Alternative splicing for tuneable expression of protein subunits at desired ratios by Christel Aebischer-Gumy, Pierre Moretti, Timothee Brunstein Laplace, Jana Frank, Ysaline Grand, Farid Mosbaoui, Emilie Hily, Anna Galea, Megane Peltret, Carole Estoppey, Daniel Ayoub, Roberto Giovannini, Martin Bertschinger

“…The stability of the splice ratio was confirmed by droplet digital PCR in a stable pool cultivated over a 28-day period, while product quality was assessed via intact mass analysis, demonstrating absence of product-related impurities resulting from undesired splice events. …”
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Diffusion Tensor Imaging as Neurologic Predictor in Patients Affected by Traumatic Brain Injury: Scoping Review by Federica Paolini, Salvatore Marrone, Gianluca Scalia, Rosa Maria Gerardi, Lapo Bonosi, Umberto Emanuele Benigno, Sofia Musso, Alba Scerrati, Domenico Gerardo Iacopino, Francesco Signorelli, Rosario Maugeri, Massimiliano Visocchi

“…The aim was to identify all potentially relevant studies concerning the role of DTI in TBI. From an initial pool of 3527 publications, 26 articles were selected based on relevance. …”
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Ribosomal profiling as a tool for studying translation in plants: main results, problems and future prospects by D. A. Afonnikov, O. I. Sinitsyna, T. S. Golubeva, N. A. Shmakov, A. V. Kochetov

“…This technology includes the isolation of the polysomal fraction and high-performance sequencing of a pool of mRNA fragments associated with ribosomes. …”
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Detection and characterization of bovine hepacivirus in cattle and sheep from Hulunbuir, northeastern China by Jingge Ma, Jingge Ma, Zhiwei Wei, Liang Li, Wei Wang, Ziyan Liu, Ziyan Liu, Ning Liu, Feng Wei, Xiangyu Zheng, Zedong Wang

“…However, the genetic diversity, geographical distribution, and host range of the virus remains poorly understood.MethodsIn this study, serum samples from cattle and sheep were obtained in Hulunbuir and pooled to establish RNA libraries, which were then analyzed using transcriptome sequencing. …”
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Novel H16N3 avian influenza viruses isolated from migratory gulls in China in 2023 by Peng Peng, Peng Peng, Peng Peng, Jinyan Shen, Wenjun Shi, Jing Guo, Mengjing Wang, Wenxi Li, Zhiqin Yue, Xiaohong Sun, Mengdi Guan, Lili Liu, Hongke Xu, Yujiao Xie, Anran Ren, Mingfeng Liu, Wenqiang Liu, Zhibin Zhang, Zhibin Zhang, Zhishu Xiao, Zhishu Xiao, Xuyong Li

“…To fully understand the epidemiology and genetics characteristics of the global H16 viruses, we compared the host divergence of several rare subtypes and determined that the H13 and H16 subtypes were predominantly pooled into different species of gulls by sharing their internal genes, whereas the waterfowl of Anatidae served as the primary natural reservoirs of the H8, H11, H12, H14, and H15 subtypes. …”
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The Association Between Periodontitis, Gingivitis, Tooth Loss and Stroke: An Umbrella Study with Meta-Analysis by Jad El Masri, Ahmad Al Malak, Diala El Masri, Maya Ghazi, Silva Al Boussi, Yasmina El Masri, Mohammad Hassoun, Maryam Tlayss, Pascale Salameh, Hassan Hosseini

“…Assessment of Multiple Systematic Reviews (AMSTAR) was used for quality assessment. Pooled analysis was performed to assess the effect of periodontitis, gingivitis and tooth loss on CVA, depending on the availability of data using Review Manager Version 5.2.11. …”
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The development of the Cough Hypersensitivity Questionnaire for chronic cough by Barnaby Hirons, Peter S.P. Cho, Chris Krägeloh, Richard J. Siegert, Richard Turner, Katherine Rhatigan, Harini Kesavan, Ewan Mackay, Ha-Kyeong Won, Ju-Young Kim, Woo-Jung Song, Surinder S. Birring

“…Results Concept elicitation created a pool of 34 items. Eleven items were removed following multidisciplinary team review of patient interviews. …”
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Optimal treatment approach for intracranial germinoma: a systematic review and meta-analysis by Zhirui Zhou, Jiabing Liu, Qi Yue, Lingxiao Chen, Xiwei Zhang, Xin Lin, Lin Zheng, Enmin Wang, Yang Wang, Ying Mao

“…Materials and methods A search of Medline, Embase, Web of Science and Cochrane Library was conducted up to April, 2024. Pooled risk ratio (RR) and 95% confidence interval (CI) were calculated. …”
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Surgery and Medical Treatment in Microprolactinoma: A Systematic Review and Meta-Analysis by Jianglong Lu, Lin Cai, Zerui Wu, Weiwei Lin, Jiadong Xu, Zhangzhang Zhu, Chengde Wang, Qun Li, Zhipeng Su

“…The I2 statistic was used to quantify heterogeneity. Pooled data were analysed according to a random effect model. …”
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Effect of dietary starch inclusion, feeding level and their combination on nutrient digestibility, bile acid balance, faecal waste production and characteristics of yellowtail king... by Yaqing Zhang, Roel M. Maas, Peter Horstmann Zuther, Jeroen Kals, Satya Prakash, Thomas W.O. Staessen, Fotini Kokou, Johan W. Schrama

“…The latter was associated with a potential depletion of the body bile acid pool as bile acid balances (bile acid intake – faecal bile acid loss) were consistently negative for all diets during both feeding periods. …”
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Microencapsulation of Probiotic Strains by Lyophilization Is Efficient in Maintaining the Viability of Microorganisms and Modulation of Fecal Microbiota in Cats by Bruna M. Rodrigues, Paula M. Olivo, Milene P. Osmari, Ricardo S. Vasconcellos, Leonir B. Ribeiro, Ferenc I. Bankuti, Magali S. S. Pozza

“…Fructooligosaccharides and gum arabic were used as encapsulating agents for freeze drying and spray drying and a pool containing Lactobacillus acidophilus, Lactobacillus casei, Lactobacillus lactis, Bifidobacterium bifidum, Enterococcus faecium, and Saccharomyces cerevisiae as a probiotic. …”
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Dipeptidyl Peptidase 4 Activity Is Related to Body Composition, Measures of Adiposity, and Insulin Resistance in Subjects with Excessive Adiposity and Different Degrees of Glucose... by Wellington S. Silva Júnior, Maria das Graças C. Souza, José Firmino Nogueira Neto, Eliete Bouskela, Luiz Guilherme Kraemer-Aguiar

“…DPP4 activity was no different among the three groups. At fasting, pooled analysis showed it was positively correlated with measures of central adiposity, such as WC (P=0.011) and WHR (P=0.009), and with all measures of IR, but inversely related to indexes of general adiposity, such as fat mass percentage (P=0.014) and BAI (P=0.0003). …”
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Meta Analysis of Efficacy and Safety of Prostate Biopsy: A Comparison Between Transperineal and Transrectal Approach by Syah Mirsya Warli, Stivano Rizky Valentino Torry, Dhirajaya Dharma Kadar, Ginanda Putra Siregar, Fauriski Febrian Prapiska

“…A total of 19 publications, involving 80133 patients with suspicion of prostate cancer who underwent prostate biopsy, were enrolled in the analysis. The pooled estimate demonstrated no significant differences in the cancer detection rate between TR and TP (risk difference (RD)=0.03; 95% CI: −0.01 to 0.08; P = .12). …”
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Association of non-selective β blockers with the development of renal dysfunction in liver cirrhosis: a systematic review and meta-analysis by Xiangbo Xu, Fangbo Gao, Ting Wang, Zuyao Yang, Qingchun Zhao, Xingshun Qi

“…Odds ratios (ORs) and hazard ratios (HRs) were pooled. Subgroup meta-analyses were performed according to the proportions of ascites and Child-Pugh class B/C and the mean model for end-stage liver disease (MELD) score. …”
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Prognostic significance of programmed cell death 1 expression on CD8+T cells in various cancers: a systematic review and meta-analysis by Zhiyong Wan, Meng Cui, Jia Yang, Dan Liao, Junliang Chen, Fanmin Li, Yin Xiang, Zhiwei Cui, Yang Yang

“…The PubMed, Web of Science, Embase databases were searched from inception to November 2024. The pooled Hazard Ratio (HR) along with 95% confidence intervals (CIs) of each article were combined for the associations of PD-1+CD8+ T cells with overall survival (OS), progression- free survival (PFS) and disease-free survival(DFS). …”
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Effect of exercise training on cardiac autonomic function in type 2 diabetes mellitus: a systematic review and meta-analysis by Sohini Raje, G Arun Maiya, Padmakumar R, Mukund A. Prabhu, Krishnananda Nayak, Shivashankara KN, BA Shastry, Megha Nataraj

“…The studies did not show any influence on the E:I and 30:15 ratio in the pooled analysis with a low risk of ineffectiveness for the exercise intervention. …”
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Burden of intestinal parasites among diabetic patients in Africa: a systematic review and meta-analysis by Marye Nigatie Debash, Getinet Kumie, Assefa Sisay, Solomon Gedfie, Wagaw Abebe, Agenagnew Ashagre, Tadesse Misganaw, Habtu Debash, Melese Abate Reta

“…Results In the current systematic review and meta-analysis, the pooled prevalence of intestinal parasites in diabetic patients was 31% (95% CI: 23–38%) with heterogeneity of I2 = 95.94%; P < 0.001. …”
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Protocol for a systematic review on routine use of antibiotics for infants less than 6 months of age with growth failure/faltering by Jai K Das, Zulfiqar Ahmed Bhutta, Abigail Smith, Aamer Imdad, Emily Tanner-Smith, Melissa François, Fanny F Chen, Olivia J Tsistinas

“…We will use the meta-analysis to pool the studies where applicable. We will use the Grading of Recommendations Assessment, Development, and Evaluation approach to reporting the overall evidence quality for an outcome.Ethics and dissemination This is a systematic review and will not involve contact with a human subject. …”
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Cardiovascular and renal safety outcomes of hypoxia-inducible factor prolyl-hydroxylase inhibitor roxadustat for anemia patients with chronic kidney disease: a systematic review an... by Lei Tian, Mengdi Wang, Mengchao Liu, Yanyu Pang, Jingwen Zhao, Bingjie Zheng, Yutong Wang, Wenjing Zhao

“…We employed a fixed-effects model for analysis. The pooled result revealed no significant difference in the risk of occurrence of cardiac disorders when comparing CKD patients receiving roxadustat with the placebo (RR = 1.049; CI [0.918 to 1.200]) or ESA (RR = 1.066; CI [0.919 to 1.235]), in both dialysis-dependent (DD) (RR = 1.094; CI [0.925 to 1.293]) or non-dialysis-dependent (NDD) (RR = 1.036; CI [0.916 to 1.171]) CKD patients. …”
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Pharmacological interventions for hidradenitis suppurativa: a protocol for systematic review and network meta-analysis of randomised trials and non-randomised studies by Phichayut Phinyo, Surapon Nochaiwong, Naritthorn Aroonsakul, Lalita Lumkul, Nutcha Jarupanich, Jacek Szepietowski, Mati Chuamanochan

“…Based on a random-effects model, standardised weighted mean differences and ORs with corresponding 95% CIs will be pooled as effect estimates for the continuous and categorical endpoints, respectively. …”
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