A 10-Year Risk Assessment and Primary Prevention Study of Atherosclerotic Cardiovascular Disease Among Adult Patients in Saudi Arabia: A Cross-Sectional Study by Abdulhameed Alkhalaf, Qasem Aljabr, Khalid Al Mulla, Duaa Almubarak, Abdul Sattar Khan, Zainab Y. Al Jaziri, Ibrahim Albahrani

“…The ASCVD risk was calculated using the ACC/AHA Pooled Cohort Equations. Statistical analysis identified predictors of high ASCVD risk. …”
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Real‐world efficacy of transfusion with liberal or restrictive strategy in traumatic brain injury by Liang‐Wen Cui, Nian Liu, Chao Yu, Ming Fang, Rui Huang, Cheng Zhang, Min Shao

“…The standardized, weighted pooled logistic regression with 500 bootstrap resampling was used to estimate the cumulative risk difference and 95% confidence interval (CI). …”
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Co-occurring factors associated with suicidal ideation among individuals with parole involvement: A classification and regression tree analysis by Leah MCCOY, Javier F. BOYAS, Sung Seek MOON, Michael A. ROBINSON, Onick LEWIS, Amy E. COX

“…This study explored specific physical health, mental health, and substance use predictors contributing to suicidal ideation among individuals with parole involvement. Methods: Pooled data from the National Survey on Drug Use and Health were analyzed through a CART analysis to uncover co-occurring interactions associated with suicidal ideation among a national sample of individuals with parole involvement (N=1,725). …”
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The Effects of Hyperacute Serum on the Elements of the Human Subchondral Bone Marrow Niche by Melinda Simon, Bálint Major, Gabriella Vácz, Olga Kuten, István Hornyák, Adél Hinsenkamp, Dorottya Kardos, Marcell Bagó, Domonkos Cseh, Adrienn Sárközi, Denes Horvathy, Stefan Nehrer, Zsombor Lacza

“…Additionally, blood derivatives are commonly used in musculoskeletal diseases like osteoarthritis (OA) or osteonecrosis as “proliferative agents” for the topical MSC pool. Hyperacute serum (HAS), a new serum derivative, has been designed to approximate the natural coagulation cascade with a single-step, additive-free preparation method. …”
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Rebar Recognition Using Multi-Hyperbolic Attention in Faster R-CNN by Chuan Li, Nianbiao Cai, Tong Pu, Xi Yang, Hao Liu, Lulu Wang

“…Before the Region Proposal Network (RPN) and region of interest (ROI) pooling stages in Faster R-CNN, this study integrates a hyperbolic attention (HAT) module. …”
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Metabolic Modulation and Potential Biomarkers of the Prognosis Identification for Severe Aortic Stenosis after TAVR by a Metabolomics Study by Yanbiao Liao, Chang Liu, Tianyuan Xiong, Mingyue Zhao, Wen Zheng, Yuan Feng, Yijian Li, Yuanweixiang Ou, Zhengang Zhao, Yong Peng, Jiafu Wei, Qiao Li, Wei Meng, Xiaojing Liu, Mao Chen

“…The early (within 7 days after TAVR) changed metabolites in the peripheral vein were involved in purine metabolism, primary bile acid biosynthesis, glycerolipid metabolism, amino sugar and nucleotide sugar metabolism, one carbon pool by folate and alanine, and the aspartate and glutamate metabolism pathway. …”
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Accelerated development of multi-component alloys in discrete design space using Bayesian multi-objective optimisation by Osman Mamun, Markus Bause, Bhuiyan Shameem Mahmood Ebna Hai

“…Finally, we demonstrate the effectiveness of a pool-based AL protocol in expediting the discovery process by executing multiple computational and experimental campaigns in each iteration. …”
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A Rewired NADPH-Dependent Redox Shuttle for Testing Peroxisomal Compartmentalization of Synthetic Metabolic Pathways in <i>Komagataella phaffii</i> by Albert Fina, Sílvia Àvila-Cabré, Enrique Vázquez-Pereira, Joan Albiol, Pau Ferrer

“…Thereafter, we used compartmentalized 3-HP production as a reporter system to showcase the impact of different strategies aimed at enhancing the peroxisomal NADPH pool. Co-overexpression of genes encoding a NADPH-dependent redox shuttle from <i>Saccharomyces cerevisiae</i> (<i>IDP2</i>/<i>IDP3</i>) significantly increased 3-HP yields across all substrates, whereas peroxisomal targeting of the <i>S. cerevisiae</i> NADH kinase Pos5 failed to improve 3-HP production. …”
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Thresholds of handgrip strength for all-cause mortality in patients with chronic kidney disease: a secondary systematic review with dose-response meta-analysis by Hao Chen, Fan Zhang, Liuyan Huang, Yan Bai, Yifei Zhong, Yi Li

“…We utilized estimates of handgrip strength categories using robust-error meta-regression (REMR), pooled study-specific estimates, and established dose-response relationships. …”
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Resiquimod induces a mixed Th1 and Th2 response via STAT1 and STAT3 signalling in chickens by Deepthi Kappala, Saravanan Ramakrishnan, Patel Nikunjkumar Prakashbhai, Abinaya Kaliappan, Prasad Thomas, Jörg Linde, Mithilesh Singh, Sohini Dey, Madhan Mohan Chellappa

“…The current research investigates the molecular mechanisms underlying these immune responses in chickens. Pooled splenocytes harvested from chickens (n = 2/group) at 24 h post R-848 treatment were subjected to RNA sequencing and significant differentially expressed genes (DEGs) were identified compared to controls. …”
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Concerning the issue of early diagnostics of low tannin content in faba bean seeds (<i>Vicia faba</i> L.) by S. M. Mamedova, V. S. Popov, A. E. Solovyeva, I. N. Perchuk, L. L. Malyshev, M. A. Vishnyakova

“…The existence of low-tannin or zero-tannin forms in the faba bean gene pool allows breeders to promote this trait. The aim of this work was to carry out biochemical validation of a known morphological marker of low tannin content and identify relationships of some phenotypic traits characterized by accumulation of phenolic compounds (tannins and anthocyanins) with their concentration for use as additional morphological markers of the low content of these antinutrients in bean seeds.Materials and methods. …”
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Phenotypic divergence across populations does not affect habitat selection in an Amazonian poison frog by Martin Mayer, Lia Schlippe Justicia, Bibiana Rojas

“…Frogs selected for proximity to tree falls, dead woody material, presence of water pools, and avoided areas with extensive ground vegetation and little canopy cover. …”
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Investigations of Long-Acting Formulations in Children, Adolescents, and Pregnant Women: A Systematic Review by Lynn Bertagnolli, Zhengyi Deng, Melissa Davy-Rothwell, Elaine J. Abrams, Charles Flexner, Ethel D. Weld

“…Therapeutics for only a small pool of indications were examined in these studies, with 72% of the studies investigating hormonal contraception or other types of hormonal treatments. …”
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A breeding method for Ogura CMS restorer line independent of restorer source in Brassica napus by Xuesong Wang, Xingyu Liang, Rui Wang, Yuan Gao, Yun Li, Haoran Shi, Wanzhuo Gong, Saira Saleem, Qiong Zou, Lanrong Tao, Zeming Kang, Jin Yang, Qin Yu, Qiaobo Wu, Hailan Liu, Shaohong Fu

“…To further investigate and locate the restorer gene, the BSA method was employed to construct extreme mixed pools. As a result, the restorer gene was mapped to three positions: A09 chromosome 10.99–17.20 Mb, C03 chromosome 5.07–5.34 Mb, and C09 chromosome 18.78–36.60 Mb. …”
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Rituximab-associated adverse events in nephrotic syndrome: A systematic review and meta-analysis by Zixian Yu, Meijin Huang, Yunlong Qin, Xiayin Li, Yueru Zhao, Yuwei Wang, Yumeng Zhang, Anjing Wang, Mei Han, Jin Zhao, Shiren Sun

“…RTX significantly reduced the risk of total AEs (OR = 0.32, 95 % CI [0.13, 0.78]) compared to the non-RTX group in retrospective studies but was not in RCTs. The pooled rate of infusion reactions was 32 % (95 % CI = [19 %, 45 %]) in RCTs and 8 % (95 % CI = [3 %, 13 %]) in retrospective studies. …”
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Synergistic toughening of welds through adding SiC nanoparticles and modulating oscillating laser by Mingjun Zhang, Rui Wang, Xiaobing Pang, Jian Zhang, Cong Mao, Bo Cheng, Longzhou Dai, Heqing Li, Jing Guo, Zhuming Bi

“…However, SiC nanoparticles have high-level of surface energy, the physical properties of SiC nanoparticles are significantly different from Mg alloy, and these tend to cause the instability of a molten pool and a keyhole in laser-welding. This study proposed to modulate the power of an oscillating laser and control the temporal and spatial distribution of laser energy to strengthen welds when SiC nanoparticles are applied to join AZ31B Mg alloy. …”
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Association of Methylenetetrahydrofolate Reductase C677T Gene Polymorphisms with Mild Cognitive Impairment Susceptibility: A Systematic Review and Meta-Analysis by Jiahui Sun, Xuefan Jiang, Ming Zhao, Lina Ma, Hui Pei, Nanyang Liu, Hao Li

“…We used fixed or random effects to examine the association between MTHFR C677T (rs1801133) gene variants and MCI susceptibility. Forest plots of pooled odds ratios (ORs) and 95% confidence intervals (CIs) were generated. …”
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LINE-1 methylation status and survival outcomes in colorectal cancer patients: A systematic review and meta-analysis by Akbar Bagheri, Tohid Jafari-Koshki, Leila Alizadeh, Mortaza Raeisi, Yaghoub Moaddab, Abbas Karimi

“…A total of 19 studies comprising 8169 CRC patients were included. The pooled analysis showed no significant association between LINE-1 hypomethylation and OS in the overall population (HR = 1.70, 95 % CI: 0.97–2.96). …”
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Association of the Interleukin-10-592C/A Polymorphism and Cervical Cancer Risk: A Meta-Analysis by Brehima Diakite, Yaya Kassogue, Mamoudou Maiga, Guimogo Dolo, Oumar Kassogue, Jonah Musa, Imran Morhason-Bello, Ban Traore, Cheick Bougadari Traore, Bakarou Kamate, Aissata Coulibaly, Sekou Bah, Sellama Nadifi, Robert Murphy, Jane L. Holl, Lifang Hou

“…Fixed-effects or random-effects models were performed with pooled odds ratios (ORs). Heterogeneity and bias tests were performed by the inconsistency test and funnel plot, respectively. …”
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Diagnosis of Autism Spectrum Disorder (ASD) by Dynamic Functional Connectivity Using GNN-LSTM by Jun Tang, Jie Chen, Miaojun Hu, Yao Hu, Zixi Zhang, Liuming Xiao

“…Further, a dynamic graph pooling method is proposed to extract the final node representations from the dynamic graph representations for classification tasks. …”
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