Polymeric nanoreactors for catalytic applications by Abou-Fayssal, Chantal Joseph, Poli, Rinaldo, Philippot, Karine, Riisager, Anders, Manoury, Eric

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Comparative Analysis of Seventeen Mitochondrial Genomes of Mileewinae Leafhoppers, Including the Unique Species Mileewa digitata (Hemiptera: Cicadellidae: Mileewinae) From Xizang,... by Hongli He, Bin Yan, Xiaofei Yu, Maofa Yang

“…Notably, the genome of the Xizang endemic Mileewa digitata measures 15,280 bp, with an AT content of 80.7%, 10,941 bp of PCGs, and a 949 bp control region (CR) followed by a 19 bp poly‐A tail. Gene arrangement among the 17 genomes mirrors that of other Mileewinae species. …”
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Synthesis, Characterization, and In Vivo Cytokinome Profile of IL-12-Loaded PLGA Nanospheres by Ryan A. Lacinski, Justin E. Markel, Jabeen Noore, Hillary G. Pratt, Brock A. Lindsey

“…We report the successful encapsulation and elution of recombinant murine IL-12 (rmIL-12) from poly(lactide-co-glycolic) acid (PLGA) nanospheres (IL-12-NS) synthesized using the double emulsion/solvent evaporation (DESE) technique with microsphere depletion through ultracentrifugation. …”
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Factors Related to Oral Health-Related Quality of Life of Independent Brazilian Elderly by Karla Giovana Bavaresco Ulinski, Mariele Andrade do Nascimento, Arinilson Moreira Chaves Lima, Ana Raquel Benetti, Regina Célia Poli-Frederico, Karen Barros Parron Fernandes, Marina Lourdes Calvo Fracasso, Sandra Mara Maciel

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In silico analysis of SNPs and miRNAs of KCTD13, CSDE1, SLC6A1 genes associated with autism spectrum disorder by Kübra Çoruh Kınalı, Ebru Özkan Oktay, Mesut Karahan

“…This data served as input for predictions, which were carried out using different computational tools like SIFT, PolyPhen-2, SNPs&GO, PROVEAN, MutationAssessor, PhD-SNP, PANTHER, SNAP-2, Meta-SNP, I-Mutant 2.0, MUpro, and Project HOPE. …”
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Stem Cell Transplantation for Ovarian Cancer Patient with Associated Myelodysplasia After Maintenance Therapy with Olaparib: A Case Report by Linn Z, Gu Z, Wang L, Cai S

“…Zeyar Linn,1 Zhongyi Gu,1 Libing Wang,2 Shengyun Cai1 1Department of Obstetrics and Gynecology, The First Affiliated Hospital of Naval Medical University (Changhai Hospital), Naval Medical University, Shanghai, People’s Republic of China; 2Department of Hematology, The First Affiliated Hospital of Naval Medical University (Changhai Hospital), Naval Medical University, Shanghai, People’s Republic of ChinaCorrespondence: Shengyun Cai, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Naval Medical University (Changhai Hospital), Naval Medical University, 168 Changhai Road, Shanghai, 200433, People’s Republic of China, Email caicai24@126.comAbstract: Ovarian cancer remains a significant cause of morbidity and mortality in women worldwide. Olaparib, a poly ADP-ribose polymerase (PARP) inhibitor, has been shown in studies to increase the time that people with cancer do not get worse. …”
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PHILOSOPHICAL AND PSYCHOLOGICAL DIMENSIONS OF SOCIAL EXPECTATIONS OF PERSONALITY by V. V. Khmil, I. S. Popovych

“…The role of social institutions in the formation of expectations is outlined. The poly-aspect of the investigated problems is shown. …”
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CARACTERIZACIÓN DE COPRODUCTOS DE LA INDUSTRIA DEL FILETEADO DE TILAPIA NILÓTICA (Oreochromis niloticus) Y TRUCHA ARCOÍRIS (Oncorhynchus mykiss) EN COLOMBIA by A. Osorio, A. Wills, A. P. Muñoz

“…Los resultados muestran que los coproductos estudiados contienen un importante aporte de proteína, cenizas, ácidos grasos poli-insaturados y adecuada calidad microbiológica, con potencial para alimentación humana o animal.…”
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Finding Ways to Lift Barriers to Care for Chronic Pain Patients: Outcomes of Using Internet-Based Self-Management Activities to Reduce Pain and Improve Quality of Life by Kevin Rod

“…Two hundred (200) patients (61% females, 39% males, between 18 and 75 years old) from one community pain clinic in Toronto, Canada (Toronto Poly Clinic), participated. Patients had moderate to severe pain, depression, and anxiety. …”
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Evaluation of one-point fixation for zygomaticomaxillary complex fractures using a three-dimensional photogrammetric analysis by Se Young Kim, Seung Min Nam, Eun Soo Park, Yong Bae Kim

“…Methods From March 2014 to December 2014, 34 patients with ZMC fractures were treated by one-point fixation in the ZM buttress using unsintered hydroxyapatite (u-HA)/poly-L-lactide (PLLA) plates. Differences in soft tissue inter-malar height between the fractured side and unfractured sides were evaluated using photogrammetric analysis with a three-dimensional camera (Morphius®) at the preoperative and 1 week, 1 and 3 months after surgery. …”
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Activities of Some Medicinal Plants on the Proliferation and Invasion of Brain Tumor Cell Lines by Saidu I. Ngulde, Umar K. Sandabe, Roger Abounader, Ying Zhang, Isa M. Hussaini

“…U87 and U231 brain tumor cell lines were used for proliferation assay, U251 cell line was used for the invasion assay in collagen V coated inserts, and U87 cell line was used for the western blot detection of cleaved Poly-ADP-Ribose-Polymerase (PARP). The result revealed that all tested extracts significantly (p<0.05) inhibited the proliferation of U87 and U231 cell lines with the respective IC50 values ranging between 8 and 20 μg/ml for S. longepedunculata and 100 and 90 μg/ml for P. polyandra. …”
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Monoallelic variants resulting in substitutions of MAB21L1 Arg51 Cause Aniridia and microphthalmia. by Hildegard Nikki Hall, Hemant Bengani, Robert B Hufnagel, Giuseppe Damante, Morad Ansari, Joseph A Marsh, Graeme R Grimes, Alex von Kriegsheim, David Moore, Lisa McKie, Jamalia Rahmat, Catia Mio, Moira Blyth, Wee Teik Keng, Lily Islam, Meriel McEntargart, Marcel M Mannens, Veronica Van Heyningen, Joe Rainger, Brian P Brooks, David R FitzPatrick

“…Mass spectrometry of immunoprecipitated protein revealed that both mutant and wildtype MAB21L1 associate with transcription factors that are known regulators of PAX6 (MEIS1, MEIS2 and PBX1) and with poly(A) RNA binding proteins. Arg51 substitutions reduce the association of wild-type MAB21L1 with TBL1XR1, a component of the NCoR complex. …”
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PARP inhibitors as therapy for small cell lung carcinoma: A systematic review and meta-analysis of clinical trials by Samuel Pratama, Lowilius Wiyono, Martien Silviandy Setiawan, Brigitta Cindy Lauren

“…Background: Small Cell Lung Cancer (SCLC) is a neuroendocrine carcinoma characterized by aggressive behavior and poor prognosis with limited treatment options. Poly ADP-Ribose Polymerase inhibitors (PARPi) are novel anti-cancer agents that induce DNA damages and cause cell death in tumor cells with impaired DNA repair, known as the synthetic lethality concept. …”
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Design, Implementation and Environmental Impact of Cutoff Wall for Pollution Control in an Industrial Legacy Site by Lu Yu, Sichen Chen, Jinnan Wang, Zhihong Zhang, Yan Huang

“…Firstly, the concentrations and spatial distributions of Pb, Cd and polychlorinated biphenyls (PCBs) and poly brominated diphenyl ethers (PBDEs) were identified in both soil and groundwater. …”
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Development and evaluation of a novel E7 multi-epitopic vaccine for human papillomavirus type 16: design, expression, purification, and immunological characterization by Bahareh Bahmani, Zahra Amini-bayat, Mohammad Mehdi Ranjbar, Masoud Hassanzadeh Makoui, Amir-Hassan Zarnani

“…Immunization of TC-1 tumor-bearing mice with HPV16-E7, markedly delayed tumor growth and propagation. Conclusion The poly-epitope vaccine for HPV16-E7, as expressed and purified in this research, is highly immunogenic and capable of triggering E7-specific antibodies, making it a potential therapeutic HPV vaccine. …”
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Identification of the Highly Polymorphic Prion Protein Gene (<i>PRNP</i>) in Frogs <i>(Rana dybowskii</i>) by Chang-Su Han, Sae-Young Won, Sang-Hun Park, Yong-Chan Kim

“…We carried out in silico analyses to predict functional alterations according to non-synonymous single nucleotide polymorphisms (SNPs) using PolyPhen-2, PANTHER, SIFT, and MutPred2. We used ClustalW2 and MEGA X to compare frog <i>PRNP</i> and PrP sequences with those of prion-related animals. …”
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Development of a psychological frailty index: results from the China health and retirement longitudinal study by Jinlong Zhao, Justina Yat Wa Liu, Justina Yat Wa Liu, Daniel Fernández, Stefanos Tyrovolas, Stefanos Tyrovolas, Stefanos Tyrovolas, Stefanos Tyrovolas

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Incidence and risk of endocrine and metabolic abnormalities linked to PARP inhibitors in solid tumors: a meta-analysis by Shunlian Fu, Pingjin Zou, Zengyi Fang, Xinxiang Zhou, Junyang Chen, Cuicui Gong, Li Quan, Bing Lin, Qiu Chen, Jinyi Lang, Meihua Chen

“…Abstract Background Poly (ADP-ribose) polymerase inhibitors (PARPi) serve as crucial therapeutic agents in solid tumor treatment. …”
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PBMCs gene expression predicts liver fibrosis regression after successful HCV therapy in HIV/HCV-coinfected patients by Ana Virseda-Berdices, Ana Virseda-Berdices, Óscar Brochado-Kith, Óscar Brochado-Kith, Juan Berenguer, Juan Berenguer, Juan Berenguer, Juan González-García, Juan González-García, Juan González-García, Leire Pérez-Latorre, Leire Pérez-Latorre, Leire Pérez-Latorre, Carmen Busca, Carmen Busca, Carmen Busca, Cristina Díez, Cristina Díez, Cristina Díez, Rafael Micán, Rafael Micán, Rafael Micán, Amanda Fernández-Rodríguez, Amanda Fernández-Rodríguez, María Ángeles Jiménez-Sousa, María Ángeles Jiménez-Sousa, Salvador Resino, Salvador Resino

“…Total RNA was extracted from PBMCs at baseline, and poly(A) RNA sequencing was performed. The outcome was an LSM reduction greater than 50% (LSMred&gt;50%) about 48 weeks after HCV treatment.ResultsSeven patients (14.5%) reduced LSM by over 50%. …”
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Effect of Inflammation on Gingival Mesenchymal Stem/Progenitor Cells’ Proliferation and Migration through Microperforated Membranes: An In Vitro Study by M. Al Bahrawy, K. Ghaffar, A. Gamal, K. El-Sayed, V. Iacono

“…Clones of human gingival mesenchymal stem/progenitor cells (GMSCs) from inflamed gingival tissues were characterized for stem/progenitor cells’ characteristics and compared to clones of healthy human GMSCs (n=3), to be subsequently seeded on perforated collagen-coated poly-tetra-floro-ethylene (PTFE) membranes with a pore size 0.4 and 3 microns and polycarbonic acid membranes of 8 microns pore size in Transwell systems. …”
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