In-silico screening and analysis of missense SNPs in human CYP3A4/5 affecting drug-enzyme interactions of FDA-approved COVID-19 antiviral drugs by Amro A. Abdelazim, Mohamad Maged, Ahmed I. Abdelmaksoud, Sameh E. Hassanein

“…An ensemble of bioinformatics tools, [SIFT, PolyPhen-2, cadd, revel, metaLr, mutation assessor, Panther, SNP&GO, PhD-SNP, SNAP, Meta-SNP, FATHMM, I-Mutant, MuPro, INPS, CONSURF, GPS 5.0, MusiteDeep and NetPhos], identified a total of 94 variants (47 SNPs in CYP3A4, 47 SNPs in CYP3A5) to potentially impact the structural integrity as well as the activity of the CYP3A4/5 enzymes. …”
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Qualidade de dados baseada em probabilidades para reconstrução da energia em calorimetria de altas energias by Sarita de Miranda Rimes, Bernardo Sotto-Maior Peralva, Luciano Manhães de Andrade Filho, José Manoel de Seixas

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Data-independent LC-MS/MS analysis of ME/CFS plasma reveals a dysregulated coagulation system, endothelial dysfunction, downregulation of complement machinery by Massimo Nunes, Mare Vlok, Amy Proal, Douglas B. Kell, Etheresia Pretorius

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Visual Outcome Ambliopia Refraktif Yang Mendapat Cam Vision Stimulator Di RS. M. Djamil Padang Januari-Desember 2017 by Suci Fitri, Julita Julita

“…Partisipan adalah pasien di Poli Mata subbagian Pediatrik dan Strabismus yang sudah didiagnosa sebagai ambliopia refraktif dan sudah mendapat dan memakai koreksi kacamata selama satu bulan. …”
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The Effect of IL-35 on the Expression of Nasal Epithelial-Derived Proinflammatory Cytokines by Mingrong Nie, Qingxiang Zeng, Luo Xi, Yiquan Tang, Renzhong Luo, Wenlong Liu

“…AR mice were developed to verify the effect of IL-35 on nasal epithelial cells in vivo. Results. After Poly I:C stimulation, IL-35 inhibited the production of IL-25, and TSLP from HNECs increased significantly compared with baseline levels (P<0.05). …”
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Layer-by-Layer Fabrication of PAH/PAMAM/Nano-CaCO3 Composite Films and Characterization for Enhanced Biocompatibility by Naemi Tonateni Shifeta, Shindume Lomboleni Hamukwaya, Qi An, Huiying Hao, Melvin Mununuri Mashingaidze

“…Polymer composites constituted of poly(amidoamine) (PAMAM), polyallylamine hydrochloride (PAH), and calcium carbonate (CaCO3) nanoparticles have good biocompatibility with physiological tissue and fluids, making them excellent candidates for biomedical applications. …”
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PMDNet: An Improved Object Detection Model for Wheat Field Weed by Zhengyuan Qi, Jun Wang

“…PMDNet incorporates the Poly Kernel Inception Network (PKINet) as the backbone, the self-designed Multi-Scale Feature Pyramid Network (MSFPN) for multi-scale feature fusion, and Dynamic Head (DyHead) as the detection head, resulting in significant performance improvements. …”
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Gengnianchun Recipe Protects Ovarian Reserve of Rats Treated by 4-Vinylcyclohexene Diepoxide via the AKT Pathway by Fangui Zhao, Wenjun Wang

“…Proapoptosis proteins of Bax, cleaved caspase-3, and poly ADP-ribose polymerase (PARP) were significantly decreased after high-dose GNC treatment compared with those in the model group. …”
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Piezoelectric-triboelectric hybrid nanogenerator based on tough, stretchable BaTiO3 doped antibacterial hydrogel for self-powered sensors by Runi Hou, Lijian Xu, Maolin Yu, Zengmin Tang, Bin Zhou, Qiao Zhang, Na Li, Jianxiong Xu

“…To this end, a functional hydrogel of oxidized sodium alginate (OSA) crosslinked poly(acrylic acid-co-acrylamide) (P(AA-co-AM)) in the presence of BaTiO3 (BTO) nanoparticles was initially prepared and then immersed in FeCl3 solution to form OSA/P(AA-co-AM)/Fe3+-BTO (O/P/Fe-BTO) hydrogels. …”
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Bioresorbable Material in Secondary Orbital Reconstruction Surgery by Hui Pan, Zhenzhen Zhang, Weiwei Tang, Zhengkang Li, Yuan Deng

“…All 16 patients had primary orbital implants consisting of Medpor, titanium mesh, hydroxyapatite, or poly-L-lactide. Of the 16 cases, 14 had malpositioned implants posteriorly and two had implant infections. …”
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Characterization of H460R, a Radioresistant Human Lung Cancer Cell Line, and Involvement of Syntrophin Beta 2 (SNTB2) in Radioresistance by Chang-Nim Im, Byeong Mo Kim, Eun-Yi Moon, Da-Won Hong, Joung Whan Park, Sung Hee Hong

“…In addition, H460R cells were resistant to IR, exhibiting reduced expression levels of ionizing responsive proteins (p-p53 and γ-H2AX); apoptosis-related molecules, such as cleaved poly(ADP ribose) polymerase; and endoplasmic reticulum stress-related molecules, such as glucose-regulated protein (GRP78) and C/EBP-homologous protein compared with parental cells, whereas the expression of anti-apoptotic X-linked inhibitor of apoptosis protein was increased. …”
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Release Profile and Antibacterial Activity of <i>Thymus sibthorpii</i> Essential Oil-Incorporated, Optimally Stabilized Type I Collagen Hydrogels by Caglar Ersanli, Ioannis Skoufos, Konstantina Fotou, Athina Tzora, Yves Bayon, Despoina Mari, Eleftheria Sarafi, Konstantina Nikolaou, Dimitrios I. Zeugolis

“…At first, the optimally stabilized type I collagen hydrogels via six different multi-arm poly (ethylene glycol) succinimidyl glutarate (starPEG) crosslinkers were determined by assessing the free amine content and the resistance to enzymatic degradation. …”
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Flanking monomer repeats define lower context complexity of sites containing single nucleotide polymorphisms in the human genome by N. S. Safronova, M. P. Ponomarenko, I. I. Abnizova, G. V. Orlova, I. V. Chadaeva, Y. L. Orlov

“…Such oligonucleotides are related to nucleotide polytracks. The presence of poly-A tracks might be associated with an increased probability of double helix DNA breaks around mutable loci and following fixation of nucleotide changes. …”
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Scalable Manufacturing Method for Model Protein-Loaded PLGA Nanoparticles: Biocompatibility, Trafficking and Release Properties by Selin Akpinar Adscheid, Marta Rojas-Rodríguez, Salma M. Abdel-Hafez, Francesco S. Pavone, Marc Schneider, Akif E. Türeli, Martino Calamai, Nazende Günday-Türeli

“…Among DDSs, polymeric nanoparticles (NPs), particularly poly(lactic-co-glycolic acid) (PLGA) NPs, hold an outstanding position due to their biocompatible and biodegradable qualities. …”
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Classification Based on the Support Vector Machine for Determining Operational Targets for Controlling Electricity Usage With Conventional Meters: A Case Study of Industrial and Bu... by Galih Arisona, Alief Pascal Taruna, Dwi Irwanto, Arif Bijak Bestari, Wildan Juniawan

“…Various SVM kernels were tested, including Radial Basis Function (RBF), Linear, Polynomial (Poly), and Sigmoid, alongside classifiers such as SVM, Logistic Regression, Decision Tree, and Na&#x00EF;ve Bayes. …”
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A new peptide inhibitor of C1QBP exhibits potent anti‐tumour activity against triple negative breast cancer by impairing mitochondrial function and suppressing homologous recombina... by Xingxing Li, Yue Wu, Min Zhang, Fengliang Wang, Hong Yin, Yanrong Zhang, Shuli Zhao, Jiehua Ma, Mingming Lv, Cheng Lu

“…Furthermore, PDBAG1 inhibits homologous recombination repair proteins and facilitates synergism with poly‐ADP‐ribose polymerase inhibitors in cancer therapy. …”
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Stabilization of metal-doped magnesium oxide nanoparticles with PAMAM dendrimers to improve alpha-amylase enzyme inhibition by Jaison Jeevanandam, Mara Gonçalves, Rita Castro, Juan Gallo, Manuel Bañobre-López, João Rodrigues

“…The present study aimed to synthesize metal-doped magnesium oxide (MgO) nanoparticles to drastically reduce polydispersity and stabilize them with generation 5 of poly(amidoamine) (G5 PAMAM) dendrimers to assess their antidiabetic properties via controlled release. …”
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Sulfur/reduced graphite oxide and dual-anion solid polymer‒electrolyte integrated structure for high-loading practical all-solid-state lithium–sulfur batteries by Eun Mi Kim, Jinseok Han, Guk-Tae Kim, Huan Li, Meng Yang Cui, Ganghwan Park, Dong-Ho Baek, Bo Jin, Sang Mun Jeong, Jae-Kwang Kim

“…In detail, S particles dispersed in a functionalized reduced graphite oxide (rGO) cathode with a binder-less polymer electrolyte (PE) and a dual-anion ionic liquid-containing cross-linked poly(ethylene oxide)–Li bis(fluoromethanesulfonyl)imide–N-butyl-N-methylpyrrolidinium bis(trifluoromethanesulfonyl) imide-based solid polymer electrolyte (SPE, PEO–LiFSI0.1(Pyr14TFSI)0.4) were hot-pressed into an integrated electrode, which serves as both the cathode and electrolyte. …”
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Antifungal Activity of Denture Base Resin Containing Nanozirconia: In Vitro Assessment of Candida albicans Biofilm by Reem Abualsaud, Doaa M. Aleraky, Sultan Akhtar, Soban Q. Khan, Mohammed M. Gad

“…To evaluate the antimicrobial effects of different concentrations of zirconium dioxide nanoparticles (nano-ZrO2) reinforcement of poly(methyl) methacrylate (PMMA) on surface roughness and C. albicans biofilm. …”
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Increased Risk of Dementia in Patients with Antidepressants: A Meta-Analysis of Observational Studies by Yao-Chin Wang, Po-An Tai, Tahmina Nasrin Poly, Md Mohaimenul Islam, Hsuan-Chia Yang, Chieh-Chen Wu, Yu-Chuan (Jack) Li

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