Optimization of treatment and prevention of recurrences of bacterial vaginosis in postmenopausal women by S.O. Ostafiichuk, N.V. Drogomyretska, O.M. Kusa, O.V. Neiko, I.V. Levitsky, N.M. Kinash

“…In the women of the first group, the risk of recurrence of the laboratory criteria of BV increases after 3 months: an increase in the pH of the vaginal contents by 1.2 times (p<0.05), the appearance of a positive aminotest in 38.1% of patients, the presence of Gardnerella vaginalis in 26.2% women with a pathological number of 104-105 CFU/ml, regression of the pool of lactobacilli with worsening of the situation and the appearance of clinical manifestations of the disease after 6 months. …”
Get full text

Adverse Effects of Intraparenchymal and Peritumoral Application of Isosulfan Blue Dye in Sentinel Lymph Node Mapping in Breast Cancer: A Systematic Review and Meta-Analysis by Joshua Agilinko, Aditya Borakati, Andrel Yoong, Ponnuthurai Pratheepan, Suzette Samlalsingh

“…A total of 19,183 patients were identified from eight studies. The pooled total adverse event rate after isosulfan administration was 11.65 events per 1,000 patients [95% confidence interval (CI) 7.44–18.19]. …”
Get full text

Neuropsychiatric manifestations following chimeric antigen receptor T cell therapy for cancer: a systematic review of clinical outcomes and management strategies by Max Topp, Michael Hudecek, Hermann Einsele, Imad Maatouk, Leo Rasche, Johannes Duell, Anna Fleischer, Sophia Kurth, Patrick-Pascal Strunz, Julia Mersi, Carmen Sanges

“…The synthesis of findings was conducted via a narrative approach, consolidating the diverse array of data into a coherent framework.Results From an initial pool of 2,276 citations, 546 studies met the inclusion criteria, exhibiting a rich tapestry of heterogeneity in terms of study characteristics and patient samples. …”
Get full text

Transition to home after very preterm birth: improving outcomes of children and their families—a systematic review protocol by Beatrice Latal, Ulrike Held, Ursula Kiechl-Kohlendorfer, Sandra Siegfried, Vivienne Engel, Valentina Mauron-Papadimitriou, Lea Bührer, Laura Ebner, Lena Keller, Martina Gosteli

“…Subsequently, it will show the individual effect of these interventions and pool effect sizes if possible. The most promising interventions will then be combined and used as the basis of a subsequent randomised controlled trial of a new transition-to-home intervention. …”
Get full text

Survival status of women with cervical cancer in Sub-Saharan Africa: a systematic review and meta-analysis, 2024 by Tadele Emagneneh, Chalie Mulugeta, Betelhem Ejigu, Abebaw Alamrew, Aynalem Yetwale Hiwot, Sefineh Fenta Feleke

“…Based on the random-effects model, the overall pooled 1-year survival was 65.0% [95% confidence interval (CI), 52–78] with I² = 99.31 and p-value &lt; 0.001. …”
Get full text

Acquisition of innate B cell properties and generation of autoreactive IgA antibodies by follicular B cells during homeostatic proliferation by Laura Kampe, Laura Kampe, Christian Melcher, Christian Melcher, Katrin Westphal, Katrin Westphal, Korbinian Brand, Niko Föger, Niko Föger, Kyeong-Hee Lee, Kyeong-Hee Lee

“…The physiologic process of homeostatic proliferation serves to restore the pool of peripheral lymphocytes in response to lymphopenia. …”
Get full text

Effectiveness and safety of percutaneous endoscopic debridement and drainage for spinal infections: a systematic review and meta-analysis by Guozhong Zhou, Xiaorong Liu, Zhi Liang, Xuesong Chen, Chao Song

“…We assessed study quality using a modified Newcastle–Ottawa Scale and conducted a random-effects meta-analysis to calculate pooled results. Results Overall, 36 studies involving 925 patients were included. …”
Get full text

Predictive value of circulating fibroblast growth factor-23 and Klotho on protein-energy wasting in patients undergoing hemodialysis by Xiaoling Zhou, Yang Luo, Yidan Guo, Meng Jia, Chunxia Zhang, Zhihua Shi, Ye Du

“…PEW was significant positively correlated with FGF-23 (r = 0.403, p &lt; 0.001), age (r = 0.225, p = 0.006), C-reactive protein (r = 0.236, p = 0.004), intact parathyroid hormone (r = 0.237, p = 0.004), and single-pool Kt/V (r = 0.170, p = 0.040), while it was negatively correlated with Klotho (r = −0.361, p &lt; 0.001), hemoglobin (r = −0.215, p = 0.009), and serum creatinine (r = −0.278, p = 0.001). …”
Get full text

Diagnostic features, management and prognosis of type 2 myocardial infarction compared to type 1 myocardial infarction: a systematic review and meta-analysis by Kyle White, Ian Scott, Mansey Kinarivala

“…Importance Distinguishing type 2 (T2MI) from type 1 myocardial infarction (T1MI) in clinical practice can be difficult, and the management and prognosis for T2MI remain uncertain.Objective To compare precipitating factors, risk factors, investigations, management and outcomes for T2MI and T1MI.Data sources Medline and Embase databases as well as reference list of recent articles were searched January 2009 to December 2020 for term ‘type 2 myocardial infarction’.Study selection Studies were included if they used a universal definition of MI and reported quantitative data on at least one variable of interest.Data extraction and synthesis Data were pooled using random-effect meta-analysis. Risk of bias was assessed using Newcastle-Ottawa quality assessment tool. …”
Get full text

Epidemiology of Methicillin-resistant Staphylococcus aureus Colonization in Neonates within Neonatal Intensive Care Units: A Systematic Review and Meta-analysis by Seraphine Nkie Esemu, Arnol Bowo-Ngandji, Roland Ndip Ndip, Jane-Francis Tatah Kihla Akoachere, Nene Kaah Keneh, Jean Thierry Ebogo-Belobo, Cyprien Kengne-Ndé, Donatien Serge Mbaga, Nicholas Tendongfor, Hortense Kamga Gonsu, Jean Paul Assam Assam, Lucy Mande Ndip

“…Statistical analysis included a random-effects model to compute pooled proportions, stratification by geographical location, evaluation of heterogeneity, and examination of publication bias. …”
Get full text

Population Pharmacokinetics of Pegcetacoplan in Patients with Geographic Atrophy or Neovascular Age-related Macular Degeneration by Ryan L. Crass, PharmD, Komal Prem, MD, Francois Gauderault, PhD, Ramiro Ribeiro, MD, PhD, Caroline R. Baumal, MD, Brandon Smith, PhD, Daniel Epling, PhD, Sunny Chapel, PhD

“…Methods: Serum concentration data were pooled from 4 clinical studies. Pegcetacoplan dosing included single intravitreal injections of 4, 10, and 20 mg and multiple intravitreal injections of 15 mg monthly or every other month. …”
Get full text

Effect of Aerobic Exercise on Blood Glucose Among Those with Prediabetes: A Systematic Review and Meta-Analysis by Tianyi Jiang, Zichen Ye, Qu Lu, Peixia Cheng, Qi Gao

“…Subgroup analysis showed that pooled effect size for FBG, 2hPG, and HbA1c was greater in the subgroup subjected to ≥48 weeks of intervention compared to the subgroup subjected to ≤24 weeks of intervention, although only the difference in FBG was significant (<i>p</i> < 0.05). …”
Get full text

Association of Depression/Anxiety Symptoms with Neck Pain: A Systematic Review and Meta-Analysis of Literature in China by Fushui Liu, Ting Fang, Fanyuan Zhou, Meimei Zhao, Mei Chen, Jianyu You, Yuli Jin, Jinmei Xie, Zhongyong Liu

“…Compared with healthy control participants, the findings indicated that depression/anxiety symptoms were more common or severe in NP patients (respectively, SMD = 0.89; 95% CI = (0.58, 1.20); P<0.01 and SMD = 0.92; 95% CI = (0.65, 1.20); and P<0.01), results from the pooled data demonstrated no statistical significance between depression/anxiety symptoms and gender in NP patients (resp., SMD = 0.16; 95% CI = (−0.18, 0.51); P=0.35 and SMD = −0.08; 95% CI = (−0.42, 0.27); and P=0.67), and the combined data of the incidence of depression or anxiety symptoms revealed significant difference between NP patients and healthy persons (resp., RR = 4.81; 95% CI = (3.30, 7.01); P<0.01 and RR = 3.29; 95% CI = (2.16, 5.00); and P<0.01). …”
Get full text

Long-acting family planning uptake and associated factors among women in the reproductive age group in East Africa: multilevel analysis by Ermias Bekele Enyew, Abiyu Abadi Tareke, Habtamu Setegn Ngusie, Mulugeta Desalegn Kasaye, Shimels Derso Kebede, Mahider Shimelis Feyisa

“…A community-based cross-sectional study was conducted on the most recent Demographic and Health Surveys in 12 East African countries. The pooled prevalence of long-acting contraceptive uptake with a 95% confidence interval (CI) was reported and presented in a forest plot for East African countries using STATA version 14.1. …”
Get full text

The associations between sedentary behavior and neck pain: a systematic review and meta-analysis by Yunchen Meng, Yaqi Xue, Sanjun Yang, Fang Wu, Yanyu Dong

“…Due to significant heterogeneity among the studies, a random-effects model was employed for the meta-analysis to obtain pooled estimates. Results A total of 25 studies with 43,184 participants met the eligibility criteria. …”
Get full text

A deep learning model for assistive decision-making during robot-aided rehabilitation therapies based on therapists’ demonstrations by David Martínez-Pascual, José M. Catalán, Luís D. Lledó, Andrea Blanco-Ivorra, Nicolás García-Aracil

“…It consists of diverse one-dimensional convolutional layers, a convolutional attention mechanism, and a Global Average Pooling layer. In addition, the output layer has one neuron with the sigmoid activation function, whose output can be interpreted as a probability of assistance. …”
Get full text

A new health literacy scale for staff in preschool childcare institution: development and preliminary validation by Xinqi Zhuang, Yitong Jia, Tianxin Cui, Ge Meng, Jianzhong Zhang, Linxia He, Yin-Ping Zhang

“…Methods The scale was developed through four phases. In Phase 1, an item pool was developed mainly based on literature review and kindergarten work; In Phase 2, the initial items were reviewed by fifteen experts and content validity analysis was conducted; In Phase 3, a pilot study was conducted involving 30 kindergarten staff, which aimed to further modify the scale; In Phase 4, a psychometric validation study involving 466 kindergarten staff was conducted through a cross-sectional survey in May 2023. …”
Get full text

Prevalence and Determinants of Home Delivery among Women with Easy Access to Health Facilities in Sub-Saharan African Countries: A Multi-level Mixed Effect Analysis by Berhan Tekeba, Alebachew Ferede Zegeye, Deresse Abebe Gebrehana, Tadesse Tarik Tamir

“…Factors with a p-value of < 0.05 are declared statistically significant. Results: The pooled prevalence of home delivery among women who had easy access to health facilities in 22 SSA countries was 23.67% (95% CI, 23.55–23.79). …”
Get full text

Biochemical composition of tomato fruits of various colors by A. B. Kurina, A. E. Solovieva, I. A. Khrapalova, A. M. Artemyeva

“…Mill. genetic resources collection includes 7678 accessions of one cultivated and nine wild species, which in turn provides ample opportunities for searching for information on the variability of the content of biologically active substances and searching for sources with a high content of them in the gene pool. Our work presents the results of the study of 70 accessions of cultivated and wild tomato on the main biochemical characteristics: the content of dry matter, ascorbic acid, sugars, carotenoids, chlorophylls and anthocyanins. …”
Get full text

Structural variability of sunflower gene for methionine-rich albumin SFA8 by I. N. Anisimova, N. V. Alpatieva, S. V. Goryunova, D. V. Goryunov, Al. V. Konarev, V. A. Gavrilova, E. E. Radchenko

“…In the cultivated sunflower gene pool the SFA8 structural gene is represented by the two alleles the products of which have different isoelectric points and differ by the electrophoretic mobility, however molecular mechanisms of the polymorphism are still unknown. …”
Get full text