A ROS-responsive hydrogel encapsulated with matrix metalloproteinase-13 siRNA nanocarriers to attenuate osteoarthritis progression by Qiuyang Wang, Kai Feng, Guangsheng Wan, Wei Liao, Jing Jin, Peng Wang, Xiaolian Sun, Weijun Wang, Qing Jiang

“…In this study, matrix metalloproteinase-13 siRNA (siMMP-13) was incorporated onto polyethylenimine (PEI)-polyethylene glycol (PEG) modified Fe3O4 nanoparticles, forming a nucleic acid nanocarrier termed si-Fe NPs. Subsequently, a poly(vinyl alcohol) (PVA) crosslinked phenylboronic acid (PBA)-modified hyaluronic acid (HA) hydrogel (HPP) was used to encapsulate the si-Fe NPs, resulting in a bifunctional hydrogel (si-Fe-HPP) with reactive oxygen species (ROS)-responsive and RNAi therapeutic properties. …”
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Human embryonic stem cells cultured on hydrogels grafted with extracellular matrix protein‐derived peptides with polyethylene glycol joint nanosegments by Abdullah A. Alarfaj, Abdurahman H. Hirad, Murugan A. Munusamy, S. Suresh Kumar, Akon Higuchi

“…Vitronectin‐derived peptides with glycine joint nanosegments (GCGG) were conjugated onto poly (vinyl alcohol‐co‐itaconic acid) hydrogels via PEG joint nanosegments, and human embryonic stem cells (hESCs) were cultivated on these hydrogels. hESCs could successfully be cultivated on hydrogels while maintaining their pluripotency and differentiation potential to differentiate into cells that are induced from three germ layers in vitro and in vivo, where only a 50 μg/ml ECM‐derived peptide concentration was used when the PEG joint nanosegments were introduced into peptides that were grafted onto hydrogel surfaces. …”
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Placement of an elastic, biohybrid patch in a model of right heart failure with pulmonary artery banding by Yasunari Hayashi, Yasunari Hayashi, Seungil Kim, Seungil Kim, Seungil Kim, Taro Fujii, Taro Fujii, Drake Dalton Pedersen, Drake Dalton Pedersen, Takahiro Ozeki, Takahiro Ozeki, Hongbin Jiang, Antonio D’Amore, Antonio D’Amore, Antonio D’Amore, Antonio D’Amore, Antonio D’Amore, William R. Wagner, William R. Wagner, William R. Wagner

“…Biohybrid cardiac patches were generated by co-processing biodegradable poly(ester carbonate urethane) urea (PECUU) and a digest of the porcine cardiac extracellular matrix. …”
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Hubungan Aktivitas Fisik Dengan Kualitas Tidur Pasien Pascastroke Di Rumah Sakit Khusus Daerah Dadi Provinsi Sulawesi Selatan by Rini Maghfirah, Meutiah Mutmainnah Abdullah, Ita Rini

“…Subjek penelitian ini adalah pasien pascastroke rawat jalan di poli fisioterapi Stroke Center RSKD Dadi Provinsi Sulsel yang berjumlah 33 orang. …”
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Processing streams in a monitoring cloud cluster by Alexey N. Nazarov

“…In the conditions of high dynamics of changes in the bit rate of information generation from the source, a model of the bit rate of Discretized Stream (DStream) formation is proposed, which has a common application. Based on the poly-burst nature of the bit rate model, a model of group content traffic of any sources of different services processed in the cloud cluster was created. …”
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Design of Polymer Blends Based on Chitosan:POZ with Improved Dielectric Constant for Application in Polymer Electrolytes and Flexible Electronics by Shujahadeen B. Aziz, M. H. Hamsan, M. F. Z. Kadir, H. J. Woo

“…There is a considerable demand for the development and application of polymer materials in the flexible electronic- and polymer-based electrolyte technologies. Chitosan (CS) and poly(2-ethyl-2-oxazoline) (POZ) materials were blended with different ratios to obtain CS:POZ blend films using a straightforward solution cast technique. …”
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An In silico Approach towards Finding the Cancer-Causing Mutations in Human MET Gene by Fayeza Sadia Laskar, Md. Nazmul Islam Bappy, Md. Sowrov Hossain, Zenifer Alam, Dilruba Afrin, Sudeb Saha, Kazi Md. Ali Zinnah

“…These nsSNPs were first identified utilizing computational tools like SIFT, PROVEAN, PANTHER-PSEP, PolyPhen-2, I-Mutant 2.0, and MUpro. A total of 45359 SNPs of MET gene were accumulated from the database of dbSNP, and among them, 1306 SNPs were identified as non-synonymous or missense variants. …”
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Rheology of concentrated crystal suspensions: sucrose fondants as hard particles in soft matter by Hannah M. Hartge, Hannah M. Hartge, Eckhard Flöter, Thomas A. Vilgis

“…However, the complex rheological behavior of such non-colloidal suspensions with poly-disperse, irregular particles is not fully understood. …”
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Surgical Treatment of Peri-Implantitis: A 17-Year Follow-Up Clinical Case Report by Fabrizio Bassi, Pier Paolo Poli, Davide Rancitelli, Fabrizio Signorino, Carlo Maiorana

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A Multiregion Discrete-Time Epidemic Model of Mycobacterium tuberculosis Infections: An Optimal Control Approach by Rachid Bouajaji, Hassan Laarabi, Mostafa Rachik, Abdelhadi Abta

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ANTHROPOLOGIZATION OF SCIENCE: FROM THE SUBJECT OF COGNITION TO THE RESEARCHER’S PERSONALITY by N. V. Kryvtsova, I. A. Donnikova

“…Including the concept of the subject of cognition in the ontology of the unity of difference-multidimensional poly-essential autopoetic integrity, the anthropologization of science is intended to revive the ancient idea in the unity of truth ("ἀλήθεια"), education ("παιδεία") and skill ("τέχνη") of a scientist, defining the ideal of a modern human-transfessional.…”
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Alterations in mRNA level of proteins related to redox state and mitochondria in an Alzheimer’s disease animal model: Promising targets in neuroprotection by Sylwia Żulińska, Przemysław L. Wencel, Kinga Czubowicz, Joanna B. Strosznajder

“…This study aimed to determine the expression of genes encoding superoxide dismutases (SOD1, SOD2), poly(ADP-ribose) polymerases (PARPs) and sirtuins (SIRTs). …”
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Investigating the functional and structural effect of non-synonymous single nucleotide polymorphisms in the cytotoxic T-lymphocyte antigen-4 gene: An in-silico study. by Md Mostafa Kamal, Kazi Fahmida Haque Shantanu, Shamiha Tabassum Teeya, Md Motiar Rahman, A K M Munzurul Hasan, Douglas P Chivers, Tanveer A Wani, Atekah Hazzaa Alshammari, Mahesh Rachamalla, Francisco Carlos da Silva Junior, Md Munnaf Hossen

“…Out of these, 186 missense variants (5.93%), 1491 intron variants (47.57%), and 91 synonymous variants (2.90%), while the remaining SNPs were unspecified. We utilized SIFT, PolyPhen-2, PROVEAN, and SNAP for identifying deleterious nsSNPs, and SNPs&GO, PhD SNP, and PANTHER for verifying risk nsSNPs in the CTLA4 gene. …”
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Association between the aromatase (CYP19A1) gene variant rs10046 and cardiovascular risk in postmenopausal women by Betânia Rodrigues dos Santos, Gislaine Casanova, Thais Rasia da Silva, Karen Oppermann, Poli Mara Spritzer

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Determination of Ischemia Onset Based on Automatically Generated Spectralis SD-OCT Values in Acute Central Retinal Artery Occlusion by Maria Casagrande, Robert Kromer, Daniel A. Wenzel, Sven Poli, Martin S. Spitzer, Vasyl Druchkiv, Maximilian Schultheiss, Spyridon Dimopoulos

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Synthetic Receptors Decorated on Nanoparticles for Selective and Sensitive Glyphosate Detection by Ilgım Gokturk, Mamajan Ovezova, Gaye Ezgi Yilmaz, Deniz Turkmen, Fatma Yilmaz, Adil Denizli

“…Abstract Herein, an innovative glyphosate imprinted poly(hydroxyethyl methacrylate-N-methacroyl-(L)-phenylalanine methyl ester nanoparticles (MIP@NPs) based plasmonic nanosensor featured with high sensitivity and selectivity was constructed by using the molecular imprinting technique and used for real-time glyphosate detection. …”
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Intrinsically Noncombustible Thermosets from Sulfur-Containing Epoxy Resin and Benzoxazines: Evaluation of Thermal and Mechanical Properties by Ya Lyu, Haibo Fan, Liliang Qiu

“…A TBP-fa/EPS copolymer with an epoxy content of 70% had nearly the same storage modulus (2,206 MPa) at 50°C as poly(BA-a) and thus similar mechanical properties. …”
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Effects of desulfurized gypsum on shrinkage behavior of alkali-activated slag (AAS) and hybrid alkali-activated cement (HAC) by Lili Xue, Zhenkun Ni, Zhengning Zhou, Zuhua Zhang, Houren Xiong, Hao Wang, Xifeng Zhuge, Hongfei Liu

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Impact of R-loops on oncogene-induced replication stress in cancer cells by Heuzé, Jonathan, Lin, Yea-Lih, Lengronne, Armelle, Poli, Jérôme, Pasero, Philippe

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System Pharmacological Approach to Investigate and Validate Multitargeted and Therapeutic Effect of Furocoumarins of Apium graveolens L. for Treatment of Kidney Disease by null Yasheshwar, null Gaurav, Rustam Ekkbal, Prem Gupta, Rajendra Gyawali

“…Several furocoumarins of Apium graveolens were screened from online databases. Network biology and poly-pharmacology analyses were performed to investigate the multitarget therapeutic effect of furocoumarins. …”
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