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  1. 2221

    Risk factors for disruptive behaviours: protocol for a systematic review and meta-analysis of quasi-experimental evidence by Essi Viding, Francesca Solmi, Simon Russell, Lucy Karwatowska, Bianca Lucia De Stavola, Sara Jaffee, Jean-Baptiste Pingault

    Published 2020-09-01
    “…We will conduct meta-analyses if we can pool a minimum of three similar studies with the same or similar exposures and outcomes.Ethics and dissemination The proposed review does not require ethical approval. …”
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  2. 2222

    High-intensity statin therapy in patients with chronic kidney disease: a systematic review and meta-analysis by Jing Wang, Ling Wu, Yu-Ling Yan, Bo Qiu, Song-Bai Deng, Xiao-Dong Jing, Jian-Lin Du, Ya-Jie Liu, Qiang She

    Published 2015-05-01
    “…High-intensity statin also had obvious effects on lowering the LDL-C level but no clear effects on renal protection. Although pooled results showed no significant difference between the intervention and control groups in adverse event occurrences, it was still insufficient to put off the doubts that high-intensity statin might increase adverse events because of limited data sources and low quality evidences.Conclusions High-intensity statin therapy could effectively reduce the risk of stroke in patients with CKD. …”
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  3. 2223

    Balloon dilation for the treatment of male urethral strictures: a systematic review and meta-analysis by Tianyu Cai, Xiaoyu Li, Jian Lin, Chunru Xu, Xing Ji, Zhenpeng Zhu, Zhenke Guo

    Published 2024-02-01
    “…Stata V.14.0 was used for statistical analysis.Results Fifteen studies with 715 patients were ultimately included in this systematic review. The pooled results of eight studies showed that the reported success rate of simple balloon dilation for male urethral strictures was 67.07% (95% confidence interval [CI]: 55.92% to 77.36%). …”
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  4. 2224

    Antimicrobial resistance in wild game mammals: a glimpse into the contamination of wild habitats in a systematic review and meta-analysis by Claire Julie Akwongo, Luca Borrelli, Kurt Houf, Alessandro Fioretti, Maria Francesca Peruzy, Nicoletta Murru

    Published 2025-01-01
    “…Methods This study aimed to describe the prevalence of antibiotic-resistant bacteria in mammalian wild game, following the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. Results The overall pooled prevalence of antibiotic resistance was established at 59.8% while the prevalence of multidrug resistance (MDR) was 17.2%. …”
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  5. 2225

    Need to clamp indwelling urinary catheters before removal after different durations: a systematic review and meta-analysis by Xiaoyan Fan, Sumin Ma, Jiayi Gu

    Published 2023-02-01
    “…Categorical variables were analysed using relative risk (RR) and 95% CI.Primary and secondary outcome measures The primary outcome was urinary tract infection incidence, and secondary outcomes included hours to first voiding, incidence of urinary retention and recatheterisation and residual urine volume.Results Seventeen papers (15 RCTs and 2 quasi-RCTs) comprising 3908 participants were included in the meta-analysis. The pooled results of the meta-analysis showed that the clamping group had a significantly higher risk of urinary tract infections (RR=1.47; 95% CI 1.26 to 1.72; p<0.00001) and a longer hour to first void (SMD=0.19; 95% CI 0.08 to 0.29; p=0.0004) compared with the free drainage group. …”
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  6. 2226

    Causal relationship between ulcerative colitis and male infertility: A two-sample Mendelian randomization study. by Xia Wang, Tongyi Li, Qiu Chen

    Published 2024-01-01
    “…<h4>Methods</h4>Genetic loci closely associated with UC were extracted as instrumental variables and male infertility was the outcome variable in pooled data from the gene-wide association study (GWAS),which was derived from European ethnic groups. …”
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  7. 2227

    The Role of Probiotics in Managing Glucose Homeostasis in Adults with Prediabetes: A Systematic Review and Meta-Analysis by Chao Sun, Qingyin Liu, Xiaona Ye, Ronghua Li, Miaomiao Meng, Xingjun Han

    Published 2024-01-01
    “…A comprehensive literature search of the PubMed, Embase, and Cochrane Library databases was conducted through August 2022 to assess the impact of probiotics on blood glucose, lipid, and inflammatory markers in adults with prediabetes. Data were pooled using a random effects model and were expressed as standardized mean differences (SMDs) and 95% confidence interval (CI). …”
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  8. 2228

    Slight thermal stress exerts genetic diversity selection at coral (Acropora digitifera) larval stages by Cristiana Manullang, Nozomi Hanahara, Ariyo Imanuel Tarigan, Yuko Abe, Mao Furukawa, Masaya Morita

    Published 2025-01-01
    “…Although several studies have investigated coral larvae’s genetic responses to thermal stress, most relied on pooled sample sequencing, which provides population-level insights but may mask individual genotype variability. …”
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  9. 2229

    Association between triglyceride-glucose index and clinical outcomes among patients with chronic kidney disease: a meta-analysis by Jinli Tuo, Zhong Li, Linshen Xie

    Published 2025-02-01
    “…Results Twelve studies with 26,530 cases were included. Pooled results indicated that elevated TyG index was significantly related to increased risk for all-cause mortality (HR = 1.22, 95% CI: 1.13–1.31, P<0.001). …”
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  10. 2230

    Performance of artificial intelligence on cervical vertebral maturation assessment: a systematic review and meta-analysis by Termeh Sarrafan Sadeghi, Seyed AmirHossein Ourang, Fatemeh Sohrabniya, Soroush Sadr, Parnian Shobeiri, Saeed Reza Motamedian

    Published 2025-02-01
    “…Twelve studies were included in the meta-analysis and their pooled values for sensitivity, specificity, positive and negative likelihood ratios, and diagnostic odds ratio (DOR) were calculated for each cervical stage (CS). …”
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  11. 2231

    Comparison of Healthcare Encounters and Drug Persistence in Patients With Pulmonary Arterial Hypertension Receiving Oral Selexipag, Inhaled Iloprost, or Parenteral Treprostinil: A... by Ci Song, Peter Kunovszki, Amélie Beaudet

    Published 2022-06-01
    “…Mean (SD) age was 61.7 (14.5) and 49.3 (11.3) years, respectively; 74.4% and 75.7% of patients, respectively, were women. In the pooled samples, after adjustment for baseline characteristics, selexipag had a lower risk than inhaled iloprost or parenteral treprostinil for hospitalization (relative rate ratio [95% CI], 0.40 [0.22, 0.75], and 0.26 [0.17, 0.39]) and outpatient visits (0.66 [0.56, 0.78] and 0.76 [0.66, 0.88]). …”
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  12. 2232

    Prevalence of metal implants among US adults aged 40 years and older by Qiu-Fu Wang, Yu-Chen Tang, Hao-Ran Liao, Miao Lei, Wei Dong, Ze-Yu Liu, Jie Hao, Zhen-Ming Hu

    Published 2025-01-01
    “…Moreover, this study investigated the variation in metal implant prevalence by demographic factors based on the pooled NHANES cycles. All analyses were conducted based on 3,736 participants from the NHANES 2015–2016 and 6,387 participants from the NHANES 2017–March 2020. …”
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  13. 2233

    Efficacy and safety of pembrolizumab in patients with advanced endometrial cancer: a systematic review and meta-analysis by Biqiong Pan, Xiaojun Lai, Jiefang Lu, Xiaoyan Bao, Zengke Fan, Jie Sun

    Published 2025-02-01
    “…Single-arm studies: 8% CR and 4% PR in pembrolizumab-treated patients. Pooled AE incidence: 86%, with 43% grade 3/4. Two randomized controlled trials (RCTs) found that the pembrolizumab group had a higher incidence of grade 3 or 4 AEs compared to the control group (OR: 2.23; 95% CI: 1.23, 4.04; p = 0.008).ConclusionPembrolizumab monotherapy or combination significantly improves survival in recurrent or advanced EC and has manageable toxicity albeit with a relatively high incidence of treatment-related AEs.…”
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  14. 2234

    Safety profile of EZH2 inhibitors for cancer: a systematic review and meta-analysis by Zhou Zhao, Xiufeng Chen, Huayang Pang, Yan Shi, Hao Sun

    Published 2025-01-01
    “…The most frequently reported grade 3 or higher TRAEs in the pooled analysis were neutropenia (8%), thrombocytopenia (8%), and anemia (6%). …”
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  15. 2235

    Визначення віку людини за фото на основі нейронних мереж by Євгеній Вербенко, Ольга Мацуга

    Published 2024-06-01
    “…AlexNet впровадив використання ReLU-активації, dropout та max-pooling, тоді як VGG-19 підкреслив глибші архітектури з малими фільтрами. …”
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  16. 2236

    A meta-analysis of risk factors for cardiovascular adverse events with anthracycline based chemotherapy in lymphoma patients by Bo Dai, Jingjing Xu, Baiyan Wang

    Published 2025-01-01
    “…The results showed that pooled relative ratio for CAEs was 1.69 (95% CI: 1.39–2.06, p<0.001) for anthracyclines, and that risk factors for CAEs caused by anthracyclines included hypertension (RR = 2.15, 95% CI: 1.53–3.01, p < 0.001), radiation therapy (RR = 1.71, 95% CI: 1.19–2.47, p < 0.001), diabetes (RR = 1.57, 95% CI: 1.20–2.06, p<0.001), smoking (RR = 1.35, 95% CI: 0.96–1.88, p < 0.05), and age (RR = 1.16, 95% CI: 1.07–1.26, p < 0.001). …”
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  17. 2237

    The Association of Retinal Disease with Vision Impairment and Functional Status in Medicare Patients by Vincent Garmo, Xiaohui Zhao, Carmen D. Ng, Aimee Near, Tania Banerji, Keiko Wada, Gary Oderda, Diana Brixner, Joseph Biskupiak, Ferhina S. Ali, Archad M. Khanani, Alicia Menezes, Ibrahim M. Abbass

    Published 2024-03-01
    “…**Methods:** Medicare Current Beneficiary Survey data linked with Medicare Fee-for-Service claims data from 2006 to 2018 were used in a nationally representative retrospective pooled cross-sectional population-based comparison study. …”
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  18. 2238
  19. 2239

    Metformin as an adjuvant option for systemic treatment of breast cancer by D.I. Avierin, V.F. Zavizion

    Published 2023-12-01
    “…However, it should be considered that more aggressive therapy of oncological diseases can be a nosocomial selector of more aggressive clones of the pool of tumor cells. The main questions are whether metformin can be a targeted drug for the treatment of tumor, whether it is appropriate to use it at the time when the manifestation of evolution disturbances of tumor cell is minimal and homogeneity is maximal.…”
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  20. 2240