Association between parity and gravidity & hypertension and blood pressure: protocol for a systematic review and meta-analysis by Sofia B Ahmed, Sonia Butalia, Magali Robert, Tyrone G Harrison, Sandra M Dumanski, Nabilah Gulamhusein, Badal S B Pattar, Jane A Schulz

“…If there are sufficient data, they will be summarised using random effects meta-analysis to estimate the pooled risk ratio or odds ratio of hypertension. Stratified and subgroup analyses will be used to explore potential sources of heterogeneity.PROSPERO registration number CRD42024560535.…”
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Development and Validation of a Bedside Scale for Assessing Upper Limb Function Following Stroke: A Methodological Study. [version 1; peer review: 2 approved] by Sampath Kumar Amaravadi, Vijayakumar Palaniswamy, Akshatha Nayak, Dhaval Pawani, Prasanna Mithra, Ashish John Prabhakar, Abraham M. Joshua

“…Subsequently, an item pool of 18 UL movements was developed. A mini-Delphi method was employed to verify content validity. …”
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ID-UNet: A densely connected UNet architecture for infrared small target segmentation by Diankun Chen, Feiwei Qin, Ruiquan Ge, Yong Peng, Changmiao Wang

“…Existing CNN-based approaches face challenges in effectively and efficiently managing diverse scales of small infrared objects within intricate scenes, primarily as a result of the aggregation effect induced by pooling layers. As a consequence, crucial deep targets may be lost. …”
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The nature of self-medication in Uganda: a systematic review and meta-analysis by Danladi Makeri, Priscilla Peter Dilli, Theophilus Pius, Naheem Adekilekun Tijani, Abdullateef Afolabi Opeyemi, Kadai Alhaji Lawan, Shango Patience Emmanuel Jakheng, Reagan Muhwezi, Ambrose Shabohurira, Ibe Michael Usman, Ezera Agwu

“…Our analysis revealed a 55.63% (95%CI [40.40; 70.66] pooled prevalence of self-medication in Uganda. Antibiotics are the commonly self-medicated drugs and ease of access to medications, perceived cost effectiveness, long hospital waiting time, home storage of drugs (leftovers), and perceptions of minor illnesses were key contributors to self-medication behaviour. …”
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Immunologic investigations into transgene directed immune-mediated myositis following delandistrogene moxeparvovec gene therapy by Rachael A. Potter, Ida H. Moeller, Sohrab Khan, Hélène Haegel, Andreas Hollenstein, Guido Steiner, Christoph Wandel, Alexander P. Murphy, Damon R. Asher, Emanuel Palatinsky, Danielle A. Griffin, Stefanie Mason, Susan T. Iannaccone, Craig M. Zaidman, Louise R. Rodino-Klapac

“…An interferon-gamma ELISpot assay was used to detect T cell responses to delandistrogene moxeparvovec micro-dystrophin peptide pools. ELISpot analysis suggested that IMM resulted from T cell-mediated responses directed against specific micro-dystrophin peptides corresponding to exons 8 and 9 (Case 1) and exon 8 (Case 2) of the DMD gene. …”
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Efficacy and Acceptability of Orthokeratology for Slowing Myopic Progression in Children: A Systematic Review and Meta-Analysis by Daizong Wen, Jinhai Huang, Hao Chen, Fangjun Bao, Giacomo Savini, Antonio Calossi, Haisi Chen, Xuexi Li, Qinmei Wang

“…At 2-year follow-up, a statistically significant difference was observed in axial length change between the orthokeratology and control groups, with a weighted mean difference (WMD) of −0.25 mm (95% CI, −0.30 to −0.21). The pooled myopic control rate declined with time, with 55, 51, 51, and 41% obtained after 6, 12, 18, and 24 months of treatment, respectively. …”
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Effect of metformin on the clinical outcomes of stroke in patients with diabetes: a systematic review and meta-analysis by Jianming Zhu, Jun Wen, Zhihua Huang, Jianyi Liu, Fuqun Luo, Yizhi Guo, Yandeng Li

“…In this study, we aim to scrutinise the effects of metformin on the clinical outcomes of stroke in diabetic patients.Design This study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.Data sources PubMed, Embase and Web of Science databases were searched between their inception and 5 December 2023.Eligibility criteria for selecting studies Studies investigating the effect of metformin on the clinical outcomes of stroke in patients with diabetes were included.Data extraction and synthesis The effect of metformin on the clinical outcomes of stroke in patients with diabetes was identified using combined ORs and 95% CIs.Results A total of 11 studies involving 18 525 participants were included in this review. Pooled analysis has demonstrated that prestroke metformin use could reduce the probability of poor course after stroke by 34% in diabetes mellitus (DM) patients (OR=0.66, 95% CI: 0.61 to 0.72) and reduce the probability of death by 43% (OR=0.57, 95% CI: 0.51 to 0.64).Conclusions Prestroke metformin use is beneficial for the improvement of clinical outcomes in patients who had a stroke with DM, although the potential bias should be carefully considered.PROSPERO registration number CRD42024496056.…”
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Association between NSAIDs and Clostridium difficile-Associated Diarrhea: A Systematic Review and Meta-Analysis by Nitipong Permpalung, Sikarin Upala, Anawin Sanguankeo, Suthanya Sornprom

“…The nine studies from which data were extracted involved over 39,000 subjects. The pooled odds ratio for history of NSAID use in participants with CDAD compared with controls was 1.41 (95% CI 1.06–1.87; p<0.01), indicating a significant increased odds of CDAD among patients exposed to NSAIDs. …”
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DPP-4 Inhibitors as Treatments for Type 1 Diabetes Mellitus: A Systematic Review and Meta-Analysis by Qixian Wang, Min Long, Hua Qu, Rufei Shen, Rui Zhang, Jing Xu, Xin Xiong, Hui Wang, Hongting Zheng

“…From this meta-analysis, pooled data from 5 randomized controlled trials revealed that the additional use of DPP-4 inhibitors resulted in a greater decrease in glycated hemoglobin A1c (HbA1c) levels (0.07%, 95% CI (−0.37%–0.23%)) than insulin monotherapy, although the decrease was not significant. …”
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Novel carbon dots with dual Modulatory effects on the bone marrow and spleen as a potential therapeutic candidate for treating spinal cord injury by Junjin Li, Hongda Wang, Yuanquan Li, Chunzhen Wang, Haiwen Feng, Yilin Pang, Jie Ren, Chuanhao Li, Erke Gao, Dejing Zhang, Dunxu Hu, Pengtian Zhao, Han Ding, Baoyou Fan, Tao Zhang, Xiaomeng Song, Zhijian Wei, Guangzhi Ning, Yong-Qiang Li, Shiqing Feng

“…Simultaneously, bone marrow hematopoietic stem cells (HSCs) and splenic leukocytes rapidly mobilize to replenish the depleted peripheral blood leukocyte pool. However, current treatments for spinal cord injuries overlook interventions targeting peripheral immune organs and tissues, highlighting the need to develop novel drugs capable of effectively regulating peripheral immunity and treating spinal cord injuries. …”
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The quality of service assessment of eMBB and mMTC traffic in a clustered 5G ecosystem of a smart factory by Viacheslav Kovtun, Oksana Kovtun, Krzysztof Grochla, Oleh Yasniy

“…The article proposes two new multi-parameter scenarios for allocating the entire channel pool between different types of requests (mMTC, eMBB) for the model of an integrated open 5G cluster. …”
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An Investigation Into a Lightweight Safety Helmet Detection Approach Utilizing the MSS-YOLO Framework by Bing Zeng, Zhanpeng Liao, Yu Zhou, Dilin He, Zhihao Zhou, Kexin Yi, Yuwen Li, Xiaopin Yang, Yunmin Xie

“…Subsequently, an improved lightweight spatial pyramid pooling module, simSPPF-N(simplified SPPF-NAM), is appended to the backbone network, facilitating a more effective amalgamation of local and global features. …”
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Effectiveness of midwife/nurse-led non-invasive uterine massage in preventing postpartum haemorrhage: a quantitative systematic review protocol by Puangpaka Kongvattananon, Boonsurb Sosome, Sopen Chunuan, Treechada Punsomreung, Panida Varachanonth, Patraporn Bhatarasakoon

“…Two independent reviewers will conduct the review, with data extraction and quality evaluation. Studies will be pooled in a statistical meta-analysis using JBI System for the Unified Management, Assessment and Review of Information or other software where possible.Ethics and dissemination This systematic review does not require formal ethical approval because all data will be analysed anonymously. …”
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Signal Game Analysis on the Effectiveness of Coal Mine Safety Supervision Based on the Affective Events Theory by Xue Yang, Yang Tian, Kai Feng, Juan Yang, Shu-hui Zhang, Shengnan Wang

“…Under the separating equilibrium state, the emotional supervision system faces “the paradox of almost totally safe systems” and will be broken; the emotion-driven miners disguising any negative emotions will be permitted to work in the coal mine, creating a safety risk. Under the pooling equilibrium state, strong economic constraints, such as setting suitable safety risk deposits, may achieve effective emotional supervision of the miners, reducing the safety risk. …”
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High throughput single cell metagenomic sequencing with semi-permeable capsules: unraveling microbial diversity at the single-cell level in sewage and fecal microbiomes by Meilee Ling, Judit Szarvas, Vaida Kurmauskaitė, Vaidotas Kiseliovas, Rapolas Žilionis, Rapolas Žilionis, Baptiste Avot, Baptiste Avot, Patrick Munk, Frank M. Aarestrup

“…Our method involves extracting and amplifying single bacterial DNA within individual SPCs, followed by combinatorial split-and-pool single-amplified genome (SAG) barcoding and short-read sequencing. …”
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Cost Estimation and Efficiency Analysis of Korean CANDU Spent Fuel Disposal Alternatives in Consideration of Future Price Volatility by Sungsig Bang, Yanghon Chung, Dongphil Chun, Chulhong Kwon, Sungjun Hong

“…In Korea, spent fuel is temporarily stored in spent fuel pools at nuclear reactor sites and it is predicted to become saturated between 2020 and 2024. …”
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Psychological Therapies in Patients with Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials by Osama Altayar, Varun Sharma, Larry J. Prokop, Amit Sood, Mohammad Hassan Murad

“…We used the random-effect model to pool standardized mean difference (SMD) and 95% confidence interval (CI) across trials. …”
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Plant Growth-Promoting and Herbicidal Bacteria as Potential Bio-Based Solutions for Agriculture in Desertic Regions by Patricio Muñoz-Torres, Wilson Huanca-Mamani, Steffany Cárdenas-Ninasivincha, Yola Aguilar, Antonio Quezada, Franco Bugueño

“…Notable locations include Jurasi Hot Springs, Polloquere Hot Springs, and Amuyo Lagoons, featuring open pools fed by thermal mountain springs. These geothermal sites harbor bacteria with plant growth-promoting activities, particularly interesting to the strains J19, TP22, A20, and A3. …”
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Fire Model Test on Temperature Field in the Rescue Station of an Extralong Railway Tunnel by Yanhua Zeng, Kelin Liu, Yong Fang, Xianfu Zhang, Yun Bai

“…This paper performs a similarity simulation model test at 1 : 10 geometric scale to investigate the temperature field in a rescue station. A gasoline pool fire was used as the fire source. The influences of the fire source position and ventilation condition on the temperature field were studied. …”
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Low-Resolution Target Detection with High-Frequency Information Preservation by Feng Zhang, Hongyang Bai, Wenlong Yin, Ze Li, Hailong Ma, Lei Chen

“…This challenge can be further exasperated by typical downsampling operations (e.g., pooling, stride) of existing deep networks (e.g., CNNs). …”
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