pitfall of such compounds, the development of selective VAChT tracers remains a challenge. …”
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Peri‐ictal yawning: A potential lateralizing sign in temporal lobe epilepsy
Published 2025-02-01“…Methods Among 236 consecutive TLE patients admitted for video‐EEG monitoring, we analyzed the clinical characteristics, along with scalp video‐EEG, magnetic resonance imaging (MRI), fluorodeoxyglucose‐positron emission tomography (FDG‐PET), Wada test, and stereo EEG (SEEG) in patients with PY. …”
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Advancements in noninvasive techniques for transplant rejection: from biomarker detection to molecular imaging
Published 2025-02-01“…Nuclear imaging modalities such as single photon emission computed tomography and positron emission tomography, enable dynamic visualization of immune responses within transplanted organs. …”
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Relationship between regional relative theta power and amyloid deposition in mild cognitive impairment: an exploratory study
Published 2025-02-01“…Advancements in amyloid positron emission tomography (PET) imaging have enhanced our understanding of the pathology of neurocognitive disorders, such as amyloid deposition. …”
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